文献详情
Combining ultrasonic and computed tomography scanning to characterize mechanical properties of cancellous bone in necrotic human femoral heads
文献类型：期刊
通讯作者：Chen, DD (reprint author), Beijing Inst Technol, Sch Life Sci, Beijing 100081, Peoples R China.
期刊名称：MEDICAL ENGINEERING & PHYSICS影响因子和分区
年：2019
卷：66
页码：12-17
ISSN：1350-4533
关键词：Femoral head necrosis; Ultrasonic scanning; Computed tomography; Elastic modulus; Mechanical properties
摘要：Image-based finite element modelling has been commonly used to determine the biomechanical behaviours of human femora, particularly for the diagnosis of femoral head necrosis. One of the fundamental aspects of biomechanical modelling is the relationship between bone density, which is obtained from images, and elastic modulus. While there exist some empirical equations relating density with elastic modulus, the characterization of this relationship remains incomplete, especially for necrotic femo ...More
Image-based finite element modelling has been commonly used to determine the biomechanical behaviours of human femora, particularly for the diagnosis of femoral head necrosis. One of the fundamental aspects of biomechanical modelling is the relationship between bone density, which is obtained from images, and elastic modulus. While there exist some empirical equations relating density with elastic modulus, the characterization of this relationship remains incomplete, especially for necrotic femoral heads. The objective of this study was to determine the relationship between density and elastic modulus by combining ultrasonic scanning and computed tomography (CT). Bone specimens were surgically removed from the femora of eight persons (seven females and one male in the age range of 55-68 years old) and underwent both ultrasonic and CT scanning. The images were processed with MATLAB scripts, and a bilinear interpolation algorithm was used to determine the relationship between the CT-measured densities and ultrasound-measured elastic moduli. The results showed different density-elastic modulus relations between the hardening strap of the necrotic region and non-hardening strap areas of the necrotic region. The uniqueness of this study is the characterization of mechanical properties (in the present study, the density-modulus relationship) from clinical images, which would be valuable in computational biomechanics used for the diagnosis and treatment evaluation of femoral head necrosis. (C) 2019 Published by Elsevier Ltd on behalf of IPEM. ...Hide

DOI：10.1016/j.medengphy.2019.02.002
百度学术：Combining ultrasonic and computed tomography scanning to characterize mechanical properties of cancellous bone in necrotic human femoral heads
语言：外文
人气指数：1
浏览次数：1
基金：National Key R&D Program of China [2017YFC0107901]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China [81770465, 11702008]; Support Plan for High-level Faculties in Beijing Municipal Universities [CITTCD201804011]; Beijing Excellent Talents Funds [2017000020124G277]
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