研究领域
招生信息
教育背景
工作经历
教授课程
专利与奖励
出版信息
科研活动
合作情况
基本信息
张鹏飞男硕导中国科学院深圳先进技术研究院
电子邮件： pf.zhang@siat.ac.cn
通信地址： 深圳市南山区学苑大道1068号
邮政编码：
研究领域
1） 聚集诱导发光2） 纳米生物分析
3） 纳米医学
4）生物材料
招生信息
1）分析化学2） 功能材料
3） 化学生物学/纳米生物学
招生专业
0703Z1-化学生物学070305-高分子化学与物理083100-生物医学工程招生方向
聚集发光材料核酸纳米技术微纳机器人教育背景
2015-08--2018-11香港科技大学博士研究生2002-09--2009-07湖南大学硕士研究生学历
博士工作经历
工作简历
2018-12~现在,中国科学院深圳先进技术研究院,副研究员2011-07~2015-08,中国科学院深圳先进技术研究院,助理研究员2009-07~2011-07,中国科学院深圳先进技术研究院,研究助理教授课程
化学生物学专利与奖励
奖励信息
（1） 纳米智能材料的化学标记与生物示踪研究, 二等奖, 省级, 2016（2） 纳米生物智能材料的肿瘤诊疗一体化研究, 二等奖, 市地级, 2015专利成果
（ 1 ） LUMINOGENS FOR BIOLOGICAL APPLICATIONS, 发明, 2017, 第 5 作者, 专利号: WO（ 2 ） NIR-II Emissive Luminogens, 发明, 2019, 第 2 作者, 专利号: WOA1（ 3 ） AIEGENS FOR CANCER CELL IMAGING, 发明, 2017, 第 5 作者, 专利号: WO.出版信息
长期从事多功能发光纳米材料合成、修饰及其生物分析及医学相关应用研究，已在J.Am.Chem.Soc.(化学顶级期刊), Angewandte Chemie International Edition, (化学顶级期刊), Analytical Chemistry (分析化学顶级期刊), Advanced Materials（材料科学顶级期刊）, Advanced Functional Materials, ACS NANO, Biomaterials等国际期刊发表发表论文50 余篇（第一作者/通讯作者文章15篇，其中影响因子大于10的论文4篇)发表论文
（1）Fluorescence Self‐Reporting Precipitation Polymerization Based on Aggregation‐Induced Emission for Constructing Optical Nanoagents,Angewandte Chemie International Edition,2020,第1作者（2）Ratiometric Photoacoustic Chemical Sensor for Pd2+ Ion,Analytical Chemistry,2020,通讯作者（3）Highly Stable and Bright NIR-II AIE Dots for Intraoperative Identification of Ureter,ACS Appl. Mater. Interfaces,2020,第1作者（4）Development of AIEgen–montmorillonite nanocomposite powders for computer-assisted visualization of latent fingermarks,Materials Chemistry Frontiers,2020,通讯作者（5）On-site visual discrimination of transgenic food by water-soluble DNA-binding AIEgens,Materials Chemistry Frontiers,2019,通讯作者（6）Mitochondria-Localized Self-Reporting Small-Molecule-Decorated Theranostic Agents for Cancer-Organelle Transporting and Imaging,ACS Applied Bio Materials,2019,通讯作者（7）Lysosome-Targeting Red-Emitting Aggregation-Induced Emission Probe with Large Stokes Shift for Light-Up in Situ Visualization of β-N-Acetylhexosaminidase,Analytical Chemistry,2019,第4作者（8）An Easily Available Ratiometric Reaction-Based AIE Probe for Carbon Monoxide Light-up Imaging,Analytical Chemistry,2019,通讯作者（9）Monitorable Mitochondria-Targeting DNAtrain for Image-Guided Synergistic Cancer Therap,Analytical Chemistry,2019,通讯作者（10）Scaffolds biomimicking macrophages for a glioblastoma NIR-Ib imaging guided photothermal therapeutic strategy by crossing Blood-Brain Barrier,Biomaterials,2019,通讯作者（11）Rational Design of Perylenediimide-Substituted Triphenylethylene to Electron Transporting Aggregation-Induced Emission Luminogens (AIEgens) with High Mobility and Near-Infrared Emission,Advanced Functional Materials,2018,第4作者（12）Protein-modified conjugated polymer nanoparticles with strong near-infrared absorption: a novel nanoplatform to design multifunctional nanoprobes for dual-modal photoacoustic and fluorescence imaging,Nanoscale,2018,第1作者（13）Red/NIR‐Emissive Benzo[d]imidazole‐Cored AIEgens: Facile Molecular Design for Wavelength Extending and In Vivo Tumor Metabolic Imaging,Advanced Materials,2018,第1作者（14）Recombina nt-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging,Chemical Communications,2018,通讯作者（15）Ultrabright red AIEgens for two-photon vascular imaging with high resolution and deep penetration,Chemical Science,2018,第1作者（16）Polyyne bridged AIE luminogens with red emission: design, synthesis, properties and applications,Journal of Materials Chemistry B,2017,第3作者（17）Aptamer-Decorated Self-Assembled Aggregation-Induced Emission Organic Dots for Cancer Cell Targeting and Imaging,Analytical Chemistry,2017,第1作者（18）Ionization and Anion?