导航
个人简介
学习经历
工作经历
研究方向
主要论文
主要著作
承担课题
个人信息
姓名： 蓝平
部门： 药学院
直属机构： 药学系
性别： 男
--> 职务： 先进与应用化学合成研究院副院长
职称： 副研究员
学位： 博士
毕业院校： 澳大利亚国立大学
联系电话：
电子邮箱： ping.lan@jnu.edu.cn
办公地址： 药学院312
通讯地址： 广州市天河区黄埔大道西601号
邮编： 510632
传真：
荣誉奖励：
联系方式
个人简介
蓝平，博士，副研究员，硕士生导师。现任暨南大学先进与应用化学合成研究院副院长。主要研究方向为有机合成化学：包括天然产物全合成以及新型功能配料的研发与制备。目前主持科研项目包括国家自然科学基金青年项目1项，教育部海外名师项目1项，广东省自然科学基金面上项目1项，中央高校科研培育与创新基金1项，广州市企业横向项目3项。截止2019年9月，共发表SCI收录论文52篇，英文专著2篇，其中第一作者/通讯作者论文28篇，主要发表在Organic Letters, Journal of Organic Chemistry, Journal of Natural Products（天然产物全合成研究成果）和Journal of Colloid and Interface Science, Journal of Agricultural and Food Chemistry（功能配料研究成果）等专业TOP期刊上。
学习经历
2011.10-2015.01 澳大利亚国立大学化学研究院哲学（有机化学）博士
导师：Martin G. Banwell教授（澳大利亚科学院院士）
研究方向为天然产物全合成
2008.09-2011.06 暨南大学药学院医学硕士（药物化学专业）
导师：陈卫民教授
研究方向为天然产物的结构修饰
2004.09-2008.06中南民族大学生命科学学院理学学士（药学专业）
工作经历
2019.09至今暨南大学药学院副高（绿色通道）
2018.11至今暨南大学先进与应用化学合成研究院副院长
2016.12-2019.07 暨南大学理工学院食品科学与工程系 副高（绿色通道）
2015.10-2016.12 澳大利亚沃尔特伊丽莎医学研究所（The Walter and Eliza Hall Institute of Medical Research）博士后研究员
合作导师：Peter M. Colman教授（澳大利亚科学院院士）
Guillaume Lessene 副教授及Peter Czabotar副教授
研究方向为化学生物学
2015.02-2015.10澳大利亚国立大学化学研究院 博士后研究员
合作导师：Lewis N. Mander教授（澳大利亚科学院院士）
研究方向为天然产物全合成
研究方向
主要论文
53.
Lan, P.; Ye, S.; Banwell, M. G.* The application of dioxygenase-based chemoenzymatic processes to the total synthesis of natural products. Chem. Asian J.published online DOI: 10.1002/asia.
影响因子（3.698）引用次数（0）
52.
Li, X.; Hai, Y. W.; Ma, D.; Chen, J.; Banwell, M. G.; Lan, P.*Fatty acid ester surfactants derived from raffinose: synthesis, characterization and structure-property profiles. J. Colloid Interf. Sci. 2019, 556, 616–627.
影响因子（6.361）引用次数（0）A1二区
51.
Chen, Y.; Chen, W. N.; Hu, N.; Banwell, M. G.; Ma, C.;Gardiner, M.; Lan, P.* Anticarcinogenic and anti-inflammatory properties of apigenin-derived isolaxifolin. J. Nat. Prod. 2019, 82, 2451–2459.
影响因子（4.257）引用次数（0）A1二区
50.
Sheng, B.; Vo, Y.; Lan, P.; Gardiner M. G.; Banwell, M. G.*, Sun, P.* The direct and metal-catalyzed photochemical dimerization of the phthalide (Z)-ligustilide leading to both [2+2] and [4+2] cycloadducts: application to total syntheses of tokinolides A-C and riligustilide. Org. Lett. 2019, 21, 6295–6299.
影响因子（6.555）引用次数（0）A1一区
49.
