基本信息
John Seymour Heslop Harrison男博导中国科学院华南植物园
电子邮件： phh4@le.ac.uk
通信地址： 中国科学院华南植物园五号实验楼106
邮政编码： LE1 7RH

研究领域1. 普通栽培燕麦基因组多样性和演化。设计c. 3 Mbp的合成寡核苷酸探针库，鉴定六倍体普通栽培燕麦染色体，A、D、C基因组间异位。
2. 多倍体作物基因组互作与机制研究。研究对象芸苔属(Brassica) 二倍体和四倍体作物物种，采用染色质免疫共沉淀(ChIP)、生物信息学与显微镜技术，探讨多倍体中基因控制如何发生的，及如何控制表达和染色质修饰。
3. 系统发育和多样性研究。研究对象选择芭蕉目芭蕉属(Musa)、姜目凹唇姜属(Boesenbergia)、象腿蕉属(Ensete)、姜属(Zingiber)和Stelitzia属，探讨染色体、基因组演化和植物多样性问题。
4. 基因组分析工具开发。关注两个层次问题：在转座子和卫星DNA水平的重复序列差异，挖掘物种水平基因组结构和序列变化；开发新的分析工具，拟解决二歧分支假说为基础的计算机程序缺陷，为多倍体物种谱系关系和杂种基因组起源提供证据。




招生信息
招生专业071007-遗传学
071001-植物学

招生方向植物遗传育种学, 植物分子遗传学


教育背景1980-10--1983-02英国剑桥大学博士
1977-09--1980-06英国威尔士大学硕士

学历
学位

工作经历
工作简历2000-11~现在,英国莱斯特大学,教授
1990-06~2000-09,英国John Innes Center,首席科学家
1986-10~1990-05,英国农业研究理事会植物学科学研究所,科学家

社会兼职2008-01-01-今,Annals of Botany主编, Chief-in-Editor
2004-01-01-今,欧洲细胞遗传学协会理事会理事, 理事


