个 人 资 料
鄢庆枇 男，福建省永泰县人，汉族，1971年7月11日出生，博士，教授，博士生导师，水产生物医学学术带头人，主要从事水产微生物学研究。
2007年入选福建省高等学校新世纪优秀人才支持计划。
2008年入选福建省百千****才工程。
2009年获福建省青年五四奖章。
2010年被评选为福建省优秀教师。
2012年入选农业部首届水产病害防治专家委员会, 2017年入选农业与农村部第二届水产病害防治专家委员会。
邮箱：yanqp@jmu.edu.cn


主要学习经历：
1989.9——1993.7 于厦门大学海洋学系海洋生物学专业学习，获学士学位。
1993.9——1996.9 于厦门大学环境科学研究中心学习，获硕士学位。
1998.9——2001.11 于厦门大学海洋学系海洋生物学专业学习，获博士学位。

主要工作经历：
1996.10——1999.9 集美大学水产学院，助教。
1999.10——2003.7 集美大学水产学院，讲师。
2003.8——2008.10 集美大学水产学院，副教授。
2008.11——至今 集美大学水产学院， 教授。


主持的主要科研项目：
1． rpoS基因在溶藻弧菌感染过程中的功能及其调控机制研究（国家自然科学基金，**），2017.1-2020.12，74.4万元
2． 海洋渔用疫苗工程技术研究中心（海洋经济区域创新发展示范项目，14PYY050SF03），2014.7-2016.12，1150万元,第二负责人
3． 海水鱼益生菌及海水净化微生物制剂开发与产业化（厦门市海洋经济发展专项资金项目，14CZP032HJ06），2014.7-2017.6，199.85万元
4． 溶藻弧菌对大黄鱼粘附作用的基因调控研究（国家自然科学基金，**），2013.1-2016.12，75万元
5． 海洋药源生物种质资源库建设（海洋经济区域创新发展示范项目子课题，12PYY001SF08），2012.7-2016.12，40万元
6． 应用随机转座诱变技术研究致病性溶藻弧菌的粘附相关基因(福建省****基金，2011J06014)，2011.4-2014.3，30万元
7． 大黄鱼抗菌肽piscidin-like的抗虫特性与作用机制研究（国家自然科学基金子课题，**）, 2012.1-2015.12,15万
8． 海水养殖鱼类原籍饲用益生菌开发（厦门市科技计划项目，3502Z**）,2012.12-2014.12,15万元
9． 水产品中大肠杆菌快速定量检测规程制定（厦门市海洋与渔业局科技项目,201357），2013.1-2014.6,20万元
10． 海洋环境主要病原微生物现场监测的免疫磁珠液相芯片系统（国家863计划项目，2007AA09Z115），2007－2010，99万元
11． 溶藻弧菌对大黄鱼黏液黏附作用研究，福建省高等学校新世纪优秀人才支持计划，2008-2010，30万元
12． 海洋环境大肠杆菌酶荧光快速检测（国家863计划项目，2002AA639600），2002－2004，20万元
13． 海洋环境主要致病菌检测免疫蛋白阵列船载系统（国家863计划项目，2001AA635070），2001-2005，200万元，副组长


近年来发表的主要学术论文（*为通讯作者）：
1． Lixing Huang, Yanfei Zuo, Qingling Jiang, Yongquan Su, Yingxue Qin, Xiaojin Xu, Lingmin Zhao, Qingpi Yan*. A metabolomic investigation into the temperature-dependent virulence of Pseudomonas plecoglossicida from large yellow croaker (Pseudosciaena crocea). Journal of Fish Diseases. 2019,
2． Songlin Guo, Linlin Hu, Jianjun Feng, Peng Lin, Le He, Qingpi Yan*. Immunogenicity of a bivalent protein as a vaccine against Edwardsiella anguillarum and Vibrio vulnificus in Japanese eel (Anguilla japonica). MicrobiologyOpen. 2019
3． Yujia Sun, Gang Luo, Lingmin Zhao, Lixing Huang, Yingxue Qin, Yongquan Su, Qingpi Yan*. Integration of RNAi and RNA-seq reveals the immune responses of Epinephelus coioides to sigX gene of Pseudomonas plecoglossicida. Front. Immunol. 9:1624.doi: 10.3389/fimmu.2018.01624
4． Beibei Zhang, Gang Luo, Lingmin Zhao, Lixing Huang, Yingxue Qin, Yongquan Su, Qingpi Yan*. Integration of RNAi and RNA-seq uncovers the immune responses of Epinephelus coioides to L321_RS19110 gene of Pseudomonas plecoglossicida. Fish & Shellfish Immunology, 2018, 81:121-129.
