- 姓名：廖禹林
- 性别：男
- 出生年月：1965年2月
- 专业技术职务：教授副主任医师
- 专业：心血管内科学
- 导师层次：博士生导师
- 导师类别：学术型
- 最后学历：博士
- 工作单位：南方医科大学南方医院心血管内科
- 办公室电话：020-62786294
- 电子邮件：liao18@msn.com
2.中国休克微循环委员会委员
1.LiaoY,BinJ,AsakuraM,XuanW,ChenB,HuangQ,XuD,LedentC,TakashimaS,KitakazeM.Deficiencyoftype1cannabinoidreceptorsworsensacuteheartfailureinducedbypressureoverloadinmice.EurHeartJ.2011Jul23.[Epubaheadofprint](IF10.478)
2.XuanW,LiaoY*(co-first),ChenB,HuangQ,XuD,LiuY,BinJ,KitakazeM.Detrimentaleffectoffractalkineonmyocardialischemiaandheartfailure.CardiovascRes.2011,92(3):385-93.[Epubaheadofprint](IF6.051)
3.XuanW,WuB,ChenC,ChenB,ZhangW,XuD,BinJ,LiaoY.Resveratrolimprovesmyocardialischemiaandischemicheartfailureinmicebyantagonizingthedetrimentaleffectsoffractalkine.CritCareMed.2012Aug24.[Epubaheadofprint](IF6.33)
4.LiaoY,BinJ,LuoT,ZhaoH,LedentC,Asakura,M,XuD,TakashimaS,KitakazeM.CB1cannabinoidreceptordeficiencypromotescardiacremodelinginducedbypressureoverloadinmice.IntJCardiol.2012May30.[Epubaheadofprint](IF7.08)
5.LiaoY,TakashimaS,MaedaN,OuchiN,KomamuraK,ShimomuraI,HoriM,MatsuzawaY,FunahashiT,KitakazeM.Exacerbationofheartfailureinadiponectin-deficientmiceduetoimpairedregulationofAMPKandglucosemetabolism.CardiovascRes.200567:705-13.(IF6.051)
6.LiaoY,AsakuraM,TakashimaS,OgaiA,AsanoY,ShintaniY,MinaminoT,AsanumaH,SanadaS,KimJ,KitamuraS,TomoikeH,HoriM,KitakazeM.Celiprolol,avasodilatorybeta-blocker,inhibitspressureoverload-inducedcardiachypertrophyandpreventsthetransitiontoheartfailurevianitricoxide-dependentmechanismsinmice.Circulation.2004110:692-9.(IF14.816)
7.LiaoY,TakashimaS,AsanoY,AsakuraM,OgaiA,ShintaniY,MinaminoT,AsanumaH,SanadaS,KimJ,OgitaH,TomoikeH,HoriM,KitakazeM.ActivationofadenosineA1receptorattenuatescardiachypertrophyandpreventsheartfailureinmurineleftventricularpressure-overloadmodel.CircRes.200393:759-66.(IF9.214)
8.LiaoY,AsakuraM,TakashimaS,OgaiA,AsanoY,AsanumaH,MinaminoT,TomoikeH,HoriM,KitakazeM.Benidipine,along-actingcalciumchannelblocker,inhibitscardiacremodelinginpressure-overloadedmice.CardiovascRes.200565:879-88.(IF6.051)
2、第十届在日中国人留学成果论文报告会上获中国驻日本国大使奖2005年11月中国驻日本国大使馆
3、军队科技进步奖1998年5月兰州军区后勤部三等奖
4、北京市科技进步二等奖2006年
2.广东省高等学校人才引进项目结合分子影像技术研究血管内皮功能对慢性心衰的诊治意义课题主持人额度100万时间：2009.9-2012.8
3.南方医科大学优秀人才引进启动基金心脏肥大细胞在慢性心衰中的作用课题主持人额度：30万时间：2009.3-2012.3