Lan, P.; Banwell, M. G.*; Willis, A. C. Application of electrocyclic ring-opening and desymmetrizing nucleophilic trappings of meso-6,6-dibromobicyclo[3.1.0]hexanes to total syntheses of crinine and haemanthamine alkaloids. J. Org. Chem. 2019, 84, 3431–3466.
影响因子（4.849）引用次数（0）A1二区
48.
Zhang, Z.; Liu, Y.; Chen, Y.*; Li, L.; Lan, P.; He, D.; Song, J.*; Zhang, Y.* Transdermal delivery of 5-aminolevulinic acid by nanoethosome gels for photodynamic therapy of hypertrophic scars. ACS Appl. Mater. Inter. 2019, 11, 3704–3714.
影响因子（8.097）引用次数（0）A1一区
47.
Mikusek, J.; Nugent, J.; Lan, P.; Banwell, M. G.* A chemical synthesis study establishes the true structure of the potent anti-inflammatory agent myrsinoic acid F. J. Nat. Prod. 2019, 82, 96–100.
影响因子（4.257）引用次数（0）A1二区
46.
Benoit, B.; Tang, F.; Lan, P., Willis, A. C.; Banwell, M. G.* Synthetic studies on the marine-derived sesquiterpene (+)-viridianol: divergent behaviour of two structurally related, ring-fused cyclopropanes under the same hydrogenolytic conditions. Aust. J. Chem.2019, 72, 305–310.
影响因子（1.558）引用次数（0）A2四区
45.
Lan, P.; Banwell, M. G.* Diastereoselective alkylation, allylation and benzylation reactions (of derived amides). Encyclopedia of Reagents for Organic Synthesis (e-EROS) 2019, In press
著作章节
44.
Tang, F.; Lan, P.; Benoit, B.; Banwell, M. G.*; Willis, A. C. Total synthesis of (+)-viridianol, a marine-derived sesquiterpene embodying the decahydrocyclobuta[d]indeneframework. J. Org. Chem. 2018, 83, 14049–14056.
影响因子（4.849）引用次数（3）A1二区
43.
Yao, N.; Wang, C.; Hu, N.; Li, Y.; Liu, M.; Lei, Y.; Chen, M.; Chen, L.; Chen, C.; Lan, P.; Chen, W. M.; Chen, Z.; Fu, D.; Ye, W. C.; Zhang, D. M.* Inhibition of PINK1/Parkin-dependent mitophagy sensitizes ultidrug-resistant cancer cells to B5G1, a new betulinic acid analog. CellDeath Dis. 2019, 10, 232.
影响因子（5.638）引用次数（0）A1二区
42.
Liang, M. Y.; Banwell, M. G.; Wang, Y.*; Lan, P.*Effect of variations in the fatty acid residue of lactose monoesters on their emulsifying properties and biological activities. J. Agric. Food Chem. 2018, 66, 12594–12603.
影响因子（3.412）引用次数（1）A1一区
41.
Qiu, Y.; Dlugosch, M.; Liu, X.; Khan, F.; Ward, J. S.; Lan, P.; Banwell, M. G.* The reductive cyclisation of o-nitroarylated-α,β-unsaturated aldehydes and ketones with TiCl3/HCl or Fe/HCl leading to 1,2,3,9-tetrahydro-4H-carbazol-4-ones and related heterocycles. J. Org. Chem.2018, 83, 12023–12033.
影响因子（4.849）引用次数（0）A1二区
40.
Moujalled, D.; Pomilio, G.; Ghiurau, C.; Ivery, A.; Salmon, J.; Rijal, S.; Macraild, S.; Zhang, L.; Teh, T. C.; Tiong, I. S.; Lan, P.; Chanrion, M.; Claperon, A.; Rocchetti, F.; Zichi, A.; Kraus-Berthier, L.; Wang, Y.; Halilovic, E.; Morris, E.; Colland, F.; Segal, D.; Huang, D.; Roberts, A. W.; Maragno, A. L.; Lessene, G.; Geneste, O.; Wei. A.* Combining BH3-Mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia. Leukemia2019, 33, 905–917.
影响因子（13.164）引用次数（12）A1一区
39.
