基本情况：
胡琼，博士，副教授。
广州大学，化学化工学院，分析科学技术研究中心
广东省广州市番禺区大学城外环西路230号
邮 编：510006
联系方式：**
E-mail：q.hu@gzhu.edu.cn, q.hu@njust.edu.cn
https://www.researchgate.net/profile/Qiong_Hu13


教育及工作经历
2020/11-至今，广州大学化学化工学院，副教授（广州大学“****”青年杰出人才（B类））
2018/07-2020/10，广州大学化学化工学院，博士后研究员（合作导师：牛利教授）
2013/09-2018/06，南京理工大学环境与生物工程学院，生物化工，工学博士（导师：张学记教授、孔金明教授）
2009/09-2013/07，南京理工大学环境与生物工程学院，生物工程，工学学士


研究兴趣
(1) 生物传感、生物分析与仿生催化
(2) 肿瘤标志物早期诊断
(3) 表界面生物功能化
(4) 新型信号放大策略
(5) 可控/“活性”自由基聚合


科研项目
(1) 国家自然科学基金青年科学基金项目，**，基于eRAFT聚合的信号放大策略及蛋白酶活性高灵敏电化学生物传感研究，2020.01-2022.12，25万元，在研，主持
(2) 广州市博士后科研项目资助经费，gdbsh，基于电化学调控RAFT聚合的高灵敏电化学生物传感研究，2018.08-2020.07，20万元，已结题，主持
(3) 中国博士后科学基金第64批面上资助，2018M643040，基于电化学调控RAFT聚合的高灵敏电化学生物传感研究，2018.08-2020.07，5.0万元，已结题，主持
(4) 国家自然科学基金面上项目，**，基于双极化液/液界面拓宽电位窗应用于电荷存储研究，2020.01-2023.12，64万，在研，主要参与人
(5) 国家自然科学基金面上项目，**，基于肽核酸入侵的微电极阵列高灵敏双链DNA直接测定研究，2016.01-2019.12，65万元，已结题，主要参与人
(6)国家自然科学基金青年科学基金项目，**，基于卟啉仿生纳米探针的电致化学发光核酸传感器的研究，2014.01-2016.12，25万元，已结题，主要参与人
(7)国家自然科学基金委员会科学部主任基金，**，叉指微电极器件上的核酸分子超灵敏电检测研究，2014.01-2014.12，10万元，已结题，主要参与人
(8) 广东省重点领域研发计划项目，2019B，石墨烯/碳纳米管高性能复合导热膜的产业化技术攻关，2019.04-2022.03，1000万，在研，参与(10/19)