4．广东省高等学校高层次人才项目不规则趋化因子在心肌缺血和心力衰竭中的作用与机制课题主持人额度：25万时间：2011.5-2013.4
5.国家自然科学基金面上项目：自噬在心肌缺血再灌注损伤中的不同作用（81170146）课题主持人额度：60万时间：2012.1-2015.12
6.广东省自然科学基金团队项目以新型超声分子探针诊治动脉粥样斑块的基础研究核心成员额度：250万时间：2012.1-2016.12
7.国家重大科学研究计划血管发育和稳态维持的遗传及表观遗传机制（2012CB945100）骨干成员额度：70万
8.国家自然科学基金面上项目：成纤维细胞生长因子23在不规则趋化因子介导的心肌纤维化中的信号转导作用（31271513）课题主持人额度70万时间2013.1-2016.12
9.南方医院对国家自然基金1:1配套，共130万
本人目前可支配总经费约300万
本人的研究水平和业绩，在国内同行中处于领先水平。
SCI论文目录（共51篇，LiaoY为本人）：
1.XuanW,WuB,ChenC,ChenB,ZhangW,XuD,BinJ,LiaoY.Resveratrolimprovesmyocardialischemiaandischemicheartfailureinmicebyantagonizingthedetrimentaleffectsoffractalkine.CritCareMed.2012.
2.ShiM,HuangW,LinL,ZhengD,ZuoQ,WangL,WangN,WuY,LiaoY,LiaoW.SilencingofXB130IsAssociatedwithBoththePrognosisandChemosensitivityofGastricCancer.PLoSOne.20127(8):e41660.
3.LiaoY,BinJ,LuoT,ZhaoH,LedentC,AsakuraM,XuD,TakashimaS,KitakazeM.CB1cannabinoidreceptordeficiencypromotescardiacremodelinginducedbypressureoverloadinmice.IntJCardiol.2012.
4.ChenD,LiaoY,XuQ,LiY,WuW,WuJ,LiaoW,XuD,LiuY,WuP,BinJ.Persistenceofsystolicanddiastolicregionaldysfunctionafterbriefepisodesofmyocardialischemiaevaluatedwithvelocityvectorimaging.IntJCardiol.2012.
5.ZuoQ,HuangH,ShiM,ZhangF,SunJ,BinJ,LiaoY,LiaoW.Multivariateanalysisofseveralmolecularmarkersandclinicopathologicalfeaturesinpostoperativeprognosisofhepatocellularcarcinoma.AnatRec(Hoboken).2012295(3):423-431.
6.XuanW,LiaoY,ChenB,HuangQ,XuD,LiuY,BinJ,KitakazeM.Detrimentaleffectoffractalkineonmyocardialischaemiaandheartfailure.CardiovascRes.201192(3):385-393.
7.HuG,LiuC,LiaoY,YangL,HuangR,WuJ,XieJ,BundhooK,LiuY,BinJ.UltrasoundmolecularimagingofarterialthrombiwithnovelmicrobubblesmodifiedbycyclicRGDinvitroandinvivo.ThrombHaemost.2011107(1):172-183.
8.LiaoY,LinL,LuD,FuY,BinJ,XuD,KitakazeM.ActivationofadenosineA1receptorattenuatestumornecrosisfactor-alphainducedhypertrophyofcardiomyocytes.BiomedPharmacother.201165(7):491-495.
9.XieJ,LiaoY,YangL,WuJ,LiuC,XuanW,LiM,ZhangL,LiuY,WuP,BinJ.Ultrasoundmolecularimagingofangiogenesisinducedbymutantformsofhypoxia-induciblefactor-1alpha.CardiovascRes.201192(2):256-266.
10.LiaoY,BinJ,AsakuraM,XuanW,ChenB,HuangQ,XuD,LedentC,TakashimaS,KitakazeM.Deficiencyoftype1cannabinoidreceptorsworsensacuteheartfailureinducedbypressureoverloadinmice.EurHeartJ.2011.
