研究领域
招生信息
教育背景
工作经历
出版信息
科研活动
合作情况
指导学生
王国成男博导中国科学院深圳先进技术研究院
电子邮件： gc.wang@siat.ac.cn
通信地址： 深圳市南山区西丽深圳大学城学苑大道1068号
邮政编码：
研究领域
1. 硬组织再生和生物密封（biological sealing）；
2. 细胞/组织微环境设计及行为调控；
3. 表面图案化设计及应用开发研究；
4. 抗菌生物材料；
5. 纳米生物材料。
招生信息
材料和化学相关的博士/硕士研究生
招生专业
070304-物理化学071009-细胞生物学071005-微生物学招生方向
生物材料表面改性基于材料界面性能的细胞行为调控骨替换和再生材料教育背景
2004-09--2009-07中国科学院上海硅酸盐研究所博士2000-09--2004-07天津城建大学本科学历
博士研究生
学位
博士
工作经历
工作简历
2013-06~2015-06,西班牙CIC biomaGUNE生物材料研究中心,博士后2009-10~2012-12,澳大利亚悉尼大学（the University of Sydney）,博士后2009-07~2009-10,中国科学院上海硅酸盐研究所,助理研究员社会兼职
2019-04-29-今,波兰科学基金合作专家（FN-SOP）,2017-12-01-今,"Alliance for Design and Application in Tissue Engineering" International Partner,
2016-03-31-2019-03-31,中国医促会骨科生物材料学组委员暨骨科分会委员,
出版信息
发表论文
（1）Enhancement and orchestration of osteogenesis and angiogenesis by a dual-modular design of growth factors delivery scaffolds and 26SCS decoration,Biomaterials,2020,通讯作者（2）Electron transfer correlated antibacterial activity of biocompatible graphene Nanosheets-TiO2 coatings,Carbon,2020,通讯作者（3）Strontium modulates osteogenic activity of bone cement composed of bioactive borosilicate glass particles by activating Wnt/β-catenin signaling pathway,Bioactive Materials,2020,第10作者（4）Bispecific T-cell Engager (BiTE) Immunotherapy of Ovarian Cancer Based on MIL-88A MOF/MC Gene Delivery system,Applied Materials Today,2020,通讯作者（5）Strong mineralization ability of strontium zinc silicate: Formation of a continuous biomorphic mineralized layer with enhanced osteogenic activity,Colloids and Surfaces B: Biointerfaces,2019,通讯作者（6）Antibacterial Mesoporous Titania Films with Embedded Gentamicin and Surface Modified with Bone Morphogenetic Protein 2 to Promote Osseointegration in Bone Implants,Advanced Materials Interfaces,2019,第7作者（7）3D Printing of Mechanically Stable Calcium-Free Alginate-Based Scaffolds with Tunable Surface Charge to Enable Cell Adhesion and Facile Biofunctionalization,Advanced Functional Materials,2019,第8作者（8）钛种植体表面CuO和Nb2O5共掺杂TiO2涂层的制备及抗菌性能和生物相容性,中国表面工程,2019,通讯作者（9）Ca、Ag掺杂对TiO2涂层结构、体外矿化和抗菌性能的影响,硅酸盐学报,2019,第5作者（10）Modulation of the Micro/Nanotopography of Plasma Sprayed Biomedical Coatings for Enhanced Osteogenic Activity,Surface Review and Letters,2018,通讯作者（11）Potential of niobium-based thin films as a protective and osteogenic coating for dental implants: The role of the nonmetal elements,Materials Science and Engineering C,2018,通讯作者（12）Layered titanates with fibrous nanotopographic features as reservoir for bioactive ions to enhance osteogenesis,Applied Surface Science,2018,通讯作者（13）Enhanced osteogenic activity of Ti alloy implants by modulating strontium configuration in their surface oxide layers,RSC Advances,2018,通讯作者（14）Application of MBG as a coating material on mechanically stronger but less degradable ceramic scaffolds for enhanced osteogenesis,Materials Letters,2018,通讯作者（15）抗菌元素对纳米TiO2涂层结构和性能的影响,表面工程,2018,第7作者（16）Bio-inspired titanium coatings: Self-assembly of collagen-alginate films for enhanced osseointegration,Journal of Materials Chemistry B,2016,第2作者（17）Enhancing orthopedic implant biocompatibility: refining the nanotopography,Nanomedicine,2015,第1作者（18）Interfacial Reaction-Driven Formation of Silica Carbonate Biomorphs with Subcellular Topographical Features and Their Biological Activity,ACS Applied Materials & Interface,2015,第1作者（19）Synergistic effects of hierarchical hybrid micro/nanostructures on the biological properties of Ti-based orthopaedic implants,RSC Advances,2015,通讯作者（20）Nb-C nanocomposite films with enhanced biocompatibility and mechanical properties for hard-tissue implant applications,ACS Applied Materials & Interface,2015,通讯作者（21）Refining nanotopographical features on bone implant surfaces by altering surface chemical compositions,RSC Advances,2014,通讯作者（22）Ordered HAp nanoarchitecture formed on HAp/TCP bioceramics by ‘nanocarving’ and mineralization deposition