个人简介

-学习经历
2007/09-2013/06，西南大学，家蚕基因组生物学国家重点实验室，博士
2003/09- 2007/06，西南大学，生物技术学院，学士

-工作经历
2019年9月-2020年8月，筑波大学，访问****
2016年1月-至今，重庆大学，副研究员
2015年6月-2015年12月，重庆大学，讲师
2013年9月-2015年5月，重庆大学，博士后




研究方向
研究方向：昆虫发育遗传学

研究内容：在动物发育过程中，甾醇类激素常以“脉冲”方式进行分泌从而达到精确调控发育和生殖等多个生理进程的目的。昆虫最重要的甾醇类激素-蜕皮激素同样也是如此。如果蜕皮激素脉冲的起始以及持续时间发生改变，通常会引起幼虫蜕皮和变态发育的异常。在昆虫中，蜕皮激素的合成和代谢过程何时开始及结束是调控激素脉冲的最主要因素。目前，课题组主要以家蚕和黑腹果蝇为模式，通过基因组，转录组，分子生物学，细胞生物学以及遗传学等研究方法和手段，揭示昆虫蜕皮激素脉冲形成的分子机理，及其对蜕皮和变态发育进程的调控机制。

主讲课程
发育生物学

学术兼职
中国昆虫学会基因组专委会委员

主要成果
- First author & Corresponding author
1. Duan HT, Yang X, Bu ZY, Li XY, Zhang Z and Sun W* (2020). Identification and characterization of genes involved in ecdysteroid esterification pathway contributing to the high 20-hydroxyecdysone resistance of Helicoverpa armigera. Frontiers in Physiology. 11
2. Wang CF, Zhang Z*, Sun W* (2018). Ecdysone oxidase and 3-dehydroecdysone-3β-reductase contribute to the synthesis of ecdysone during early embryonic development of the silkworm. International Journal of Biological Sciences. 14:1472-1482
3. Sun W*, Wang CF, Zhang Z (2017). Transcription factor E74A affects the ecdysone titer by regulating the expression of the EO gene in the silkworm, Bomby mori. BBA-General Subjects. 1861:551–558
4. Sun W, Shen YH, Zhou LX, Zhang Z* (2016). Ecdysone titer determined by 3DE-3beta-reductase enhances the immune response in the silkworm. Journal of Immunology 196:1646-1654
5. Sun W, Zhao XW and Zhang Z*. (2015) Identification and evolution of the orphan genes in the domestic silkworm, Bombyx mori. FEBS Letters 589: 2731–2738
6. Sun W, Shen YH, Han MJ, Cao YF and Zhang Z*. (2014) An adaptive transposable element insertion in the regulatory region of the EO gene in the domesticated silkworm, Bombyx mori. Molecular Biology and Evolution 31:3302-3313
7. Sun W, Shen YH, Qi DW, Xiang ZH and Zhang Z*. (2012) Molecular cloning and characterization of ecdysone oxidase and 3-dehydroecdysone-3α-reductase involved in the ecdysone inactivation pathway of silkworm, Bombyx mori. International Journal of Biological Sciences 8:125-138
8. Sun W, Shen YH, Yang WJ, Cao YF, Xiang ZH and Zhang Z*. (2012) Expansion of the silkworm GMC oxidoreductase genes is associated with immunity. Insect Biochemistry and Molecular Biology 42:935-945
9. Sun W, Yu HS, Shen YH, Banno Y, Xiang ZH and Zhang Z*. (2012) Phylogeny and evolutionary history of the silkworm. Science China Life Sciences 55:483-496
- Coauthor
1. Kamiyama T, Sun W, Tani N, Nakamura A and Niwa R. (2020) Poly(A) binding protein is required for nuclear localization of the ecdysteroidogenic transcription factor molting defective in the prothoracic gland of Drosophila melanogaster. Frontiers in Genetics. 11:636
2. Dai ZJ, Sun W and Zhang Z*. (2018) Comparative analysis of iTRAQ-based proteomes for cocoons between the domestic silkworm (Bombyx mori) and wild silkworm (Bombyx mandarina). Journal of Proteomics 192: 366-373
3. Zhang Q, Sun W, Sun BY, Xiao Y and Zhang Z*. (2017) The dynamic landscape of gene regulation during Bombyx mori oogenesis. BMC Genomics 18:714
4. Yu XB, Shen YH, Cui QM, Chen Y, Sun W, Huang XZ* and Zhu Y. (2017) Silkworm (Bombyx mori) has the capability to accumulate C20 and C22 polyunsaturated fatty acids. European Journal of Lipid Science and Technology. 120: **
5. Fu P, Sun W, Zhang Z*. (2016) Molecular cloning, expression and characterization of acylpeptide hydrolase in the silkworm, Bombyx mori. Gene 580:8-16
6. Zhao Q, Han MJ, Sun W and Zhang Z*. (2014) Copy number variations among silkworms. BMC Genomics 15:251
7. Guo Y, Shen YH, Sun W, Kishino H, Xiang ZH and Zhang Z*. (2011). Nucleotide diversity and selection signature in the domesticated silkworm, Bombyx mori, and wild silkworm, Bombyx mandarina. Journal of Insect Science 11:155

联系方式
邮箱：sunwei077@cqu.edu.cn