姓名：黎锦明
学历：博士
职称：
职务：研究员
研究方向：无机纳米材料在肿瘤/干细胞治疗中的应用
联系电话：
电子邮箱：lijinm@scnu.edu.cn
通讯地址：
个人主页：

个人简历
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出版著作
科研项目
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2012.6博士毕业于中山大学化学院，获理学博士学位。
2012.9-2014.2 新加坡南洋理工大学 博士后
2014.2-2016.8 香港中文大学 博士后
2016.8-2017.8 加州大学河滨分校 博士后
2017.9-至今 华南师范大学生物光子学研究院 研究员




目前为止，已在Nano Lett.,J.Am.Chem.Soc.,Angew.Chem.Int.Ed., Adv.Funct. Mater., Biomaterials, ACS Appl. Mater. Interfaces, Adv. Healthcare Mater., Nanoscale, J. Mater. Chem. B等著名杂志期刊发表SCI论文28篇，他引600多次，H=10。（^#共同第一作者，^*通讯作者）


2020年
1. Qian Wu, Kaipeng Wang, Xichao Wang, Guohai Liang^* and Jinming Li^*. Delivering siRNA to control osteogenic differentiation and real-time detection of cell differentiation in human mesenchymal stem cells using multifunctional gold nanoparticles. J.Mater. Chem. B, 2020, 8, 3016.
2. Kaipeng Wang, Qian Wu, Xichao Wang, Guohai Liang, Anli Yang^* and Jinming Li^*. Near-infrared control and real-time detection of osteogenic differentiation in mesenchymal stem cells by multifunctional upconversion nanoparticles. Nanoscale, 2020, 12, 10106.
3. Wen-Xue Lei, Zi-Shuai An, Bai-Hong Zhang, Qian Wu, Wen-Jun Gong, Jin-Ming Li^* and Wen-Li Chen^*. Construction of gold-siRNA NPR1 nanoparticles for effective and quick silencing of NPR1 in Arabidopsis thaliana. RSC Adv., 2020, 10, 19300.


2019年
1. Jinming Li,^# Chris Wai Tung Leung,^# Dexter Siu Hong Wong, Jianbin Xu, Rui Li, Yueyue Zhao, Chris Yu Yee Yung, Engui Zhao, Ben Zhong Tang^* and Liming Bian^*. Photocontrolled SiRNA Delivery and Biomarker-Triggered Luminogens of Aggregation-Induced Emission by Up-Conversion NaYF4:Yb3+Tm3+@SiO2 Nanoparticles for Inducing and Monitoring Stem-Cell Differentiation. ACS Appl. Mater. Interfaces 2019, 11, 22074?22084.
2. Jianbin Xu, Qian Feng, Sien Lin, Weihao Yuan, Rui Li, Jinming Li, Kongchang Wei, Xiaoyu Chen, Kunyu Zhang, Yanhua Yang, Tianyi Wu, Bin Wang, Meiling Zhu, Rui Guo, Gang Li^* and Liming Bian^*. Injectable stem cell-laden supramolecular hydrogels enhance in situ osteochondral regeneration via the sustained co-delivery of hydrophilic and hydrophobic chondrogenic molecules. Biomaterials 210 (2019) 51-61.


