基本信息

胡振华女博导中国科学院自动化研究所
电子邮件： zhenhua.hu@ia.ac.cn
通信地址： 北京市海淀区中关村东路 95 号中国科学院自动化研究所智能化大厦9层905办公室
邮政编码： 100190

部门/实验室：复杂系统管理与控制国家重点实验
研究领域

以计算机技术为主要手段，以生物医学成像为主题，主要研究内容包含三个方面：新型生物医学成像模型与方法，新型生物医学成像系统，生物医学应用。




招生信息



博导招生专业
模式识别与智能系统，研究方向：医学影像处理与分析
计算机应用技术，研究方向：生物特征识别与系统


硕导招生专业
模式识别与智能系统，研究方向：医学影像处理与分析






工作经历



工作简历
中国科学院自动化研究所，中国科学院分子影像重点实验室, 研究员，2016.10–至今
中国科学院自动化研究所，中国科学院分子影像重点实验室, 副研究员，2014.11–2016.09
中国科学院自动化研究所，中国科学院分子影像重点实验室, 助理研究员，2012.09–2014.10


部分学术任职
Frontiers in Biomedical Physics期刊编委（Frontiers Editorial Office, Switzerland），以及多个国际SCI期刊审稿人，包括Applied Physics Letters、Molecular Imaging and Biology、Nanomedicine: Nanotechnology, Biology, and Medicine、Bioorganic & Medicinal Chemistry、EJNMMI Research、Frontiers in Physics、Scientific Report等。
中国医师协会整合医学医师分会整合肿瘤学专业委员会（学组）第一届委员会，常务委员，2017.04 – 2020.04
中国研究型医院学会消化内镜分子影像学专业委员会，常务委员，2014.12 – 2019.12
泛亚消化内镜技术创新战略联盟，常务理事，2015.05 – 2018.05
中国抗癌协会整合肿瘤学分会第一届委员会，委员，2017.04至今
中华医学会核医学分会PET/MR脑功能成像专业委员会，委员，2017.09 – 2018.09
Society of Nuclear Medicine and Molecular Imaging（美国核医学与分子影像学会），会员，2013.07–至今








获奖和专利




部分学术获奖
2018年 北京市科技新星
2017年 中美核医学青年研究奖
2016年国家自然科学基金委优秀青年基金
2016年 中美核医学青年研究奖
2014年 世界分子影像大会旅行资助奖
2014年 第八届国际发明展览会金奖
2013年 中美核医学青年研究奖


部分发明专利
基于契伦科夫效应的内窥平面成像系统和方法,发明,2015,第 1 作者, 5.
近红外荧光手术成像系统及其使用方法, 发明,2018,第 2 作者,9.X.

契伦科夫光学术中成像系统及其使用方法,发明,2018,第 2 作者,7.5.
近红外二区荧光断层成像系统,发明,2018,第 3 作者,CNA.






