16 构树化学成分研究 殷志琦 巢剑非 张雷红 叶文才 沈文斌 赵守训 天然产物研究与开发 2006，（3） 　
17 小紫金牛的化学成分研究 李药兰 苏妙贤 岑颖洲 张晓琦 戴毅 叶文才 中药材 2006，（4） 　
18 繁缕中游离氨基酸的测定 胡永美 叶文才 汪豪 陈重明 汪涛 赵守训 中成药 2006，（5） 　
19 桑叶中水溶性成分的研究 倪 丽 张现涛 殷志琦 汪豪 叶文才 中药材 2006，（2） 　
20 海金沙地上部分的化学成分 张雷红 殷志琦 范春林 叶文才 赵守训 中国天然药物 2006，（2） 　
21 宽叶大戟化学成分的研究 张雷红 张现涛 叶文才 殷志琦 郑丹 赵守训 天然产物研究与开发 2006，（1） 　
22 西藏胡黄连中的环烯醚萜类化学成分 汪 豪 吴佳俊 刘戈 叶文才 赵守训 中国天然药物 2006，（1） 　
23 壳聚糖细胞微囊的结构表征及其功能活性 李晓玲 王欢 栗原博 吕艳青 路晓辉 蔡绍晖 华西药学杂志 2006，（1） 　
24 Evaluation of the Hypolipemic Property of Camellia sinensisVar. ptilophylla on Postprandial Hypertriglyceridemia Kurihara H Shibata H, Fukui Y, Kiso Y, Xu JK, Yao XS, Fukami H J Agric Food Chem. 2006.7， 1254(14):4977-4981 SCI
25 Anti-tumor activities of the antlered form of Ganoderma lucidum in allogeneic and syngeneic tumor-bearing mice Nonaka Y Shibata H, Nakai M, Kurihara H, Ishibashi H, Kiso Y, Tanaka T, Yamaguchi H, Abe S. Biosci Biotechnol Biochem. 2006.9，70(9):2028-2034. SCI
26 Anti-Stress Effect of BRANDS Essence of Chicken (BEC) on Plasma Glucose Levels in Mice Loaded with Restraint Stress Hiroshi kurinara Xin-Sheng Yao,Hajime Nagai, Nobuo Tsuruoka, Hiroshi Shibata,Yoshinobu Kiso,Harukazu Fukami J Health Sci.2006 52 :252-258 SCI
27 The Protective Effect of Brand’s Essence of Chicken (BEC) on Energy Metabolic Disorder in Mice Loaded with Restraint Stress Hiroshi kurinara Xin-Sheng Yao,Hajime Nagai, Nobuo Tsuruoka, Hiroshi Shibata,Harukazu Fukami J Health Sci.2006. 52(1):17-23 SCI
28 Quality evaluation of Ganoderma through simultaneous determination of nine triterpenes and sterols using pressurized liquid extraction and high performance liquid chromatography Zhao J Zhang, Xiao-Qi Li, Shao-Ping Yang, Feng-Qing Wang, Yi-Tao Ye, Wen-Cai J Separation Science 2006.11，29 (17): 2609-2615 SCI
29 Two new eremophilanolides from Xanthium sibiricum Zhang XQ Ye, Wen-Cai Jiang, Ren-Wang YYin, Zhi-Qi Zhao, Shou-Xun Mak, Thomas C. W. Yao, Xin-Sheng Natural Product Research 2006.11，20 (13): 1265-1270 SCI
30 Apoptotic activity of 23 - Hydroxybetulinic acid on Lovo cell line Yan C Wencai, Ye Hiroshi, Kurihara Xinsheng, Yao Acta Pharmacologica Sinica 2006.7，27: 69-69 SCI
31 New Diterpenoids from Andrographis paniculata (Burm. f.) Nees Zhang XQ Wang, Guo-Cai Ye, Wen-Cai Li, Qian Zhou, Guang-Xiong Yao, Xin-Sheng Journal of Integrative Plant Biocogy，2006.9， 48 (9): 1122-1125 SCI
32 Ginsenoside Re attenuate beta-amyloid and serum-free induced neurotoxicity in PC12 cells Ji Z N Dong, T. T. X., Ye, W. C.,Choi, R. C.,Lo, C. K.,Tsim, K. W. K Journa of Ethnopharmacology 2006.8.11，107 (1): 48-52 SCI
33 Biphenyl glycosides from the fruit of Pyracantha fortuneana Dai Yi Zhou, Guang-Xiong,Kurihara, Hiroshi,Ye, Wen-Cai), Yao, Xin-Sheng Journal of Natural Products2006.7.28，69 (7): 1022-1024 SCI
34 Evaluation of the hypolipemic property of Camellia sinensis var. ptilophylla on postprandial hypertriglyceridemia Kurihara H Shibata H, Fukui Y, Kiso Y, Xu JK, Yao XS, Fukami H Journal of Agricultural and food Chemistry 2006.7.12，54 (14): 4977-4981 SCI
