程国林

教授/博导（2017）
高分子系教工党支部书记（2019）
应用化学系系主任（2021）
福建省新世纪优秀人才（2017）
福建省****人才培育计划（2015）
厦门市重点人才（2017）
Group website：http:///www.x-mol.com/groups/glcheng
地址：厦门市集美大道668号泛华科技大楼 B612
邮箱：glcheng@hqu.edu.cn
教育工作经历：
2017-今
教授/博导
华侨大学，材料科学与工程学院

2015-2017
副教授
华侨大学，生物医学学院

2014-2015
访问****
The Scripps Research Institute(合作导师:Jin-quan Yu美国科学院院士)
2011-2014
讲师
华侨大学，生物医学学院

2007-2011
博士
清华大学, 化学系

2005-2007
硕士
浙江大学, 材化学院

2001-2005
本科
东北石油大学, 化学化工学院

研究兴趣：

羰基与亚胺化学；碳碳键断裂与重组；药物中间体的合成
科研基金：
3). 2021-2024 国家自然科学基金面上项目 (**)，在研
3). 2017-2020 国家自然科学基金面上项目(**)，在研
2). 2013-2015 国家自然科学基金青年项目(**)，已结题
1). 2013-2015 福建省自然科学基金面上项目(2013J01050)，已结题
课题组成员：
2021年 拟招收调剂硕士研究生4名，申请考核制博士研究生2名。
2020级 张雨青
2019级 田青于
2018级 陈燕惠（一等奖学金）、赵泽民、巴聃（一等奖学金）、吕薇薇（两次国家奖学金）
2017级 文思（一等奖学金）、刘景（一等奖学金）
2016级 余佳（国家奖学金）、葛百潞（一等奖学金）
2015级 肖上运

2014级 朱瑞丰（国家奖学金）、薛露露
2013级 翁云翔（清华大学博/福师大副教授）
Publications:
代表作（第一或通讯）：Nat. Commun. 1篇；J. Am. Chem. Soc. 2篇；Angew. Chem. Int. Ed. 2篇。


61.Chen, Y.; Lv, W.; Ba, D.; Wen S.; Cheng, G.* Palladium-Catalyzed Chemoselective Synthesis of 2-Aminocinnamyl Esters via Sequential Amination and Olefination of Aryl Iodides. J. Org. Chem. 2020, 85, 13280-13289 (SCI 中科院 二区)
[Link]



60.Lv, W.; Liu S.; Chen, Y.; Wen S.; Lan Y.;* Cheng, G.* Palladium-Catalyzed Intermolecular trans-Selective Carbofunctionalization of Internal Alkynes to Highly Functionalized Alkenes. ACS. Catal. 2020, 10, 10516–10522.(SCI 中科院 一区)
[Link]


Highlighted by Synfacts: https://doi.org/10.1055/s-
Highlighted by X-Mol: https://www.x-mol.com/news/466165



59.Zeng L.; Xu J.; Zhang D.; Yan Zh.; Cheng G.; Rao W.; Gao L.*Catalytic Enantioselective [2+2] Cycloaddition of α-Halo Acroleins: Construction of Cyclobutanes Containing Two Tetrasubstituted Stereocenters.Angew. Chem., Int. Ed. 2020, accepted(SCI 中科院 一区)

[Link]


58. Lv, W.; Chen, Y.;Wen S.;Ba, D.;Cheng, G.* Modular and Stereoselective Synthesis of C-Aryl Glycosides via Catellani Reaction. J. Am. Chem. Soc. 2020,142, 14864–14870.(SCI 中科院 一区)

[Link]



Highlighted by Synfacts: https://doi.org/10.1055/s-
Highlighted by X-Mol: https://www.x-mol.com/news/463918


57. Ba, D.; Wen S.; Chen, Y.; Lv, W.; Cheng, G.*Rhodium(II)-catalyzed multicomponent assembly of α,α,α-trisubstituted esters via formal insertion of O–C(sp3)–C(sp2) into C–C bonds. Nat. Commun. 2020,11, 4219. (SCI 中科院 一区)
[Link]





Highlighted by Synfacts: https://doi.org/10.1055/s-
Highlighted by X-Mol: https://www.x-mol.com/news/466051
56. Liu J. Ba, D.; Chen, Y.;Wen S.; Cheng, G.* Tandem reaction to 3-(2-quinolyl) chromones from ynones and quinoline N-oxides under transition metal- and additive-free conditions.Chem. Commun., 2020, 56,4078-4081. (SCI 中科院 二区)
[Link]




