1996年6月四川大学化学系物理化学专业博士研究生毕业。工作经历:
1996年至2003年9月在福州大学化学系工作,2001年7月破格晋升教授,2003年5月获得博士导师资格。2003年10月调入暨南大学化学系工作。讲授本科生《 结构化学 》,硕士研究生《 群论 》、《 量子化学 》、《计算化学》和《计算机辅助药物分子设计》,博士研究生《药物与靶分子的相互识别与作用机制》、《量子药物化学》等课程.研究方向:
金属抗癌药物与靶分子的相互作用机制和药物分子设计研究;生物大分子的结构与功能关系研究;理论化学和计算化学研究.在《J. Phys. Chem. B》,《 Chem. Phys. Lett. 》,《 Theor. Chem. Acc.》,《 J. Mol. Struct.(Theochem) 》,《 Int. J. Quantum Chem. 》,《 Chin. J. Chem. 》, 《化学学报》, 《高等学校化学学报》等期刊发表论文80多篇(被SCI收录70多篇).获省部级三等奖1项(第一完成人). 发表论文被国内外同行在 Chem. Rev.,J. Am. Chem.Soc., J.Org.Chem.,J.Phys. Chem.,Chem.-Eur.J.;J. Chem. Phys. 等著名期刊他引100多次。现主持国家自然科学基金项目1项(20971056),作为学术骨干参加973项目1项。主要论文:
1. Lixin Zhou. Theoretical Analysis on the Transition State of the Anticancer Drug trans-[PtCl2(isopropylamine)2] and Its cis Isomer Binding to DNA Purine Bases. J. Phys. Chem. B, 2009, 113:2110~2127.(2008 IF= 4.189, Top)
2. Yan Gao, Lixin Zhou*.DNA Bindings of a Novel Anticancer Drugtrans-[PtCl2 (isopropylamine)(3-picoline)] and Kinetic Competition of Purine Bases with Protein Residues in the Bifunctional Substitutions, a Theoretical DFT Study. Theor. Chem. Acc., 2009, 123:455~468. (2008 IF=2.37)
3. Yaying Zhao, Lixin Zhou*. Computational study of Hydrogen-Bonded Complexes between the Most Stable Tautomers of L-Leucine and bases of RNA. Theor. Chem. Acc., 2005, 113: 249~256. (IF=2.209)
4. Yaying Zhao, Lixin Zhou*.Computational study of hydrogen-bonded complexes of the pyrimidinic bases of RNA and L-leucine. J. Mol. Struct.(Theochem), 2005, 726:31~37.(IF=1.007)
5. Qinghui Yuan , Lixin Zhou* , Yan Gao.The Hydrolysis Mechanism of the Anticancer Agent trans-Dichloro(ammine)(quinoline)platinum Complex: A Theoretical Study. J. Theor. Comput. Chem. 2008, 7,381~395. (IF=1.009)
6. Lixin Zhou. Ab initio and density functional predictions of the structure, gas-phase acidity and aromaticity of 1,2-dithio-3,4-diselenosquaric acid. Chem. Phys. Lett., 2000,317, 330~337. (IF=2.269 )
7. Lixin Zhou, Chaoyong Mang, Yongfan Zhang, Shengchang Xiang, Zunxing Huang. Theoretical predictions of the structure, gas-phase acidity and aromaticity of tetrathiosquaric acid. Int. J. Quantum Chem., 2000, 78,443~449. (IF=1.318 )
8. Lixin Zhou. Theoretical predictions on the structure, gas-phase acidity and aromaticity of 1,2-diseleno-3,4-dithiosquaric acid. Theor. Chem. Acc. , 2000, 105,86~92. (IF=2.827)
9. Lixin Zhou, Yongfan Zhang, Liming Wu, Junqian Li. The gas-phase acidity and aromaticity of squaric acid:An ab initio and density functional study. J. Mol. Struct.(Theochem),2000,497,137~144. (IF=1.14)
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