5． Lixing Huang, Wenjia Liu, Qingling Jiang, Yanfei Zuo, Yongquan Su, Lingmin Zhao, Yingxue Qin, Qingpi Yan*. Integration of transcriptomic and proteomic approaches reveals the temperature-dependent virulence of Pseudomonas plecoglossicida. Frontiers in Cellular and Infection Microbiology, 2018, 8:207. doi: 10.3389/fcimb.2018.00207
6． Huang L, Xu W, Su Y, Zhao L, Yan Q*. Regulatory role of the RstB-RstA system in adhesion, biofilm production, motility, and hemolysis. MicrobiologyOpen. 2018;e599. https://doi.org/10.1002/mbo3.599
7． Lixing Huang, Lingmin Zhao, Yongquan Su, Qingpi Yan*. Sequencing the Genome of Pseudomonas plecoglossicida Strain NZBD9. Genome Announcements. 2018, 6(4):e01412-17.
8． Xu, X., Huang, L., Su, Y., Yan, Q*.The Complete Genome Sequence reveals virulence factors of Vibrio aestuarianus W-40. MicrobiologyOpen.2018,e568
9． Guo, L., Huang, L., Su, Y., Qin, Y., Zhao, L., Yan, Q*. secA, secD, secF, yajC and yidC contribute to the adhesion regulation of Vibrio alginolyticus. MicrobiologyOpen.2018,e551
10． Huang, L., Wang, L., Lin, X., Su, Y., Qin, Y., Kong, W., ... & Yan, Q*. mcp, aer, cheB, and cheV contribute to the regulation of Vibrio alginolyticus (ND-01) adhesion under gradients of environmental factors. MicrobiologyOpen.2017,e517
11． Liu, W., Huang, L., Su, Y., Qin, Y., Zhao, L., & Yan, Q*. Contributions of the oligopeptide permeases in multistep of Vibrio alginolyticus pathogenesis. MicrobiologyOpen. 2017, e511
12． Cong, M., Jiang, Q., Xu, X., Huang, L., Su, Y., & Yan, Q*. The complete genome sequence of Exiguobacterium arabatum W‐01 reveals potential probiotic functions. MicrobiologyOpen. 2017, e496
13． Jiang, Q., Chen, W., Qin, Y., Huang, L., Xu, X., Zhao, L., Yan, Q*. AcuC, a histone deacetylase, contributes to the pathogenicity of Aeromonas hydrophila. MicrobiologyOpen. 2017, e468
14． Lin, G., Chen, W., Su, Y., Qin, Y., Huang, L., Yan, Q*. Ribose operon repressor (RbsR) contributes to the adhesion of Aeromonas hydrophila to Anguilla japonica mucus. MicrobiologyOpen. 2017, 00:1-9
15． Gang Luo, Lixing Huang, Yongquan Su, Yingxue Qin, Xiaojin Xu, Lingmin Zhao, Qingpi Yan*, flrA, flrB, and flrC regulate adhesion by controlling the expression of critical virulence genes in Vibrio alginolyticus. Emerging Microbes and Infections, 2016,5, e85.
16． Yingxue Qin, Guifang Lin, Wenbo Chen, Xiaojin Xu, Qingpi Yan*, Flagellar motility is necessary for Aeromonas hydrophila adhesion. Microbial Pathogenesis. 2016.98:160-166.
17． Lixing Huang, Jiao Hu, Yongquan Su, Yingxue Qin, Wendi Kong, Lingmin Zhao, Ying Ma, Xiaojin Xu, Mao Lin, Jiang Zheng, Qingpi Yan*, Genome-wide detection of predicted non-coding RNAs related to the adhesion process in Vibrio alginolyticus using high-throughput sequencing. Frontiers in Microbiology, 2016, 7, article 619: 1-10
18． Lixing Huang, Li Huang, Qingpi Yan*, Yingxue Qin, Ying Ma, Mao Lin, Xiaojin Xu, Jiang Zheng. The TCA Pathway is an Important Player in the Regulatory Network Governing Vibrio alginolyticus Adhesion Under Adversity. Frontiers in Microbiology, 2016, 7, article 40: 1-13
19． Lu Wang, Lixing Huang, Yongquan Su, Yingxue Qin, Wendi Kong, Ying Ma, Xiaojin Xu, Mao Lin, Qingpi Yan*. Involvement of the flagellar assembly pathway in Vibrio alginolyticus adhesion under environmental stresses. Frontiers in Cellular and Infection Microbiology, 2015, 5, article 59: 1-9.
20． Lixing Huang, JiaoHu, YongquanSu, YingxueQin, WendiKong, YingMa, Xiaojin Xu, MaoLin and Qingpi Yan*. Identification and characterization of three Vibrio alginolyticus non-coding RNAs involved in adhesion, chemotaxis, and motility processes. Frontiers in Cellular and Infection Microbiology, 2015, 5, article 56: 1-13.
21． Li Huang, Yingxue Qin, Qingpi Yan*, Guifang Lin, Lixing Huang, Bei Huang, and Wenshu Huang. MinD plays an important role in Aeromonas hydrophila adherence to Anguilla japonica mucus. Gene. 565(2015)275-281.
22． Wendi Kong, Lixing Huang, Yongquan Su, Yingxue Qin, Ying Ma, Xiaojin Xu, Mao Lin, Jiang Zheng,Qingpi Yan*. Investigation of possible molecular mechanisms underlying the regulation of adhesion in Vibrio alginolyticus with comparative transcriptome analysis. Antonie van Leeuwenhoek. 2015, 107(5):1197-1206.