π+ Interaction: A New Strategy for Structural Design of Aggregation-Induced Emission Luminogens,Journal of the American Chemical Society,2017,第3作者（19）Observation of Metal Nanoparticles for Acoustic Manipulation,Advanced Science,2017,第7作者（20）The synthesis of novel AIE emitters with the triphenylethene-carbazole skeleton and para-/meta-substituted arylboron groups and their application in efficient non-doped OLEDs,Journal of Materials Chemistry C,2016,第4作者（21）Iron oxide nanoparticles protected by NIR-active multidentate-polymers as multifunctional nanoprobes for NIRF/PA/MR trimodal imaging,Nanoscale,2016,通讯作者（22）Long-decay near-infrared-emitting doped quantum dots for lifetime-based in vivo pH imaging,Chemical Communications,2015,第1作者（23）Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging,Nanoscale,2015,第1作者（24）Robust ICG Theranostic Nanoparticles for Folate Targeted Cancer Imaging and Highly Effective Photothermal Therapy,ACS Applied Materials & Interfaces,2014,第6作者（25）Aptamer-mediated indirect quantum dot labeling and fluorescent imaging of target proteins in living cells,Nanotechnology,2014,第1作者（26）Near-Infrared-Emitting Two-Dimensional Codes Based on Lattice-Strained Core/(Doped) Shell Quantum Dots with Long Fluorescence Lifetime,Advanced Materials,2014,第1作者（27）Smart Human Serum Albumin-Indocyanine Green Nanoparticles Generated by Programmed Assembly for Dual-Modal Imaging-Guided Cancer Synergistic Phototherapy,ACS NANO,2014,第9作者（28）Noninvasive Visualization of Respiratory Viral Infection Using Bioorthogonal Conjugated Near-Infrared-Emitting Quantum Dots,ACS NANO,2014,第1作者（29）Highly Bright and Compact Alloyed Quantum Rods with Near Infrared Emitting: a Potential Multifunctional Nanoplatform for Multimodal Imaging In Vivo,Advanced Functional Materials,2014,第1作者（30）Folate Receptor-Targeting Gold Nanoclusters as Fluorescence Enzyme Mimetic Nanoprobes for Tumor Molecular Colocalization Diagnosis,Theranostics,2014,第6作者（31）Near infrared fluorescence resonance energy transfer based aptamer biosensor for insulin detection in human plasma,Chemical Communications,2014,第3作者（32）Functionalized quantum dots induce proinflammatory responses in vitro: the role of terminal functional group-associated endocytic pathways,Nanoscale,2013,第3作者（33）Hybrid gold–gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo,Nanoscale,2013,第3作者（34）One-step synthesis of peptide-programmed QDs as ready-to-use nanoprobes,Chemical Communications,2013,通讯作者（35）Single-Step Assembly of DOX/ICG Loaded Lipid–Polymer Nanoparticles for Highly Effective Chemo-photothermal Combination Therapy,ACS NANO,2013,第8作者（36）Protein-assisted fabrication of nano-reduced graphene oxide for combined in vivo photoacoustic imaging and photothermal therapy,Biomaterials,2013,第9作者（37）Polypeptide cationic micelles mediated co-delivery of docetaxel and siRNA for synergistic tumor therapy,Biomaterials,2013,第6作者（38）DNase-activatable fluorescence probes visualizing the degradation of exogenous DNA in living cells,Nanoscale,2012,第3作者（39）Click-Functionalized Compact Quantum Dots Protected by Multidentate-Imidazole Ligands: Conjugation-Ready Nanotags for Living-Virus Labeling and Imaging,Journal of the American Chemical Society,2012,第1作者（40）PEI protected aptamer molecular probes for contrast-enhanced in vivo cancer imaging,Biomaterials,2012,第5作者（41）Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging,Biomaterials,2012,第5作者（42）Cation exchange in aptamer-conjugated CdSe nanoclusters: a novel fluorescence signal amplification for cancer cell detection,Chemical Communications,2012,第3作者（43）A fast synthesis of near-infrared emitting CdTe/CdSe quantum dots with small hydrodynamic diameter for in vivo imaging probes,Nanoscale,2011,第1作者（44）Planar AIEgens with Enhanced Solid‐State Luminescence and ROS Generation for Multidrug‐Resistant Bacteria Treatment,Angewandte Chemie International Edition,2002,第5作者科研活动
科研项目
（ 1 ） 基于体内点击化学的光学纳米探针的构建及 其活体成像研究, 主持,国家级,2016-01--2018-12（ 2 ） “点击化学”纳米探针用于病毒活体示踪研究, 主持,省级,2015-01--2016-12（ 3 ） 基于点击化学的量子点原位生物标记新方法研究, 主持,市地级,2014-01--2015-12（ 4 ） 王宽诚率先人才计划-卢嘉锡国际团队-纳米免疫与诊疗一体化国际团队, 参与,部委级,2019-01--2021-12（ 5 ） 智能响应AIE-DNA 纳米火车载药系统用于精准纳米医学研究, 主持,部委级,2020-01--2021-12（ 6 ） 仿生纳米/聚集态可视化诊疗一体化技术, 主持,市地级,2020-01--2021-12参与会议
（1）AIE新材料在生物医疗技术方面的发展趋势第十二届中国生物产业大会2019-06-10（2）AIEgens-Based Photophysical Tools for Biomedical Research 第十六次中国暨国际生物物理大会2018-08-24（3）Aptamer-AIE Dots: A Promising Tumor-Targeting Nanoprobe for Translational Medicine2017-06-21合作情况
中国香港-香港科技大学/香港大学/香港城市大学中国澳门-澳门大学/澳门科技大学
澳大利亚-新南威尔士大学
意大利-米兰大学
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