发表论文






近年发表部分SCI期刊论文情况：
Zheng S, Zhang Z, Qu Y, Zhang X, Guo H, Shi X, Cai M, Cao C, Hu Z*, Liu H*, Tian J*. Radiopharmaceuticals and Fluorescein Sodium Mediated Triple‐Modality Molecular Imaging Allows Precise Image‐Guided Tumor Surgery. Advanced Science. 2019:**. (Highlighted as Back Cover Article)
Guo H, Yu* J, Hu Z,Yi H, Hou Y,He X*. A hybrid clustering algorithm for multiple‐source resolving in bioluminescence tomography. Journal of Biophotonics. 2018; 11(4):e.
Liu M, Zheng S, Zhang X, Guo H, Shi X, Kang X, Qu Y, Hu Z*, Tian J*. Cerenkov luminescence imaging on evaluation of early response to chemotherapy of drug-resistant gastric cancer. Nanomedicine: Nanotechnology, Biology, and Medicine. 2018; 14(1):205-213. (Highlighted as Featured Article and Cover Article)
Zhang Z, Cai M, Bao C, Hu Z*, Tian J*. Endoscopic Cerenkov luminescence imaging and image-guided tumor resection on hepatocellular carcinoma-bearing mouse models. Nanomedicine: Nanotechnology, Biology and Medicine. 2019; 17:62-70. (Highlighted as Featured Article and Cover Article)
Hu Z, Zhao M, Qu Y, Zhang X, Zhang M, Liu M, Guo H, Zhang Z, Wang J*, Yang W*, Tian J*. In vivo three-dimensional radiopharmaceutical excited fluorescence tomography. Journal of Nuclear Medicine. 2017; 58(1):169-174.
Hu Z, Chi C, Liu M, Guo H, Zhang Z, Zeng C, Ye J, Wang J, Tian J*, Yang W*, Xu W*. Nanoparticle-mediated radiopharmaceutical-excited fluorescence molecular imaging allows precise image-guided tumor-removal surgery. Nanomedicine: Nanotechnology, Biology and Medicine. 2017; 13(4):1323-1331.
Guo H, He X*, Liu M, Zhang Z, Hu Z*, Tian J*. Weight multispectral reconstruction strategy for enhanced reconstruction accuracy and stability with Cerenkov luminescence tomography. IEEE Transactions on Medical Imaging. 2017; 36(6):1337-1346.
Liu M, Guo H, Liu H, Zhang Z, Chi C, Hui H, Dong D, Hu Z*, Tian J*. In vivo pentamodal tomographic imaging for small animals. Biomedical Optics Express. 2017; 8(3):1356-1371.
Guo H, Hu Z*, He X*, Zhang X, Liu M, Zhang Z, Shi X, Zheng S, Tian J*. Non-convex sparse regularization approach framework for high multiple-source resolution in Cerenkov luminescence tomography. Optics Express, 2017, 25(23):28068-28085.
Hu Z, Qu Y, Wang K, Zhang X, Zha J, Song T, Bao C, Liu H, Wang Z, Wang J, Liu Z, Liu H*, Tian J*. In vivo nanoparticle-mediated radiopharmaceutical-excited fluorescence molecular imaging. Nature Communications. 2015; 6:7560.
Wang K, Chi C, Hu Z, Liu M, Hui H, Shang W, Peng D, Zhang S, Ye J, Liu H, Tian J*.Optical molecular imaging frontiers in oncology: the pursuit of accuracy and sensitivity. Engineering. 2015;1(3): 309-323.
Liu H, Yang X, Song T, Bao C, Shi L, Hu Z*, Wang K*, Tian J*. Multispectral hybrid Cerenkov luminescence tomography based on the finite element SPn method. Journal of Biomedical Optics. 2015; 20(8):086007.
Song T, Liu X*, Qu Y, Liu H, Bao C, Leng C, Hu Z*, Wang K*, Tian J*. A novel endoscopic Cerenkov luminescence imaging system for intraoperative surgical navigation. Molecular Imaging. 2015; 14:443-449.
Hu Z, Yang W, Liu H, Wang K, Bao C, Song T, Wang J*, Tian J*. From PET/CT to PET/MRI: advances in instrumentation and clinical applications. Molecular Pharmaceutics. 2014; 11(11):3798-3809.
Ding X, Wang K, Jie B, Luo Y, Hu Z*, Tian J. Probability method for Cerenkov luminescence tomography based on conformance error minimization. Biomedical Optics Express. 2014; 5(7):2091-2112.
Hu Z, Yang W, Ma X, Ma W, Qu X, Liang J*, Wang J*, Tian J*. Cerenkov luminescence tomography of aminopeptidase N (APN/CD13) expression in mice bearing HT1080 tumors. Molecular Imaging. 2013; 12(3):173-181.
Hu Z, Ma X, Qu X, Yang W, Liang J, Wang J*, Tian J*. Three-dimensional noninvasive monitoring iodine-131 uptake in the thyroid using a modified Cerenkov luminescence tomography approach. PLoS ONE. 2012; 7(5): e37623.
Hu Z, Chen X, Liang J*, Qu X, Chen D, Yang W, Wang J, Cao F, Tian J*. Single photon emission computed tomography-guided Cerenkov luminescence tomography. Journal of Applied Physics. 2012; 112(2):024703.
?Yang W, Qin W, Hu Z, Suo Y, Zhao R, Ma X, Ma W, Wang T, Liang J, Tian J, Wang J*. Comparison of Cerenkov luminescence imaging (CLI) and gamma camera imaging for visualization of let-7 expression in lung adenocarcinoma A549 cells. Nuclear Medicine and Biology. 2012; 39(7):948-953.
Qin C, Zhong J, Hu Z, Yang X, Tian J*. Recent advances in Cerenkov luminescence and tomography imaging. IEEE Journal of Selected Topics in Quantum Electronics. 2012; 18(3):1084-1093.
Ren N, Zhao H, Zhu S, Qu X, Liu H, Hu Z, Liang J*, Tian J*. Voxel classification methodology for rapid Monte Carlo simulation of light propagation in complex media. Chinese Optics Letters.2011; 9(4):041701-1-4.
Zhang Q, Zhao H, Chen D, Qu X, Chen X, He X, Li W, Hu Z, Liu J, Liang J*, Tian J*. Source sparsity based primal-dual interior-point method for three-dimensional bioluminescence tomography. Optical Communication. 2011; 284(24):5871-5876.
Hu Z, Liang J, Yang W, Fan W, Li C, Ma X, Chen X, Ma X, Li X, Qu X, Wang J*, Cao F*, Tian J*. Experimental Cerenkov luminescence tomography of the mouse model with SPECTimagingvalidation.OpticsExpress.2010; 18(24):24441-24450.
Liu J, Wang Y, Qu X, Li X, Ma X, Han R, Hu Z, Chen X, Sun D, Zhang R, Chen D, Chen D, Chen X, Liang J*, Cao F*, Tian J*. In vivo quantitative bioluminescence tomography using heterogeneous and homogeneous mouse models. Optical Express. 2010; 18(12):13102-13113.




