教师姓名：胡宗利
邮箱地址：huzongli@cqu.edu.cn
工作电话：未公开
?胡宗利??博士，教授，硕士生导师，博士生导师。

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主要从事果实成熟分子调控机理研究，蛋白的表达与纯化等方面的研究工作，主要负责本科专业基础课程《普通遗传学》和《分子生物学》的理论教学工作。先后主持国家自然科学基金、重庆市自然科学基金、教育部“春晖”计划、中央高校基本业务费等项目5项，并主研国家高技术研究发展计划（863计划）项目、国家自然科学基金、重庆市自然科学重点基金、重庆市科技攻关项目等10余项，发表文章80余篇，其中国外SCI收录论文30余篇，国家发明专利授权12项，另发明专利申请7项。2010年获得重庆大学首届“黄尚廉院士青年创新奖”之青年教师创新奖。2011年获得重庆大学先进工作者称号。

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主要研究方向：

1、果实成熟分子调控机理研究；

2、植物功能基因的研究；

3、新型转基因植物的培育；

4、利用微生物表达体系进行功能蛋白的表达与纯化；

5、植物的抗病性、抗逆性研究。

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?近年来发表SCI文章目录：

Hu?Z,?Deng?L,Yan?B,?Pan?Y,?Luo?M,?Chen?X,?Hu?T,?Chen?G.?Silencing?LeSGR1?gene?in?tomato?inhibits?chlorophyll?degradation?and?exhibits?a?stay-green?phenotype.?Biologia?Plantarum,?2011,55?(1):?27-34.?(SCI?)

Hu?Z,?Deng?L,.?Chen?X,?Wang?P?and?Chen?G.?Co-suppression?of?the?EIN2-homology?Gene?LeEIN2?inhibits?fruit?ripening?and?reduces?ethylene?sensitivity?in?tomato.?Russian?Journal?of?Plant?Physiology.?2010,?57(4):?554-559.?(SCI?)

Hu?Z,?Zhao?Z,?Pan?Y,?Tu?Y,?Chen?G.?A?Powerful?Hybrid?puc?Operon?Promoter?Tightly?Regulated?by?Both?IPTG?and?Low?Oxygen?Level.?Biochemistry?(Moscow),?2010,75(4):?519-525.?(SCI?)

Hu?Z,?Zhang?N,?Gu?F,?Li?Y,?Deng?X,?Chen?G.?Expression,?purification?and?characterization?of?recombinant?targeting?bifunctional?hirudin?in?Pichia?pastoris.?African?Journal?of?Biotechnology.?2009,8(20):?5571-5577.?(SCI?)

Hu?Z,?Zhao?Z,?Liang?Y,?Li?Y,?Chen?G.?A?novel?recombinant?fusion?protein?exhibited?inhibitory?activities?on?platelet?aggregation?and?thrombin.?Letters?in?Drug?Design?&?Discovery,?2010,7(3):182-187.?(SCI?)

Zhao?Z,?Hu?Z?（共同第一作者）,?Nie?X,?Cheng?L,?Ding?G,?Luo?M,?Pan?Y,?Liang?Y，Chen?G.?A?novel?rhodobacter?sphaeroides?expression?system?for?real-time?evaluation?of?heterologous?protein?expression?levels.?Protein?&?Peptide?Letters,?2011,18(6):568-572.?(SCI?)

Pan?Y,?Chen?G,?Lu?C,?Chen?X,?Hu?Z?(通讯作者).?Functional?Analysis?of?Tomato?LeEIL1?in?an?Arabidopsisein2?mutant.?Acta?Physiologiae?Plantarum.?2011,33(2):?489-496?.?(SCI?)

Gao?J,?Hu?Z?(通讯作者),?Chen?G,?Zhao?Z,?Pan?Y，Ren?Y.?A?novel?targeting?multi-functional?fusion?protein?possessed?inhibitory?activities?on?bacterium,?thrombin?and?platelet?aggregation.?Protein?Journal.?2011,30:521-528.?(SCI)?