35 Anti-stress effect of BRAND'S Essence of Chicken (BEC) on plasma glucose levels in mice loaded with restraint stress Kurihara H Yao XS, Nagai H, Tsuruoka N, Shibata H, Kiso Y, Fukami H Journal of Health Science2006.6， 52 (3): 252-258 SCI
36 The protective effect of BRAND'S Essence of Chicken (BEC) on energy metabolic disorder in mice loaded with restraint stress Kurihara H Yao, XS Nagai ,H Tsuruoka ,N Shibata ,H Kiso, Y Fukami, H Journal of Health Science 2006.2，52 (1): 17-23 SCI
37 Four new cycloartane glycosides from Thalictrum fortunei Zhang XT Zhang, LH Ye, WC Zhang, XL Yin, ZQ Zhao, SX Yao, XS Chemical & Pharmaceutical Bulletin2006.1， 54 (1): 107-110 SCI
38 Cloning and characterizing mutated human stromal cell-derived factor-1 (SDF-1): C-terminal alpha-helix of SDF-1 alpha plays a critical role in CXCR4 activation and signaling, but not in CXCR4 binding affinity Tan Yi Du, Jun, Cai Shaoxi, Li Xiaokun, Ma Weifeng, Guo Zhigang, Chen Hongyuan, Huang Zhifeng, Xiao Jian, Cai, Lu Cai, Shaohui Experimental Hematology2006.11， 34 (11): 1553-1562 SCI
39 藤茶总黄酮对拘束负荷引起小鼠肝损伤的保护作用 郑洁静 续洁琨 江涛 赵亮 贺飞 姚新生 栗原博（通讯） 中国药理学通报2006 .10， 22（10）：1249—1253 ISTP
40 知母总黄铜对溴酸钾诱导小鼠肾损伤的保护作用 江 涛 黄杰昌 郑洁静 赵亮 李满妹 姚新生 栗原博(通讯) 中国药理学通报2006.12 ，22（2）：1517—1523 ISTP
41 Central nervous system activity of purine ikaloids from cammelia assamica var. kucha in mice Xu, Jiekun Yao, Xinsheng ,Zhao, Liang; Hiroshi, Kurihara Acta Pharmacologica Sinica 2006，27 SCI
42 Flavonoids from Lygodium japonicum Zhang, Lei-Hong Yin, Zhi-Qi; Ye, Wen-Cai Biochemical Systematics and ecology 2006，34（12） SCI
43 In vitro antiviral activities of Chinese medicinal herbs against duck hepatitis B virus Leung, K. T Chiu, Lawrence C. M.; Lam, W. S.; Li, Yaolan Sun, Samuel S. M.; Ooi, Vincent E. C. Phytotherapy Research 2006，20（10） SCI
44 Microbial metabolism of methyl protodioscin by Aspergillus niger culture - A new androstenedione producing way from steroid He, Xiangjiu Liu, Bo; Wang, Guanghui; Wang, Xinluan; Su, Lina; Qu, Gexia; Yao, Xinsheng Journal of Steroid Biochemistry and Molecular Biology 2006，100 SCI
45 Antimicrobial activities of cinnamon oil and cinnamaldehyde from the Chinese medicinal herb Cinnamomum cassia Blume Ooi, Linda S. M. Li, Yaolan Kam, Sheung-Lau; Wang, Hua; Wong, Elaine Y. L.; Ooi, Vincent E. C. The American Journal of Chinese Medicine 2006，34（4） SCI
46 Antiviral activity and constituent of Ardisia chinensis Benth against coxsackie B3 virus Su, Miaoxian Li, YL; Leung, KT; Cen, YZ; Li, T; Chen, RZ; Ooi, VEC Phytotherapy Research 2006，20（8） SCI
47 Antiviral flavans from the leaves of Pithecellobium clypearia Li, Yaolan Leung, Kam-Tong; Yao, Fenghe; Ooi, Linda S. M.; Ooi, Vincent E. C. Journal of Natural Products 2006，69（5） SCI
48 Cytotoxic biotransformed products from cinobufagin by Mucor spinosus and Aspergillus niger He XJ Tang JS, Qiao AM, Wang GH, Jiang MM, Liu RH, Yao XS Steroids 2006，71（5） SCI