11.WuJ,Leong-PoiH,BinJ,YangL,LiaoY,LiuY,CaiJ,XieJ.Efficacyofcontrast-enhancedUSandmagneticmicrobubblestargetedtovascularcelladhesionmolecule-1formolecularimagingofatherosclerosis.Radiology.2011260(2):463-471.
12.ZhaoJ,ZengZ,YanL,JiLJ,LuoT,BinJP,LiaoYL.[Echocardiographicevaluationofpressureoverload-inducedcardiacremodelinginmiceusingdifferentultrasoundmachines].NanFangYiKeDaXueXueBao.201131(3):443-447.
13.ChenX,ZhaD,XiuJ,LiaoY,CuiK,LinH,JianZ,HuF,HuangX,ZhouB,HuangQ,BinJ,LiuY.Anewhydrodynamicapproachbyinfusionofdrag-reducingpolymerstoimproveleftventricularfunctioninratswithmyocardialinfarction.IntJCardiol.2011147(1):112-117.
14.YanY,LiaoY,YangL,WuJ,DuJ,XuanW,JiL,HuangQ,LiuY,BinJ.Late-phasedetectionofrecentmyocardialischaemiausingultrasoundmolecularimagingtargetedtointercellularadhesionmolecule-1.CardiovascRes.201189(1):175-183.
15.FuHY,OkadaK,LiaoY,TsukamotoO,IsomuraT,AsaiM,SawadaT,OkudaK,AsanoY,SanadaS,AsanumaH,AsakuraM,TakashimaS,KomuroI,KitakazeM,MinaminoT.AblationofC/EBPhomologousproteinattenuatesendoplasmicreticulum-mediatedapoptosisandcardiacdysfunctioninducedbypressureoverload.Circulation.2010122(4):361-369.
16.LuoQ,XuanWL,XiF,LiaoYL,KitakazeM.[AntihypertrophiceffectofdihyyridinescalciumchannelblockersisdependentontheirpotentialofblockingN-typecalciumchannel].NanFangYiKeDaXueXueBao.201030(4):755-759.
17.MinKD,AsakuraM,LiaoY,NakamaruK,OkazakiH,TakahashiT,FujimotoK,ItoS,TakahashiA,AsanumaH,YamazakiS,MinaminoT,SanadaS,SeguchiO,NakanoA,AndoY,OtsukaT,FurukawaH,IsomuraT,TakashimaS,MochizukiN,KitakazeM.Identificationofgenesrelatedtoheartfailureusingglobalgeneexpressionprofilingofhumanfailingmyocardium.BiochemBiophysResCommun.2010393(1):55-60.
18.LiaoY,XuanW,ZhaoJ,BinJ,ZhaoH,AsakuraM,FunahashiT,TakashimaS,KitakazeM.Antihypertrophiceffectsofadiponectinoncardiomyocytesareassociatedwiththeinhibitionofheparin-bindingepidermalgrowthfactorsignaling.BiochemBiophysResCommun.2010393(3):519-525.
19.XuRF,SunJP,ZhangSR,ZhuGS,LiLB,LiaoYL,XieJM,LiaoWJ.KRASandPIK3CAbutnotBRAFgenesarefrequentlymutatedinChinesecholangiocarcinomapatients.BiomedPharmacother.201065(1):22-26.
20.LiaoW,LiaoY,ZhouJX,XieJ,ChenJ,HuangW,LuoR.GenemutationsinepidermalgrowthfactorreceptorsignalingnetworkandtheirassociationwithsurvivalinChinesepatientswithmetastaticcolorectalcancers.AnatRec(Hoboken).2010293(9):1506-1511.
21.ZhaoH,LiaoY,MinaminoT,AsanoY,AsakuraM,KimJ,AsanumaH,TakashimaS,HoriM,KitakazeM.Inhibitionofcardiacremodelingbypravastatinisassociatedwithameliorationofendoplasmicreticulumstress.HypertensRes.200831(10):1977-1987.
