张建军

健康与遗传心理学研究室副研究员

电 话:86-

传 真:86-

通讯地址:北京市朝阳区林萃路16号院中科院心理所

邮政编码:100101

电子邮件:zhangjj@psych.ac.cn

课题组网站:

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简历：
2016.12-2017.6 美国国立卫生研究院（NIH） 访问****
2012.7-　　　 中国科学院心理研究所，助理研究员
2007.9-2012.7 北京大学生命科学学院，生理学专业，博士
2003.9-2007.7 兰州大学生命科学学院，生物学基地班，学士

研究领域：
以大鼠为主要动物模型，通过化学遗传学、光遗传学、膜片钳、内窥成像、分子生物学、生物化学及药理学等技术手段，研究药物成瘾及情绪记忆的脑机制，特别是表观遗传与神经环路调控机制。
具体方向:
1.药物成瘾的表观遗传学调控机制
2.情绪记忆的神经环路调控机制

社会任职：
中国毒理学会药物依赖性毒理学专业委员会青年委员（2018.12.01-2023.11.30）
中国药物滥用防治协会青年专家委员会委员（2017.05.10-2022.05.09）

获奖及荣誉：

代表论著：
1. Zhang J.J.#, Jiang F.Z.#, Zheng W., Duan Y., Jin S.B., Shen F., Liang J., Li M., Sui N., DNMT3a in the hippocampal CA1 is crucial in the acquisition of morphine self-administration in rats. Addict Biol., 2019(#co-first author)
2. Zhang, J. J. * & Kong, Q, Locomotor activity: A distinctive index in morphine self-administration in rats. Plos One, 2017, 12 (4):e**.
3. Zhang, J. J., Liu, X. D., & Yu, L. C. *, Influences of morphine on the spontaneous and evoked excitatory postsynaptic currents in lateral amygdala of rats. Physiol Res., 2016, 65 (1), 165–169.
4. Zhang, J. J., Han, J., & Sui, N, Okadaic acid blocks the effects of 5-aza-2-deoxycytidine on consolidation, acquisition and retrieval of morphine-induced place preference in rats. Neuropharmacology, 2014, 86, 282-293.
5. Zhang, J. J., Ma, X., & Yu, L. C, Repeated paired-testing impairs extinction of morphine-induced conditioned place preference dependent on the inter-test interval in rats. Neurosci Lett, 2012, 516(1), 72-74.
6. Ma, X. #, Zhang, J. J. #, & Yu, L. C, Post-retrieval extinction training enhances or hinders the extinction of morphine-induced conditioned place preference in rats dependent on the retrieval-extinction interval. Psychopharmacology (Berl), 2012, 221(1), 19-26. (#co-first author)
7. Liu, P.#, Zhang, J. J.#, Li, M., & Sui, N.*, Distinctive Roles of 5-Aza-2′-deoxycytidine in Anterior Agranular Insular and Basolateral Amygdala in Reconsolidation of Aversive Memory Associated with Morphine in Rats. Front Behav Neurosci, 2016, 15;10:50. (#co-first author)
8. Lin, X. J.#, Zhang, J. J.#, & Yu, L. C. *, GluR2-3Y Inhibits the Acquisition and Reinstatement of Morphine-Induced Conditioned Place-Preference in Rats. Neurosci. Bull., 2016, 32 (2), 177–182. (#co-first author)
9. Jiang, X. #, Zhang, J. J. #, Wang, M. Y., & Sui, N, Differential muscarinic modulation of synaptic transmission in dorsal and ventral regions of the rat nucleus accumbens core. Physiol Res, 2014, 63(1), 135-142. (# equal contribution)
10. Li, Xuan.,Carreria, Maria B..,Witonsky, Kailyn R..,Zeric, Tamara.,Lofaro, Olivia M.., Zhang, J. J., ...&Shaham, Yavin. Role of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving. Biological psychiatry, 2018, (17),32314-4.
11. Li, Xuan.,Witonsky, Kailyn R..,Lofaro, Olivia M..,Surjono, Felicia.,Zhang, Jianjun.,...&Shaham, Yavin. Role of Anterior Intralaminar Nuclei of Thalamus Projections to Dorsomedial Striatum in Incubation of Methamphetamine Craving. JOURNAL OF NEUROSCIENCE, 2018, 38(9),2270-2282.
12. Wang, Xingyue.,Qiao, Yanhua.,Dai, Zhonghua.,Sui, Nan.,Shen, Fang., Zhang, Jianjun., &Liang, Jing.(2019).Medium spiny neurons of the anterior dorsomedial striatum mediate reversal learning in a cell-type-dependent manner. BRAIN STRUCTURE & FUNCTION,224(1),419-434.
13. Liu, Z., Zhang, J. J., Liu, X. D., & Yu, L. C, Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats. Neurosci Lett, 2012, 518(2), 167-171.
14. Liu, X. D., Zhang, J. J., Wang, Y., & Yu, L. C, Inhibitory effects of calcitonin gene-related peptide on long-term potentiation induced in hippocampal slices of rats. Neurosci Lett, 2011, 494(1), 10-13.
15. Li, J., Zhang, J. J., Xu, S. L., & Yu, L. C, Antinociceptive effects induced by injection of the galanin receptor 1 agonist M617 into central nucleus of amygdala in rats. Neurosci Lett, 2012, 526(1), 45-48.
16. Liu, Z., Liu, X. D., Zhang, J. J., & Yu, L. C, Increases in alphaCaMKII phosphorylated on Thr286 in the nucleus accumbens shell but not the core during priming-induced reinstatement of morphine-seeking in rats. Neurosci Lett, 2012, 526(1), 39-44.
17. Xu, S. L., Li, J., Zhang, J. J., & Yu, L. C, Antinociceptive effects of galanin in the nucleus accumbens of rats. Neurosci Lett, 2012, 520(1), 43-46.
18. Liu, X. D., Liu, Z., Kong, Q. Y., Zhang, J. J., Wang, Y., & Yu, L. C, Different physiological properties of spontaneous excitatory postsynaptic currents in nucleus accumbens shell neurons between adult and juvenile rats. Neurosci Lett, 2011, 496(2), 80-83.
更多成果信息请见：http://ir.psych.ac.cn/zhangjj@psych.ac.cn

承担科研项目情况：
1.国家自然科学基金面上项目“海马CA1中TET介导的DNA去甲基化调控吗啡成瘾相关记忆形成的机制”，课题编号**，2019.01.01-2022.12.31
2.国家自然科学基金青年科学基金项目“杏仁核调控阿片类药物成瘾记忆再巩固的DNA甲基化机制”，课题编号**，2015.01.01-2017.12.31（已结题）
3.中国科学院心理健康重点实验室自主研究课题面上项目“岛叶调控吗啡成瘾负性情绪记忆再巩固的DNA甲基化机制”，课题编号KLMH2014ZG02，2014.12.1-2016.12.31（已结题）
4.中科院心理所青年人才科研启动项目“外侧杏仁核调控阿片类药物成瘾行为的电生理机制”，课题编号Y2CQ061005，2013.1-2014.12（已结题）

附件：