中文关键词:室温碱促进酰胺化喹啉酰胺绿色环保 英文关键词:Room Temperature, Base-Promoted, Amidation, Quinolinamide, Environmental-Friendly 基金项目:国家自然科学基金项目（21672046, 21372054）

作者	单位	E-mail
马莲凤	哈尔滨工业大学威海海洋科学与技术学院	15165186105@163.com
马莲凤 李惠静 吴彦超	哈尔滨工业大学(威海)海洋科学与技术学院 威海 264209
李惠静	哈尔滨工业大学威海海洋科学与技术学院
吴彦超	哈尔滨工业大学威海海洋科学与技术学院	morland_m@163.com

摘要点击次数:1116 全文下载次数:0 中文摘要: 从经济性和环保性考虑，本文以喹啉甲醛和芳香胺为原料，室温下利用廉价易处理的碱作为促进剂成功合成一系列喹啉酰胺衍生物，对所得产物进行了表征，考察了不同溶剂、碱和底物摩尔比对反应的影响，获得了优化的反应条件，并在文末提出了可能的反应机理。该反应具有条件温和、处理简单、收率较好、绿色环保等特点。 英文摘要: Based on the consideration of economy and environmental protection, a new method for the synthesis of a series of quinolinamide derivatives from quinolinecarboxaldehyde and aromatic amines has been developed by using an inexpensive and easy-to-handle base as the promoter at room temperature.The synthesized products were all characterized. The effects of solvents, bases and substrates molar ratios on the reaction were examined to obtain the optimal reaction conditions, and a possible reaction mechanism was proposed. The reaction possesses many advantages such as mild conditions, simple treatment, good yields, and environmental friendliness. 查看全文查看/发表评论下载PDF阅读器 相关附件：版权转让声明书附件1 -->