徐绣宇
学术学位硕士生导师

副主任技师



xuxiuyu85@126.com

第一临床学院





学科信息


个人简介
徐绣宇，女，医学博士，副主任技师，硕士研究生导师。中华医学会细菌感染与耐药防治分会青年学组委员，重庆市妇幼卫生学会检验医学专业委员会委员，Infection and Drug Resistance等SCI杂志审稿人。主要从事临床微生物检验工作，主要研究方向为常见院内感染病原菌的致病机制研究、院内感染多重耐药病原菌的快速检测和耐药机制及分子流行病学特征研究。先后主持国家自然科学基金青年基金项目1项（肺炎链球菌疫苗SPY1的一种免疫保护机制：TGF-β信号通路介导Treg细胞参与保护性免疫，基金号：**），重庆市科委面上项目2项（肠道菌群紊乱负向调控IL-22-REG3β促高毒力肺炎克雷伯菌肝脓肿的机制研究，基金号：cstc2020jcyj-msxmX0199）（肺炎链球菌疫苗SPY1诱导Treg细胞参与保护性免疫的作用机制研究，基金号：cstc2015jcyjA10102），重庆医科大学附属第一医院医学检验科学科培育基金项目1项。先后参与国家自然科学基金研究项目7项。以第一作者或通讯作者发表SCI论文6篇。


科研项目

国家自然科学基金委员会，青年基金项目，**，肺炎链球菌疫苗SPY1的一种免疫保护机制：TGF-β信号通路介导Treg细胞参与保护性免疫， 2016.01-2018.12，24万元，已结题，主持
重庆市科委，自然科学基金面上项目，cstc2020jcyj-msxmX0199，肠道菌群紊乱负向调控IL-22-REG3β促高毒力肺炎克雷伯菌肝脓肿的机制研究，2020.07-2023.06，5万元，在研，主持
重庆市科委，自然科学基金项目，cstc2015jcyjA10102，肺炎链球菌疫苗SPY1诱导Treg细胞参与保护性免疫的作用机制研究，2015.08-2018.07，5万元，已结题，主持


论文情况

Xiuyu Xu, Qiang Wei, Zhu Wang, Jie Yan, Huijuan Wang, Yun Xia*. Inactivation of clinically frequently used antimicrobial agents by BacT/ALERT FAN Plus and BACTEC aerobic and anaerobic culture media in simulated blood cultures: first comparative evaluation in China mainland, Infect Drug Resist, 2021, 14:163-172.
WeiQiang, SunJide, WangZhu, YanLi, ZhangChuanming, XuXiuyu*. Evaluation of modified rapid carbapenem inactivation method (mrCIM) combined with rapid EDTA-modified carbapenem inactivation method (reCIM) to detect carbapenemase and distinguish metallo-carbapenemase in Enterobacteriaceae within four hours, Infect Drug Resist, 2020,13: 1919-1927.
SunJide, DuLi, YanLi*, DaiWei, WangZhu,Xu Xiuyu; Eight-year surveillance of uropathogenic Escherichia coli in southwest China, Infect Drug Resist, 2020, 13: 1197-1202.
Liao Hongyi#; Peng Xiaoqiong#; Gan Lingling; Feng Jiafu, Gao Yue, Yang Shenghui, Hu Xuexue, Zhang Liping, Yin Yibing, Wang Hong, Xu Xiuyu*; Protective regulatory T cell immune response induced by intranasal immunization with the live-attenuated pneumococcal vaccine SPY1 via the transforming growth factor-β1-Smad2/3 pathway, Frontiers in Immunology, 2018, 9: 1754.
Gan Lingling#; Zhang Xuemei#; Xu Xiuyu; Xu Wenchun; Lu Chang; Cui Jin; Wang Hong*; spd1672, a novel in vivo-induced gene, affects inflammatory response in a murine model of Streptococcus pneumoniae infection, Canidian Journal of Microbiology, 2018, 64: 401-408.
Sun Kunling; Xu Xiuyu; Yan Jinrong, Zhang Liping*. Evaluation of six phenotypic methods for the detection of carbapenemases in gram-negative bacteria with characterized resistance mechanisms, Annals of Laboratory Medicine, 2017, 37: 305-312.
Xu Xiuyu; Wang Hong; Liu Yusi; Wang Yiping; Zeng Lingbing; Wu Kaifeng; Wang Jianmin; Ma Feng; Xu Wenchun; Yin Yibing; Zhang Xuemei*; Mucosal immunization with the live attenuated vaccine SPY1 induces humoral and Th2-Th17-regulatory T cell cellular immunity and protects against pneumococcal infection, Infection and Immunity, 2015, 83: 90-100.
ZhangChuanming, XuXiuyu, PuShuli, HuangShifeng, SunJide, YangShuangshuang, ZhangLiping*. Characterization of carbapenemases, extended spectrum β-lactamases, quinolone resistance and aminoglycoside resistance determinants in carbapenem-non-susceptible Escherichia coli from a teaching hospital in Chongqing, Southwest China. Infection, Genetics and Evolution, 2014, 27: 271-276.
Xu Xiuyu, Meng Jiangping, Wang Yiping, Zheng Jie, Wu Kaifeng, ZhangXuemei, Yin Yibing, ZhangQun*. Serotype-independent protection against pneumococcal infections elicited by intranasal immunization with ethanol-killed pneumococcal strain, SPY1.Journal ofMicrobiology, 2014, 52(4): 315-323.






研究方向
常见院内感染病原体致病机制研究，常见院内耐药菌的耐药机制及耐药表型检测新方法研究