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北京大学生命科学学院导师教师师资介绍简介-肖俊宇

本站小编 Free考研考试/2020-04-10

肖俊宇 邮  箱:junyuxiao@pku.edu.cn
职  称:研究员
办公室地址:北京市海淀区颐和园路5号,北京大学,吕志和楼,100871
实验室地址:北京市海淀区颐和园路5号,北京大学,吕志和楼,100871


个人简介
科研领域
代表性论文
教育经历:2003 - 2008 , 理学博士 , 密歇根大学
1998 - 2002 , 理学学士 , 北京大学
工作经历:2014 - 至今 , 研究员, 北京大学
2011 - 2013 , 项目科学家, 加州大学圣地亚哥分校
2009 - 2011 , 博士后, 加州大学圣地亚哥分校(导师:Jack Dixon)执教课程:生物化学(本科,主讲)
结构生物学(研究生,参与)

1. Secretory pathway kinases
2. Fatty acid oxidation
3. Structural biology
1.Liang, K., Li, N., Wang, X., Dai, J., Liu, P., Wang, C., Chen, X.W., Gao, N., Xiao, J.* (2018). Cryo-EM structure of human mitochondrial trifunctional protein. Proc Natl Acad Sci U S A 115:7039-7044. (*corresponding author)
2.Zhang, H., Zhu, Q., Cui, J., Wang, Y., Chen, M.J., Guo, X., Tagliabracci, V.S., Dixon, J.E., Xiao, J.* (2018). Structure and evolution of the Fam20 kinases. Nature Communications 9:1218.
3.Liu, Y., Bhowmick, T., Liu, Y., Gao, X., Mertens, H.D.T., Svergun, D.I., Xiao, J.*, Zhang, Y.*, Wang, J.H.*, Meijers, R*. (2018). Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC. Neuron. 97(6):1261-1267.
4.Du, S., Qu, L.J., Xiao, J.* (2018). Crystal structures of the extracellular domains of the CrRLK1L receptor-like kinases ANXUR1 and ANXUR2. Protein Sci. 27:886-892.
5.Sun, X., Li, Y., He, W., Ji, C., Xia, P., Wang, Y., Du, S., Li, H., Raikhel, N., Xiao, J.*, Guo, H.* (2017). Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase. Nature Communications 8:15758.
6.Cui, J., Zhu, Q., Zhang, H., Cianfrocco, M.A., Leschziner, A.E., Dixon, J.E.*, Xiao, J.* (2017). Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding. eLife 6, e23990.
7.Zhu, Q., Venzke, D., Walimbe, A.S., Anderson, M.E., Fu, Q., Kinch, L.N., Wang, W., Chen, X., Grishin, N.V., Huang, N., Yu, L., Dixon, J.E., Campbell, K.P.*, Xiao, J.* (2016). Structure of protein O-mannose kinase reveals a unique active site architecture. eLife 5, e22238.
8.Yu, K., Yu, Y., Tang, X., Chen, H., Xiao, J.*, Su, XD*. (2016). Transcriptome analyses of insect cells to facilitate baculovirus-insect expression. Protein Cell 7:373-82.

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