袁谷教授化学生物学,化学生物质谱学，有机合成

电话：62754049(O)传真：62751708
电子信箱:guyuan@pku.edu.cn


学术简历:1992年在日本高知大学获博士学位
主讲课程:1.有机化合物的结构鉴定(本科生)2.表征技术-波谱学(研究生)研究领域和兴趣:1.DNA识别分子的合成及活性研究2.化学生物质谱学


BindingmodelforhairpinpolyamideandDNA
SelectedPublications1.LiHH,ZhouJ,TangFL,YuanG*,Investigationofnoncovalentcomplexesbetweenbeta-cyclodextrinandpolyamideacidscontainingN-methylpyrroleandN-methylimidazolebyelectrosprayionizationmassspectrometry,JournaloftheAmericanSocietyforMassSpectrometry,17(1),9-14,2006.
2.LiHH,YuanG*,ElectrosprayionizationmassspectralcharacteristicsandfragmentationmechanismsofAngiotensinIIanditsanalogues,InternationalJournalofMassSpectrom,252(1):54-60,2006.
3.LiHH,YuanG*,Investigationofnon-covalentcomplexesofHIV-1promoterDNAandpolyamidescontainingN-methylpyrrolebyelectrosprayionizationmassspectrometry,RapidCommun.MassSpectrom.,20(11):1736-1740,2006.
4.LiuD,YuanG*,HuJM,Synthesisandphoto-inducedDNAcleavingactivitiesofconjugatesofhalophenylderivativeandpolyamidecontainingN-methylimidazoles,JournalofPhotochemPhotobiologyB-Biology,82(3):187-193,2006.
5.WangJ,YuanG*,Synthesisofhomoallylicalcoholsfromketonesinwater,SyntheticCommunications,36(3):401-4052006.
6.ZhouJ,YuanG*,AnalysisofnoncovalentcomplexesbetweenhumantelomericDNAandpolyamidescontainingN-methylpyrroleandN-methylimidazolebyusingelectrosprayionizationmassspectrometry,Chemistry-AEuropeanJournal,11:1157,2005.
7.WangJ,MiaoXP,YuanG*,SelectivecarbonylpropargylationmediatedbySnCl2/NiCl2-KIinwaterAustralianJournalofChemistry,58(8):611-614,2005.
8.WangJ,ZhouJ,YuanG*,ElectrospraynegativeionizationmassspectrometryofpolyamidescontainingN-methylpyrroleandN-methylimidazole,JournalofMassSpectrom.40:688,2005.
9.LiuDan,ZhouJiang,YuanG*,ElectrosprayionizationmassspectralcharacteristicsandfragmentationmechanismsofnovelphotoinducedDNA-cleavingagentsformedasconjugatesofhaloarenesandpolyamidescontainingN-methylimidazole,RapidCommun.MassSpectrom.,18:2770,2004.
10.ZhouJ,YuanG*,ElectrosprayionizationmassspectrometricanalysisofnoncovalentcomplexesbetweenDNAand…,RapidCommun.MassSpectrom.18,1519,2004.
11.YuanG*,ZhouJ,ElectrosprayionizationmassspectralfragmentationmechanismsofDNA-recognizing…,RapidCommun.MassSpectrom.18,1397,2004.
12.WangJ,YuanG*,etal.,Novelultrasonication-assistedcarbonylallylationmediatedbySnCl2inwater,ChemistryLetters,33(3),286,2004.
13.ZhuC.G.,YangX.L.,CaoS.X.,YuanG,etal.,Monitoringthesyntheticreactionofapolyamide/peptide,…,RapidCommun.MassSpectrom.,17,825(2003).
14.TangF.L.,YuanG*,WangJ,SynthesisandphotoinducedDNAcleavingactivityofhairpinpolyamide-chlorobenzenesulfonylconjugate,Photochem.Photobiol.78,175(2003).
15.YuanG*,TangF.L.,SynthesisofDNA-recognizingpolyamidescontainingN-methylpyrroleandN-methylimidazole,Arkivoc,32,(2003).
16.YuanG*,etal,FragmentationmechanismsofpolyamidescontainingN-methylpyrroleandN-methylimidazolebyelectrosprayionizationtandemmassspectrometry,RapidCommun.MassSpectrom.17,2015(2003).
17.YuanG*,XiaoJ.H.,etal,SynthesisofpolyamidescontainingN-methylpyrroleandN-methylimidazoleandtheiranticanceractivity,ArchivesofPharmacalResearch,25,585(2002).
18.TangF.L.,WangJ.,LiuD.,YuanG*,etal,Electrosprayionizationtandemmassspectrometriccharacteristicsandfragmentationmechanismsofdistamycinanalogues,RapidCommun.MassSpectrom.,16，1035(2002).
19.YuanG*,YanJ.C.,Aformulaforcalculationofdoublebondpositionoftetradecenolsbasedonmassspectraofdimethyldisulfidederivatives,RapidCommun.MassSpectrom.,16,11(2002).
20.XiaoJ.H.,YuanG*,etal,AconvenientmethodforthesynthesisofDNA-recognizingpolyamidesinsolution,J.Org.Chem.,65,5506(2000).
21.YuanG*,HeM.Y.,WangG.J.,WangQ.B.,Electronimpactmassspectralcharacteristicsandfragmentationpathwaysofisomerictetradecadien-1-ols,RapidCommun.MassSpectrom.,13,1(1999).
22.YuanG*,XiaoJ.H.,etal,Similaritybetweenmassspectraofisomericalkenolsandtheiracetates,RapidCommun.MassSpectrom.,12,1287(1998).
23.YuanG*,etal,Similaritybetweenmassspectraofdouble-bondpositionalisomersoftetradecen-1-olsandtheiracetates,RapidCommun.MassSpectrom.,11,1699(1997).
24.YuanG*,Identificationoftheconfigurationofsexpheromoneswithaconjugateddoublebondbyfuzzysimilarityanalysisofchemicalshiftsofolefiniccarbons,FreseniusJ.Anal.Chem.,354,241(1996).

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