55. Wen S.;Chen, Y.;Ba, D.; Lv, W.; Cheng, G.* Ruthenium(II)-Catalyzed Construction of Isocoumarins via Dual C?H/C?C Activation of Sulfoxonium Ylides.J. Org. Chem. 2020, 85,1216-1223. (SCI 中科院 二区)

[Link]







54. Ge, B; Peng, Y.; Liu, J.; Wen S.; Peng, C.; Cheng, G.* Acid-Promoted Cleavage of the C?C Double Bond of N-(2-Hydroxylphenyl)enaminones for the Synthesis of Benzoxazoles. Tetrahedron. 2020, 76, 130818-130825.(SCI 中科院 三区)
[Link]





53. Liu, J.; Ba, D.; Lv, W.; Chen, Y.; Zhao, Z.; Cheng, G.* Based-promoted Michael addition/Smiles rearrangement/N-arylation cascade：One-step syntheses of 1,2,3-trisubstituted 4-quinolones from ynones and sulfonamides. Adv. Synth. Catal. 2020, 362, 213-223.(SCI 中科院 二区)
[Link]





52. Ba, D.;Chen, Y.; Lv, W.; Chen, Y.; Wen S.; Cheng, G.* Copper-Catalyzed Three-Component Cascade Michael Addition/Heck-Type Alkylation/Annulation: Accessing Fully Substituted 1,3-Dihydro-2H-pyrrol-2-ones.Org. Lett. 2019,21, 8603-8606. (SCI 中科院 一区)

[Link]





51.Lv, W.; Chen, Y.; Zhao, Z.; Wen, S.; Cheng, G.*Palladium-Catalyzed Regioselective Heck Coupling of Alkynes with Aryl Iodides for the Synthesis of Trisubstituted Allenes. Org. Lett. 2019, 21,7795-7798. (SCI 中科院 一区)
[Link]
50.Wen S.; Lv, W.; Ba, D.; Liu, J.; Cheng, G.*Ruthenium(II)-catalyzed chemoselective deacylative annulation of 1,3-diones with sulfoxonium ylides via C–C bond activation.Chem. Sci. 2019, 10,9104-9108. (SCI 中科院 一区)
[Link]






49.Yu, J.; Wen, S.; Ba, D.; Lv, W.; Chen, Y.Cheng, G.*Rhodium(III)-Catalyzed Site-Selective C?H Acylmethylation of 2,2′-Bipyridine-6-carboxamides with Sulfoxonium Ylides.Org. Lett. 2019, 21, 6366-6369. (SCI 中科院 一区)
[Link]





48. Lv, W.; Wen, S.; Liu, J.; Cheng, G.*Palladium-Catalyzed Ortho- C?H Methylation of Benzoic Acids.J. Org. Chem. 2019, 84,9786-9791 (SCI 中科院 二区)
[Link]



47. Lv, W.; Yu, J.; Ge, B.; Wen, S.; Cheng, G.* Palladium-Catalyzed Catellani-Type bis-Silylation and bis-Germanylation of Aryl Iodides and Norbornenes. J. Org. Chem. 2018, 83，12683-12693.(SCI 中科院 二区)
[Link]



46. Ge, B.; Lv W.; Yu J.; Xiao S.; Cheng G.* Base-promoted C–C bond cleavage for the synthesis of 2,3,4-trisubstituted pyrroles from N-propargyl β-enaminones. Org. Chem. Front. 2018, 5, 3103-3107 (SCI 中科院 一区)
[Link]



45. Cheng, G;* Lv, W.; Xue, L. Base-promoted ring-closing carbonyl–allene metathesis for the synthesis of 2,4-disubstituted pyrroles. Green Chem. 2018, 20, 4414-4417. (SCI 中科院 一区).selected as back cover.
[Link]



44. Lv, W.; Wen, S.; Yu, J.; Cheng, G.* Palladium-Catalyzed Ortho-Silylation of Aryl Iodides with Concomitant Arylsilylation of Oxanorbornadiene: Accessing Functionalized (Z)-β-Substituted Vinylsilanes and Their Analogues. Org. Lett. 2018, 20, 4984-4987. (SCI 中科院 一区)
[Link]



43. Yu, J.; Lv, W.; Cheng, G.* Palladium-Catalyzed Site-Selective C?H Arylation of 2,2′-Bipyridine-6-carboxamides via a Rollover Cyclometalation Pathway. Org. Lett. 2018, 20, 4762-4735. (SCI 中科院 一区)
[Link]



42. Zhang,H.; Shen,J.; Cheng,G.; Wu,B.; Cui, X.* Base-Promoted Synthesis of 2,4,6-Triarylpyridines from Enaminones and Chalcones. Asian J. Org. Chem. 2018, 7, 1089 – 1092. (SCI 中科院 三区)
[Link]