教授课程

专利与奖励
奖励信息
专利成果

出版信息


Full list please browser https://www.le.ac.uk/biology/phh4/titles.html
348. Escudeiro A, Adega F, Robinson TJ, Heslop-Harrison JS, Chaves R. 2019. Conservation, divergence and functions of centromeric satellite DNA families in the Bovidae. Genome Biology and Evolution (in press March 2019) https://doi.org/10.1093/gbe/evz061
347. Liu Q, Li XY, Zhou XY, Li MZ, Zhang FJ, Schwarzacher T, Heslop-Harrison JS. 2019. The DNA landscape in Avena: Chromosome and genome evolution defined by major repetitive DNA classes in whole-genome sequence reads. BMC Plant Biology 19: 226.
346. Escudeiro A, Adega F, Robinson TJ, Heslop-Harrison JS, Chaves R. 2019. Conservation, divergence and functions of centromeric satellite DNA families in the Bovidae. Genome Biology and Evolution (in press March 2019) https://doi.org/10.1093/gbe/evz061
345. Escudeiro A, Ferreira D, Mendes-da-Silva A, Heslop-Harrison JS, Adega F, Chaves R. 2019. Bovine satellite DNAs–a history of the evolution of complexity and its impact in the Bovidae family. European Zoological Journal 86: 20-37.
344. Sepsi A, Fábián A, J?ger K, Heslop-Harrison JS, Schwarzacher T. 2018. ImmunoFISH: simultaneous visualisation of proteins and DNA sequences gives insight into meiotic processes in nuclei of grasses. Frontiers in Plant Science 9: article 1193. https://doi.org/10.3389/fpls.2018.00717
343. Velmurugan J, Milbourne D, Connolly V, Heslop-Harrison JS, Anhalt UC, Lynch MB, Barth S. 2018. An immortalized genetic mapping population for perennial ryegrass: a resource for phenotyping and complex trait mapping. Frontiers in Plant Science 9: article 717. https://doi.org/10.3389/fpls.2018.00717
342. Mhiret WN, Heslop-Harrison JS. 2018. Biodiversity in Ethiopian linseed (Linum usitatissimum L.): molecular characterization of landraces and some wild species. Genetic Resources and Crop Evolution 65: 1603-1614. https://doi.org/10.1007/s10722-018-0636-3 and author version https://molcyt.wordpress.com/?p=1301&preview=true
341. Mustafa SI, Schwarzacher T, Heslop-Harrison JS. 2018. Complete mitogenomes from Kurdistani sheep: abundant centromeric nuclear copies representing diverse ancestors. Mitochondrial DNA Part A https://doi.org/10.1080/**.2018.** (publisher – or limited free publisher link http://www.tandfonline.com/eprintREMOVE/YSxE33mSJiBMVEuMXIyv/full) AND Mustafa et al_2018 AuthorVersion
341.Mustafa SI, Schwarzacher T, Heslop-Harrison JS. 2018.Complete mitogenomes from Kurdistani sheep: abundant centromeric nuclear copies representing diverse ancestors.Mitochondrial DNA Part Ahttps://doi.org/10.1080/**.2018.**(publisher – or limited free publisher link http://www.tandfonline.com/eprintREMOVE/YSxE33mSJiBMVEuMXIyv/full) ANDMustafa et al_2018 AuthorVersion
340.Heslop-Harrison JS. 2017.Morphology, adaptation and speciation.Annals of Botany120(7): 621-624.https://doi.org/10.1093/aob/mcx130
339.Gouveia JG, Wolf IR, Vilas-Boas LA, Heslop-Harrison JS, Schwarzacher T, Dias AL. 2017.Repetitive DNA in the catfish genome: rDNA, microsatellites, and Tc1-mariner transposon sequences in Imparfinis species (Siluriformes, Heptapteridae).Journal of Heredity108(6): 650-657.https://doi.org/10.1093/jhered/esx065
338.Nouroz FA, Noreen SH, Heslop-Harrison JS. 2017.Identification and evolutionary dynamics of CACTA DNA transposons in Brassica.Pakistan Journal of Botany49(2): 789-798.https://www.pakbs.org/pjbot/PDFs/49(2)/51.pdf
337.Alix K, Gérard PR, Schwarzacher T, Heslop-Harrison JS. 2017.Polyploidy and interspecific hybridisation: partners for adaptation, speciation and evolution in plants.Annals of Botany120: 183-194.https://dx.doi.org/10.1093/aob/mcx079
336.Nouroz F, Noreen S, Khan MF, Ahmed S, Heslop-Harrison JS. 2017.Identification and characterization of mobile genetic elements LINEs fromBrassicagenomes.Gene627: 94-105.https://doi.org/10.1016/j.gene.2017.06.015
335. Otwe EP, Agyirifo DS, Galyuon IK, Heslop-Harrison JS. 2017.Molecular Diversity in some Ghanaian Cowpea [Vigna unguiculataL.(Walp)] Accessions.Tropical Plant Biology10 (2-3):57-67.https://dx.doi.org/10.1007/s12042-017-9184-9
334. Nouroz F, Noreen S, Ahmad H, Heslop-Harrison JS. 2017.The landscape and structural diversity of LTR retrotransposons inMusagenomes.Molecular Genetics and Genomics292(5):1051-1067.https://dx.doi.org/10.1007/s00438-017-1333-1
333. Salih RHM, Majesky L, Schwarzacher T, Gornall R, Heslop-Harrison P. 2017. Complete chloroplast genomes from apomictic Taraxacum(Asteraceae): identity and variation between three microspecies. PLoS One12(2): e**. https://dx.doi.org/10.1371/journal.pone.**







