WU, Yun-Dong (吴云东)Professor
Theoretical Organic and Biological Chemistry
Tel/Fax: 86-
E-Mail:chydwu@ust.hk
Webpage:http://web.pkusz.edu.cn/wu/
1978 - 1981 B.Sc. Lanzhou University
1982 - 1986 PhD, University of Pittsburgh, USA
1987 - 1992 Postdoctoral Fellow, Senior Research Associate, UCLA
1992 - 2007 Assistant ProfessorAssociate ProfessorProfessorChair Professor, Department of Chemistry, HKUST
2011-Present Chair Professor, Peking University Peking University Shenzhen Graduate School

Research Interests:

1) Reaction mechanism and stereochemistry;
2) Development of accurate protein force fields for protein simulations;
3) Drug design based on protein-protein interactions.

Selected Publications:

1. Cheng, G.-J.; Zhang, X.; Chung, L. W.; Xu, L.;Wu, Y.-D,Computational Organic Chemistry: Bridging Theory and Experiment in Establishing the Mechanisms of Chemical Reactions.J Am Chem Soc2015,137(5),1706-1725. ( Invited Perspective)
2. Wang, Y.; Hu, X.-J.; Zou, X.-D.; Wu, X.-H.; Ye, Z.-Q.;Wu, Y.-D.WDSPdb: A Database for WD40-repeat Proteins,Nucl Acids Res2015,43, DOI: 10.1093/nar/gku1023.
3. Jiang, F.;Wu, Y.-D,Folding of Fourteen Small Proteins with a Residue-Specific Force Field and Replica-Exchange Molecular Dynamics.J Am Chem Soc2014,136, 9536-9539.
4. Yang, Y.-F.; Cheng, G.-J.; Liu, P.; Leow, D.; Sun, T.-Y.; Chen, P.; Zhang, X.; Yu, J.-Q.;Wu, Y.-D.; Houk, K. N, Palladium-Catalyzed Meta-Selective C–H Bond Activation with a Nitrile-Containing Template: Computational Study on Mechanism and Origins of Selectivity.J Am Chem Soc2014,136, 344-355.
5. Cheng, G.-J.; Yang, Y.-F.; Liu, P.; Chen, P.; Sun, T.-Y.; Li, G.; Zhang, X.; Houk, K. N.; Yu, J.-Q.;Wu, Y.-D,Role of N-Acyl Amino Acid Ligands in Pd(II)-Catalyzed Remote C–H Activation of Tethered Arenes.J Am Chem Soc2014,136, 894-897.

Honors and Awards:

1. Scientific Board member, World Association of Theoretical and Computational Chemists (WATOC), 1999-;
2. Vice-President, Asian Pacific Association of Theoretical and Computational Chemistry (APATCC), 2012-;
3. Member, the Chinese Academy of Science, 2005;
4. Fellow, Hong Kong Institute of Science, 2011;
5. Wong Kuen Shing Education Foundation Exchange Scholar Award, 1998;
6. National Natural Science Award of China, 1999, 2013;
7. Croucher Senior Research Fellowship Award (Croucher Award), 2000;
8. Outstanding Young Investigator Award, National Natural Science Foundation of China, 2002-2006;
9. Thomson-Reuters Research Fronts Award, 2008;
10. School of Science Teaching Award, HKUST, 2009;
11. Anhui Province Science Award of China, 2012;
12. Robert S. Mulliken Lecture at University of Georgia, 2013;
13. Fukui Medal, The Asia-Pacific Association of Theoretical & Computational Chemists (APATCC) 2014.
14. Achievement Award for Physical Organic Chemistry, The Chinese Chemical Society, 2015.