49 Bioconversion of methyl protodioscin by Penicillium melinii cells He XJ Qiao AM, Liu B, Wang XL, Wang GH, Qu GX, Liu RH, Yao XS Enzyme and Microbial Technology 2006，38 SCI
50 Hiroko Ishibashi,Yoshinobu Kiso,Takaharu Tanaka, Hideyo Yamaguchi, Shigeru Abe. Anti-Tumor Activities of the Antlered Form of Ganoderma lucidum in Allogeneic and Syngeneic Tumor-Bearing Mice Yuji Ninaka Hiroshi Shibata, Masaaki Nakai, Hiroshi Kurihara Biosci.Biotechnol.Biochem.2006.70(9):2028-2034. SCI
51 Constituents from the leaves of Phellodendron amurense and their antioxidant activity Leu CH Li CY , Yao XS, Wu TS Chemical & Pharmaceutical Bulletin2006.9，54 (9): 1308-1311 SCI
52 Iridoids from Neopicrorhiza scrophulariiflora and their hepatoprotective activities in vitro. Wang, Hao Wu, Fei-Hua; Xiong, Fei; Wu, Jia-Jun; Zhang, Lu-Yong; Ye, Wen-Cai; Li, Ping; Zhao, Shou-Xun. Chemical & Pharmaceutical Bulletin 2006, 54(8)：1144-1149 SCI
53 Puqienine F, a novel veratramine alkaloid from the bulbs of Fritillaria puqiensis. Li, Hui-Jun Jiang, Yan; Li, Ping; Ye, Wen-Cai Chemical & Pharmaceutical Bulletin 2006,54(5)：722-724 SCI
54 Ginsenoside Re attenuate beta-amyloid and serum-free induced neurotoxicity in PC12 cells Ji ZN Dong TTX , Ye WC Choi RC , Lo CK , Tsim KWK Journal of Ethnopharmacology 2006 .8.11,107 (1): 48-52 SCI
55 Steroidal saponins from Solanum nigrum Zhou X.-L He X.-J., Wang G.-H., Gao H., Zhou G.-X., Ye W.-C. and Yao X.-S. Journal of Natural Products 2006.69 (8): 1158-1163 SCI
56 Assessment of 3H-23-hydroxybetulinic acid uptake kinetics in human Caco-2 cell lines Yang M, Wang GJ, Zhao FK, Wu XL, Cao GX, Luo SN and Ye WC Acta Pharmacologica Sinica 2006.27: 208-208 Suppl.1. SCI
57 抗氧化能力指数（ORAC)测定原理及应用 续洁琨 姚新生 栗原博 中国药理学通报 2006,8 　
　 　 　 　 　 　
新药研究所：王玉强 张在军 杨兆琪 肖瑛 索绪斌 　
序号 论文名称 第 一作 者 其他作者及排序 发表刊物、发表时间 备注
2006 Synthesis and antitumor activity of CBI-bearing ester and carbamate prodrugs of CC-1065 analogue Wang Yuqiang Li, Lianfa Tian, Zhiming Jiang, Wei Larrick, James W. Bioorganic & Medicinal Chemistry 2006.12.1，14 (23): 7854-7861 SCI
2 Synthesis and preliminary antitumor activity evaluation of a DHA and doxorubicin conjugate Wang YQ Li, LF Jiang, W Yang, ZQ Zhang, ZJ Bioorganic & Medicinal Chemistry Letters2006.7.1， 16 (11): 2974-2977 SCI
3 Synthesis and in vitro biological activity evaluation of the derivatives of Combretastatin A-4. Yang Z 　 Lett. Drug Des. Discovery, 2006, 3(8)： 544-546 SCI
4 Synthesis of 1-benzyl-3-chloro-4-(3,4,5-trimethoxyphenyl) azetidin-2-one. Yang Z Sun, P. Molbank(分子银行) 2006, M513 　
5 Compare of three way of synthesis of simple Schiff base. Yang Z Sun, P. Molbank（分子银行）2006, M514 　
6 抗癌药Combretastatin-4结构修饰的研究进展. 杨兆琪 　 化学通报 2006. 69(8), w80. 　
7 β-偕二甲基环丙烷氨基酸酯的合成. 杨兆琪 苏江涛. 化学试剂 2006. 28(6)： 375-376 　
8 Microwave-Assisted Rapid Synthesis of Intermediate of Ezetimibe. Yang Z 　 Chemical Journal on Internet, 2006. 8(5)： 37. 　
9 河虾中主要过敏原鉴定及分离纯化 张在军 向军俭 广东医学2006.27 (5): 650-651 　
10 NF-κB 与癌症发生的关系研究进展 张在军 王玉强 广东医学2006.27 (7): 180-182