基本信息：
刘丹，副教授，硕士生导师（可招收学硕与专硕研究生）
邮箱：liudan@hqu.edu.cn


研究兴趣：
微流控生物分析、即时检测、纳米生物医学、器官芯片


教育经历：
理学博士（厦门大学化学系化学生物学专业2014-2017）
理学硕士（湖南大学生物技术系生物化学与分子生物学专业2007-2010）
理学学士（贵州大学生物技术系生物科学专业2003-2007）


研究工作经历：
副教授（华侨大学 2020.12-至今）
讲师（华侨大学 2018-2020）
助理研究员（厦门大学附属成功医院 2017-2018）
研究实习员、助理研究员（厦门大学附属成功医院 2010-2014）


主要代表论文：
1)Liu, Dan^*;Shen, Haicong; Zhang, Yuqian; Shen, Danyu; Zhu, Mingyang; Song, Yanling; Zhu, Zhi; Yang, Chaoyong^*; A microfluidic-integrated lateral flow recombinase polymerase amplification (MI-IF-RPA) assay for rapid COVID-19 detection. Lab on a Chip,2021, https://doi.org/10.1039/D0LC01222J.
2)Liu, Dan;Zhang, Yuqian; Zhu, Mingyang; Yu, Zongzhong; Ma, Xiaoming; Song, Yanling; Zhou, Shufeng^*; Yang, Chaoyong^*; Microfluidic-integrated multicolor immunosensor for visual detection of HIV-1 p24 antigen with the naked eye, Analytical Chemistry, 2020, 92 (17), 11826-11833.
3)Liu Dan^*; Zhu, Mingyang; Zhang, Yuqian; Diao, Yong; Crossing the blood-brain barrier with AAV vectors. Metabolic Brain Disease,2021, 36 (1), 45-52.
4)Liu Dan^*; Wang Junxia; Wu Lingling; Huang Yishun; Zhang Yuqian; Zhu Mingyang; Wang Yang; Zhu Zhi^*; Yang Chaoyong; Trends in miniaturized biosensors for point-of-care testing, TrAC Trends in Analytical Chemistry, 2020,122:115701.
5)Liu Dan^*; Liu Fang; Huang Yishun; Song Yanling; Zhu Zhi; Zhou Shu-feng; Yang Chaoyong^*; Catalase-linked immunosorbent pressure assay for portable quantitative analysis, Analyst, 2019,144 (14): 4188-4193.
6)Liu Dan; Tian Tian; Chen Xiaofeng; Lei Zhichao; Song Yanling; Shi Yuanzhi; Ji Tianhai; Zhu Zhi; Yang Liu; Yang Chaoyong^*; Gas-generating reactions for point-of-care testing, Analyst, 2018,143 (6): 1294-1304.
7)Tao Qian; Wu Xinyi; Lin Qingyuan; Zheng Haiyan; Yang Wensheng; Liu Dan^*; Yang Chaoyong James; Ji Tianhai^*; Portable detection of serum HER-2 in breast cancer by a pressure-based platform, Analytical and bioanalytical chemistry, 2018,410 (28): 7489-7498.
8)Liu Dan; Li Xingrui; Zhou Junkai; Liu Shibo; Tian Tian; Song Yanling; Zhu Zhi; Zhou Leiji; Ji Tianhai; Yang Chaoyong^*; A fully integrated distance readout ELISA-Chip for point-of-care testing with sample-in-answer-out capability, Biosensors and Bioelectronics, 2017,96: 332-338.
9)Liu Dan; Jia Shasha; Zhang Huimin; Ma Yanli; Guan Zhichao; Li Jiuxing; Zhu Zhi^*; Ji Tianhai; Yang Chaoyong James^*; Integrating target-responsive hydrogel with pressuremeter readout enables simple, sensitive, user-friendly, quantitative point-of-care testing, ACS Applied Materials & Interfaces, 2017,9 (27): 22252-22258.
10)Ji Tianhai^#;Liu Dan^#; Liu Fang; Li Jiuxing; Ruan Qingyu; Song Yanling; Tian Tian; Zhu Zhi; Zhou Leiji; Lin Hui^*; Chaoyong Yang; Dong Wang^*; A pressure-based bioassay for the rapid, portable and quantitative detection of C-reactive protein, Chemical Communications, 2016, 52 (54): 8452-8454.
11)Zhu Zhi^#; Guan Zhichao^#; Liu Dan^#; Jia Shasha^#; Li Jiuxing; Lei Zhichao; Lin Shuichao; Ji Tianhai; Tian Zhongqun; Yang Chaoyong James^*; Translating molecular recognition into a pressure signal to enable rapid, sensitive, and portable biomedical analysis,Angewandte Chemie International Edition, 2015,54 (36): 10448-10453.
12)Liu Dan; Lin Bingqian; Shao Wei; Zhu Zhi; Ji Tianhai^*; Yang Chaoyong^*; In vitro and in vivo studies on the transport of PEGylated silica nanoparticles across the blood–brain barrier, ACS applied materials & interfaces, 2014,6 (3): 2131-2136.
13)Liu Dan; He Xiaoxiao^*; Wang Kemin^*; He Chunmei; Shi Hui; Jian Lixin; Biocompatible silica nanoparticles?insulin conjugates for mesenchymal stem cell adipogenic differentiation, Bioconjugate chemistry, 2010,21 (9): 1673-1684.


主持课题：

1)国家自然科学基金青年科学基金项目(**)：基于功能化二氧化硅载药纳米粒的胶质瘤靶向治疗与成像研究。
2)化学生物传感与计量学国家重点实验室开放基金(**)：仿生器官芯片用于跨血脑屏障 AAV 的筛选及其跨越机理的分析。
3)泉州市科技局项目(2020SY002)：新型冠状病毒（2019-nCoV）现场快速检测试剂研发。