2018年
1. Rui Li,^# Jinming Li,^# Jianbin Xu, Dexter Siu Hong Wong, Xiaoyu Chen, Weihao Yuan, Liming Bian^*. Multiscale reconstruction of a synthetic biomimetic micro-niche for enhancing and monitoring the differentiation of stem cells. Biomaterials 173 (2018) 87-99.
2. Jinming Li,^# Honghong Wu,^# Israel Santana, Mackenzie Fahlgren, and Juan Pablo Giraldo^*. Standoff Optical Glucose Sensing in Photosynthetic Organisms by a Quantum Dot Fluorescent Probe. ACS Appl. Mater. Interfaces 2018, 10, 28279?28289.
3. Jinming Li,^# Wayne Yukwai Lee,^# Tianyi Wu, Chris Waitung Leung, Jianbin Xu, Dexter Siuhong Wong, Rui Li, Gang Li,* Ben Zhong Tang,* and Liming Bian*. Detection of Matrix Metallopeptidase 13 for Monitoring Stem Cell Differentiation and Early Diagnosis of Osteoarthritis by Fluorescent Light-Up Probes with Aggregation-Induced Emission Characteristics. Adv. Biosys. 2018, **.
4. Heemin Kang, Kunyu Zhang, Qi Pan, Sien Lin, Dexter Siu Hong Wong, Jinming Li, Wayne Yuk-Wai Lee, Boguang Yang, Fengxuan Han, Gang Li, Bin Li,* and Liming Bian*. Remote Control of Intracellular Calcium Using Upconversion Nanotransducers Regulates Stem Cell Differentiation In Vivo. Adv. Funct. Mater. 2018, **.


2017年
1. Dexter S. H. Wong,^# Jinming Li,^# Xiaohui Yan, Ben Wang, Rui Li, Li Zhang, and Liming Bian*. Magnetically Tuning Tether Mobility of Integrin Ligand Regulates Adhesion, Spreading, and Differentiation of Stem Cells. Nano Lett. 2017, 17, 1685?1695.
2. Rui Li, Jianbin Xu, Dexter Siu Hong Wong, Jinming Li, Pengchao Zhao, Liming Bian*. Self-assembled N-cadherin mimetic peptide hydrogels promote the chondrogenesis of mesenchymal stem cells through inhibition of canonical Wnt/ b -catenin signaling. Biomaterials 145 (2017) 33-43.


2016年
1. Jinming Li, Wayne Yukwai Lee, Tianyi Wu, Jianbin Xu, Kunyu Zhang, Gang Li, Jiang Xia, and Liming Bian*. Multifunctional Quantum Dot Nanoparticles for Effective Differentiation and Long-Term Tracking of Human Mesenchymal Stem Cells In Vitro and In Vivo. Adv. Healthcare Mater. 2016, 5, 1049-1057.
2. Jianbin Xu,^# Jinming Li,^# Sien Lin, Tianyi Wu, Heqin Huang, Kunyu Zhang, Yuxin Sun, Kelvin W. K. Yeung, Gang Li, and Liming Bian*. Nanocarrier-Mediated Codelivery of Small Molecular Drugs and siRNA to Enhance Chondrogenic Differentiation and Suppress Hypertrophy of Human Mesenchymal Stem Cells. Adv. Funct. Mater. 2016, 26, 2463-2472.
3. Jinming Li,^# Yuanyuan Wang,^# Shanshan Xue, Jinghua Sun, Wei Zhang, Ping Hu, Liangnian Ji, Zongwan Mao*. Effective combination treatment of lung cancer cells by single vehicular delivery of siRNA and different anticancer drugs. Int. J. Nanomed. 2016, 11, 4609-4624.
4. Jinming Li, Shanshan Xue and Zong-Wan Mao.* Nanoparticle delivery systems for siRNA-based therapeutics. J. Mater. Chem. B 2016, 4, 6620.
5. Jinming Li,^# Wayne Yukwai Lee,^# Tianyi Wu, Jianbin Xu, Kunyu Zhang, Dexter Siu Hong Wong, Rui Li, Gang Li,* Liming Bian.* Near-infrared light-triggered release of small molecules for controlled differentiation and long-term tracking of stem cells in vivo using upconversion nanoparticles. Biomaterials 2016, 110, 1-10.


