李刚
学术学位硕士生导师

教授
**


ganglicqmu@126.com

第一临床学院





学科信息


个人简介
李刚,医学博士,主任医师,教授，硕士研究生导师。1983-1989华西医科大学临床医学院医学专业六年制，医学学士学位。1992-1995，1995-1998重庆医科大学研究生学院内科学心血管病专业，医学硕士学位，医学博士学位。1989-2004在重庆医科大学附属第二医院心内科历任住院医师，主治医师和副主任医师。2004至今在重庆医科大学附属第一医院老年病科/全科医疗科历任副主任医师，主任医师，教授。其中，2000-2004美国华盛顿大学（Washington University in St. Louis），德国柏林自由大学(Free University of Berlin)和芬兰东芬兰大学(University of Eastern Finland Kuopio campus),访问****，心血管病研究。2005起任医学硕士研究生导师。2008被评为重庆市老年医学学术技术带头人后备人选。擅长高血压，高血脂，冠心病，心衰，心律失常等心血管疾病的诊断和治疗。承担临床医学本科生，留学生，5+3本硕连读生老年医学，老年临床，全科医学和临床医学导论的中文和全英文大课教学和临床实践教学。重庆市科委及卫生局科研基金资助下在Acta Cardiologica Sinica, Experimental & Clinical Cardiology, International Journal of Gerontology,Clinical Intervention in Aging,Echocardiography, Journal of the Chinese Medical Association, Cell Biochemistry & Function, Cell Biology International, Clinical and Experimental Pharmacology and Physiology, Medical Education Online, Scientific Reports等专业医学期刊上发表通讯作者或第一作者SCIE论著10多篇。Biomedicine & Pharmacotherapy, Clinical and Experimental Pharmacology and Physiology, Journal of Cellular Biochemistry, Cellular Signaling, Journal of Biological Regulators and Homeostatic Agents, Medical Science Monitor, BMJ Open, Disease Markers, Metabolic Syndrom and Obesity Targets and Therapy, Archives of Medical Research等SCIE医学期刊论文同行评审专家。


论文情况
Zhang J, Li G, et al. Low body weight is associated with reduced left ventricular mass in Chinese elderly with severe COPD. Sci Rep 2021; 11(1): 13074. SCIE

Song X, Li G, et al. Glomerular filtration dysfunction is associated with cardiac remodeling in menopause diabetic Chinese women. Clin Interv Aging 2021; 16: 603-609. SCIE
Liu C, Li G, et al. Overweight and obesity are associated with cardiac adverse structure remodeling in Chinese elderly with hypertension. 2019; 9(1): 17896. SCIE
Li G, et al. Orderly display of limb leads ECGs raise Chinese intern's diagnostic accuracy when determining frontal plane QRS axis. Med Educ Online 2019; 24(1): **. SSCI
Yand D, Zhang L, Zhang Z, Hu S, Hu Y, Laukkanen JA, Li G. Silencing of C3G increases cardiomyocyte survival inhibition apoptosis via regulation of p-ERK1/2 and Bax. Clin Exp Pharmacol Physiol 2019; 46: 237-245. SCIE
Zhao Q, Lakkanen JA, Li Q, Li G. Body mass index is associated with type 2 diabetes mellitus in Chinese elderly. Clin Interv Aging 2017; 12: 745-752. SCIE
Peng J, Lakkanen JA, Zhao Q, Wang L, Zhang X, Li G. Association of left atrial enlargement with ventricular remodeling in Chinese hypertensive elderly. Echocardiography 2017; 34(4): 491-495. SCIE
Zhang Z, Yang D, Fu Y, Zhang L, Zhao Q, Li G. Knockdown of CrkL by shRNA deteriorates hypoxia/reoxygenation-induced H9C2 cardiomyocyte apoptosis and survival inhibition via Bax and p-ERK1/2. Cell Biochem Funct 2015; 33(2): 80-88. SCIE
Zhang X, Li G, et al. C3G overexpression promotes the survival of rat-derived H9C2 cardiomyocytes by p-ERK1/2. Cell Biol Int 2013; 37(10): 1106-1113. SCIE
Zhou J, Li G, et al. Effects of low-dose hydroxychloroquine on expression of phosphorylated Akt and p53 proteins and cardiomyocyte apoptosis in peri-infarct myocardium in rats. Exp Clin Cardiol 2013; 18(2): e95-98. SCIE
Liu XL, Li G, et al. Increased expression of Dock180 protein in the noninfarcted myocardium in rats. J Chin Med Assoc 2013; 76(3): 164-168. SCIE
Li G, et al. Plasma uric acid is associated with postinfarction cardiac remodeling in elderly old myocardial infarction. Int J Gerontol 2012; 6(3): 174-176. SCIE
Mu Y, Li G, et al. Up-regulation of phosphorylated ATM/ATR substrate / Akt expression by phenylephrine in peri-infarct myocardium in rats. Acta Cardiol Sin 2011; 27(3): 182-188. SCIE
Li G, et al. Plasma hemoglobin concentration was related to estimated glomerular filtration rate in elderly patients with ischemic cardiomyopathy. J Geriatr Cardiol 2008; 5(3): 150-154.
Li G, et al. Serum concentrations of hyaluronic acid, procollagen type III NH2-terminal peptide and laminin in patients with chronic congestive heart failure. Chin Med Sci J 2006; 21(3): 175-178.







研究方向
高血压，冠心病, 缺血性心肌病，心脏重塑，心力衰竭，心律失常，糖尿病等老年病发病机制