Ma, Y. R.; Banwell, M. G.; Yan, R.*; Lan, P.*Comparative study of the emulsifying properties of a homologous series of long-chain 6?-O-acylmaltose esters. J. Agric. Food Chem. 2018, 66, 8832–8840.
影响因子（3.412）引用次数（1）A1一区
38.
Lan, P.; Banwell, M. G.*; Willis, A. C. Total synthesis of (±)-crinane from 6,6-dibromobicyclo[3.1.0]hexane and using a 5-exo-trigradical cyclisation reaction to assemble the requisite C3a-arylated perhydroindole. J. Org. Chem. 2018, 83, 8493–8498.
影响因子（4.849）引用次数（2）A1二区
37.
Bon, D. J.-Y. D.; Mander, L. N.*; Lan, P.*Syntheses of gibberellins A15and A24, the key metabolites in gibberellin biosynthesis. J. Org. Chem. 2018,83, 6566–6572.
影响因子（4.849）引用次数（0）A1二区
36.
Xiang, L.; Chen, J.; Yang, Y.; Xie, D.; Li, Y.; Liu, F.; Ma, H.; Wu, F.; Chen, K.;* Wu, H.; Lan, P.; Yuan, G.; Li, S.; Wang, Y.; Liu, J.; Zhu, J. Enhanced high permittivity and lowed dielectric loss in cellulose-fibre framework polymer microcomposites. Polym. Composite.2019, 40, 1526–1535.
影响因子（2.324）引用次数（0）A2三区
35.
Liang, M. Y.; Chen, Y.; Banwell, M. G.; Wang, Y.*; Lan, P.*Enzymatic preparation of a homologous series of long-chain 6-O-acylglucose esters and their evaluation as emulsifiers. J. Agric. Food Chem. 2018, 66, 3949–3956.
影响因子（3.412）引用次数（3）A1一区
34.
Chen, Y.; Lan, P.* Total Syntheses and biological evaluation of the Ganoderma lucidum alkaloids lucidimines B and C. ACS Omega 2018,3,3471–3481.
影响因子（2.584）引用次数（1）新期刊，暂无分区
33.
Lan, P.*; Herlt, A. J.; Willis, A. C.; Taylor, W. C.; Mander, L. N.* Structures of New Alkaloids from rain forest treesGalbulimima belgraveanaand Galbulimima baccatain Papua New Guinea, Indonesia and Northern Australia. ACS Omega 2018, 3, 1912–1921.
影响因子（2.584）引用次数（1）新期刊，暂无分区
32.
Taher, E. S.; Banwell, M. G.*; Buckler, J. N.; Yan, Q.; Lan, P. The exploitation of enzymatically-derived cis-1,2-dihydrocatechols and related compounds in the synthesis of biologically active natural products. Chem. Rec. 2018, 18, 239–264.
影响因子（3.855）引用次数（9）A1二区
31.
Jian, J.; Fan, J.; Yang, H.;Lan, P.; Li, M.; Liu, P.; Gao, H.*; Sun, P. H.* Total synthesisof the flavonoidnatural product Houttuynoid Afromhouttuynia cordata. J. Nat. Prod. 2018, 81, 371–377.
影响因子（3.798）引用次数（2）A1二区
30.
Zhao, Q.; Zou, Y.; Huang, C.; Lan, P.; Zheng, J.; Ou, S.* Formation of a hydroxymethylfurfural-cysteine adduct and its absorption and cytotoxicity in Caco-2 cells. J. Agric. Food Chem. 2017, 65, 9902–9908.
影响因子（3.412）引用次数（4）A1一区
29.
Brouwer, J. M.; Lan, P.; Cowan, A. D.; Bernardini, J. P.; Birkinshaw, R. W.; van Delft, M. F.; Sleebs, B. E.; Robin, A. Y.; Wardad, A.; Tan, I. K.; Reljic, B.; Lee, E. F.; Fairlie, W. D.; Call, M. J.; Smith, B. J.; Dewson, G.; Lessene, G.; Colman, P. M.; Czabotar, P. E.* Conversion of Bim-BH3 from activator to inhibitor of Bak through structure-based design. Mol. Cell 2017,68, 659–672.