22.LiF,ZhaoH,LiaoY,TakashimaS,AsanoY,ShintaniY,HoriM,KitakazeM.Highermortalityinheterozygousneuropilin-1miceaftercardiacpressureoverload.BiochemBiophysResCommun.2008370(2):317-321.
23.LiaoY,ZhaoH,OgaiA,KatoH,AsakuraM,KimJ,AsanumaH,MinaminoT,TakashimaS,KitakazeM.Atorvastatinslowstheprogressionofcardiacremodelinginmicewithpressureoverloadandinhibitsepidermalgrowthfactorreceptoractivation.HypertensRes.200831(2):335-344.
24.YamamotoH,TakashimaS,ShintaniY,YamazakiS,SeguchiO,NakanoA,HigoS,KatoH,LiaoY,AsanoY,MinaminoT,MatsumuraY,TakedaH,KitakazeM.IdentificationofanovelsubstrateforTNFalpha-inducedkinaseNUAK2.BiochemBiophysResCommun.2008365(3):541-547.
25.AsakuraM,AsanumaH,KimJ,LiaoY,NakamaruK,FujitaM,KomamuraK,IsomuraT,FurukawaH,TomoikeH,KitakazeM.Impactofadenosinereceptorsignalingandmetabolismonpathophysiologyinpatientswithchronicheartfailure.HypertensRes.200730(9):781-787.
26.FujitaM,AsanumaH,KimJ,LiaoY,HirataA,TsukamotoO,MinaminoT,HoriM,GotoM,NodeK,KitakazeM.Impairedglucosetolerance:apossiblecontributortoleftventricularhypertrophyanddiastolicdysfunction.IntJCardiol.2007118(1):76-80.
27.ShintaniY,TakashimaS,AsanoY,KatoH,LiaoY,YamazakiS,TsukamotoO,SeguchiO,YamamotoH,FukushimaT,SugaharaK,KitakazeM,HoriM.Glycosaminoglycanmodificationofneuropilin-1modulatesVEGFR2signaling.EMBOJ.200625(13):3045-3055.
28.LiaoY,TakashimaS,ZhaoH,AsanoY,ShintaniY,MinaminoT,KimJ,FujitaM,HoriM,KitakazeM.Controlofplasmaglucosewithalpha-glucosidaseinhibitorattenuatesoxidativestressandslowstheprogressionofheartfailureinmice.CardiovascRes.200670(1):107-116.
29.TsukamotoO,MinaminoT,OkadaK,ShintaniY,TakashimaS,KatoH,LiaoY,OkazakiH,AsaiM,HirataA,FujitaM,AsanoY,YamazakiS,AsanumaH,HoriM,KitakazeM.Depressionofproteasomeactivitiesduringtheprogressionofcardiacdysfunctioninpressure-overloadedheartofmice.BiochemBiophysResCommun.2006340(4):1125-1133.
30.TsukamotoO,MinaminoT,SanadaS,OkadaK,HirataA,FujitaM,ShintaniY,YulinL,AsanoY,TakashimaS,YamasakiS,TomoikeH,HoriM,KitakazeM.Theantagonismofaldosteronereceptorpreventsthedevelopmentofhypertensiveheartfailureinducedbychronicinhibitionofnitricoxidesynthesisinrats.CardiovascDrugsTher.200620(2):93-102.
31.FujitaM,OkudaH,TsukamotoO,AsanoY,HirataYL,KimJ,MiyatsukaT,TakashimaS,MinaminoT,TomoikeH,KitakazeM.BlockadeofangiotensinIIreceptorsreducestheexpressionofreceptorsforadvancedglycationendproductsinhumanendothelialcells.ArteriosclerThrombVascBiol.200626(10):e138-142.
32.LiaoY,TakashimaS,MaedaN,OuchiN,KomamuraK,ShimomuraI,HoriM,MatsuzawaY,FunahashiT,KitakazeM.Exacerbationofheartfailureinadiponectin-deficientmiceduetoimpairedregulationofAMPKandglucosemetabolism.CardiovascRes.200567(4):705-713.