Chen?X,?Hu?Z?（共同第一作者）,?Yang?Y,?Pan?Y,?Zhao?Z,?Chen?G.?High?Level?Expression?of?Human?Chemokine?Receptor?CCR-5?in?Fission?Yeast.?African?Journal?of?Biotechnology.?2011,10：17010-17015.?(SCI)

Deng,?L?,?Pan,?Y?,?Chen,?X?,?Chen,?G?,Hu?Z(通讯作者).?Small?RNAs?were?involved?in?homozygous?state-associated?silencing?of?a?marker?gene?(Neomycin?phosphotransferase?II:?nptII)?in?transgenic?tomato?plants.?Plant?Physiology?and?Biochemistry,?2013,?68:?8-15.(SCI)??

Nie?X,?Zhao?Z,?Chen?G,??Zhang?B,?Ye?M,?Hu?Z?(通讯作者).?Brassica?napus?possesses?enhanced?antioxidant?capacity?via?heterologous?expression?of?anthocyanin?pathway?gene?transcription?factors.?Russian?Journal?of?Plant?Physiology,?2013,?60（1）:108-115.?(SCI)

Zhu?M,?Chen?G?,?Zhou?S,?Tu?Y,?Wang?Y,?Dong?T?,?HuZ?(通讯作者).?A?new?tomato?NAC?(NAM/ATAF1/2/CUC2)?transcription?factor,?SlNAC4,?plays?an?important?role?in?fruit?ripening?and?carotenoid?accumulation.?Plant?＆cell?physiology.Accepted.(SCI)

Dong?T,?Hu?Z,?Deng?L,?Wang?Y,?Zhu?M,?Zhang?J,?Chen?G.?A?tomato?MADS-Box?rranscription?factor,?SlMADS1,?acts?as?a?negative?regulator?of?fruit?ripening.?Plant?Physiology,?2013,163:?1026–1036.?(SCI)??

Hu?T,?Zeng?H,?Hu?Z,?Qv?X,?Chen?G.?Overexpression?of?the?Tomato?13-Lipoxygenase?Gene?TomloxD?Increases?Generation?of?Endogenous?Jasmonic?Acid?and?Resistance?to?Cladosporium?fulvum?and?High?Temperature.Plant?Molecular?Biology?Reporter,?2013,?31,?(5):?1141-1149.(SCI)

Hu?T,?YangY,?Zeng?H,?Hu?Z,?Chen?Z,?Chen?G,?Wu?Y.?Transgenic?pepper?plants?carrying?RNA?interference?constructs?of?CaCOI1?gene?show?severe?abnormality.?Mol?Breeding,?2013,31:971–979.?(SCI)

He?S,?Tan?L,Hu?Z,Chen?G,Wang?G,?HuT.?Molecular?characterization?and?functional?analysis?by?heterologous?expression?in?E.?coli?under?diverse?abiotic?stresses?for?OsLEA5,?the?atypical?hydrophobic?LEA?protein?from?Oryza?sativa?L.?Molecular?Genetics?and?Genomics.?2012,?287(1):?39-54.??(SCI)

Zhou?S,?Hu?Z,?Zhu?M,?Zhang?B,?Deng?L,?Pan?Y,?Chen?G.?Biochemical?and?molecular?analysis?of?a?temperature-sensitive?albino?mutant?in?kale?named?‘‘White?Dove’’.?Plant?Growth?Regulation.?Accepted.?(SCI)

Zhang?B,?HuZ,?Zhang?Y,?Li?Y,?Zhou?S,?Chen?G.?A?putative?function?of?a?MYB?transcription?factor?induced?by?low?temperature?regulates?anthocyanin?biosynthesis?in?purple?kale?(Brassica?Oleracea?var.?acephala?f.?tricolor).?Plant?Cell?Reports.?2012,31:281-289.?(SCI)

