研究领域
招生信息
教育背景
工作经历
专利与奖励
出版信息
基本信息
娄春波 男 中国科学院深圳先进技术研究院
电子邮件:louchunbo@gmail.com
通信地址:深圳市南山区西丽深圳大学城学苑大道1068号
邮政编码:518055
研究领域
人工生命体设计;哺乳细胞基因线路设计与应用;有限代繁殖的病原菌疫苗;人工生命体的安全性与可控性;靶向巨噬细胞胞内结核杆菌的人工噬菌体设计
招生信息
招硕士生和博士生.招生专业
071010-生物化学与分子生物学086000-生物与医药0710Z2-计算生物学招生方向
合成生物学理论生物学定量生物学教育背景
2003-09--2009-06 北京大学物理学院与理论生物中心 软凝聚态,博士1999-09--2003-07 武汉大学,物理学院 物理学学士
工作经历
工作简历
2011-09~2013-01,麻省理工学院(MIT),博士后2009-08~2011-08,加州大学旧金山分校(UCSF),博士后专利与奖励
专利成果
( 1 ) Synthetic Biology Tools, 发明, 2013, 第 1 作者, 专利号: US Patent Application No: 2013/0005,590( 2 ) Methods and Kits For Fragmenting DNA, 发明, 2016, 第 3 作者, 专利号: U.S. Patent Application No. 62/156,417. /PCT/IL2016/050394( 3 ) Novel oligo-linker-mediated DNA assembly method and applications thereof, 发明, 2016, 第 1 作者, 专利号: U.S. Patent Application No. 2016/** A1( 4 ) 基于CRISPR/Cas9和酿酒酵母细胞内源的同源重组的分子克隆方法, 发明, 2015, 第 1 作者, 专利号: CNA( 5 ) 细胞间通讯系统的全新设计方法、细胞 间通讯系统及其用途, 发明, 2020, 第 1 作者, 专利号: 2.X出版信息
发表论文
(1)A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts.,Nucleic acids research,2019,通讯作者(2)人工遗传改造生命体的防逃逸技术研究进展,有机化学,2018,通讯作者(3)Engineering the Ultrasensitive Transcription Factors by Fusing a Modular Oligomerization Domain,ACS synthetic biology,2018,通讯作者(4)Insulated transcriptional elements enable precise design of genetic circuits,Nature communications,2017,通讯作者(5)人工基因元件的生理学研究进展,生物工程学报,2017,通讯作者(6)Construction of an easy-to-use CRISPR-Cas9 system by patching a newly designed EXIT circuit,Journal of biological engineering,2017,通讯作者(7)Intermediate-sensor assisted push–pull strategy and its application in heterologous deoxyviolacein production in Escherichia coli,Metabolic engineering,2016,第7作者(8)Semi-rational approach for ultra-high poly (3-hydroxybutyrate) accumulation in Escherichia coli by combining one-step library construction and high-throughput screening,ACS synthetic biology,2016,通讯作者(9)Paired design of dCas9 as a systematic platform for the detection of featured nucleic acid sequences in pathogenic strains,ACS synthetic biology,2016,通讯作者(10)Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces,PNAS,2015,通讯作者(11)Cas9-Assisted Targeting of CHromosome segments CATCH enables one-step targeted cloning of large gene clusters,Nature communs,2015,通讯作者(12)Ribozyme-based “insulator parts” buffer synthetic circuits from genetic context,Nature Biotechnology,2012,第1作者(13)Genetic programs constructed from layered logic gates in single cells,Nature,2012,第2作者(14)Synthesizing a novel genetic sequential logic circuit, Molecular Systems Biology,2010,第1作者(15)A molecular model for persister in E. coli,Journal of Theoretical Biology,2008,第1作者(16)A quantitative study of lambda-phage Switch and its components,Biophysical Journal,2007,第1作者2013 © 中国科学院大学,网络信息中心.