Xinyuan Fan
PhD, Research Associate Professor
Email：xinyuanfan@pku.edu.cn
EDUCATION2010-2014
PhD, Institute of Chemical Research of Catalonia, Tarragona, Spain
2013-2013
visiting scholar, University of Pennsylvania, Philadelphia, USA
2003-2010
B.S & M.S., Lanzhou University, Lanzhou, China
EXPERIENCE2019-present, Research Associate Professor, College of Chemistry and Molecular Engineering, Peking University
2017-2019, Associate Professor, Nanjing Tech University
2015-2017, Postdoctoral Fellow, Peking-Tsinghua Center for Life Sciences, Peking University
SELECTED PUBLICATIONS(1)Fan, X.*; Gong, X.#; Ma, M.#; Wang, R.; Walsh, P. J.* “Visible Light-Promoted CO2 Fixation with Imines to Synthesize Diaryl α-Amino Acids”, Nat. Comm.2018, DOI: 10.1038/s41467-018-07351-2.
(2) Wang, R.; Ma, M.; Gong, X.;Fan, X.*; Walsh, P. J.* “Reductive Cross-Coupling of Aldehydes and Imines Mediated by Visible Light Photoredox Catalysis”, Org. Lett.2018, DOI: 10.1021/acs.orglett.8b03394.
(3) Wang, R.; Ma, M.; Gong, X.;Fan, X.*; Walsh, P. J.* “Visible Light-Mediated Umpolung Reactivity of Imines: Ketimine Reductions with Cy2NMe and Water”, Org. Lett.2018, 2433.
(4)Fan, X.; Walsh, P. J.* “Chelation-Controlled Additions to Chiral α- and β-Silyloxy, α-Halo, and β-Vinyl Carbonyl Compounds”, Acc. Chem. Res.2017, 50, 2389.
(5)Fan, X.; Li, J.; Chen, P.* “Bioorthogonal Chemistry in Living Animals”, Natl. Sci. Rev.2017, 4, 300.
(6)Fan, X.; Ge, Y.; Lin, F.; Yang, Y.; Zhang, G.; Ngai, W.; Lin, Z.; Zheng, S.; Wang, J.; Zhao, J.; Li, J.; Chen, P.* “Optimized Tetrazine Derivatives for Rapid Bioorthogonal Decaging in Living Cells”, Angew. Chem. Int. Ed.2016, 55, 14046.
(7) Ge, Y.#;Fan, X.#; Chen, P.* “A genetically encoded multifunctional unnatural amino acid for versatile protein manipulations in living cells”, Chem. Sci.2016, 7, 7055. (# Co-first author).
(8)Fan, X.; Rodríguez-Escrich, C.; Wang, S.; Sayalero, S.; Pericàs, M. A.* “Highly Enantioselective Cross-Aldol Reactions of Acetaldehyde Mediated by a Dual Catalytic System Operating under Site Isolation”, Chem. Eur. J.2014, 20, 13089.
(9)Fan, X.; Rodríguez-Escrich, C.; Sayalero, S.; Pericàs, M. A.* “Paraldehyde as an Acetaldehyde Precursor in Asymmetric Michael Reactions Promoted by Site-Isolated Incompatible Catalysts”, Chem. Eur. J.2013, 19, 10814.
(10)Fan, X.; Sayalero, S.; Pericàs, M. A.* “Asymmetric α-Amination of Aldehydes Catalyzed by PS-Diphenylprolinol Silyl Ethers: Remediation of Catalyst Deactivation for Continuous Flow Operation”, Adv. Synth. Catal.2012, 354, 2971.