Pan?Y,?Seymour?BG,?Lu?C,?Hu?Z,?Chen?X,?Chen?G.An?Ethylene-response?Factor?(ERF5)?Promoting?Adaptation?to?Drought?and?Salt?Tolerance?in?Tomato.?Plant?Cell?Reports.?2012,31:349-360.?(SCI)

Hu?T,?Qv?X,?Hu?Z,?Chen?G,?Chen?Z..?Expression,?Molecular?characterization?and?detection?of?lipoxygenase?activity?of?TomloxD?from?tomato?African?Journal?of?Biotechnology.?2011,10(4):?491-498.?(SCI)

Zhao?Z,?Hu?Z,?Liang?Y,?Hu?T,?Tu?Y,?Chen?G.?One-Step?Purification?of?Functional?Light-harvesting?2?Complex?from?Rhodobacter?sphaeroides.?Protein?and?peptide?letters,?2010,17(4):?444-448.?(SCI)

Wang?Y,?Hu?Z,?Yang?Y,?Chen?X,?Chen?G.?Function?annotation?of?an?SBP-box?gene?in?Arabidopsis?based?on?analysis?of?co-expression?networks?and?promoters.?International?journal?of?molecular?sciences,?2009,10(1):?116-132.?(SCI)

Wang?Y,?Hu?Z,?Yang?Y,?Chen?X,?Chen?G.?Genome-wide?Identification,?Phylogeny?and?Expression?Analysis?of?SBP-box?Gene?Family?in?Grape.?Russian?Journal?of?Plant?Physiology.?2010,57(2):?273-282.?(SCI)

Hu?G,?Hu?Z,?Li?Y,?Gu?F,?Zhao?Z,?and?Chen?G.?A?Splicing?Site?Mutation?in?BrpFLC1?and?Repressed?Expression?of?BrpFLC?Genes?Are?Associated?with?the?Early?Flowering?of?Purple?Flowering?Stalk.?Russian?Journal?of?Plant?Physiology,?2011,58(3):431–438.?(SCI)

Wang?W,?Hu?Z,?Li?J,?Chen?G.?Expression?characterization?and?actual?function?of?the?second?pucBA?in?Rhodobacter?sphaeroides.?Bioscience?reports,?2009,29(3):165-172.?(SCI)

Wang?W,?Hu?Z,?Chen?X,?Zhao?Z,?Li?J,?Chen?G.?Heterologous?synthesis?and?assembly?of?functional?LHII?antenna?complexes?from?Rhodovulum?sulfidophilum?in?Rhodobacter?sphaeroides?mutant.?Molecular?biology?reports,?2009,36(7):?1695-1702.?(SCI)

Yang?Y,?Hu?Z,?Liu?Z,?Wang?Y,?Chen?X,?Chen?G.?High?human?GLUT1,?GLUT2?and?GLUT3?expression?in?Schizosaccharomyces?pombe.?Biochemistry?(Moscow),?2009,74?(1):?95-102.?(SCI)

Wang?W,?Hu?Z,?Li?J,?Chen?X,?Chen?G.?Characteristics?of?light-harvesting?complex?II?mutant?of?Rhodobacter?sphaeroides?with?alterations?at?the?transmembrane?helices?of?beta-subunit.?Biochemistry?(Moscow),?2009,74(7):807-812.?(SCI)

Chen?G,?Hu?Z,?Grierson?D.?Differential?regulation?of?tomato?ethylene?responsive?factor?LeERF3b,?a?putative?repressor,?and?the?activator?Pti4?in?ripening?mutants?and?in?response?to?environmental?stresses.?Journal?of?plant?physiology,?2008,165?(6):?662-670.?(SCI)

Ren?Y,?Chen?G,?Hu?Z,?Chen?X,?Yan?B.?Applying?Novel?Three?Dimensional?Holographic?Vector?of?Atomic?Interaction?Field?to?QSAR?Studies?on?Artemisinin?Derivatives.?QSAR?&?Combinatorial?Science,?2008,?27(2):?198-207.?(SCI)

