刘国东，男，1972年出生，博士，现任美国北达科他州立大学（North Dakota State University）化学与生物化学系副教授，福建农林大学闽江****讲座教授。在Journal of the American Chemistry Society、Analytical Chemistry、 Biosensors and Bioelectronics、Chemical Communications等分析化学领域顶级期刊上发表了SCI论文70余篇，这些论文被SCI期刊他人正面引用1000余次。现为Nano-Bio-Analysis杂志编委，美国化学学会、科学发展协会和电分析化学协会会员并应邀担任“Frontier in Bioscience”, “Analytical Chemistry”, “Journal of American Chemistry Society”，“Electrochemistry Communication”、 “Chemical Communications”、“Electroanalysis”、“Analytical Chimica Acta”、“Journal of Nanoscience and Nanotechnology”、“Analyst” 等杂志审稿人。获得2006和2007年度太平洋西北国家实验室杰出工作奖章，以及2010-2012北达科他州立大学杰出研究奖等。
受教育经历：
2004/10-2006/09 美国Pacific North West National Laboratory 生物分析化学 博士后
2002/01-2004/09 美国New Mexico State University 生物分析化学 博士后
2001/06 湖南大学 生物分析化学 博士学位
1998/07 湖南大学 分析化学 硕士学位
1995/07 湖南师范大学 分析化学 学士学位
研究工作经历：
2013-至今 美国North Dakota State University 副教授
2007-2013 美国North Dakota State University 助理教授
2006-2007 美国Pacific Northwest National Laboratory 研究员
研究方向和领域：
研究领域主要为构建基于纳米材料的生物传感器、生物分析方法和现场检测装置，应用于生物医药中核酸、蛋白质超灵敏检测，食品安全检测，临床即时检测以及环境监测等。
硕士生导师招生学科介绍：
1. 食品科学
2. 农业推广（食品加工与安全领域）
科研项目：
1. “Development of Hand-Held Cancer Biomarker Monitor” (NIH, R21, 5R21CA137703-02)， 项目负责人，2010/09/01-2014/04/30.
2. “Development of Lateral Flow Nucleic Acid Biosensors for the Detection of HPV” (DakotaBio Corp, Industry Research Funds, FAR**)，项目负责人，2012/08/01-2015/02/28.
3. “Conjugates of Quantum Dots and Natural Iron Complexes for Detecting Gram-negative Pathogens and Probing Membrane Transport Mechanisms” (Center of Protease Research NDSU, COBRE Pilot Project, FAR**), 项目负责人，2013/03/01-2014/06/30.
4. “Arrayed Lateral Flow Biosensor for Rapid Molecular Identification of UTI-Related” (Lynntech Inc, SBIR subcontract, 1 R43 AI102357-01), 项目负责人, 2012/09/01-2013/05/31.
5. “A POC Field Test for the Rapid Determination of Folate Insufficiency (SBIR, Phase I)” (Lynntech Inc, SBIR subcontract, 200-2012-M-52272), 项目负责人, 2012/09/01-2013/05/31.
6. “Rapid and Cost-Effective Diagnostic System for Sexually Transmitted Infections” (Lynntech Inc, NIH SBIR subcontract), 项目负责人, 2011/12/01-2012/05/31.
7. “An Integrated Optical DNA Detector for Portable PCR” (Lynntech Inc, NIH SBIR subcontract), 项目负责人, 2010/01/01-2010/05/31.
8. “Innovative Biomonitoring Device for Rapid Diagnosis of Exposure to Nerve Agents” (Pacific Northwest National Laboratory, NIH U01 subcontract), 项目负责人, 2007/01/11-2010/05/30.
9. “North Dakota State University New Faculty Start up” (North Dakota State University, Start-up funds), 项目负责人, 2007/08/01-2009/07/31.
10. “Development of Point-of-Care Nucleic acid Biosensors for Clinical Diagnosis” (NIH INBRE Lynntech Inc, Seed grant), 项目负责人, 2008/09/01-2009/04/30.
11. “Integrated Nucleic acid and Protein Biosensors for Cancer Early Diagnosis” (Center of Proteases Research NDSU, CPR Seed grant), 项目负责人, 2009/01/01-2009/05/30.
12. “Portable Analyzer for on-site Monitoring of worker Exposure to Toxic Metal” (Pacific Northwest National Laboratory, NIH R21 Sub-contract), 项目负责人, 2008/01-2008/07.
