蔡曌研究助理教授


caiz@mail.sustech.edu.cn
生物楼502
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个人简介从事菌群宏基因组学及抗性组学，空气微生物组学等研究， 近五年在Journal of Antimicrobial Chemotherapy，Applied and Environmental Microbiology、Computational and Structural Biotechnology Journal，American Journal of Respiratory and Critical Care Medicine 等SCI杂志发表研究论文10篇。
研究领域从事致病菌宏基因组学及抗性组学、空气微生物组学研究，分析鉴定菌群耐药机制，耐药基因转移机制等方面。

教育背景2012/8-2017/2, 新加坡南洋理工大学, 环境与生命科学工程研究中心, 博士
2008/8-2012/5, 新加坡南洋理工大学, 化学与医药工程学院, 学士



工作经历2020/5-至今 ，南方科技大学，医学院，研究助理教授
2020/3-2020/4，南方科技大学，医学院，高级研究****
2017/4-2020/2, 新加坡南洋理工大学, 环境与生命科学工程研究中心, Research Fellow



近年代表文章1. Peiyan Zhang#,Zhao Cai#,Weibo Wu,Ling Peng,Yinfeng Li,Chuming Chen,Li Chen,Jianming Li,Mengli Cao,Shiyan Feng,Xiao Jiang, Jing Yuan, Yingxia Liu, Liang Yang?, Fuxiang Wang? The novel coronavirus (COVID-19) pneumonia with negative detection of viral ribonucleic acid from nasopharyngeal swabs: A case report，BMC Infectious Diseases, DOI : 10.1186/s12879-020-05045-z
2. Zhenpeng Li#, Zhao Cai#, Zeqiong Cai, Yanhong Zhang, Tongtong Fu, Yongxin Jin, Zhihui Cheng, Shouguang Ji, Weihui Wu, Liang Yang?, Fang Bai? (2020) Extensively Drug-Resistant Molecular Genetic Analysis of An XDR-Pseudomonas aeruginosa ST664 Clone Carrying Multiple Conjugal Plasmids, Journal of Antimicrobial Chemotherapy
3. Tingting Wang#, Zhao Cai#, Xiaolong Shao, Weitong Zhang, Yingpeng Xie, Yingchao Zhang, Canfeng Hua, Stephan C. Schuster, Liang Yang, Xin Deng (2019) The Pleiotropic Effects of c-di-GMP Content in Pseudomonas syringae, Applied and Environmental Microbiology. 2019 Mar 8. pii: AEM.00152-19. doi: 10.1128/AEM.00152-19
4. Zhao Cai#, Yang Liu#, Yicai Chen, Joey Kuok Hoong Yam, Su Chuen Chew, Song Lin Chua, Ke Wang, Michael Givskov and Liang Yang (2015) RpoN Regulates Virulence Factors of Pseudomonas aeruginosa via Modulating the PqsR Quorum Sensing Regulator, International journal of molecular sciences, 2015, 16, 28311–28319
5. Fang Bai#, Zhao Cai#, Liang Yang (2019) Recent progress in experimental and human disease-associated multi-species biofilms, Review, Computational and Structural Biotechnology Journal, 2019, 17, 1234-1244
6. Micheál Mac Aogáin#, Kenny J. X. Lau#, Cai Zhao, Jayanth Kumar Narayana, Rikky W.Purbojati, Daniela I. Drautz-Moses, Nicolas E. Gaultier, Tavleen K. Jaggi, Pei Yee Tiew,
Thun How Ong, Mariko Siyue Koh, Albert Lim Yick Hou, John A. Abisheganaden, Krasimira Tsaneva-Atanasova, Stephan C. Schuster, Sanjay H. Chotirmall. (2020) Metagenomics Reveals a Core Macrolide Resistome Related to Microbiota in Chronic Respiratory Disease, American Journal of Respiratory and Critical Care Medicine, doi: 10.1164/rccm.201911-2202OC. [Epub ahead of print]
7. Yaqin Song, Chun Yang, Gukui Chen, Yixi Zhang, Zijing Seng, Zhao Cai, Chao Zhang, Liang Yang, Jianhua Gan, and Haihua Liang (2019) Molecular insights into the master regulator CysB mediated bacterial virulence in Pseudomonas aeruginosa. Molecular Micorbiology, doi: 10.1111/mmi.14200
8. Yingying Cheng, Joey Kuok Hoong Yam, Zhao Cai, Yichen Ding, Lian-Hui Zhang, Yinyue
Deng, Liang Yang (2018) Population dynamics and transcriptomic responses of Pseudomonas aeruginosa in a complex laboratory microbial community, npj Biofilms and Microbiomes doi: 10.1038/s41522-018-0076-z
9. Lin Chua S, Liu Y, Li Y, Jun Ting H, Kohli GS, Cai Z, Suwanchaikasem P, Kau Kit Goh K,Pin Ng S, Tolker-Nielsen T, Yang L, Givskov M. (2017) Reduced Intracellular c-di-GMP Content Increases Expression of Quorum Sensing-Regulated Genes in Pseudomonas aeruginosa. Front Cell Infect Microbiol. 2017 Oct;7:451. doi: 10.3389/fcimb.2017.00451
10. Song Lin Chua, Yichen Ding, Yang Liu, Zhao Cai, Jianuan Zhou, Sanjay Swarup, Daniela I.Drautz-Moses, Stephan Christoph Schuster, Staffan Kjelleberg, Michael Givskov and Liang Yang (2016) Reactive oxygen species drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels; Open Biology, 6: 160162
11. Victor Bochuan Wang, Song-Lin Chua, Zhao Cai, Krishnakumar Sivakumar, Qichun Zhang,Staffan Kjelleberg, Bin Cao, Say Chye Joachim Loo, Liang Yang (2014) A stable synergistic microbial consortium for simultaneous azo dye removal and bioelectricity generation; Bioresource Technology, 155 (2014) 71–76
12. Yang-Chun Yong, Zhao Cai, Yang-Yang Yu, Peng Chen , Rongrong Jiang , Bin Cao , Jian-Zhong Sun, Jing-Yuan Wang, Hao Song (2013) Increase of riboflavin biosynthesis underlies enhancement of extracellular electron transfer of Shewanella in alkaline microbial fuel cells; Bioresource Technology, 130 (2013) 763–768
13. Yang-Chun Yong, Jing-Xian Wang, Zhao Cai and Jian-Zhong Sun. (2013) Chapter 5 Quorum sensing for clean environment and green bioenergy. Advances in Environmental Research. Volume 28. pp. 129-148. ISBN: 978-1-62417-738-5.（Book chapter）