何秋霞,
韩利文,
陈锡强,
刘可春,
山东省科学院生物研究所, 山东省生物检测技术工程实验室, 山东省生物传感器重点实验室, 山东省科学院药物筛选技术重点实验室, 济南 250014
作者简介: 韩建(1983-),男,博士,助理研究员,研究方向为环境/生态毒理学和药物筛选,E-mail:hanjian251314@163.com.
通讯作者: 刘可春,hliukch@sdas.org
基金项目: 山东省科学院青年基金项目(2015QN012)；山东省自主创新及成果转化专项(2014ZZCX02105)；山东省自然科学基金三院联合基金项目(ZR2015YL013)中图分类号: X171.5
Review on Toxicology of Chemical Pollutants on Fish Swimbladder
Han Jian,He Qiuxia,
Han Liwen,
Chen Xiqiang,
Liu Kechun,
Biology Institute of Shandong Academy of Sciences, Shandong Provincial Engineering Laboratory for Biological Testing Technology, Key Laboaratory for Biosensor of Shandong Province, Key Laboratory for Drug Screening Technology of Shandong Academy of Sciences, Jinan 250014, China
Corresponding author: Liu Kechun,hliukch@sdas.org
CLC number: X171.5
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摘要:鱼鳔(swimbladder)是帮助有鳔鱼类完成呼吸、保持流体静力、感觉声音等生理活动的重要功能器官之一。化学污染物暴露能够影响鱼鳔的正常发育或充气,对有鳔鱼类的生存具有潜在威胁。本文首先对鱼鳔功能、形态发育及分子机制进行了介绍。其次对化学污染物导致的鱼鳔发育异常或不充气等毒性效应进行了总结,对特定污染物的潜在作用机制进行了综述。最后对鱼鳔的环境/生态毒理学研究提出展望。
关键词: 污染物/
鳔/
毒性评价
Abstract:Swimbladder is one of the most essential organs for the fish with such a gas chamber, and plays a key role in performing respiration, keeping hydrostatics and sensing sound, etc. Exposure to chemical contaminants could affect development and inflation of fish swimbladder, and thus might lead to a potential threat to fish with swimbladder. In this review, firstly, the function, morphological development and molecular mechanisms of fish swimbladder were introduced. Secondly, the reports on abnormal development of swimbladder and its non-inflation caused by exposure to chemical pollutants were summarized, and the potential mechanisms of action were reviewed. Finally, the perspectives on environmental toxicology or ecotoxicology of fish swimbladder were proposed.
Key words:contaminants/
swimbladder/
toxicity evaluation.