and its potential use for guiding cell behavior,Journal of Materials Chemistry B,2013,第1作者（23）The synergistic effect of hierarchical micro/nano-topography and bioactive ions for enhanced osseointegration,Biomaterials,2013,第1作者（24）Delicate refinement of surface nanotopography by adjusting TiO2 coating chemical composition for enhanced interfacial biocompatibility,ACS Applied Materials & Interfaces,2013,通讯作者（25）Baghdadite Ceramics Modulate the Crosstalk between Human Adipose Stem Cells and Osteoblasts for Bone Regeneration,Tissue Engineering A,2013,第2作者（26）Activation and promotion of adipose tissue-derived mesenchymal stem cells by tumour necrosis factor-alpha preconditioning for bone tissue engineering,Journal of Cellular Physiology,2013,第2作者（27）A facile method to in-situ formation of hydroxyapatite single crystal architecture for enhanced osteoblast adhesion,Journal of Materials Chemistry,2012,第1作者（28）Short-term Exposure to Tumour Necrosis Factor-alpha Enables Human Osteoblasts to Direct Adipose Tissue-Derived Mesenchymal Stem Cells into Osteogenic Differentiation,Stem Cells and Development,2012,第2作者（29）Porous scaffolds with tailored reactivity modulate in-vitro osteoblast responses,Materials Science and Engineering C,2012,第1作者（30）Bone biomimetic microenvironment induces osteogenic differentiation of adipose tissue-derived mesenchymal stem cells,Nanomedicine,2012,第3作者（31）Nanostructured glass-ceramic coatings for orthopaedic applications,Journal of the Royal Society Interface,2011,第1作者（32）Enhanced effects of nano-scale topography on the bioactivity and osteoblast behaviors of micron rough ZrO2 coatings,Colloids and Surface B: Biointerface,2011,第1作者（33）Functional coatings or films for hard-tissue applications,Materials,2010,第1作者（34）Microstructure, bioactivity and osteoblast behavior of monoclinic zirconia coating with nanostructured surface,Acta Biomaterialia,2010,第1作者（35）In vitro bioactivity and phase stability of plasma-sprayed nanostructured 3Y-TZP coatings.,Acta Biomaterialia,2009,第1作者（36）Plasma-sprayed CaTiSiO5 ceramic coating on Ti-6Al-4V with excellent bonding strength, stability and cellular bioactivity,Journal of the Royal Society Interface,2009,第4作者（37）等离子喷涂纳米氧化锆涂层研究进展,中国表面工程,2009,第3作者（38）Phase composition and in-vitro bioactivity of plasma sprayed calcia stabilized zirconia coatings,Surface and Coatings Technology,2008,第1作者发表著作
（1）Bioceramics for skeletal bone regeneration,Woodhead Publishing,2014-08,第1作者科研活动
科研项目
（ 1 ） 新型仿生骨材料的关键技术研发, 主持,省级,2016-01--2018-01（ 2 ） 骨科植入体表面化学和微纳拓扑结构的协同调控及其对生物学性能的影响研究, 主持,省级,2015-09--2016-09（ 3 ） 新型高骨诱导活性人工关节涂层的研发, 主持,省级,2017-01--2018-12（ 4 ） 华南生物医用材料与植入器械创新示范基地, 主持,国家级,2017-07--2020-12（ 5 ） 组织工程骨仿生活化及快速血管化研究, 主持,省级,2017-06--2020-06（ 6 ） 生物活性陶瓷表面微环境预调制及其对巨噬细胞行为和骨再生的影响机制, 主持,国家级,2019-01--2022-12（ 7 ） 钛合金表面原位介孔化及生长因子负载的促骨整合作用研究, 主持,省级,2018-05--2021-04（ 8 ） 生物材料与组织工程制品调控的免疫微环境对组织再生的影响及机制研究, 参与,国家级,2018-09--2021-06参与会议
（1）Nano-topographic modification of biomaterials for enhanced biological responses2019-06-05（2）基于界面反应的生物形态碳酸锶晶体的形成及其对生物活性的影响研究中国生物材料大会2015-11-19（3）Nobium-Carbon nanocomposite films for orthopaedic implant applications2015-10-24（4）Novel method to in-situ formation of hydroxyapatite single crystal architecture for enhanced bioactivity2012-08-28（5） Biomimetic single crystal surface Engineering of Bioceramics for enhanced wettability and osteoblast attachment2012-06-01合作情况
The University of Sydney, Australia-Prof. Hala ZreiqatCIC biomaGUNE, Spain-Prof. Sergio Moya
School of Engineering, Universidad Militar Nueva Granada, Colombia-Prof. Willian Aperador
NanoBioMedical Center, Adam Mickiewicz University, Poland-Prof. Emmerson Coy
Centro de Investigación en Química Aplicada (CIQA), Mexico-Prof. Ron Ziolo
项目协作单位
深圳第二人民医院，第四军医大学，上海长海医院
指导学生
现指导学生卢丹萍硕士研究生085204-材料工程
邱实硕士研究生085204-材料工程
联合培养硕士生
丘才杰（常州大学）；
陈晓艺（中科大纳米学院）；
孙伟（中科大纳米学院）；
吴犇（常州大学）。
?
2013 © 中国科学院大学，网络信息中心.