影响因子（14.713）引用次数（6）A1一区
28.
Banwell, M. G.; Bolte, B.; Buckler, J. N.; Chang, E. L.; Lan, P.; Taher, E. S.; White, L. V.; Willis, A. C. Chemoenzymatic pathways for the synthesis of biologically active natural products. Journal and Proceedings of the Royal Society of New South Wales 2016, 149, 34–50.
影响因子（1.124）引用次数（9）A2四区
27.
Chang, E. L.; Benoit, B.; Lan, P.; Willis, A. C.; Banwell, M. G.* Chemoenzymatic total syntheses of the enantiomers of the protoilludanes 8-deoxydihydrotsugicoline and radudiol. J. Org. Chem. 2016, 81, 2078–2086.
影响因子（4.849）引用次数（12）A1二区
26.
Lan, P.; White, L. E.;Taher, E. S.;Guest, P. E.; Banwell, M. G.*; Willis, A. C. Chemoenzymatic synthesis of (+)-asperpentyn and the enantiomer of the structure assigned to aspergillusol A. J. Nat. Prod.2015, 78, 1963–1968.
影响因子（3.798）引用次数（12）A1二区
25.
Lan, P.; Banwell, M. G.*; Willis, A. C. Chemoenzymatic synthesis of the enantiomer of 4,12-dihydroxysterpurene, the structure assigned to a metabolite isolated from the culture broth of Stereum purpureum.Org. Lett. 2015, 17, 166–169.
影响因子（6.579）引用次数（12）A1一区
24.
Crisp, A. L.; Li, J.; Lan, P.; Nugent, J.; Matousova, E.; Banwell, M. G.* The Palladium-catalysed intramolecular Alder-ene (IMAE) reactions of certain heteroatom-linked 1,6-enynes: the formation of hexahydro-indoles and –benzofurans. Aust. J. Chem.2 015, 68, 1183–1189.
影响因子（1.558）引用次数（8）A2四区
23.
White, L. V.; Lan, P.; Schwartz, B. D.; Willis, A. C.; Banwell, M. G.* New, homochiral synthons obtained through simple manipulations of enzymatically-derived 3-halo-cis-1,2-dihydrocatechols. Aust. J. Chem. 2015, 68, 1467–1471.
影响因子（1.558）引用次数（5）A2四区
22.
Banwell, M. G.*; Buckler, J.; Jackson, C. J.; Lan, P.; Ma, X.; Matousova, E.; Nugent, J. Devising new syntheses of the alkaloid galanthamine, a potent and clinically deployed inhibitor of acetylcholine esterase. Strategies and Tactics in Organic Synthesis 2015, 11, 29–50.
著作章节，引用次数（3）
21.
Yao, N.; Li, Y. J.; Zhang, D. M.; Liu, D. L.; Tang, M. K.; Yiu, A.; Li, Y.; Chen, W. M.; Lan, P.; Yao, Z.; Chen, Z. S.; Ye, W. C.* B4G2 induces mitochondrial apoptosis by the ROS-mediated opening of Ca2+-dependent permeability transition pores. Cell. Physiol. Biochem. 2015, 37, 838–852.
影响因子（2.875）引用次数（9）A1二区
20.
Lan, P.;Jackson,C. J.;Banwell, M. G.*; Willis, A. C. Synthesis of a D-ring isomer of galanthamine viaa radical-based Smiles rearrangement reaction. J. Org. Chem. 2014, 79, 6759–6764.
影响因子（4.849）引用次数（15）A1二区
19.
Lan, P.; Banwell, M. G.*; Willis, A. C. Chemoenzymatic total syntheses of ribisins A, B and D, polyoxygenated benzofuran derivatives displaying NGF-potentiating properties. J. Org. Chem.2014, 79, 2829–2842.?被选为重点推荐论文
影响因子（4.849）引用次数（26）A1二区
18.
Lan, P.; Banwell, M. G.*; Ward, J. S.; Willis, A. C. Chemoenzymatic total synthesis and reassignment of the absolute configuration of ribisin C. Org. Lett. 2014, 16, 228–231.
