佟超
浙江大学生命科学研究院教授，博士生导师
1977年9月出生于内蒙古包头市


教育经历：
1995-1999：南开大学生命科学院学士
1999-2002：中国科学院动物研究所硕士
2002-2006：美国德克萨斯大学西南医学中心（UTSW）博士
工作经历:
2006-2010：美国贝勒医学院（Baylor College of Medicine）人类分子遗传学系博士后
2011-至今：浙江大学生命科学研究院教授，博士生导师
代表性论文：
1.Tian, X.J., Gala, U., Zhang, Y.P., Shang, W.N., Jaiswal, S., Ronza, A., Jaiswal, M., Yamamoto, S., Sandoval, H., Duraine, L., Sardiello, M., Sillitoe, R., Venkatachalam, K ., Fan, H.Y., Bellen, H.J. *, Tong, C*(2015). A Voltage gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasis. PLOS Bio. In press (* co-correspondence author)
2.Yu, J., Wu, H., Wen, Y., Liu, Y. J., Zhou, T., Ni, B., Lin, Y., Dong, J., Zhou, Z., Hu, Z. B.*, Guo, X. J.*, Sha, J. H.*, Tong, C*. (2015). Identification of seven genes essential for male fertility through a genome-wide association study of non-obstructive azoospermia and RNA interference-mediated large-scale functional screening in Drosophila. Hum Mol Genet. in press (* co-correspondence author)
3．Hu, Z. B.*, Li, Z.*, Yu, J.*, Tong, C.*, Lin, Y.*, Guo, X.*, Lu, F. , Dong, J., Xia, Y., Wen, Y., Wu, H., Li, H., Zhu, Y., Ping, Y., Chen, X., Dai, J., Jiang, Y., Pan, S., Xu, P., Luo, K., Du, Q., Yao, B., Liang, M., Gui, Y., Weng, Y., Lu,H., Wang, Z., Zhang, F., Zhu, X., Yang, X., Zhang, Z., Zhao, H., Xiong, C., Ma, H., Jin, G., Chen, F., Xu, J., Wang, X., Zhou, Z., Chen, Z., Liu, J., Shen, H., Sha, J. H. (2014). Association analysis identifies new risk loci for non-obstructive azoospermia in Chinese men. Nat Commun, 23;5:3857 (* co-first author)
4.Yu, C., Zhang, Y.L., Pan, W.W., Li, X.M., Wang, Z.W., Ge, Z.J., Zhou, J.J., Cang, Y., Tong, C., Sun, Q.Y., et al. (2013). CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science 342:1518-1521.
5.Tong, C., Ohyama, T., Tien, A.C., Rajan, A., Haueter, C.M., and Bellen, H.J. (2011). Rich regulates target specificity of photoreceptor cells and N-cadherin trafficking in the Drosophila visual system via Rab6. Neuron 71:447-459.
6.Jia, H., Liu, Y., Xia, R., Tong, C., Yue, T., Jiang, J., and Jia, J. (2010). Casein kinase 2 promotes Hedgehog signaling by regulating both smoothened and Cubitus interruptus. J Biol Chem 285:37218-37226.
7.Chen, Y., Li, S., Tong, C., Zhao, Y., Wang, B., Liu, Y., Jia, J., and Jiang, J. (2010). G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila. Genes Dev 24:2054-2067.
8.Bellen, H.J., Tong, C., and Tsuda, H. (2010). 100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future. Nat Rev Neurosci 11:514-522.
9.Tsuda, H., Han, S.M., Yang, Y., Tong, C., Lin, Y.Q., Mohan, K., Haueter, C., Zoghbi, A., Harati, Y., Kwan, J., et al. (2008). The amyotrophic lateral sclerosis 8 protein VAPB is cleaved, secreted, and acts as a ligand for Eph receptors. Cell 133:963-977.
10.Zhao, Y.*, Tong, C.*, and Jiang, J. (2007). Hedgehog regulates smoothened activity by inducing a conformational switch. Nature 450:252-258. (* co-first author)
11.Zhao, Y., Tong, C., and Jiang, J. (2007). Transducing the Hedgehog signal across the plasma membrane. Fly (Austin) 1:333-336.
