- 姓名：张嘉杰
- 性别：男
- 出生年月：1967.07.01
- 专业技术职务：研究员
- 专业：药物化学
- 导师层次：硕士生导师
- 导师类别：学术型
- 最后学历：博士
- 工作单位：药学院
- 办公室电话：48548
- 电子邮件：jjzhang1998@yahoo.com.cn
2.药物分子设计与合成
2.GenipininhibitsendothelialexocytosisvianitricoxideinculturedhumanumbilicalveinendothelialcellsActaPharmacolSin.ActaPharmacolSin.200930(2):202-8.
3.Methyl-1-hydroxy-2-naphthoate,anovelnaphtholderivative,inhibitslipopolysaccharide-inducedinflammatoryresponseinmacrophagesviasuppressionofNF-jB,JNKandp38MAPKpathways.InflammRes.201160(9):851-9.
4.PyranocoumarinsIsolatedfromPeucedanumpraeruptorumDunnSuppressLipopolysaccharide-InducedInflammatoryResponseinMurineMacrophagesThroughInhibitionofNF-κBandSTAT3Activation.Inflammation.2012,35(3):967-77.
5.Combined3D-QSARandDockingModellingStudyonindolocarbazoleSeriesCompoundsasTie-2Inhibitors.Int.J.Mol.Sci.2011,12,5080-5097
6.DesignandSynthesisofSomeNovel2,3,4,5-Tetrahydro-1H-pyridoΒ,3-b]indolesasPotentialc-MetInhibitors.HelveticaChimicaActa2012,95，320-326
7.Design,synthesisandmoleculardockingstudiesofsomenovelspiro[indoline-3,4’-piperidine]-2-onesaspotentialc-Metinhibitors.EurJMedChem.201250:370-5.
8.PyrroloΑ,2-d]pyrimidineDerivativesasTypeIIKinaseInsertDomainReceptor(KDR)Inhibitors:CoMFAandCoMSIAStudies.IntJMolSci.201213(2):2387-404.
2.基于HIVgp41融合多肽的新型抗艾滋病药物研究省国际合作项目2012-201430万元
3.新型VEGFR酪氨酸激酶抑制剂IPC-032-032对Wnt/β-catenin信号异常活化的结肠癌细胞合成致死效应的分子机理国家自然科学基金2012-201314万元