影响因子（6.579）引用次数（9）A1一区
17.
Zhang, D. M.; Li, Y. J.; Shu, C.; Ruan, Z. X.; Chen, W. M.; Yiu, A.; Peng, Y. H; Wang, J.; Lan, P.; Yao, Z.; Fung, K. P.; Fu, L. W.; Chen, Z. S.*; Ye, W. C.* Bipiperidinyl derivatives of 23-hydroxybetulinic acid reverse resistance of HepG2/ADM and MCF-7/ADR cells. Anti-Cancer Drugs 2013, 24, 441–454.
影响因子（1.784）引用次数（8）A2三区
16.
Lan, P.;Wu, Z. W.; Chen, W. N.; Sun, P. H.; Chen, W. M.* Molecular modeling studies on phosphonic acid-containing thiazole derivatives: design for fructose-1,6-bisphosphatase inhibitors. J. Mol. Model.2012, 18, 973–990.
影响因子（1.736）引用次数（3）A2四区
15.
Zhang, D. M.; Shu, C.; Chen, J. J.; Sodani, K.; Wang, J.; Bhatnagar, J.; Lan, P.; Ruan, Z. X.; Xiao, Z. J.; Ambudkar, S. V.; Chen, W. M.; Chen, Z. S.*; Ye, W. C.* BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistance in vitroand in vivo. Mol. Pharmaceut.2012, 9, 3147–3159.
影响因子（4.384）引用次数（39）A1二区
14.
Lan, P.;Wang, J.; Zhang, D. M.; Shu, C.; Cao, H. H.; Sun, P. H.; Wu, X. M.; Ye, W. C.*; Chen, W. M.* Synthesis andantiproliferative evaluation of 23-hydroxybetulinic acid derivatives. Eur. J. Med. Chem.2011, 46, 2490–2502.
影响因子（4.816）引用次数（24）A1二区
13.
Lan, P.;Chen, W. N.; Chen, W. M.* Molecular modeling studies on imidazo[4,5-b]pyridine derivatives as Aurora A kinase inhibitors using 3D-QSAR and docking approaches. Eur. J. Med. Chem. 2011, 46, 77–94.影响因子（4.816）引用次数（38）A1二区
12.
Lan, P.;Chen, W. N.; Huang, Z. J.; Sun, P. H.; Chen, W. M.* Understanding the structure-activity relationship of betulinic acid derivatives as anti-HIV-1 agents by using 3D-QSAR and docking. J. Mol. Model.2011, 17, 1643–1659.
影响因子（1.736）引用次数（17）A2四区
11.
Lan, P.;Sun, J. R.; Chen, W. N.; Sun, P. H.; Chen, W. M.* Molecular modeling studies on d-annulated benzazepinones as VEGF-R2 kinase inhibitors using docking and 3D-QSAR. J. Enzym. Inhib. Med. Chem.2011, 26, 367–377.
影响因子（3.638）引用次数（8）A1二区
10.
Lan, P.;Chen, W. N.; Sun, P. H.; Chen, W. M.* 3D-QSAR and molecular docking studies of azaindole derivatives as Aurora B kinase inhibitors. J. Mol. Model.2011, 17, 1191–1205.
影响因子（1.736）引用次数（11）A2四区
9.
Lan, P.;Chen, W. N.; Sun, P. H.; Chen, W. M.* 3D-QSAR studies on betulinic acid and betulin derivatives as anti-HIV-1 agents using CoMFA and CoMSIA. Med. Chem. Res.2011, 20,1247–1259.
影响因子（1.402）引用次数（4）A2四区
8.
Sun, J. R.; Lan, P.; Sun, P. H.; Chen, W. M.* 3D-QSAR and docking studies on pyrrolopyrimidine derivatives as LIM-Kinase 2 inhibitors. Lett. Drug Des. Discov.2011, 8, 229–240.
影响因子（1.170）引用次数（8）A2四区
7.
Huang, Z. J.; Zeng, Y.; Lan, P.; Sun, P. H.; Chen, W. M.* Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine. Mini-Rev. Med. Chem.2011, 11, 1122–1129.