41. Weng, Y.; Kuai, C.; Lv, W.; Cheng, G.* Synthesis of 2-Aminopyridines via a Base-Promoted Cascade Reaction of N-Propargyl Enaminones with Formamides. J. Org. Chem. 2018,83, 5002?5008. (SCI 中科院 二区)
[Link]




40. Weng, Y.; Lv, W.; Yu, J.; Ge, B.; Cheng, G.* Preparation of 2,4,5-Trisubstituted Oxazoles through Iodine-Mediated Aerobic Oxidative Cyclization of Enaminones. Org. Lett. 2018, 20, 1853–1856. (SCI 中科院 二区)
[Link]



39. Cheng, G.*; Lv, W.; Kuai C.; Wen S; Xiao S. Base-Promoted Amide Synthesis from Aliphatic Amines and Ynones as Acylation Agents through C–C Bond Cleavage. Chem. Commun., 2018, 54, 1726-1729.(SCI 中科院 二区)
[Link]



Highlighted by Synfacts: https://doi.org/10.1055/s-
38. Zhang H.; Shen J.; Cheng G.; Feng Y.; Cui X. One-Pot Synthesis of Benzo[b][1,4]oxazins via Intramolecular Trapping Iminoenol, Org. Lett. 2018, 20, 664-667. (SCI 中科院 一区)
[Link]



37. Xue, L.; Cheng, G.*; Zhu, R.; Cui, X. *, Acid-Promoted Oxidative Methylenation of 1,3-DicarbonylCompounds with DMSO: Application to the Three-Component Synthesis of Hantzsch-TypePyridines. RSC Adv., 2017, 7, 44009-44012.(SCI 中科院 三区)
[Link]



36. Cheng, G.*; Xue, L.; Weng, Y.; Cui, X. *, Transition-Metal-Free Cascade Approach toward 2?Alkoxy/2-Sulfenylpyridines and Dihydrofuro[2,3?b]pyridines by Trapping In Situ Generated 1,4-Oxazepine. J. Org. Chem. 2017, 82, 9515-9524。(SCI 中科院 二区)
[Link]



35. Cheng, G.;⁺ Wang P.; ⁺ Yu, J.-Q.*, Meta-C?H Arylation and Alkylation of Benzylsulfonamide Enabled by a Pd(II)/Isoquinoline Catalyst. Angew. Chem., Int. Ed. 2017, 56, 8183-8186. (SCI 中科院 一区)
[Link]



34. Ding, Q.; Ye, S.; Cheng, G.; Wang, P.; Farmer, M. E.; Yu, J.-Q.*, Ligand-Enabled meta-Selective C–H Arylation of Nosyl-Protected Phenethylamines, Benzylamines, and 2-Aryl Anilines J. Am. Chem. Soc.2017, 139, 417-425. (SCI 中科院 一区)
[Link]



33. Zhu, R.; Cheng, G.*; Jia, C.; Xue, L.; Cui, X.*, Access to C4-Functionalized Quinolines via Copper-Catalyzed Tandem Annulation of Alkynyl Imines with Diazo Compounds. J. Org. Chem. 2016, 81, 7539-7544. (SCI 中科院 二区)
[Link]



32. Shen, J. H.; Yang, X. F.; Wang, F. Y.; Wang, Y.; Cheng, G.; Cui, X. L.*, Base-mediated regiospecific cascade synthesis of N-(2-pyridyl)pyrroles from N-propargylic beta-enaminones. Rsc Adv. 2016, 6,48905-48909. (SCI 中科院 三区)
[Link]



31. Shen, J. H.; Xue, L. L.; Lin, X.; Cheng, G.; Cui, X.*, The base-promoted synthesis of multisubstituted benzo b 1,4 oxazepines. Chem. Commun. 2016, 52, 3292-3295. (SCI 中科院 二区)
[Link]



30. Shen, J. H.; Wang, X. D.; Lin, X.; Yang, Z. H.; Cheng, G.; Cui, X.*, One-Pot Regiospecific Synthesis of Quinoxalines via a CH2-Extrusion Reaction. Org. Lett. 2016,18 , 1378-1381. (SCI 中科院 一区)
[Link]



29. Cheng, G.; Li, T.-J.; Yu, J.-Q.*, Practical Pd(II)-Catalyzed C-H Alkylation with Epoxides: One-Step Syntheses of 3,4-Dihydroisocoumarins. J. Am. Chem. Soc. 2015,137, 10950-10953. (SCI 中科院 一区)
[Link]



