刘珊珊


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教育经历
学士，哈尔滨医科大学，预防医学专业，2002年
硕士，哈尔滨医科大学，遗传学专业，2006年
博士，哈尔滨工业大学，生物医学工程专业，2012年
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办公电话：**
Email: lss@szu.edu.cn
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主要工作经历
2012年~2015年?苏州大学，现代丝绸国家工程实验室，讲师
2015年至今，深圳大学，医学部，肿瘤研究中心，讲师
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研究方向
肿瘤分子生物学
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科研项目（包括主持和参与的）
主持项目
1.国家自然科学基金青年项目：“仿细胞外基质丝蛋白多孔支架对干细胞行为的调控机制研究”（**），25万，2015年1月-2017年12月。
2.江苏省科技厅自然科学基金青年项目：“仿细胞外基质丝蛋白多孔支架对干细胞行为影响研究”（BK**），30万，2014年7月-2017年6月。
参与项目
1.国家自然科学基金重点项目，“人肺癌细胞MARVELD1的核相互作用分子及影响粘着斑复合体动态组装机制的研究”（**），2009年1月-2011年12月。
2.国家自然科学基金面上项目，“丝蛋白三维结构的构建及其对细胞生长和分化的作用”（**），2012年1月-2015年12月。
3.国家自然科学基金面上项目：“以丝蛋白为基质真皮微环境的仿生构建及促创面血管化修复机制研究”（**），2014年1月-2017年12月。
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代表性成果
论文（#表示并列一作，按时间倒序排列）
1.Liying Xiao^#,?Shanshan Liu^#, Danyu Yao, Zhanzhao Ding, Zhe Fan, Qiang Lu, and David L Kaplan. Fabrication of Silk Scaffolds with Nanomicroscaled Structures and Tunable Stiffness. Biomacromolecules. 2017,18(7):2073-2079. (IF:5.667)
2.Hongchun Wu^#,?Shanshan Liu^#, Liying Xiao^#, Xiaodan Dong, Qiang Lu, and David L Kaplan. Injectable and pH-Responsive Silk Nanofiber Hydrogels for Sustained Anticancer Drug Delivery. ACS Applied Materials and Interfaces. 2016, 8:17118-17126.
3.Hongyan Han^#, Hongyan Ning^#,?Shanshan Liu^#, Qiang Lu, Zhihai Fan, Haijun Lu, Guozhong Lu, and David L Kaplan, Silk Biomaterials with Vascularization Capacity. Advanced functional materials, 2016, 26(3):421-436. (IF: 11.8)
4.Yuanfei Yao, Ming Shi,?Shanshan Liu, and Yu Li, MARVELD1 modulates ?cell surface morphology and suppresses epithelial-mesenchymal transition in non-small cell lung cancer. Mol Carcinog. 2016, 55(11):1714-1727. (IF: 4.808)
5.Shanshan Liu^#, Lijie Liu^#, Liying Xiao, Qiang Lu, Hesun Zhu, and , Design of ? ? ? ?Silk-vaterite microsphere systems as drug carriers with pH-responsive release behavior. Journal of Materials Chemistry B, 2015, 3(42):8314-8320. (IF: 4.726)
6.Xiaowei Huang, Shumeng Bai, Qiang Lu, Xi Liu,?Shanshan Liu,?and?Hesun Zhu.?Osteoinductive-nanoscaled silk/HA composite scaffolds for bone tissue engineering application. J. Biomed. Mater. Res. B.?2015, 103(7): 1402-1414?. (IF:?2.328)
7.Yazhen Pei, Xi Liu,?Shanshan Liu,?Qiang Lu, Jing Liu, David L Kaplan,?and?Hesun Zhu. Mild process to design silk scaffolds with reduced?β-sheet?structure and various topogarphies at nanometer scale. Acta Biomaterialia. 2015,13:168-176. (IF: 6.025)
8.Fangfang Han^#,?Shanshan Liu^#, Xi Liu, Yazhen Pei, Shumeng Bai, Huijing Zhao, QiangLu, Fengguo Ma, David L Kaplan, and Hesun Zhu. Woven silk fabric-reinforced silk nanofibrous scaffolds for regenerating load-bearing soft tissues. Acta Biomaterialia. 2014, 10(2): 921-930. (IF: 6.025)
9.Guozhong Lu^#,?Shanshan Liu^#,?Shasha Lin, David L Kaplan, Qiang Lu. Silk porous scaffolds with nanofibrous microstructures and tunable properties. Colloids Surf B Biointerfaces. 2014, 120C:28-37. (IF: 4.152)
10.Weiqin Sheng, Jing Liu,?Shanshan Liu, Qiang Lu, David L Kaplan, Hesun Zhu. One-step synthesis of biocompatible magnetite/silk fibroin core shell nanoparticles. Journal of Materials Chemistry B. 2014, 2: 7394-7402. (IF: 4.726)
11.Xiaowei Huang, Xi Liu,?Shanshan Liu, Aili Zhang, Qiang Lu, DL. Kaplan, and Hesun Zhu. Biomineralization regulation by nano-sized features in silk fibroin proteins: synthesis of water-dispersible nano-hydroxyapatite. J. Biomed. Mater. Res. B. 2014, 102(8): 1720-1729. (IF:?2.328)?