文章与专利
(1)Hu Q, Wang Q, Sun G, Kong J*, Zhang X*. Electrochemically mediated surface-initiated de novo growth of polymers for amplified electrochemical detection of DNA. Anal. Chem., 2017, 89, 9253-9259.
(2) Hu Q, Han D, Gan S*, Bao Y, Niu L*. Surface-initiated-reversible-addition–fragmentation-chain-transfer polymerization for electrochemical DNA biosensing. Anal. Chem., 2018, 90, 12207-12213.
(3) Hu Q, Kong J*, Han D, Zhang Y*, Bao Y, Zhang X, Niu L*. Electrochemically controlled RAFT polymerization for highly sensitive electrochemical biosensing of protein kinase activity. Anal. Chem., 2019, 91, 1936-1943.
(4) Hu Q, Bao Y, Gan S, Zhang Y*, Han D, Niu L. Amplified electrochemical biosensing of thrombin activity by RAFT polymerization. Anal. Chem., 2020, 92, 3470-3476.
(5) Hu, Q., Gan, S., Bao, Y., Zhang, Y*., Han, D., Niu, L. Electrochemically controlled ATRP for cleavage-based electrochemical detection of the prostate-specific antigen at femtomolar level concentrations. Anal. Chem., 2020, DOI:10.1021/acs.analchem.0c03467.
(6) Hu Q, Hu W, Kong J*, Zhang X*. Ultrasensitive electrochemical DNA biosensor by exploiting hematin as efficient biomimetic catalyst toward in situ metallization. Biosens. Bioelectron., 2015, 63, 269-275.
(7) Hu Q, Deng X, Yu X, Kong J*, Zhang X*. One-step conjugation of aminoferrocene to phosphate groups as electroactive probes for electrochemical detection of sequence-specific DNA. Biosens. Bioelectron., 2015, 65, 71-77.
(8) Hu Q, Wang Q, Kong J*, Li L, Zhang X*.Electrochemically mediated in situ growth of electroactive polymers for highly sensitive detection of double-stranded DNA without sequence-preference. Biosens. Bioelectron., 2018, 101, 1-6.
(9) Hu Q, Wang Q, Jiang C, Zhang J, Kong J*, Zhang X*. Electrochemically mediated polymerization for highly sensitive detection of protein kinase activity. Biosens. Bioelectron., 2018, 110, 52-57.
(10) Hu Q, Bao Y, Gan S, Zhang Y*, Han D, Niu L*. Electrochemically controlled grafting of polymers for ultrasensitive electrochemical assay of trypsin activity. Biosens. Bioelectron., 2020, 165, 112358.
(11) Hu Q, Kong J*, Han D, Niu L*, Zhang X*. Electrochemical DNA biosensing via electrochemically controlled reversible addition–fragmentation chain transfer polymerization. ACS Sens., 2019, 4, 235-241.
(12) Hu Q, Kong J*, Li Y, Zhang X*. A signal-on electrochemical DNA biosensor based on potential-assisted Cu(I)-catalyzed azide-alkyne cycloaddition mediated labeling of hairpin-like oligonucleotide with electroactive probe. Talanta, 2016, 147, 516-522.
(13) Hu Q, He M, Mei Y, Feng W, Jing S, Kong J*, Zhang X*. Sensitive and selective colorimetric assay of alkaline phosphatase activity with Cu(II)-phenanthroline complex. Talanta, 2017, 163, 146-152.
(14) Hu Q, Ma K, Mei Y, He M, Kong J*, Zhang X*. Metal-to-ligand charge-transfer: Applications to visual detection of β-galactosidase activity and sandwich immunoassay. Talanta, 2017, 167, 253-259.
(15) Hu Q, Kong J*, Han D, Bao Y, Zhang X*, Zhang Y*, Niu L. Ultrasensitive peptide-based electrochemical detection of protein kinase activity amplified by RAFT polymerization. Talanta, 2020, 206, 120173. (高被引论文)
(16) Hu Q, Li L, Sun G, Li D, Kong J*, Huang W, Zhang X*. 5-Carboxyfluorescein: Intrinsic peroxidase-like catalytic activity and its application in the biomimetic synthesis of polyaniline nanoplatelets. J. Mater. Chem. B, 2017, 5, 5937-5941.