33.LiaoY,AsakuraM,TakashimaS,OgaiA,AsanoY,AsanumaH,MinaminoT,TomoikeH,HoriM,KitakazeM.Benidipine,along-actingcalciumchannelblocker,inhibitscardiacremodelinginpressure-overloadedmice.CardiovascRes.200565(4):879-888.
34.LiaoY,AsakuraM,TakashimaS,KatoH,AsanoY,ShintaniY,MinaminoT,TomoikeH,HoriM,KitakazeM.AmlodipineamelioratesmyocardialhypertrophybyinhibitingEGFRphosphorylation.BiochemBiophysResCommun.2005327(4):1083-1087.
35.ShintaniY,NodeK,AsanumaH,SanadaS,TakashimaS,AsanoY,LiaoY,FujitaM,HirataA,ShinozakiY,FukushimaT,NagamachiY,OkudaH,KimJ,TomoikeH,HoriM,KitakazeM.OpeningofCa2+-activatedK+channelsisinvolvedinischemicpreconditioningincaninehearts.JMolCellCardiol.200437(6):1213-1218.
36.OkadaK,MinaminoT,TsukamotoY,LiaoY,TsukamotoO,TakashimaS,HirataA,FujitaM,NagamachiY,NakataniT,YutaniC,OzawaK,OgawaS,TomoikeH,HoriM,KitakazeM.Prolongedendoplasmicreticulumstressinhypertrophicandfailingheartafteraorticconstriction:possiblecontributionofendoplasmicreticulumstresstocardiacmyocyteapoptosis.Circulation.2004110(6):705-712.
37.LiaoY,AsakuraM,TakashimaS,OgaiA,AsanoY,ShintaniY,MinaminoT,AsanumaH,SanadaS,KimJ,KitamuraS,TomoikeH,HoriM,KitakazeM.Celiprolol,avasodilatorybeta-blocker,inhibitspressureoverload-inducedcardiachypertrophyandpreventsthetransitiontoheartfailurevianitricoxide-dependentmechanismsinmice.Circulation.2004110(6):692-699.
38.AsanumaH,MinaminoT,SanadaS,TakashimaS,OgitaH,OgaiA,AsakuraM,LiaoY,AsanoY,ShintaniY,KimJ,ShinozakiY,MoriH,NodeK,KitamuraS,TomoikeH,HoriM,KitakazeM.Beta-adrenoceptorblockercarvedilolprovidescardioprotectionviaanadenosine-dependentmechanisminischemiccaninehearts.Circulation.2004109(22):2773-2779.
39.AsanoY,TakashimaS,AsakuraM,ShintaniY,LiaoY,MinaminoT,AsanumaH,SanadaS,KimJ,OgaiA,FukushimaT,OikawaY,OkazakiY,KanedaY,SatoM,MiyazakiJ,KitamuraS,TomoikeH,KitakazeM,HoriM.Lamr1functionalretroposoncausesrightventriculardysplasiainmice.NatGenet.200436(2):123-130.
40.OgitaH,NodeK,LiaoY,IshikuraF,BeppuS,AsanumaH,SanadaS,TakashimaS,MinaminoT,HoriM,KitakazeM.Raloxifenepreventscardiachypertrophyanddysfunctioninpressure-overloadedmice.Hypertension.200443(2):237-242.
41.LiaoY,TakashimaS,AsanoY,AsakuraM,OgaiA,ShintaniY,MinaminoT,AsanumaH,SanadaS,KimJ,OgitaH,TomoikeH,HoriM,KitakazeM.ActivationofadenosineA1receptorattenuatescardiachypertrophyandpreventsheartfailureinmurineleftventricularpressure-overloadmodel.CircRes.200393(8):759-766.