12.Shasha Lin, Guozhong Lu,?Shanshan Liu, Shumeng Bai, Xi Liu, Qiang Lu,??Baoqi Zuo, DL Kaplan, Hesun Zhu. Nanoscale Control of Silks for Nanofibrous??Scaffold Formation with Improved Porous Structure. J. Mater. Chem. B. 2014, 2(17):?2622- 2633. (IF: 4.726)
13.Shumeng Bai,?Shanshan Liu, Cencen Zhang, Weian Xu, Qiang Lu, Hongyan Han, David L. Kaplan, Hesun Zhu. Controllable transition of silk fibroin nanostructures: an insight into in vitro silk self-assembly process. Acta Biomaterialia. 2013, 9(8):?7806-7813. (IF: 5.684)
14.Shanshan Liu^#, Chaofei Dong^#, Guozhong Lu, Qiang Lu, David L Kaplan,?and?Hesun Zhu. Bilayered vascular grafts based on silk proteins. Acta Biomaterialia. 2013, 9(11): 8991-9003. (IF: 5.684)
15.Shan Wang, Jianran Hu, Yuanfei Yao, Ming Shi, Lei Yue, Fang Han, Hao Zhang, Jie He,?Shanshan Liu, and Yu Li. MARVELD1 regulatesintegrin β1-mediated cell adhesion and actin organization via inhibiting its pre-mRNA processing. International journal of biochemistry & cell biology. 2013, 45(11):?2679-2687. (IF: 4.24)
16.Shanshan Liu^#, Hongxia Zheng^#, Huadong Jiang, Jie He, Yang Yu, Youpeng Qu, Lei Yue, Yao Zhang, and Yu Li. Identification and characterization of a novel gene,?c1orf109, encoding a CK2 substrate that is involved in cancer cell proliferation. Journal of Biomedical Science, 2012, 19:?49. (IF: 2.458)
17.Hongxia Zheng^#,?Shanshan Liu^#, Weiming Tian, Hongji Yan, Yao Zhang,?and?Yu Li. A three-dimensional in vitro culture model for primary neonatal rat ventricular myocytes. Current Applied Physics, 2012, 12(3): 826-833. (IF: 1.814)
18.Shanshan Liu^#, Xiangmei Chen, Hongxia Zheng, Shuliang Shi,?and?Yu Li. Knockdown of Rab5a expression decrease cancer cell motility and invasion by integrin-mediated pathway. Journal of Biomedical Science, 2011, 18:?58. (IF: 2.458)
19.Fanli Zeng, Yanyan Tian, Shuliang Shi, Qiong Wu,?Shanshan Liu, Hongxia Zheng, Lei Yue, and Yu Li. Identification of mouse MARVELD1 as a microtubule associated protein that inhibits cell cycle progression and migration. Moleculesand Cells, 2011, 31: 267-274. (IF: 2.178)
20.Qianqian Xu, Fengwei Zhang, Hongjun He, Shengqiang Xu, Kai Li,?Shanshan Liu, Yu Li, and Qiong Wu. Expression profile of mouse Mterfd2, a novel component of the mitochondrial transcription termination factor (MTERF) family. Genes. Genet. Syst. 2011, 86: 269-275. (IF: 1.132)
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