Effective and precise adenine base editing in mouse zygotes

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Puping Liang1,2,,
Hongwei Sun1,
Xiya Zhang1,
Xiaowei Xie1,
Jinran Zhang1,
Yaofu Bai1,
Xueling Ouyang1,
Shengyao Zhi1,
Yuanyan Xiong1,
Wenbin Ma1,
Dan Liu4,
Junjiu Huang1,2,3,,
Zhou Songyang1,2,3,4,
1 Key Laboratory of Gene Engineering of the Ministry of Education, Guangzhou Key Laboratory of Healthy Aging Research and SYSU-BCM Joint Research Center, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China;
2 Key Laboratory of Reproductive Medicine of Guangdong Province, School of Life Sciences and the First Affiliated Hospital, Sun Yatsen University, Guangzhou 510275, China;
3 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China;
4 Verna and Marrs Mclean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA

Abstract

PDF全文下载地址:

http://www.protein-cell.org/article/exportPdf?id=ec1fb0a1-790d-4f62-810c-33f33a094e33&language=en

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