23． X. Jiang, Y.X. Qin, G.F. Lin, L. Huang, B. Huang, W.S. Huang, Q.P. Yan*. FlgN plays important roles in the adhesion of Aeromonas hydrophila to host mucus. Genetics and Molecular Research. 2015, 14 (2): 6376 - 6386.
24． X.J. Xu, B.H. Sang, W.B. Chen, Q.P. Yan*, Z.Y. Xiong, J.B. Su, W.Z. Zou. Intracellular survival of virulence and low-virulence strains of Vibrio parahaemolyticus in Epinephelus awoara macrophages and peripheral leukocytes. Genetics and Molecular Research. 2015, 14 (1): 706 - 718.
25． Yingxue Qin, Guifang Lin, Wenbo Chen, Bei Huang, Wenshu Huang, Qingpi Yan*. Flagellar motility contributes to the invasion and survival of Aeromonas hydrophila in Anguilla japonica macrophages. Fish & Shellfish Immunology, 2014, 39:273-279.
26． Y.X. Qin, Q.P. Yan*, X.X. Mao, Z. Chen, Y.Q Su. Role of MshQ in MSHA pili biosynthesis and biofilm formation of Aeromonas hydrophila. Genetics and Molecular Research. 2014, 13(4):8982-8996.
27． Qin Yingxue, Yan Qingpi*, Su Yongquan, Li Haiping, Zou Wenzheng.Disruption of Chemotaxis related Genes Affects Multiple Cellular Processes and the Virulence of Pathogenic Vibrio harveyi. Acta Oceanologica Sinica，2013, 32(8):55-60.
28． Wenbo Chen, Yinxue Qin, Xiaojin Xu, Ying Ma, Zhen Chen, Yongquan Su and Qingpi Yan*. Effects of NMMA and catalase on intracellular survival of Vibrio alginolyticus in macrophages of large yellow croaker Pseudosciaena crocea. African Journal of Microbiology Research. 2012,6(12), 2941-2948.
29． Zhang J. J., Li S. Z., Tulake K. , Yan Q. P*., Li W. J. The effects of extenders and sperm-egg ratios on fertilizing ability of cryopreserved testicular sperm of northern pike (Esox lucius L.). Journal of Applied Ichthyology. 27 (2011), 1037–1040.
30． YAN Qingpi, ZHAO Minhui, WANG Xiaolu, ZOU Wenzheng, CHEN Changsheng. Adhesion mechanisms of Vibrio fluvialis to skin mucus of Epinephelus awoara. Chinese Journal of Oceanology and Limnology.2010,28(2):260-266.
31． Qin Yingxue,Su Yongquan,Yan Qingpi*, Wang Shifeng. Immunogenicity and protective efficacy of Vibrio harveyi pcFlaA DNA vaccine in Epinephelus awoara. Chinese Journal of Oceanology and Limnology. 2009, 27(4):769-774.
32． Junjie Zhang, Qingpi Yan*, Rongxing Ji, Wenzheng Zou，Guojun Guo. Isolation and characterization of a hepcidin peptide from the head kidney of Large yellow croaker, Pseudosciaena crocea. Fish and shellfish immunology. 2009,26:864-870.
33． YAN Qingpi, ZHANG Junjie, ZOU Wenzheng, CHEN Qiang, ZHUANG Zhixia, WANG Xiaoru. Immune response of Pseudosciaena crocea to the injection of Vibrio alginolyticus. Chinese Journal of Oceanology and Limnology．2009,27(1):86-92.
34． ZHANG Junjie, ZOU Wenzheng, YAN Qingpi*. Non-specific immune response of bullfrog, Rana catesbeiana, to intraperitoneally injection of the bacterium Aeromonas hydrophila. Chinese Journal of Oceanology and Limnology．2008,26(3):248-255.
35． Qiang Chen, Qingpi Yan*, Kejuan Wang, Wenzheng Zou, Zhixia Zhuang, Xiaoru Wang. Portal of entry for pathogenic Vibrio alginolyticus into Pseudosciaene crocea and characteristic of bacterial adhesion to the mucus. Disease of Aquatic Organism. 2008,80:181-188.
36． Yi Jiabo, Chen Qiang，Zou Wenzheng，Yan Qingpi*，Zhuang Zhixia，Wang Xiaoru.Starvation Effects on Pathogenic Vibrio alginolyticus in Natural Seawater. ACTA Oceanologica Sinica.2008,27(4):120-129.
37． Qing-Pi Yan, Qiang Chen, Shen Ma, Zhi-Xia Zhuang, Xiao-Ru Wang. Characteristics of adherence of pathogenic Vibrio alginolyticus to the intestinal mucus of Large yellow croakers (Pseudosciaena crocea). Aquaculture. 2007, 269:21-30.
38． Chen Qiang, Yan Qingpi*, Ma Shen, Zhuang Zhixia, Wang Xiaoru. Adhesion of pathogenic Vibrio alginolyticus to the gill mucus of Pseudosciaena crocea. ACTA Oceanologica Sinica.2007, 26(3):101-109.