基本信息
曲广波男硕导中国科学院生态环境研究中心
电子邮件： gbqu@rcees.ac.cn
通信地址： 北京市海淀区双清路18号
邮政编码： 100085
部门/实验室：人事教育处
研究领域

招生信息
招生专业0703J1-纳米科学与技术
0703Z1-化学生物学
100102-免疫学

招生方向环境污染与健康
新型污染物分析
污染物与生物效应


教育背景2008-09--2011-06中国科学院生态环境研究中心理学博士
2000-09--2004-07黑龙江大学生命科学学院理学学士

学历
学位

工作经历
工作简历2015-03~2015-05,美国迈阿密大学米勒医学院,访问，博士后
2015-01~现在,中国科学院生态环境研究中心,副研究员
2014-01~2015-02,美国印第安纳大学医学院,访问，博士后
2011-07~2014-12,中国科学院生态环境研究中心,助理研究院
2010-07~2011-02,香港科技大学化学系,研究助理
2005-09~2008-07,山东大学药学院,医学硕士

社会兼职

教授课程纳米毒理学


专利与奖励
奖励信息
专利成果

出版信息
发表论文（1）High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples,Trends in Analytical Chemistry,2019-02,通讯作者
（2）Improved Biocompatibility of Black Phosphorus Nanosheets by Chemical Modification,Angewandte Chemie International Edition,2017,第1作者
（3）Determining the Cytotoxicity of Rare Earth Element Nanoparticles in Macrophages and the Involvement of Membrane Damage,Environmental Scicence & Technology,2017,通讯作者
（4）Structure-Dependent Hematological Effects of Per- and Polyfluoroalkyl Substances on Activation of Plasma Kallikrein-Kinin System Cascade,Environmental Science & Technology,2017,第3作者
（5）Distinct toxicological characteristics and mechanisms of Hg(2+) and MeHg in Tetrahymena under low concentration exposure,Aquatic Toxicology,2017,第2作者
（6）Identification of Emerging Brominated Chemicals as the Transformation Products of Tetrabromobisphenol A (TBBPA) Derivatives in Soil,Environmental Science & Technology,2017,通讯作者
（7）Sensitive immunoassay for simultaneous determination of tetrabromobisphenol A bis(2-hydroxyethyl) ether and tetrabromobisphenol A mono(hydroxyethyl) ether: An effective and reliable strategy to estimate the typical tetrabromobisphenol A derivative and byproduct in aquatic environments,Environmental Pollution,2017,通讯作者
（8）A crucial role of heme-regulated eIF2 alpha kinase in maintaining cytoskeletal meshwork under an oxygen deficient condition,Science Bulletin,2017,第1作者
（9）Recent advances in the analysis of TBBPA/TBBPS, TBBPA/TBBPS derivatives and their transformation products,Trends in Analytical Chemistry,2016,第1作者
（10）Graphene enhances cellular proliferation through activating EGFR,Journal of Agricultural and Food Chemistry,2016,第6作者
（11）The potential neurotoxicity of emerging tetrabromobisphenol A derivatives based on rat pheochromocytoma cells,Chemosphere,2016,第5作者
（12）Carbon nanotubes stimulate synovial inflammation through inducing systemic pro-inflammatory cytokines,Nanoscale,2016,第3作者
（13）Tetrabromobisphenol-A/S and Nine Novel Analogs in Biological Samples from the Chinese Bohai Sea: Implications for Trophic Transfer,Environmental science & technology,2016,第2作者
（14）Exposure, Tissue Biodistribution, and Biotransformation of Nanosilver,NanoImpact,2016,第3作者
（15）Silver ion post-column derivatization electrospray ionization mass spectrometry for determination of tetrabromobisphenol A derivatives in water samples,RSC Advances,2015,第3作者
（16）Identification of two novel brominated contaminants in water samples by ultra-high performance liquid chromatography-Orbitrap Fusion Tribrid mass spectrometer,Journal of Chromatography A,2015,第2作者
（17）Reactive extractive electrospray ionization tandem mass spectrometry for sensitive detection of tetrabromobisphenol A derivatives,Analytica chimica acta,2014,第4作者
（18）Graphene Oxide Induces Toll-like Receptor 4 (TLR4)-Dependent Necrosis in Macrophages,ACS Nano,2013,第1作者