影响因子（2.645）引用次数（45）A2三区
6.
Song, Q. L.; Guo, B. Q.; Zhang, W.; Lan, P.;Sun, P. H.; Chen, W. M.* Design, synthesis and antibacterial activity of novel ketolides bearing an aryltetrazolyl-substituted alkyl side chain. J. Antibiot.2011, 64, 571–581.
影响因子（2.150）引用次数（6）A2三区
5.
Wu, X.; Lan, P.; Liu, Z.; Ruan, Z. X.; Wang, H.; Wang, G. C.; Ye, W. C.; Li, Y. L. 3D-QSAR studies of natural steroidal saponins as anticancer agents in human nasopharyngeal carcinoma epithelial cells. Lett. Drug Des. Discov.2013, 10, 245–252.
影响因子（1.170）引用次数（1）A2四区
4.
Lan, P.;Xie, M. Q.; Yao, Y. M.; Chen, W. N.; Chen, W. M.* 3D-QSAR studies and molecular docking on [5-(4-Amino-1H-benzoimidazol-2-yl)-furan-2-yl]-phosphonic acid derivatives as fructose-1, 6-biphophatase inhibitors. J. Comput. Aided Mol. Des.2010, 24, 993–1008.
影响因子（2.990）引用次数（11）A2三区
3.
Lan, P.;Chen, W. N.; Xiao, G. K.; Sun, P. H.; Chen, W. M.* 3D-QSAR and docking studies on pyrazolo[4,3-h]quinazoline-3-carboxamides as cyclin-dependent kinase 2 (CDK2) inhibitors. Bioorg. Med. Chem. Lett.2010, 20, 6764–6772.
影响因子（2.420）引用次数（36）A2三区
2.
Lan, P.;Huang, Z. J.; Sun, J. R.; Chen, W. M.* 3D-QSAR and molecular docking studies on fused pyrazoles as p38α mitogen-activated protein kinase inhibitors. Int. J. Mol. Sci.2010, 11, 3357–3374.
影响因子（2.862）引用次数（27）A2三区
1.
Hu, L.; Lan, P.;Song, Q. L.; Huang, Z. J.; Sun, P. H.; Zhuo, C.; Wang, Y.; Xiao, S.; Chen, W. M.* Synthesis and antibacterial activity of C-12 pyrazolinyl spiro ketolides. Eur. J. Med. Chem.2010, 45, 5943–5949.
影响因子（3.447）引用次数（12）A1二区
主要著作
承担课题
7.
基于稠环偕二卤代环丙烷开环反应的活性天然产物全合成研究，广东省自然科学基金面上项目，2019-2022，10万，主持，编号：2019A
6.
TBHQ的新型合成工艺研究，横向课题，广东广业清怡食品科技有限公司，2019-2021，30万，主持
5.
基于稠环偕二卤代环丙烷不对称开环反应的天然产物全合成研究，国家自然科学基金（青年项目），2019-2021，25万，主持，编号：**
4.
“功能性食品配料绿色合成研究”，教育部海外名师项目，2018-2023，100万，主持，编号：2018-HWMS001
3.
Fissitungfine A的全合成与抗增殖活性研究，科研培育与创新基金，2017-2020，15万，主持，编号：**
2.
高纯度蔗糖脂肪酸单酯绿色制备研究，横向课题，广州嘉德乐生化科技有限公司，2018-2021，10万，主持
1.
山苍子精油绿色萃取及综合利用技术开发与产业化示范，广东省“扬帆计划”引进创新创业团队，2017-2022，300万，参与
发明专利
3.
蓝平，海耀文，李璇。6-O-酰基棉子糖单酯及其合成方法。中国专利申请：8.0，2019-06-17.（已受理）
2.
蓝平，汪勇，滕英来，杜木香. 提高木酚素油溶性的改性方法[P]. 中国专利申请：7.9, 2019-06-24. （已受理）
1.
叶文才，陈卫民，蓝平，张冬梅，王娇，舒畅，曹惠惠，于淼。23-羟基白桦酸衍生物及其制备方法和用途。中国发明专利(公开号CNA)
