张改云 副研究员
招生资格：

邮 箱 ：

招生专业：

研究方向：



个人简介：

基本信息
张改云，女，1980年10月生，副研究员。
研究领域
深海放线菌资源研究与开发，主要研究方向包括：
1.海洋放线菌的多样性研究，包括大洋不同生境放线菌菌株资源获取、分类及其潜力评估；
2.基于基因组信息的新颖天然产物的挖掘；
3.微生物次级代谢产物关键合成途径的基因功能研究。




发表文章：


近期部分发表的文章：
1)WuQ,DeeringRW,ZhangG,WangB,LiX,SunJ,ChenJ,ZhangH,RowleyDC,WangH. 2018.Albisporachelin, a New Hydroxamate Type Siderophore from the Deep Ocean Sediment-Derived Actinomycete WP1. Mar Drugs.16(6)
2)Wu Q, Zhang G, Wang B, Li X, Yue S, Chen J, Zhang H, Wang H. 2018. Production and Identification of Inthomycin B Produced by a Deep-Sea Sediment-Derived Streptomyces sp. YB104 Based on Cultivation-Dependent Approach. Curr Microbiol. 75(7).https://doi.org/10.1007/s00284-018-1469-1.
3)Gaiyun Zhang, Lina Wang, Jinglong Li, Yuan Zhou. 2017. Pseudonocardia profundimarissp. nov., isolated from marine sediment. Int J Syst Evol Microbiol 67: 1693-1697.
4)S Niu, TT Zhou, CL Xie, GY Zhang, XW Yang. 2017. Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207. Mar Drugs 15(7).
5)Wang S,Zhou Y,Zhang G. 2016. Nocardioides flavussp. nov., isolated from marine sediment. Int J Syst Evol Microbiol.66: 5275-5280.
6)CL Xie, SW Niu, TT Zhou, GY Zhang, Q Yang, XW Yang. 2016. Chemical constituents and chemotaxonomic study on themarine actinomycete Williamsiasp. MCCC 1A11233. Biochemical Systematics and Ecology.67:129-133.
7)Zhang G, Yang Y, Wang L.2016.Altererythrobacter aurantiacussp. nov., isolated from deep-sea sediment.Antonie Van Leeuwenhoek. 109(9):1245-1251.
8)Zhang G, Wang L, Li J, Zhou Y.2016. Amycolatopsis albispora sp. nov., isolated from deep-sea sediment.Int J Syst Evol Microbiol.66: 3860-3864.
9)Wang L, LiJ, Zhang G. 2016. Nocardioides rotundus sp. nov., isolated from deep seawater. Int J Syst Evol Microbiol. 66(5):1932-1936.
10)Zhang G,Wang S, Wang L.2016. Sediminivirga luteolagen. nov., sp. nov., a member of the family Brevibacteriaceae, isolated from marine sediment. Int J Syst Evol Microbiol. 66: 1494-1498.
11)Wang S, Xu X, Wang L, Jiao K, Zhang G.2015. Georgenia subflavasp. nov., isolated from a deep-sea sediment. Int J Syst Evol Microbiol. 65:4146-4150.
12)Zhang G,Yang Y, Wang S, Sun Z, Jiao K. 2015.Alkalimicrobium pacificumgen. nov., sp. nov., a marine bacterium in the family Rhodobacteraceae. Int J Syst Evol Microbiol.65: 2453-2458
13)Zhang G, Zhang Y, Yin X,Wang S. 2015. Nesterenkonia alkaliphilasp. nov., a novel alkaliphilic, halotolerant actinobacteria isolated from the western Pacific Ocean. Int J Syst Evol Microbiol.65(2):516-521.
14)Yin X, Yang Y, Wang S,Zhang G. 2015. Virgibacillus oceanisp. nov. isolated from oceansediment. Int J Syst Evol Microbiol.65:159–164.
15)XW Yang,Z Miao, XN Ma, GY Zhang, A Steinmetz. B Yang,JF Wang, JLiu, YHLiu, N Wang. 2015. Asterolloside, a novel enolic saccharide from the sea star Asteriasrollestoni Bell. Tetrahedron Letters. 56:6174–6176.
16)Zhang G, Yang Y, Yin X, Wang S. 2014.Paracoccus pacificussp. nov., isolated from the Western Pacific Ocean. Antonie Van Leeuwenhoek. 106(4):725-731.
17)Yang Y, Zhang G, Sun Z, Cheung MK, Huang C. 2014.Altererythrobacter oceanensis sp. nov., isolated from the Western Pacific.Antonie Van Leeuwenhoek. 106(6):1191-1198.
18)Zhang Y,Ren H,Zhang G.2014. Microbacteriumhydrothermalesp.nov., an actinobacterium isolated from the Indian Ocean.Int J Syst Evol Microbiol.64(Pt10): 3508-3512.
19)Zhang G, Ren H, Wang S, Chen X, Yang Y, Zhang Y, Jiang Y. 2014. Janibacter indicussp. nov., isolated from hydrothermal sediment of the Indian Ocean.Int J Syst Evol Microbiol. 64(Pt 7):2353-2357.
20)Zhang G,Ren H,Chen X,Zhang Y,Yang Y,Wang S,Jiang Y.2014. Sporosarcina siberiensissp. nov., isolated from the East Siberian Sea. Antonie Van Leeuwenhoek. 106(3):489-495.
21)Zhang G, Cao T, Ying J, Yang Y, Ma L. 2014.Diversity and novelty of actinobacteria in Arctic marine sediments. Antonie Van Leeuwenhoek. 105(4):743-754.


授权专利：
1)张改云，王爽，王李娜，周渊. 一株拟无枝酸菌及其应用. 专利号：ZL 6.2
2)王鸿，吴祺豪，陈苏，张改云，李钰金。拟无枝酸菌WP1在制备革兰氏菌活性抑制剂中的应用。专利号：ZL 2.2
3)尹希杰，张改云. 防堵型双路进样针 专利号：9.1
4)张长生，张文军，李苏梅，张海波，张改云，张光涛，朱义广. 一种小单孢菌及利用该菌制备多种抗生素的方法. 专利号：ZL 6
5)张长生，张海波，李苏梅，张改云，张光涛，朱义广，陈瑞东，肖吉，鞠建华. 友菌素的生物合成基因簇及其应用.专利号：ZL5.2
6)杨献文，彭坤，李苏梅，张改云，李洁，林秀萍，刘永宏. 一种新的链霉倍半萜三醇A及其制备方法和应用. 专利号：ZL8.





最新进展：




目前承担的课题：
1.大洋微生物新资源获取及资源库建设（中国大洋矿产资源研究开发协会课题，省部级，子课题负责人，200万元）
2019级研究生培养计划
1.海洋放线菌的获取及多样性研究；
2.基于放线菌基因组信息的新颖天然产物的挖掘；
3.微生物次级代谢产物合成途径关键基因功能研究