部分国际会议论文发表情况：
Shi X, Zhang Z, Hu Z*, Tian J*. A doped nanoparticle mediate 18F-FDG excited fluorescence molecular imaging. The 2019 SPIE Photonics West, San Francisco, USA, February. 2-7 (oral presentation)
Hu Z, Zhang Z, Guo H, Tian J. Intraoperative Cerenkov luminescence imaging for image-guided resection of low rectal cancer on swine models. The 2018 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, Philadelphia, USA, Jun. 23-26 (oral presentation)
Hu Z, Zhang Z, Guo H, Liu M, Shi X, Tian J. Construction of a novel intraoperative Cerenkov luminescence imaging system for image-guided resection of colorectal cancer on patients. The 2017 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, Denver, USA, Jun. 10-14 (oral presentation) (2017 Young Investigator Award from the Chinese American Society of Nuclear Medicine).
Hu Z, Liu M, Guo H, Zhang Z, Tian J. Image-guided cancer surgery using a novel nanoparticle-mediated radiopharmaceutical-excited fluorescence molecular imaging. The 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, San Diego, USA, Jun. 11-15 (oral presentation) (2016 Young Investigator Award from the Chinese American Society of Nuclear Medicine).
Hu Z, Ding X, Jia X, Tian J. Comparison of Cerenkov luminescence imaging and positron emission tomography for the detection of subcutaneous breast tumor in animal models. The 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, Baltimore, USA, Jun. 6-10.
Hu Z, Tan T, Qu Y, Zhang X, Liu H, Tian J. High resolution micro-endoscopy for the diagnosis of gastric carcinoma and precancerous lesions. The 2015 World Molecular Imaging Congress, Honolulu, USA, Sept. 2-5.
Hu Z, Qu Y, Wang K, Song T, Zhang X, Liu H, Tian J. A preliminary study: radiopharmaceuticals induced fluorescence imaging in vivo. The 2014 World Molecular Imaging Congress, Seoul, Korea, Sept. 17-20 (KSMI Travel Stipend Award for the World Molecular Imaging Congress).
Hu Z, Wang K, Song T, Tian J. A new optical imaging strategy: ¹⁸F-FDG induced rare earth luminescence imaging. The 2014 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, St. Louis, USA, Jun. 7-11.
Hu Z, Qu Y, Wang K, Zhang X, Liu H, Tian J. In vivo radiopharmaceutical excitation fluorescence imaging. The 2014 IEEE nuclear science symposium and medical imaging conference, Seattle, USA, Nov. 8-15.
Hu Z, Wang K, Liu H, Mu W, Zhang Q, Du Y, Tian J. Endoscopic Cerenkov luminescence tomography of rats with gastric tumors. The 2013 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, Vancouver, Canada, Jul. 8-12 (oral presentation) (2013 Young Investigator Award for the Chinese American Society of Nuclear Medicine).
Hu Z, Liu H, Wang K, Mu W, Ding X, Tian J. Bronchoscopic Cerenkov luminescence imaging of the radioactive source with ¹⁸F-FDG. The 2013 World Molecular Imaging Congress, Georgia, USA, Sept. 18-21.
Hu Z, Yang W, Ma X, Ma W, Chen Z, Qu X, Wang J, Liang J, Tian J. Cerenkov-based optical tomography of APN/CD13 expression in the nude mice bearing HT1080 fibrosarcoma tumours. The 2012 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, Miami, USA, Jul. 9-13.
Hu Z, Zhou Y, Lin X, Yang W, Qu X, Liang J, Wang J, Tian J. Penetration depth limits of Cerenkov luminescence generation from electron-emitting radiotracer. The 2011 World Molecular Imaging Congress, San Diego, USA, Sept. 7-10.
Song T, Hu Z, Lu J, Wang K, Liu X, Tian J. In vitro and in vivo endoscopic Cerenkov luminescence imaging. The 2014 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, St. Louis, USA, Jun. 7-11 (oral presentation).
Song T, Bao C, Hu Z, Wang K, Liu X, Tian J. Endoscopic Cerenkov luminescence imaging: in vivo small animal tumor model validation. The 2015 Society of Photo-Optical Instrumentation Engineers Medical Imaging, Orlando, USA, Feb. 21-26.
Liu H, Hu Z, Wang K, Tian J. Cerenkov luminescence tomography based on preconditioning orthogonal matching pursuit. The 2015 Society of Photo-Optical Instrumentation Engineers Medical Imaging, Orlando, USA, Feb. 21-26.
Liu H, Hu Z, Wang K, Song T, Bao C, Tian J. Cerenkov luminescence tomography based on the high-order simplified spherical harmonics approximation. The 2014 World Molecular Imaging Congress, Seoul, Korea, Sept. 17-20.
Song T, Hu Z, Wang K, Liu X, Tian J. A research of small animal Cerenkov surgical navigation system. The 2014 World Molecular Imaging Congress, Seoul, Korea, Sept. 17-20.
Liu H, Hu Z, Wang K, Mu W, Tian J. An improved multispectral Cerenkov luminescence tomography for the mouse with the implanted radioactive source. The 2013 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging,Vancouver, Canada, Jul. 8-12.
Wang K, Hu Z, Liu H, Mu W, Tian J. In vivo hybrid spectral Cerenkov luminescence tomography using positron-emitting radiopharmaceutical ¹⁸F-FDG. The 2013 World Molecular Imaging Congress, Georgia, USA, Sept. 18-21.
Mu W, Liu H, Shen W, Hu Z, Wang K, Tian J. Automatic extraction of Region of Interest from the emerging Cerenkov Luminescence Endoscopy Images. The 2013 World Molecular Imaging Congress, Georgia, USA, Sept. 18-21.
Mu W, Liu H, Ding X, Song T, Hu Z, Wang K, Tian J. Uncoupled Endoscopic Cerenkov luminescence Imaging of Small Animals. The 13th Annual Conference of Chinese Biophysics Society, Nanchang, Jiangxi, 2013, Oct. 28-Nov. 1.
等国际会议邀请报告和论文及国内报告二十余次。