12.Tong, C., and Jiang, J. (2007). Using immunoprecipitation to study protein-protein interactions in the Hedgehog-signaling pathway. Methods Mol Biol 397:215-229.
13.Zhang, W., Zhao, Y., Tong, C., Wang, G., Wang, B., Jia, J., and Jiang, J. (2005). Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus. Dev Cell 8:267-278.
14.Jia, J., Zhang, L., Zhang, Q., Tong, C., Wang, B., Hou, F., Amanai, K., and Jiang, J. (2005). Phosphorylation by double-time/CKIepsilon and CKIalpha targets cubitus interruptus for Slimb/beta-TRCP-mediated proteolytic processing. Dev Cell 9:819-830.
15.Jia, J.*, Tong, C.*, Wang, B., Luo, L., and Jiang, J. (2004). Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I. Nature 432:1045-1050. (* co-first author)
16.Yao, L.J., Fan, H.Y., Tong, C., Chen, D.Y., Schatten, H., and Sun, Q.Y. (2003). Polo-like kinase-1 in porcine oocyte meiotic maturation, fertilization and early embryonic mitosis. Cell Mol Biol (Noisy-le-grand) 49:399-405.
17.Tong, C., Fan, H.Y., Chen, D.Y., Song, X.F., Schatten, H., and Sun, Q.Y. (2003). Effects of MEK inhibitor U0126 on meiotic progression in mouse oocytes: microtuble organization, asymmetric division and metaphase II arrest. Cell Res 13:375-383.
18.Moskalenko, S., Tong, C., Rosse, C., Mirey, G., Formstecher, E., Daviet, L., Camonis, J., and White, M.A. (2003). Ral GTPases regulate exocyst assembly through dual subunit interactions. J Biol Chem 278:51743-51748.
19.Jia, J., Tong, C., and Jiang, J. (2003). Smoothened transduces Hedgehog signal by physically interacting with Costal2/Fused complex through its C-terminal tail. Genes Dev 17:2709-2720.
20.Fan, H.Y., Tong, C., Teng, C.B., Lian, L., Li, S.W., Yang, Z.M., Chen, D.Y., Schatten, H., and Sun, Q.Y. (2003). Characterization of Polo-like kinase-1 in rat oocytes and early embryos implies its functional roles in the regulation of meiotic maturation, fertilization, and cleavage. Mol Reprod Dev 65:318-329.
21.Fan, H.Y., Tong, C., Lian, L., Li, S.W., Gao, W.X., Cheng, Y., Chen, D.Y., Schatten, H., and Sun, Q.Y. (2003). Characterization of ribosomal S6 protein kinase p90rsk during meiotic maturation and fertilization in pig oocytes: mitogen-activated protein kinase-associated activation and localization. Biol Reprod 68:968-977.
22.Cheng, Y., Fan, H.Y., Wen, D.C., Tong, C., Zhu, Z.Y., Lei, L., Sun, Q.Y., and Chen, D.Y. (2003). Asynchronous cytoplast and karyoplast transplantation reveals that the cytoplasm determines the developmental fate of the nucleus in mouse oocytes. Mol Reprod Dev 65:278-282.
23.Tong, C., Fan, H.Y., Lian, L., Li, S.W., Chen, D.Y., Schatten, H., and Sun, Q.Y. (2002). Polo-like kinase-1 is a pivotal regulator of microtubule assembly during mouse oocyte meiotic maturation, fertilization, and early embryonic mitosis. Biol Reprod 67:546-554.
24.Fan, H.Y., Tong, C., Li, M.Y., Lian, L., Chen, D.Y., Schatten, H., and Sun, Q.Y. (2002). Translocation of the classic protein kinase C isoforms in porcine oocytes: implications of protein kinase C involvement in the regulation of nuclear activity and cortical granule exocytosis. Exp Cell Res 277:183-191.
25.Fan, H.Y., Li, M.Y., Tong, C., Chen, D.Y., Xia, G.L., Song, X.F., Schatten, H., and Sun, Q.Y. (2002). Inhibitory effects of cAMP and protein kinase C on meiotic maturation and MAP kinase phosphorylation in porcine oocytes. Mol Reprod Dev 63:480-487.