28. Wang, F.; Shen, J.; Cheng, G.; Cui, X.*, Practical access to 1,3,5-triarylbenzenes from chalcones and DMSO. RSC Adv. 2015,5, 73180-73183. (SCI 中科院 三区)
[Link]



27. Shen, J.; Cai, D.; Kuai, C.; Liu, Y.; Wei, M. e.; Cheng, G.; Cui, X.*, Base-Promoted beta-C(sp(3))-H Functionalization of Enaminones: An Approach to Polysubstituted Pyridines. J. Org. Chem. 2015,80, 6584-6589.(SCI 中科院 二区)
[Link]



26. Feng, Y.; Li, Y.; Cheng, G.; Wang, L.; Cui, X.*, Copper-Catalyzed Synthesis of 2-Arylquinazolinones from 2-Arylindoles with Amines or Ammoniums. J. Org. Chem. 2015,80, 7099-7107. (SCI 中科院 二区)
[Link]



25. Cheng, G.*; Weng, Y.; Yang, X.; Cui, X.*, Base-Promoted N-Pyridylation of Heteroarenes Using N-Propargyl Enaminones as Equivalents of Pyridine Scaffolds. Org. Lett. 2015,17, 3790-3793. (SCI 中科院 一区)
[Link]





24. Yang, X.; Cheng, G.*; Shen, J.; Kuai, C.; Cui, X.*, Cleavage of the C-C triple bond of ketoalkynes: synthesis of 4(3H)-quinazolinones. Org. Chem.Front. 2015,2, 366-368. (SCI 中科院 一区)
[Link]





23. Wang, X.; Cheng, G.; Shen, J.; Yang, X.; Wei, M.-e.; Feng, Y.; Cui, X.*, A metal-free synthesis of diaryl-1,2-diketones by C-C triple bond cleavage of alkynones. Org. Chem.Front. 2014,1, 1001-1004. (SCI 中科院 一区)
[Link]



22. Cheng, G.; Zhang, H.; Cui, X., Copper(I)-catalyzed homo-coupling of terminal alkynes at room temperature under solvent and base free conditions using O² as an oxidant. RSC Adv. 2014, 4, 1849-1852. (SCI 中科院 三区)
[Link]



21. Cheng, G.; Zeng, X.; Cui, X., Benzoquinone-Promoted Aerobic Oxidative Hydroxylation of Arylboronic Acids in Water. Synthesis. 2014, 295-300. (SCI 中科院 三区)
[Link]



20. Li, P.; Cheng, G.*; Zhang, H.; Xu, X.; Gao, J.; Cui, X.*, Copper-Catalyzed One-Pot Synthesis of Unsymmetrical Arylurea Derivatives via Tandem Reaction of Diaryliodonium Salts with N-Arylcyanamide.J. Org. Chem. 2014, 79, 8156-8162. (SCI 中科院 二区)
[Link]



19. Feng, Y.; Zhang, H.; Cheng, G.*; Cui, X.,Synthesis of Indole Derivatives via Domino Reactions.Chin. J. Org. Chem. 2014, 34, 1499-1508. (SCI 中科院 三区)
[Link]



18. Wang, X.; Cheng, G.; Cui, X., Tandem synthesis of 3-allyl-chromones from alkynones and allylic alcohols under metal-free conditions. Chem. Commun. 2014, 50, 652-654. (SCI 中科院 二区)
[Link]



17. Gao, Y.; Song, Q.; Cheng, G.; Cui, X.,KI-catalyzed arylation of benzothiazoles from the coupling of aryl aldehydes with benzothiazoles in neat water. Org. Biom. Chem. 2014, 12, 1044-1047. (SCI 中科院 三区)
[Link]




16. Cheng, G.; Zeng, X.; Shen, J.; Wang, X.; Cui, X., A metal-free multicomponent cascade reaction for the regiospecific synthesis of 1,5-disubstituted 1,2,3-triazoles. Angew. Chem., Int. Ed. 2013, 52, 13265-13268. (SCI 中科院 一区)
[Link]



15. Shen, J.; Cheng, G.; Cui, X., "One pot" regiospecific synthesis of polysubstituted pyrroles from benzylamines and ynones under metal free conditions. Chem. Commun. 2013, 49, 10641-10643. (SCI 中科院 二区)
[Link]




14. Shao, C.; Zhang, Q.; Cheng, G.; Cheng, C.; Wang, X.; Hu, Y., Copper(I) Acetate-Catalyzed Cycloaddition between Azomethine Imines and Propiolates under Additive-Free Conditions. Eur. J. Org. Chem. 2013, 6443-6448.(SCI 中科院 三区)
[Link]



