秦文灵 Title：副教授/博导
E-mail Address：wenling.qin@cqu.edu.cn
Tel.：**


个人/团队介绍
学习工作经历 2016.7-至今, 重庆大学, 药学院, 讲师，副教授
2014.10-2016.5, Allecra Therapeutics, 研发部, 研发顾问(中国)
2014.5-2014.9, 意大利国家科学研究院有机合成与光化学研究中心（CNR-ISOF）, 研究助理
2010.11–2014.4, 博士， 意大利博洛尼亚大学化学学院, 导师: Panunzio Mauro
2007.9 –2010.6, 硕士， 重庆大学化学化工学院, 导师: 夏之宁，肖尚友
2003.9 –2007.7, 学士， 兰州大学药学院, 导师: 赵全义


研究领域 不对称合成（有机小分子催化）
药物化学（β-内酰胺类抗生素新药发现及工艺研究）
项目成果 重庆市重点产业共性关键技术创新专项重点研发项目（200万）
国家自然科学基金青年项目（22.5万）
重庆大学科研启动基金（20万）
法国Allecra Therapeutic公司科技合作项目（40万）
中国人民解放军陆军特色医学中心科技合作项目（30万元）
代表性文章 1."Chiral Naphthyl-C2-Indole as Scaffold for Phosphine Organocatalysis: Application in Asymmetric Formal [4 + 2] Cycloaddition Reactions" Tingting He, Lei Peng, Shan Li, Fangli Hu, Chuandong Xie, Shengli Huang, Shiqi Jia, Wenling Qin*, Hailong Yan* Org. Lett. 2020, 22, 17, 6966-6971.
2."N-Iodosuccinimide-Mediated Dimerization of 2-Alkynylnaphthols: A Highly Diastereoselective Construction of Bridged Polycyclic Compounds via Vinylidene ortho-Quinone Methide Intermediate" Yu Tan, Zhengxing Zhao, Zhili Chen, Shengli Huang, Shiqi Jia, Lei Peng, Da Xu, Wenling Qin*, Hailong Yan*. Org. Lett. 2020, 2020, 22, 11, 4461–4466.
3."Antibacterial Agents Targeting the Bacterial Cell Wall" Shan Li, Wenling Qin *, Mauro Panunzio, Stefano Biondi * Curr. Med. Chem. 2020, 27, 1-24.
4."Organocatalytic Enantioselective γ-Elimination: Applications in the Preparation of Chiral Peroxides and Epoxides" Fangli Hu, Zhili Chen, Yu Tan, Da Xu, Shengli Huang, Shiqi Jia, Xiangnan Gong, Wenling Qin* Hailong Yan* Org. Lett. 2020, 22, 5, 1934-1940.
5."Organocatalytic Enantioselective Selenosulfonylation of a C-C Double Bond to Form Two Stereogenic Centers in an Aqueou Medium" Zhili. Chen, Fangli. Hu, Shengli. Huang, Zhengxing. Zhao, Hui. Mao* and Wenling. Qin* J. Org. Chem. 2019, 84, 8100?8111.
6."Metal-free difunctionalization of alkynes to access tetrasubstituted ole?ns through spontaneous selenosulfonylation of vinylidene ortho-quinone methide (VQM)" Shengli. Huang, Zhili. Chen, Hui. Mao, Fangli. Hu, Dongmei. Li, Yu Tan, Fengqing. Yang, Wenling. Qin* Org. Biomol. Chem. 2019, 17, 1121–1129.
7."Direct Preparation of Indole Hemiaminals through Organocatalytic Nucleophilic Addition of Indole to Aldehydes" Nan. Zhang, Yige. Li, Zhili. Chen, Wenling. Qin* Synthesis 2018, 50, 4063-4070.
8."K₂S₂O₈ Activated Friedel-Crafts Type Alkylation of Indoles with α-Amido Sulfones" Xiaoyan. Wu, Lu. Xue, Shilong. Luo, Shiqi. Jia, Jun. Ao, Wenling. Qin* Synthesis, 2017, 49, 5017-5024.
9."α-Alkyl-α-aryl (Trimethyltin) Nitriles: Versatile Nucleophilic Intermediates in Aldol-Like Reactions" Wenling Qin, Sha Long, Alessandro Bongini, and Mauro Panunzio Eur. J. Org. Chem. 2015, 3495-3505.
10."β-Lactam Antibiotics Renaissance" Wenling Qin; Sha Long, Mauro Panunzio, Stefano Biondi Antibiotics, 2014, 3 (2):193-215.
11.“一种制备含腈基γ-醇化合物的方法”（发明专利， 第一发明人，CNA），已授权。