42.AsakuraM,TakashimaS,AsanoY,HonmaT,AsanumaH,SanadaS,ShintaniY,LiaoY,KimJ,OgitaH,NodeK,MinaminoT,YorikaneR,AgaiA,KitamuraS,TomoikeH,HoriM,KitakazeM.CanineDNAarrayasapotentialtoolforcombiningphysiologyandmolecularbiology.CircJ.200367(9):788-792.
43.SanadaS,NodeK,MinaminoT,TakashimaS,OgaiA,AsanumaH,OgitaH,LiaoY,AsakuraM,KimJ,HoriM,KitakazeM.Long-actingCa2+blockerspreventmyocardialremodelinginducedbychronicNOinhibitioninrats.Hypertension.200341(4):963-967.
44.OgitaH,NodeK,AsanumaH,SanadaS,LiaoY,TakashimaS,AsakuraM,MoriH,ShinozakiY,HoriM,KitakazeM.Ameliorationofischemia-andreperfusion-inducedmyocardialinjurybytheselectiveestrogenreceptormodulator,raloxifene,inthecanineheart.JAmCollCardiol.200240(5):998-1005.
45.SanadaS,NodeK,AsanumaH,OgitaH,TakashimaS,MinaminoT,AsakuraM,LiaoY,OgaiA,KimJ,HoriM,KitakazeM.Openingoftheadenosinetriphosphate-sensitivepotassiumchannelattenuatescardiacremodelinginducedbylong-terminhibitionofnitricoxidesynthesis:roleof70-kDaS6kinaseandextracellularsignal-regulatedkinase.JAmCollCardiol.200240(5):991-997.
46.AsakuraM,KitakazeM,SakataY,AsanumaH,SanadaS,KimJ,OgidaH,LiaoY,NodeK,TakashimaS,TadaM,HoriM.Adenosine-inducedcardiacgeneexpressionofischemicmurineheartsrevealedbycDNAarrayhybridization.CircJ.200266(1):93-96.
47.LiaoY,IshikuraF,BeppuS,AsakuraM,TakashimaS,AsanumaH,SanadaS,KimJ,OgitaH,KuzuyaT,NodeK,KitakazeM,HoriM.EchocardiographicassessmentofLVhypertrophyandfunctioninaortic-bandedmice:necropsyvalidation.AmJPhysiolHeartCircPhysiol.2002282(5):H1703-1708.
48.AsakuraM,KitakazeM,TakashimaS,LiaoY,IshikuraF,YoshinakaT,OhmotoH,NodeK,YoshinoK,IshiguroH,AsanumaH,SanadaS,MatsumuraY,TakedaH,BeppuS,TadaM,HoriM,HigashiyamaS.CardiachypertrophyisinhibitedbyantagonismofADAM12processingofHB-EGF:metalloproteinaseinhibitorsasanewtherapy.NatMed.20028(1):35-40.
49.TakemotoM,NodeK,NakagamiH,LiaoY,GrimmM,TakemotoY,KitakazeM,LiaoJK.Statinsasantioxidanttherapyforpreventingcardiacmyocytehypertrophy.JClinInvest.2001108(10):1429-1437.
50.SanadaS,KitakazeM,NodeK,TakashimaS,OgaiA,AsanumaH,SakataY,AsakuraM,OgitaH,LiaoY,FukushimaT,YamadaJ,MinaminoT,KuzuyaT,HoriM.DifferentialsubcellularactionsofACEinhibitorsandAT(1)receptorantagonistsoncardiacremodelinginducedbychronicinhibitionofNOsynthesisinrats.Hypertension.200138(3):404-411.
51.SanadaS,KitakazeM,PapstPJ,AsanumaH,NodeK,TakashimaS,AsakuraM,OgitaH,LiaoY,SakataY,OgaiA,FukushimaT,YamadaJ,ShinozakiY,KuzuyaT,MoriH,TeradaN,HoriM.CardioprotectiveeffectaffordedbytransientexposuretophosphodiesteraseIIIinhibitors:theroleofproteinkinaseAandp38mitogen-activatedproteinkinase.Circulation.2001104(6):705-710.
