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个人简介
学习经历
工作经历
研究方向
主要论文
主要著作
承担课题
个人信息
姓名： 林蒋海
部门： 生命科学技术学院
直属机构： 生化与分子生物学系（生命与健康工程研究院）
性别： 男
--> 职务：
职称： 副研究员
学位： 博士
毕业院校： 牛津大学
联系电话： （020）**
电子邮箱： jianghai.lin@jnu.edu.cn
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个人简介
林蒋海副研究员于毕业于英国牛津大学，专业方向为遗传学。曾从事人类遗传疾病相关基因的基因组相关性及致病基因定位筛选研究。目前为暨南大学生命科学技术学院生化系分子生物研究中心副研究员。主要的研究方向为木质纤维素的综合开发利用以及微生物功能基因组研究。采用基因工程、代谢工程以及合成生物学的手段，通过改变酿酒酵母等真核和原核微生物的代谢途径，引入外源功能酶基因，对蔗渣、秸秆等木质纤维素进行能源化开发等综合利用。在功能基因组方面，主要通过宏基因组以及高通量测序等手段，从特殊环境筛选纤维素酶基因，以及通过转录组研究特定微生物（如黑曲霉、里氏木霉等）在不同培养条件下，基因表达的差异变化，以寻找特定酶组合与底物直接的关系,研究纤维素酶的协同作用关系。
学习经历
博士：2004-2008，University of Oxford 英国
硕士：1999-2002，生化与分子生物学，中山大学
学士：1995-1999，生物化学，中山大学
工作经历
2011.6-至今暨南大学生命科学技术学院生化与分子生物学系（生命与健康工程研究院），副研究员
2008.6-2011.6英国牛津大学Wellcome Trust Centre for Human Genetics,博士后
研究方向
主要论文
1. Fan Z#, Lin J#, Wu J, Zhang L, Lyu X, Xiao W, Gong Y, Xu Y, Liu Z. Vacuum-assisted black liquor-recycling enhances the sugar yield of sugarcane bagasse and decreases water and alkali consumption. Bioresource Technology 2020,309:123349.
2. Shi T#, Lin J#, Li J, Zhang Y, Jiang C, Lv X, Fan Z, Xiao W, Xu Y, Liu Z. Pre-treatment of sugarcane bagasse with aqueous ammonia-glycerol mixtures to enhance enzymatic saccharification and recovery of ammonia. Bioresour Technol 2019,289:121628.
3.Lv X#, Lin J#, Luo L, Zhang D, Lei S, Xiao W, Xu Y, Gong Y, Liu Z. Enhanced enzymatic saccharification of sugarcane bagasse pretreated by sodium methoxide with glycerol. Bioresource Technology 2018, 249:226-233.
4.Lv X, Xiong C, Li S, Chen X, Xiao W, Zhang D, Li J, Gong Y, Lin J, Liu Z. Vacuum-assisted alkaline pretreatment as an innovative approach for enhancing fermentable sugar yield and decreasing inhibitor production of sugarcane bagasse. Bioresour Technol 2017, 239:402-411.
5.Li J, Zhou P, Lv X, Xiao W, Gong Y, Lin J*, Liu Z*. Use of Sugarcane Bagasse with Different Particle Sizes to Determine the Relationship between Physical Properties and Enzymatic Hydrolysis. BioResources 2016, 11:4745-4757.
6.Huang Q, Yan Q, Fu J, Lv X, Xiong C, Lin J*, Liu Z*. Comparative study of different alcoholate pretreatments for enhanced enzymatic hydrolysis of sugarcane bagasse. Bioresource Technology 2016, 211:464-471.
7.Gong Y, Zhang C, Yan Q, He W, Xiao W, Lin J*, Liu Z*. Enhanced enzymatic hydrolysis of sugarcane bagasse hemicellulose using recombinant glucose oxidase expressed by Pichia pastoris. Industrial Crops and Products 2015, 77:458-466.
8.Li J, Zhou P, Liu H, Xiong C,Lin J, Xiao W, Gong Y, Liu Z. Synergism of cellulase, xylanase, and pectinase on hydrolyzing sugarcane bagasse resulting from different pretreatment technologies. Bioresource Technology 2014, 155:258-265.
9.Li J, Zhou P, Liu H, Wu K, Xiao W, Gong Y, Lin J, Liu Z. Ethanol production from xylan-removed sugarcane bagasse using low loading of commercial cellulase. Bioresour Technol 2014, 163:390-394.
