980nm脉冲激光诱发听神经冲动

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清华大学辅仁网/2017-07-07

980 nm脉冲激光诱发听神经冲动

关添¹, 吴默村^1,2, 朱凯^1,2, 王健³

1. 清华大学深圳研究生院, 生物医学工程研究中心, 深圳 518055;
2. 清华大学生物医学工程系, 北京 100084;
3. 深圳信息职业技术学院电子与通信学院, 深圳 518172

980 nm pulsed laser-induced auditory nerve impulses

GUAN Tian¹, WU Mocun^1,2, ZHU Kai^1,2, WANG Jian³

1. Research Center of Biomedical Engineering, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China;
2. Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China;
3. Electronics and Communication College, Shenzhen Institute of Information Technology, Shenzhen 518172, China

摘要:

输出: BibTeX | EndNote (RIS)

摘要为了最优化选取刺激人工耳蜗激光参数,该文选用波段980 nm脉冲激光刺激豚鼠听神经,成功诱发了光刺激复合动作电位(optical compound action potentials, oCAPs); 通过分析实验结果表明: 光刺激具有一定的安全性,其刺激强度不是越大越好,存在一个最佳区域范围。

关键词 ：人工耳蜗,近红外激光,光刺激,光质复合动作电位(oCAPs)

Abstract：A 980 nm near infrared laser was used to stimulate the auditory nerve in guinea pig cochlea to provide useful optical parameters for the development of an optical cochlear implant. The 980 nm pulsed laser can evoke optical compound action potentials (oCAPs) from guinea pig cochlea. The experimental results also demonstrate the security of optical stimulus and larger optical intensities not always giving better results.

Key words：cochlear implant near infrared laser optical stimulation optical compound action potentials (oCAPs)

收稿日期: 2015-01-07 出版日期: 2015-09-08

ZTFLH:

R318.6

引用本文:

关添, 吴默村, 朱凯, 王健. 980 nm脉冲激光诱发听神经冲动[J]. 清华大学学报（自然科学版）, 2015, 55(6): 700-704.
GUAN Tian, WU Mocun, ZHU Kai, WANG Jian. 980 nm pulsed laser-induced auditory nerve impulses. Journal of Tsinghua University(Science and Technology), 2015, 55(6): 700-704.

链接本文:

http://jst.tsinghuajournals.com/CN/或 http://jst.tsinghuajournals.com/CN/Y2015/V55/I6/700

图表:

图1　光学平台示意图

图2　豚鼠耳蜗示意图

图3　声刺激CAP和光刺激oCAPs比较

图4　光刺激强度与oCAPs幅值的关系

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