科研活动







作为项目负责人的部分科研项目情况：
北京市科技新星计划，“基于放射激发荧光分子成像的肿瘤早期检测新技术”，2018.01-2020.12，主持；
国家自然科学基金优秀青年科学基金项目，“分子影像”，2017.01 - 2019.12，主持；
国家重点研发计划数字诊疗装备研发重点专项，“基于核素放射激发荧光断层成像的肿瘤检测新技术”，2016.07 - 2018.12，主持；
国家自然科学基金面上项目，“放射激发荧光断层成像用于微小肿瘤诊疗一体化的研究”，2017.01 - 2019.12，主持；
中国科学院科研装备研制项目，“小动物活体多靶点多谱段光学断层分子成像系统”，2017.01-2018.12，主持；
国家自然科学基金青年项目，“基于混合谱的契伦科夫光学断层成像重建方法研究”，2014.01—2016.12，主持，已结题。









合作情况


项目协作单位
中国人民解放军总医院（301医院）
中国人民解放军总医院第三医学中心
首都医科大学附属北京天坛医院
北京协和医院
北京大学肿瘤医院
北京大学




指导学生
博士后/讲师





丁新涛 安徽师范大学 博士






博士研究生
曹财广 中国科学院自动化研究所，中国科学院分子影像重点实验室
蔡美山 中国科学院自动化研究所，中国科学院分子影像重点实验室
牟 玮 中国科学院自动化研究所，中国科学院分子影像重点实验室（已毕业）
刘海哮 中国科学院自动化研究所，中国科学院分子影像重点实验室（已毕业）
郭红波 西北大学（访问学生，已毕业）
刘沐寒 西安电子科技大学（访问学生，已毕业）
张泽宇 西安电子科技大学（访问学生）

硕士研究生
李 聪 中国科学院自动化研究所，中国科学院分子影像重点实验室
史小静 中国科学院自动化研究所，中国科学院分子影像重点实验室
宋天明 哈尔滨理工大学（访问学生，已毕业）
包成鹏 哈尔滨理工大学（访问学生，已毕业）