10.Li J, Zhou P, Liu H, Wu K, Kang X, Gong Y, Xiao W, Lin J, Liu Z. A comparison of fermentation strategies for cellulosic ethanol production from NaOH-soaked sugarcane bagasse at high solid loading with decreased cellulase loading. Industrial Crops and Products 2014, 62:446-452.
11.Li J, Zhou P, Liu H, Lin J, Gong Y, Xiao W, Liu Z. Monosaccharides and Ethanol Production from Superfine Ground Sugarcane Bagasse Using Enzyme Cocktail. BioResources 2014, 9:2529-2540.
12.Li J, Wu K, Xiao W, Zhang J, Lin J, Gong Y, Liu Z. Effect of antioxidant extraction on the enzymatic hydrolysis and bioethanol production of the extracted steam-exploded sugarcane bagasse. Biochem Eng J 2014, 82:91-96.
13.Li J, Lin J, Zhou P, Wu K, Liu H, Xiong C, Gong Y, Xiao W, Liu Z. One-pot simultaneous saccharification and fermentation: A preliminary study of a novel configuration for cellulosic ethanol production. Bioresour Technol 2014, 161:171-178.
14.Gong Y, Tang G, Wang M, Li J, Xiao W, Lin J, Liu Z. Direct fermentation of amorphous cellulose to ethanol by engineered Saccharomyces cerevisiae coexpressing Trichoderma viride EG3 and BGL1. The Journal of General and Applied Microbiology 2014, 60:198-206.
15.Li J,Lin J, Xiao W, Gong Y, Wang M, Zhou P, Liu Z. Solvent extraction of antioxidants from steam exploded sugarcane bagasse and enzymatic convertibility of the solid fraction. Bioresour Technol 2013, 130:8-15.
16.Xiao W, Liu Z, Lin J, Li J, Wu K, Ma Y, Gong Y, Liu Z. Polymorphisms in TLR1, TLR6 and TLR10 genes and the risk of Graves’ disease. Autoimmunity 2015, 48:13-18.
17.Xiao W, Liu Z, Lin J, Xiong C, Li J, Wu K, Ma Y, Gong Y, Liu Z. Association of TLR4 and TLR5 gene polymorphisms with Graves' disease in Chinese Cantonese population. Hum Immunol 2014, 75:609-613.
18.Xiao W, Liu Z, Lin J, Li J, Wu K, Ma Y, Xiong C, Gong Y, Liu Z. Association of Toll-like receptor 7 and 8 gene polymorphisms with Graves' disease in Chinese Cantonese population. Tissue Antigens 2015, 85:29-34.
19.Painter JN, Anderson CA, Nyholt DR, Macgregor S, Lin J, Lee SH, Lambert A, Zhao ZZ, Roseman F, Guo Q, Gordon SD, Wallace L, Henders AK, Visscher PM, Kraft P, Martin NG, Morris AP, Treloar SA, Kennedy SH, Missmer SA, Montgomery GW, Zondervan KT. Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis. Nat Genet 2011, 43:51-54.
20.Lin J, Zong L, Kennedy SH, Zondervan KT. Coding regions of INHBA, SFRP4 and HOXA10 are not implicated in familial endometriosis linked to chromosome 7p13-15. Mol Hum Reprod 2011, 17:605-611.
21.Lin J, Kennedy SH, Svarovsky T, Rogers J, Kemnitz JW, Xu A, Zondervan KT. High-quality genomic DNA extraction from formalin-fixed and paraffin-embedded samples deparaffinized using mineral oil. Anal Biochem 2009, 395:265-267.
22.Zondervan KT, Treloar SA, Lin J, Weeks DE, Nyholt DR, Mangion J, Mackay IJ, Cardon LR, Martin NG, Kennedy SH, Montgomery GW. Significant evidence of one or more susceptibility loci for endometriosis with near-Mendelian inheritance on chromosome 7p13-15. Hum Reprod 2007, 22:717-728.
主要著作
承担课题
1.广东省科技计划项目，2015A，原位同步糖化发酵蔗渣产乙醇的关键技术研究，2016/01-2017/12，30万元，主持
2.暨南大学科研培育与创新基金研究项目,**,利用全基因组改组技术构建降解纤维素发酵乙醇的运动发酵单胞菌,2014/01-2015/12，8万元，参加
3.广东省科技计划项目农业攻关项目，2012B，蔗渣低碳转化与综合利用关键技术研发，2012/01-2013/12，8万元，参加