13. Cheng, G.; Cui, X., Efficient Approach to 4-Sulfonamidoquinolines via Copper(I)-Catalyzed Cascade Reaction of Sulfonyl Azides with Alkynyl Imines. Org. Lett. 2013, 15, 1480-1483. (SCI 中科院 一区)
[Link]



12. Zeng, X.; Cheng, G.; Shen, J.; Cui, X., Palladium-Catalyzed Oxidative Cross Coupling of N-Tosylhydrazones with Indoles: Synthesis of N-Vinylindoles. Org. Lett. 2013, 15, 3022-3025. (SCI 中科院 一区)
[Link]



11. Cheng, G.; Wang, X.; Bao, H.; Cheng, C.; Liu, N.; Hu, Y., Total Syntheses of (-)-Hanishin, (-)-Longmide B, and (-)-Longmide B Methyl Ester via a Novel Preparation of N-Substituted Pyrrole-2-Carboxylates. Org. Lett. 2012, 14, 1062-1065. (SCI 中科院 一区)
[Link]




10. Shen, J.; Cheng, G.; Cui, X., Domino Reactions Based on Pd-Catalyzed C-H Bond Activation.Prog. Chem.2012, 24, 1324-1336.(SCI 中科院 三区)

9. Wang, Y.; Cheng, G.; Cui, X., Easily Modified Directing Groups for the Palladium-Catalyzed C-H Functionalization. Chinese J. Org. Chem. 2012, 32, 2018-2039. (SCI 中科院 三区)
[Link]





Before Huaqiao University



8. Cheng, G.; Wang, X.; Zhu, R.; Shao, C.; Xu, J.; Hu, Y., Total Synthesis of (-)-Cocaine and (-)-Ferruginine. J. Org. Chem. 2011, 76, 2694-2700.(SCI 中科院 二区)
[Link]



7. Cheng, G.; Wang, X.; Su, D.; Liu, H.; Liu, F.; Hu, Y., Preparation of Enantiopure Substituted Piperidines Containing 2-Alkene or 2-Alkyne Chains: Application to Total Syntheses of Natural Quinolizidine-Alkaloids. J. Org. Chem. 2010, 75, 1911-1916.(SCI 中科院 二区)
[Link]



6. Xu, J.; Wang, X.; Shao, C.; Su, D.; Cheng, G.; Hu, Y., Highly Efficient Synthesis of Phenols by Copper-Catalyzed Oxidative Hydroxylation of Arylboronic Acids at Room Temperature in Water. Org. Lett. 2010, 12, 1964-1967. (SCI 中科院 一区)
[Link]



5. Shao, C.; Cheng, G.; Su, D.; Xu, J.; Wang, X.; Hu, Y., Copper(I) Acetate: A Structurally Simple but Highly Efficient Dinuclear Catalyst for Copper-Catalyzed Azide-Alkyne Cycloaddition. Adv. Synth. Catal. 2010, 352, 1587-1592. (SCI 中科院 二区)
[Link]


4. Liu, H.; Su, D.; Cheng, G.; Xu, J.; Wang, X.; Hu, Y., Enantiopure 2,6-disubstituted piperidines bearing one alkene- or alkyne-containing substituent: preparation and application to total syntheses of indolizidine-alkaloids. Org. Biom. Chem. 2010, 8, 1899-1904. (SCI 中科院 三区)
[Link]



3. Xu, J.; Cheng, G.; Su, D.; Liu, Y.; Wang, X.; Hu, Y., Direct ortho-Arylation of N-Phenacylpyridinium Bromide by Palladium-Catalyzed C-H-Bond Activation. Chem-Eur. J. 2009, 15, 13105-13110.(SCI 中科院 二区)
[Link]




2. Liu, B.; Su, D.; Cheng, G.; Liu, H.; Wang, X.; Hu, Y., An Efficient Method for the Preparation of Versatile Building Blocks: 1-Substituted 2,2-Dimethoxyethylamine Hydrochlorides. Synthesis 2009, 3227-3232. (SCI 中科院 三区)
[Link]



1. Dai, L. (导师); Cheng G.; Wang X.; Chen Y., Synthesis of 2-mercapto-5-methoxyimidazo[4,5-b]pyridine. J. Chem. Ind. Eng. (China), 2007, 58, 656-659. (EI)



授权专利：


1. 程国林， 翁云翔，一种多取代二氢呋喃[2,3-b]吡啶衍生物的制备方法，ZL4.6
2. 程国林， 翁云翔，一种多取代吡啶衍生物的制备方法，CN4.3