个人概况
姓名：张建 性别：男
职称：副教授 导师资格：博士生导师 单位：基础医学院
学历：博士 毕业院校：华南师范大学
电子邮件：jianzhang@gzhmu.edu.cn 通信地址：广州番禺区新造镇广州医科大学基础医学院A2-613
招生专业：生物医学工程


研究方向

1. 基于光声成像、超声成像、光学相干成像，开展心脑血管疾病、脑神经疾病和癌症诊疗相关的研究。
2. 开发增强光声成像和光学相干成像的新材料，基于靶向型造影剂开展分子成像。
3. 面向临床需求，开发新的成像方法和成像装置。

所获荣誉
1. 2014年“王大珩高校学生光学奖”
2. 2016年“中国光学重要成果”
指导学生获得的科研项目和奖项

1. 2018年，第五届全国基础医学创新论坛，三等奖，国家级
2. 2019年，广东省大学生课外学术科技作品竞赛“挑战杯”，一等奖，省级
3. 2020年，广东省大学生课外学术科技作品竞赛“挑战杯”，银奖，省级
4. 2020年，广东省大学生电子设计竞赛，二等奖，省级
社会兼职

1. 中国医学装备协会超声装备技术分会超声换能器及材料专委会常务委员
2. 广东省机械工程学会摩擦学分会理事
3. 中国生物医学工程学会高级会员
4. 广东省生物物理学会理事
5. 广东省科技厅科技特派员
6. 广东省食品药品监督管理局医疗器械评审专家
主持科研项目

国家级
一种基于光吸收散射成像活体表征斑马鱼大脑的新方法及其在阿尔兹海默病应用基础研究，国家自然科学基金，30万，结题
省级
牙硬组织铒激光消融后表面变性层快速定量评估方法的研究，广东省自然科学基金，10万，在研
市级
广州市建设高水平大学人才引进项目，50万，在研
部分代表性第一和通讯作者论文：
1) Zhang J, Yang S^*, Ji X, Zhou Q, Xing D^*. Characterization of lipid-rich aortic plaques by intravascular photoacoustic tomography: ex vivo and in vivo validation in a rabbit atherosclerosis model with histologic correlation. Journal of the American College of Cardiology , 2014, 64, 385-390. (SCI, IF=20.589 )
2) Zhang J, Ge W, Yuan Z^*. In vivo three-dimensional characterization of the adult zebrafish brain using a 1325 nm spectral-domain optical coherence tomography system with the 27 frame/s video rate. Biomedical Optics Express, 2015, 6, 3932-3940. (SCI, IF=3.91)
3) Zhang J, Liu J, Wang LM, Li ZY, Yuan Z^*. Retroreflective-type Janus microspheres as a novel contrast agent for enhanced optical coherence tomography. Journal of Biophotonics, 2017,10(6-7):878-886. (SCI, IF=3.763)
4) Zhang J, Zhang Z.-W, Ge W and Yuan Z^*, Long-term in vivo monitoring of injury induced brain regeneration of the adult zebrafish by using spectral domain optical coherence tomography, Chinese Optics Letters, 2016, 14(8): 081702. (SCI, IF=1.907)
5) Zhang J, Chen H, Zhou T, Wang L, Gao D, Zhang X, Liu Y, Wu C^* and Yuan Z^*, A PIID-DTBT based semi-conducting polymer dots with broad and strong optical absorption in the visible-light region: Highly effective contrast agents for multiscale and multi-spectral photoacoustic imaging. Nano Research. 2017, 10(1): 64-76. (SCI, IF=8.515)
6) Zhang J, Pun SH, Yu Y, Gao D, Wang J, Mak PU, Lei KF, Cheng CH, Yuan Z^*. Development of a multi-band photoacoustic tomography imaging system based on a capacitive micromachined ultrasonic transducer array. Applied Optics, 2017, 56(14): 4012-4018. (SCI, IF=1.973)
7) Lin Y, Xiang X, Chen T, & Zhang, J*. In vivo monitoring and high-resolution characterizing of the prednisolone-induced osteoporotic process on adult zebrafish by optical coherence tomography[J]. Biomedical Optics Express, 2019, 10(3): 1184-1195. (SCI, IF=3.91)
8) Lin, Y., Xiang, X., Chen, T., Mao, G., Deng, L., Zeng, L., & Zhang, J*.In vivo monitoring the dynamic process of acute retinal hemorrhage and repair in zebrafish with spectral‐domain optical coherence tomography. Journal of Biophotonics, 2020, DOI: e. (SCI, IF=3.763)
9) Huang, W., Gao, C., Lan, Y., Zeng, S., Pathak, J. L., Zhou, M., ... & Zhang, J*. Optical coherence tomography characterizes the roughness and thickness of the heterogeneous layer on cortical bone surface induced by Er: YAG laser ablation at different moisture contents. Quantitative Imaging in Medicine and Surgery, 2020, 10(3), 713.(SCI, IF=3.074)
10) Lin, Y., Chen, T., Mao, G., Qiu, T., Lan, Y., Xiang, X., ... & Sun, X. D., Zhang J*. Long‐term and in vivo assessment of Aβ protein induced brain atrophy in a zebrafish model by optical coherence tomography. Journal of Biophotonics, 2020, DOI: 10.1002/jbio.. (SCI, IF=3.763)
11) Fan Z, Liu H, Xue Y, Lin J, Fu Y, Xia Z, Pan D, Zhang J*, Qiao K*, Zhang Z, Liao Y*. Reversing cold tumors to hot: An immunoadjuvant-functionalized metal-organic framework for multimodal imaging-guided synergistic photo-immunotherapy. Bioactive Materials 2020, 28;6(2):312-325. .(SCI, IF=8.724)
12) Ting Qiu, Yintao Lan, Weijian Gao, Mengyu Zhou, Shiqi Liu, Wenyan Huang, Sujuan Zeng, Janak L. Pathak, Bin Yang, Jian Zhang*，Photoacoustic imaging as a highly efficient and precise imaging strategy for the evaluation of brain disease, Quantitative Imaging in Medicine and Surgery, 2020, 10.21037/qims-20-845.(SCI, IF=3.074)