基本信息
王猛男博导中国科学院天津工业生物技术研究所
电子邮件： wangmeng@tib.cas.cn
通信地址： 天津空港经济区西七道32号
邮政编码：

研究领域

招生信息
招生专业071005-微生物学
071010-生物化学与分子生物学
081703-生物化工

招生方向合成生物学，生物学自动化，高通量筛选，天然产物生物合成


教育背景2005-09--2009-12美国锡拉丘兹大学化学系博士学位
2001-09--2005-05浙江大学化学系学士学位
2001-09--2005-05浙江大学生物信息学第二学位

学历
学位

工作经历
工作简历2015-05~现在,中国科学院天津工业生物技术研究所,研究员
2010-02~2015-04,伊利诺伊大学厄巴纳香槟分校,博士后

社会兼职

教授课程

专利与奖励
奖励信息
专利成果

出版信息
发表论文（1）Directed evolution of xylose specific transporters to facilitate glucose-xylose co-utilization,Biotechnology and Bioengineering,2016,第1作者
（2）Identification of an important motif that controls the activity and specificity of sugar transporters,Biotechnology and Bioengineering,2016,第1作者
（3）Combined and Iterative Use of Computational Design and Directed Evolution for Protein-Ligand Binding Design,Methods in Molecular Biology,2016,第1作者
（4）Development of a Synthetic Malonyl-CoA Sensor in Saccharomyces cerevisiae for Intracellular Metabolite Monitoring and Genetic Screening. ACS synthetic biology,ACS synthetic biology,2015,第3作者
（5）Design and engineering of intracellular-metabolite-sensing/regulation gene circuits in Saccharomyces cerevisiae,Biotechnology and Bioengineering,2015,第1作者
（6）Characterization and engineering of the adenylation domain of a NRPS-like protein: a potential biocatalyst for aldehyde generation,ACS catalysis,2014,第1作者
（7）Resorcylic acid lactone biosynthesis relies on a stereo-tolerant macrocyclizing thioesterase,Organic Letters,2014,第3作者
（8）Aryl-aldehyde formation in fungal polyketides: Discovery and characterization of a distinct biosynthetic mechanism,Chemistry & Biology,2013,第1作者
（9）Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster,Nature Communications,2013,第4作者
（10）6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective,Organic Letters,2012,第2作者
（11）Biocatalyst development by directed evolution.,Bioresource Technology,2011,第1作者
（12）Microbial synthesis of drugs and fuels via synthetic biology,Chinese Bulletin of Life Sciences,2011,第1作者
（13）A thioesterase from an iterative fungal polyketide synthase shows macrocyclization and cross coupling activity and may play a role in controlling iterative cycling through product offloading,Biochemistry,2009,第1作者
（14）Polyketide synthase thioesterases catalyze rapid hydrolysis of peptidyl thioesters,Bioorganic and Medicinal Chemistry Letter,2009,第1作者
（15）Examining the role of hydrogen bonding interactions in the substrate specificity for the loading step of polyketide synthase thioesterase domains,Biochemistry,2008,第1作者
（16）Synthesis of metronidazole esters and their monosaccharide ester derivatives,Enzyme Microbiology and Technology,2006,第2作者

发表著作

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参与会议

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指导学生