Wang?Y,?Chen?G,?Yang?Y,?Hu?Z,?Chen?X.?A?systems?biology?analysis?of?protein-protein?interactions?in?the?APOBEC?family.?Life?Sciences,?2008,83:521-530.?(SCI)

Wang?J,?Chen?G,?Hu?Z,?Chen?X.?Cloning?and?characterization?of?the?EIN2-homology?gene?LeEIN2?from?tomato.?DNA?Sequence,?2007,?18(1):?33-38.?(SCI)?

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近年来已授权专利目录：

（1）胡宗利，陈国平，高建阁，张陈明，吴祥华，邓磊。利用基因工程技术获得高抗病毒马铃薯植株的方法。专利号：ZL?**2.5；授权年份：2011；中国授权。

（2）胡宗利，刘志昭，陈国平，邓磊，潘宇，胡廷章，涂昀。蜂毒肽基因裂殖酵母工程菌及其构建方法和应用。专利号：ZL?**1；授权年份：2011；中国授权。

（3）胡宗利，任彦荣，陈国平。水溶性青蒿素衍生物及其制备方法。专利号：ZL**8；授权年份：2010；中国授权。

（4）胡宗利，陈绪清，陈国平，赵志平，潘宇，胡廷章。一种同时受外源IPTG和O₂浓度调控的表达载体及其构建方法。专利号：ZL?**8.7；授权年份：2011；中国授权。

（5）胡宗利，陈绪清，陈国平，潘宇，杨妤欣，胡廷章。一种异源表达和纯化人艾滋病病毒辅助受体CCR5的方法。专利号：ZL?**2.X；授权年份：2011；中国授权。

（6）陈国平，胡宗利，邓晓洁，刘志昭，顾峰。一种具有趋化作用的人类RANTES蛋白的异源表达和纯化方法。专利：ZL?**2.3；授权年份：2011；中国授权。

（7）陈国平，梁岩，胡宗利，李勇，胡功铃，王达菲，王炳琴。靶向性抗血栓形成的融合蛋白及其制备方法和应用。专利号：ZL?**7.3；授权年份：2011；中国授权。

（8）陈国平，任彦荣，胡宗利。半乳糖-青蒿素及其制备方法。专利号：ZL?**1.9；授权年份：2011；中国授权。

（9）胡宗利，陈国平，潘宇，赖文泉，任彦荣，陈绪清，王美胜。一种保持高青蒿素含量的青蒿无性繁殖方法。专利号：ZL?**8.8；授权年份：2012；中国授权。

（10）胡宗利，高建阁，陈国平，涂昀，赵志平，潘宇。靶向多功能防栓融合蛋白及其制备方法和应用。专利号：ZL?**4；授权年份：2012；中国授权。

（11）胡廷章，曾华，陈国平，胡宗利，王贵学，杨勇卫，谭丽莉。辣椒CaCOI1.2基因及其重组表达载体和应用。专利号：ZL?**6.1；授权年份：2013；中国授权。

（12）夏玉先，胡宗利，王中康，彭国雄；一种提高金龟子绿僵菌孢子耐贮和耐热性的方法。专利证书号：378208；授权年份：2008；中国授权。

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研究生学习期间可能掌握的主要技术：

分子克隆技术、分子表达技术、核酸分离纯化技术、定量PCR技术、凝胶电泳技术、免疫印迹与免疫沉淀技术、微生物培养技术、植物组织培养技术、动物细胞培养技术、植物转基因技术、微生物转化技术、酶联免疫吸附测定技术、蛋白质分离纯化技术等等。

欢迎热爱科学，具有生物学、化学、医学等相关知识背景，良好英语能力和较强的实验动手技能的本科生报考硕士研究生。Email:?huzongli@cqu.edu.cn

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