（19）Identification of Tetrabromobisphenol A Allyl Ether and Tetrabromobisphenol A 2,3-Dibromopropyl Ether in the Ambient Environment near a Manufacturing Site and in Mollusks at a Coastal Region,Environmental Science & Technology,2013,第1作者
（20）Evaluation of the biological fate and the transport through biological barriers of nanosilver in mice,Current pharmaceutical design,2013,第2作者
（21）The capability of quantum dots in crossing the placental barrier and the potential influence on erythrocytes,Journal of nanoscience and nanotechnology,2013,第3作者
（22）Quantum dots (QDs) restrain human cervical carcinoma HeLa cell proliferation through inhibition of the ROCK-c-Myc signaling,Integrative Biology,2013,第1作者
（23）Downregulation of ubiquitin E3 ligase TNF receptor-associated factor 7 leads to stabilization of p53 in breast cancer,Oncology reports,2013,第4作者
（24）Characterization of the interaction between cadmium and chlorpyrifos with integrative techniques in incurring synergistic hepatoxicity,PloS one,2013,第2作者
（25）Simultaneous determination of five estrogens and four androgens in water samples by online solid-phase extraction coupled with high-performance liquid chromatography–tandem mass spectrometry,Journal of chromatography A,2013,第3作者
（26）A protective role of heme-regulated eIF2α kinase in cadmium-induced toxicity in erythroid cells,Food and chemical toxicology,2013,第4作者
（27）Influence of e-waste dismantling and its regulations: temporal trend, spatial distribution of heavy metals in rice grains, and its potential health risk,Environmental science & technology,2013,第4作者
（28）The ex vivo and in vivo biological performances of graphene oxide and the impact of surfactant on graphene oxide's biocompatibility,Journal of Environmental Sciences,2013,第1作者
（29）Cytotoxicity of quantum dots and graphene oxide to erythroid cells and macrophages,Nanoscale research letters,2013,第1作者
（30）Silver nanoparticles induced RNA polymerase-silver binding and RNA transcription inhibition in erythroid progenitor cells,ACS nano,2013,第4作者
（31）Quantum dots impair macrophagic morphology and the ability of phagocytosis by inhibiting the Rho-associated kinase signaling,Nanoscale,2012,第1作者
（32）Sample preparation method for the speciation of polybrominated diphenyl ethers and their methoxylated and hydroxylated analogues in diverse environmental matrices,Talanta,2012,第4作者
（33）Temporal trends (2005–2009) of PCDD/Fs, PCBs, PBDEs in rice hulls from an e-waste dismantling area after stricter environmental regulations,Chemosphere,2012,第4作者
（34）Identification of Tetrabromobisphenol A Diallyl Ether as an Emerging Neurotoxicant in Environmental Samples by Bioassay-Directed Fractionation and HPLC-APCI-MS/MS,Environmental Science & Technology,2011,第1作者
（35）Detection of tris-(2, 3-dibromopropyl) isocyanurate as a neuronal toxicant in environmental samples using neuronal toxicity-directed analysis,Science China Chemistry,2011,第1作者
（36）The effect of multiwalled carbon nanotube agglomeration on their accumulation in and damage to organs in mice,Carbon,2009,第1作者

发表著作

科研活动
科研项目（ 1 ） 稀土氧化物纳米材料对DNA甲基化和羟 甲基化的调控机理及其毒性研究, 主持,国家级,2016-01--2019-12
（ 2 ） 纳米银对巨噬细胞毒性的机理研究, 主持,国家级,2013-01--2015-12
（ 3 ） 典型污染物的环境暴露与健康危害机制, 参与,部委级,2014-07--2019-07
（ 4 ） 典型人工纳米材料的水环境过程、生物效应及其调控研究, 参与,国家级,2014-01--2019-12
（ 5 ） 化学环境污染与健康, 主持,国家级,2018-01--2020-12

参与会议（1）Neural toxicity assay-directed analysis: application in novel pollutant identification2012-09-23


合作情况
项目协作单位

指导学生现指导学生
李平硕士研究生071300-生态学
王易硕士研究生085229-环境工程