Phytochemical variation among the traditional Chinese medicine Mu Dan Pi from Paeonia suffruticosa (tree peony)
作 者：Li SS, Wu Q, Yin DD, Feng CY, Liu ZA*, Wang LS*
影响因子:3.205
刊物名称:Phytochemistry
出版年份:2018
卷:146期: 页码:16-24
文章摘要:MuDan Piis atraditional Chinese medicineused to treat inflammation, cancer, allergies, diabetes, angiocardiopathy, and neurodegenerative diseases. In this study, themetabolomevariation within Mu Dan Pi collected from 372 tree peonycultivarswas systematically investigated. In total, 42 metabolites were identified, comprising of 14 monoterpeneglucosides, 11tannins, 8paeonols, 6flavonoids, and 3phenols. All cultivars revealed similar metabolite profiles, however, they were further classified into seven groups on the basis of their varying metabolite contents by hierarchical cluster analysis. Traditional cultivars for Mu Dan Pi were found to have very low metabolite contents, falling into clusters I and II. Cultivars with the highest amounts of metabolites were grouped in clusters VI and VII. Five potential cultivars, namely, ‘Bai Yuan Qi Guan’, ‘Cao Zhou Hong’, ‘Da Zong Zi’, ‘Sheng Dan Lu’, and‘Cheng Xin’, with high contents of monoterpeneglycosides, tannins, and paeonols, were further screened. Interestingly, the majority of investigated cultivars had relatively higher metabolite contents compared to the traditional medicinal tree peony cultivars.