(17) Hu Q, Gan S, Bao Y, Zhang Y, Han D, Niu L*. Controlled/“living” radical polymerization-based signal amplification strategies for biosensing. J. Mater. Chem. B, 2020, 8, 3327-3340. (Invited Review)
(18) Hu Q, Zhou B, Dang P, Li L, Kong J*, Zhang X*. Facile colorimetric assay of alkaline phosphatase activity using Fe(II)-phenanthroline reporter. Anal. Chim. Acta, 2017, 950, 170-177.
(19) Hu Q, Hu W, Kong J*, Zhang X*. PNA-based DNA assay with attomolar detection limit based on polygalacturonic acid mediated in-situ deposition of metallic silver on a gold electrode. Microchim. Acta, 2015, 182, 427-434.
(20) Hu Q, Deng X, Kong J*, Dong Y, Liu Q, Zhang X*. Simple and fast electrochemical detection of sequence-specific DNA via click chemistry-mediated labeling of hairpin DNA probes with ethynylferrocene. Analyst, 2015, 140, 4154-4161.
(21) Hu Q, Zhou B, Li F, Kong J*, Zhang X*. Turn‐on colorimetric platform for dual activity detection of acid and alkaline phosphatase in human whole blood. Chem. Asian J., 2016, 11, 3040-3045.
(22) 胡琼，甘世宇，包宇，韩冬雪，牛利*. 基于可控/“活性”自由基聚合的生物传感分析. 化工进展, 2020, 已接收. (中文核心期刊, EI全文收录)
(23) Qian Q, Hu Q, Li L,Shi P, Zhou J, Kong J*, Zhang X, Sun G*, Huang W*. Sensitive fiber microelectrode made of nickel hydroxide nanosheets embedded in highly-aligned carbon nanotube scaffold for nonenzymatic glucose determination.Sens. Actuators, B,2018, 257, 23-28. (co-first author)
(24) Mei Y, Hu Q, Zhou B, Zhang Y, He M, Xu T, Li F, Kong J*. Fluorescence quenching based alkaline phosphatase activity detection. Talanta, 2018, 176, 52-58. (co-first author)
(25) Liu Q, Hu Q, Li L, Kong J*, Zhang X*. Click chemistry-based aptasensor for highly sensitive electrochemical detection of thrombin. Anal. Methods, 2017, 9, 3825-3830. (co-first author)
(26) He M, Hu Q, Mei Y, Zhou B, Kong J*, Zhang X. Metal-to-ligand charge-transfer-based visual detection of alkaline phosphatase activity. Anal. Sci., 2018, 34, 341-347. (co-first author)
(27) Kong J*, Yu X, Hu W, Hu Q, Shui S, Li L, Han X, Xie H, Zhang X*, Wang T*. A biomimetic enzyme modified electrode for H₂O₂ highly sensitive detection. Analyst, 2015, 140, 7792-7798.
(28) Hu W, Hu Q, Li L, Kong J*, Zhang X*. Detection of sequence-specific DNA with a morpholino-functionalized silicon chip. Anal. Methods, 2015, 7, 2406-2412.
(29) Wang Q, Ma K, Yu Z, Ding J, Hu Q, Liu Q, Sun H, Wen D, Liu Q*, Kong J*. The peroxidase-like catalytic activity of ferrocene and its application in the biomimetic synthesis of microsphere polyaniline. New J. Chem., 2018, 42, 13536-13540.
(30) Hu W, Yu X, Hu Q, Kong J*, Li L, Zhang X*. Methyl orange removal by a novel PEI-AuNPs-hemin nanocomposite. J. Environ. Sci., 2017, 53, 278-283.
(31) Xie H*, Gu S, Zhang J, Hu Q, Yu X, Kong J*. Novel PEI–AuNPs–Mn^IIIPPIX nanocomposite with enhanced peroxidase-like catalytic activity in aqueous media.C. R. Chimie,2018, 21, 104-111.
(32) 孔金明，胡琼，何玟辉，梅亚琦，张学记. 一种碱性磷酸酶活性的测定方法. (发明专利，专利号：ZL 2015 1 **.3.)
(33) 孔金明，胡琼，梅亚琦，何玟辉，张学记. 一种酸性磷酸酶活性的测定方法. (发明专利，专利号：ZL 2016 1 **.X)
(34) 孔金明，胡伟文，顾淑梅，胡琼，张学记. 一种基于吗啉寡核苷酸功能化硅基芯片的高选择性DNA荧光分析方法. (发明专利，专利号：ZL 2014 1 **.7)
(35) 孔金明，胡伟文，顾淑梅，胡琼，张学记. 基于吗啉寡核苷酸功能化磁性微球的高灵敏度DNA荧光分析方法. (发明专利，专利号：ZL 2015 1 **.1)
(36) 孔金明，胡伟文，顾淑梅，胡琼，张学记. 基于聚胸腺嘧啶为模板生成铜纳米粒子的高灵敏度DNA荧光分析方法. (发明专利，专利号：ZL 2015 1 **.7)


其他情况
(1) Anal. Chem., Biosens. Bioelectron., Sens. Actuators, B, Electroanalysis和Microchem. J.等国际SCI期刊的资深评审专家。