近年发表的学术论文:
1. Qiu, W.; Xu, H.; Takalkar, S.; Gurung, A. S.; Liu, B.; Zheng, Y.; Guo, Z.; Baloda, M.; Baryeh, K.; Liu, G.* “Carbon nanotube-based lateral flow biosensor for sensitive and rapid detection of DNA sequence.” Biosensors and Bioelectronics 2015, 64, 367-372.
2. Xu, H.; Chen, J.; Birrenkott, J.; Zhao, J. X.; Takalkar, S.; Baryeh, K.; Liu, G.* “Gold-nanoparticle-decorated silica nanorods for sensitive visual detection of proteins. “ Analytical Chemistry 2014, 86, 7351-7359.
3. Gao, X.; Xu, H.; Baloda,M.^; Gurung,A. S.; Xu, L.; Wang, T.;Zhang, X.;Liu, G.* “Visual Detection of microRNA with Lateral Flow Nucleic Acid Biosensor.” Biosensor and Bioelectronics 2014, 54, 578-584.
4. Shen, G.; Xu, H.; Gurung, A. S.; Yang, Y.; Liu, G. * “Lateral Flow Immunoassay with the Signal Enhanced by Gold Nanoparticle Aggregates Based on Polyamidoamine Dendrimer.” Analytical Sciences, 2013, 29, 799-804.
5. Xu, L.; Wang, S.; Dong, H.; Liu, G.; Wen, Y.; Wang S.; Zhang, X. “Fractal gold modified electrode for ultrasensitive thrombin detection.” Nanoscale 2012 4, 3786- 3790.
6. He, Y.; Zhang, X.; Zhang, S.; Kris, K. L.; Man, F. C.; Kawde, A.; Liu, G.* “Visual detection of single-base mismatches in DNA using hairpin oligonucleotide with double- target DNA binding sequences and gold nanoparticles.” Biosensor and Bioelectronics 2012, 34, 37-43.
7. He, Y.; Zeng, K.; Zhang S.; Gurung, A. S.; Baloda, M.; Zhang, X.; Liu, G.* “Visual detection of genemutations based on isothermal strand-displacement polymerase reaction and lateral flow strip.”Biosensor and Bioelectronics 2012, 31(1), 310-315.
8. He, Y.; Zhang, X.; Zeng, K.; Zhang, X.; Baloda, M.; Gurung, A. S.; Liu G.* “Visual detection of Hg²? in queou solution using gold nanoparticles and thymine-rich hairpin DNA probes.” Biosensor and Bioelectronics 2011, 26(11), 4464-4470.
9. He, Y.; Zhang, S.; Zhang, X.; Baloda, M.; Gurung, A. S.; Xu, H.; Zhang, X.; Liu, G.* “Ultrasensitive nucleic acid biosensor based on enzyme-gold nanoparticle dual label and lateral flow strip biosensor.” Biosensors and Bioelectronics 2011, 26(5), 2018-2024.
10. Fang, Z.; Huang, J.;Lie, P.; Xiao, Z.; Ouyang, C.; Wu, Q.; Wu, Y.; Liu, G.*; Zeng, L. “Lateral flow nucleic acid biosensor for Cu2+ detection in aqueous solution with high sensitivity and selectivity.” Chemical Communications 2010, 46(47), 9043-9045.
11. He, Y.; Zeng, K.; Gurung, A.; Baloda, M.; Xu, H.; Zhang, X.; Liu, G.* “Visual detection of single-nucleotide polymorphism with hairpin oligonucleotide-functionalized gold nanoparticles.” Analytical Chemistry 2010, 82(17), 7169-7177.
12. He, Y.; Zeng, K.; Zhang, X.; Gurung, A.; Baloda, M.; Xu, H.; Liu, G.* “Ultrasensitive electrochemical detection of nucleic acid based on the isothermal strand-displacement polymerase reaction and enzyme dual amplification.” Electrochemistry Communications, 2010, 12, 985-988.
13. Zhao, L.; He, Y.; Mao, X.; Sun, Y.; Zhang, X.; Li, C.; Liu, G.* “Electrochemical assay of active prostate-specific antigen (PSA) using ferrocene-functionalized peptide probes.” Electrochemistry Communications 2010, 12(3), 471-474.





　
　

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