2015年
1.JinmingLi,WeiZhang,LiangnianJiandZongwanMao.*ReversalofmultidrugresistanceinMCF-7/AdrcellsbycodeliveryofdoxorubicinandBCL2siRNAusingafolicacid-conjugatedpolyethyleniminehydroxypropyl-β-cyclodextrinnanocarrier.Int. J. Nanomed. 2015,10,3147-3162.
2. Chun Kit Choi, Jinming Li, Kongchang Wei, Yang J. Xu, Lok Wai C. Ho, Meiling Zhu, Chung Hang J. Choi* and Liming Bian.* Agold@polydopaminecore-shellnanoprobeforlong-termintracellulardetectionofmicroRNAsindifferentiatingstemcells.J.Am.Chem.Soc.2015,137,7337.


2014年
1. JinmingLi,FangLiu,Qing Shao , Yuanzeng Min , Marianne Costa, Edwin K. L.Yeow* and Bengang Xing.* Enzyme-responsivecell-penetratingpeptideconjugatedmesoporoussilicaquantumdotnanocarriersforcontrolledreleaseofnucleus-targeteddrugmoleculesandreal-timeintracellularfluorescenceimagingoftumorcells.Adv.HealthcareMater.2014,3,1230-1239.
2. YuanzengMin,JinmingLi,FangLiuandBengangXing.*Near-infraredlight-mediatedphotoactivationofaplatinumantitumorprodrugandsimultaneouscellularapoptosisimagingbyupconversion-luminescentnanoparticles.Angew.Chem.Int.Ed.2014,53,1012-1016.
3.YuanzengMin,JinmingLi,FangLiuandBengangXing.^*Recentadvanceofbiologicalmolecularimagingbasedonlanthanide-dopedupconversion-luminescentnanomaterials.J. Nanomater. 2014,4,129-154.
4.MeixiaZhao,MengZhao,ErzaoZeng,YangLi,JinmingLi,QianCao,CaipingTan,LiangnianJi,ZongwanMao.*Enhancedanti-cancerefficacytocancercellsbydoxorubicinloadedwater-solubleaminoacid-modifiedβ- cyclodextrinplatinumcomplexes.J.Inorg.Biochem.2014,137,31-39.


2013年
1.JinmingLi,YuanyuanWang,WeiZhang,LiangnianJiandZongwanMao.*Lowweightpolyethyleniminecross-linked2-hydroxypopyl-β-cyclodextrinandfolicacidasanefficientandnontoxicsiRNAcarrierforgenesilencingandtumorinhibitionbyVEGFsiRNA. Int. J. Nanomed. 2013,8,2101-2117.
2.LingZhang,QiheYin,JinmingLi,HongyingHuang,QingWuandZongwanMao.*Functionalizationofdendriticpolyethylenewithcationicpoly(p-phenyleneethynylene)enablesefficientsiRNAdeliveryforgenesilencing.J. Mater. Chem. B2013,1,2245-2251.


2012年
JinmingLi,^#YuanyuanWang,^#CaipingTang,LiangnianJiandZongwanMao.* MultifunctionalQD-basedco-deliveryofsiRNAanddoxorubicintoHeLacellsforreversalofmultidrugresistanceandreal-timetracking.Biomaterials2012,33,2780-2790.


2011年
1.JinmingLi,MeixiaoZhao,CaipingTang,LiangnianJiandZongwanMao.*Multifunctionalquantum-dot-basedsiRNAdeliveryforHPV18E6genesilenceandintracellularimaging.Biomaterials2011,32,7978-7987.
2.MeixiaZhao,JinmingLi,CaipingTang,LiangnianJiandZongwanMao.*TargetedcellularuptakeandsiRNAsilencingbyquantum-dotnanoparticlescoatedwithβ-cyclodextrincoupledtoaminoacids.Chem-EurJ.2011,17,5171-5179.




2017年华南师范大学青年拔尖人才科研启动基金，8S0143，150万，主持，在研。

2019年国家自然科学基金面上项目，上转换纳米粒光控诱导干细胞分化及检测分化用于骨质疏松治疗研究，项目批准号：**，58万，主持，在研。