发表论文（1）牛科卫星DNA进化历史及其对Bovidae家族的影响,Bovine satellite DNAs–a history of the evolution of complexity and its impact in the Bovidae family,European Zoological Journal,2019,第4作者
（2）牛科着丝粒卫星DNA家族的分化及功能,Conservation, divergence and functions of centromeric satellite DNA families in the Bovidae,Genome Biology and Evolution,2019,第4作者
（3）燕麦属重复序列结构特征,The repetitive DNA landscape in Avena (Poaceae): chromosome and genome evolution defined by major repeat classes in whole-genome sequence reads,BMC Plant Biology,2019,通讯作者
（4）埃塞俄比亚亚麻籽生物多样性,Biodiversity in Ethiopian linseed (Linum usitatissimum L.): molecular characterization of landraces and some wild species,Genetic Resources and Crop Evolution,2018,第2作者
（5）蛋白质和DNA序列的同时可视化提供胞核减数分裂证据,ImmunoFISH: simultaneous visualisation of proteins and DNA sequences gives insight into meiotic processes in nuclei of grasses,Frontiers in Plant Science,2018,第4作者
（6）蛋白质和DNA序列模拟可视化提供胞核减数分裂证据,ImmunoFISH: simultaneous visualisation of proteins and DNA sequences gives insight into meiotic processes in nuclei of grasses,Frontiers in Plant Science,2018,第4作者
（7）多年生黑麦草遗传图谱,An immortalized genetic mapping population for perennial ryegrass: a resource for phenotyping and complex trait mapping,Frontiers in Plant Science,2018,第4作者
（8）埃塞俄比亚亚麻籽生物多样性,Biodiversity in Ethiopian linseed (Linum usitatissimum L.): molecular characterization of landraces and some wild species,Genetic Resources and Crop Evolution,2018,第2作者
（9）Kurdistani羊全线粒体基因组序列,Complete mitogenomes from Kurdistani sheep: abundant centromeric nuclear copies representing diverse ancestors,Mitochondrial DNA Part A,2018,第3作者
（10）六倍体小麦花粉减数分裂过程CENH3蛋白与着丝粒形态建成动力学过程,CENH3 morphogenesis reveals dynamic centromere associations during synaptonemal complex formation and the progression through male meiosis in hexaploid wheat,Plant Journal,2017,第3作者
（11）芭蕉属基因组反转录转座子结构多样性,The landscape and structural diversity of LTR retrotransposons in Musa genomes,Molecular Genetics and Genomics,2017,通讯作者
（12）芸薹属基因组重复序列LINE元件结构特征研究,Identification and characterization of mobile genetic elements LINEs from Brassica genomes,Gene,2017,第5作者
（13）多倍体种间杂交模式及多样性,Polyploidy and interspecific hybridisation: partners for adaptation, speciation and evolution in plants,Annals of Botany,2017,第4作者
（14）鲶鱼基因组重复序列研究,Repetitive DNA in the catfish genome: rDNA, microsatellites, and Tc1-mariner transposon sequences in Imparfinis species (Siluriformes, Heptapteridae),Journal of Heredity,2017,第4作者
（15）欧盟安全条例-勿使伪科学合法化,EU safety regulations: Don’t mar legislation with pseudoscience,Nature,2016,第4作者
（16）织物比较基因组结构-从序列到遗传标记,Comparative genome organization in plants: from sequence and markers to chromatin and chromosomes,Plant Cell,2000,第1作者

发表著作（1）原位杂交实验,Practical in situ Hybridization,BIOS Scientific Publishers,2000-07,第2作者


科研活动
科研项目（ 1 ） 华南植物园海外知名项目, 主持,市地级,2018-05--2023-08

参与会议（1）Chromosome and Genome Evolution in Plants and Animals布拉格染色体研究国际会议2018-09-01
（2）Molecular cytogenetics and genomics of Brassica俄罗斯细胞遗传学家协会会议2018-08-01
（3）Building partnerships for development, several locations与哥伦比亚伙伴关系简历与发展2018-06-13
（4）香港浸会大学基金项目评审员香港浸会大学基金项目评审2018-04-25
（5）Mendel Seminar孟德尔研讨会2018-04-10


合作情况
项目协作单位

指导学生
博士生王梓维
硕士生周书玉