基本信息
胡松年男博导中国科学院微生物研究所
电子邮件： husn@im.ac.cn
通信地址： 北京市朝阳区北辰西路1号院3号
邮政编码： 100101

研究领域

招生信息
招生专业071007-遗传学
0710J3-生物信息学
0710Z1-基因组学

招生方向复杂基因组的精细结构解析
药物基因组学与精准用药指导
生物信息学工具开发与数据库构建


教育背景1991-09--1996-07中国农业大学生物化学专业 获理学博士学位
1987-09--1991-07天津商学院食品工程专业 获理学学士学位

学历
学位

工作经历
工作简历2019-08~现在,中国科学院微生物研究所,研究员 博士生导师
2003-02~2019-07,中国科学院北京基因组研究所,研究员 博士生导师
2002-02~2008-09,浙江大学沃森基因组科学研究院,教授 硕士生导师
1999-08~2003-02,中国科学院遗传与发育研究所人类基因组中心,总工程师
1998-08~1999-07,美国西雅图华盛顿大学基因组中心,访问
1996-09~1998-07,中国医学科学院基础医学研究所,助理研究员
1991-09~1996-07,中国农业大学,生物化学专业 获理学博士学位
1987-09~1991-07,天津商学院,食品工程专业 获理学学士学位

社会兼职

教授课程基因组信息系统与实践
基因组学分析技术与原理
基因组学技术与原理
基因组学
基因组学前沿
基因组学实用技术讲座


专利与奖励
奖励信息（1） 河北省科学技术进步三等奖, 三等奖, 省级, 2015
（2） 唐山市科技进步二等奖, 二等奖, 市地级, 2015
（3） 国务院特殊津贴_, 国家级, 2014
（4） 中国科学院朱李月华优秀教师奖, , 院级, 2008
（5） 利用EST信息资源大规模克隆家蚕功能基因 浙江省科学技术一等奖, 一等奖, 省级, 2007
（6） 中国科学院优秀教师奖, , 院级, 2006
（7） 中国杂交水稻基因组计划 中国科学院杰出科技成就集体奖, , 院级, 2003
（8） 中国杂交水稻基因组计划 香港求是科技基金求是杰出科技成就集体奖, , 其他, 2002

专利成果

出版信息
发表论文（1）Evolview v3: a webserver for visualization, annotation, and management of phylogenetic trees,Nucleic Acids Res,2019-07,第11作者
（2）Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in Panax ginseng.,BMC Genomics,2019-05,第11作者
（3）The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize,Mol Plant,2019-05,第11作者
（4）RGAAT: A Reference-based Genome Assembly and Annotation Tool for New Genomes and Upgrade of Known Genomes,Genomics Proteomics Bioinformatics,2018-10,第11作者
（5）REDO: RNA Editing Detection in Plant Organelles Based on Variant Calling Results,J Comput Biol.,2018,第11作者
（6）Identification of a G2-like transcription factor, OsPHL3, functions as a negative regulator of flowering in rice by co-expression and reverse genetic analysis.,BMC Plant Biol.,2018,第11作者
（7）Tung Tree (Vernicia fordii, Hemsl.) Genome and Transcriptome Sequencing Reveals Co-Ordinate Up-Regulation of Fatty Acid β-Oxidation and Triacylglycerol Biosynthesis Pathways During Eleostearic Acid Accumulation in Seeds.,Plant Cell Physiol.,2018,第11作者
（8）Analysis of gut microbiota diversity and auxiliary diagnosis as a biomarker in patients with schizophrenia: A cross-sectional study.,Schizophr Res.,2018,第11作者
（9）Rice Expression Database (RED): An integrated RNA-Seq-derived gene expression database for rice,Journal of Genetics and Genomics,2017,第12作者
（10）Genetic Alterations in Esophageal Tissues From Squamous Dysplasia to Carcinoma,Gastroenterology,2017,第12作者
（11）DRDB: An Online Date Palm Genomic Resource Database,Front Plant Sci.,2017,第11作者
（12）CYP2A6 Polymorphisms Associate with Outcomes of S-1 Plus Oxaliplatin Chemotherapy in Chinese Gastric Cancer Patients,Genomics, Proteomics & Bioinformatics,2017,第11作者
（13）ISVASE: identification of sequence variant associated with splicing event using RNA-seq data,BMC Bioinformatics,2017,第11作者
（14）A meta-analysis of the association of CKM gene rs** polymorphism with sport performance,Biology of Sport,2017,第11作者
（15）REDO: RNA Editing Detection in Plant Organelles Based on Variant Calling Results,Journal of Computational Biology,2017,第11作者
（16）DRDB: An Online Date Palm Genomic Resource Database,Frontiers in Plant Science,2017,第11作者
（17）MVP: a microbe-phage interaction database,Nucleic Acids Research,2017,第4作者
（18）Comparative genome analysis of programmed DNA elimination in nematodes,Genome Research,2017,第12作者
（19）De novo Transcriptome Analysis Reveals Distinct Defense Mechanisms by Young and Mature Leaves of Hevea brasiliensis (Para Rubber Tree),Scientific Reports,2016,第11作者
（20）Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host,Nat Commun,2016,第11作者
（21）Conserved intramolecular interactions maintain myosin interacting-heads motifs explaining tarantula muscle super-relaxed state structural basis,Journal of molecular biology,2016,第11作者
（22）Information Commons for Rice (IC4R),Nucleic Acids Research,2016,第11作者
（23）Identification and analysis of house-keeping and tissue-specific genes based on RNA-seq data sets across 15 mouse tissues,Gene,2016,第11作者
（24）De novo sequencing and transcriptome analysis of Pleurotus eryngii subsp. tuoliensis (Bailinggu) mycelia in response to cold stimulation,Moleculars,2016,第11作者
（25）Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees,Nucleic Acids Research,2016,第11作者
（26）Identification and analysis of mouse non-coding RNA using transcriptome data,Science China. Life Sciences,2016,第11作者
（27）The rubber tree genome reveals new insights into rubber production and species adaptation,Nature Plants,2016,第11作者
（28）De novo sequencing and transcriptome analysis of Pleurotus eryngii subsp. tuoliensis (Bailinggu) mycelia in response to cold stimulation,Moleculars,2016,第11作者
（29）Metatranscriptomic analyses of plant cell wall polysaccharide degradation by microorganisms in cow rumen,Applied and Ennvironmental Microbiology,2015,第11作者
（30）Integrated analysis of gene expression and microRNA regulation in three leukemia-related lymphoblastic cell lines,Gene,2015,第11作者
（31）De novo transcriptome analysis of Medicago falcata reveals novel insights about the mechanisms underlying abiotic stress-responsive pathway,BMC Genomics,2015,第11作者
（32）Genome-wide mapping of 5-hydroxymethylcytosine in three rice cultivars reveals its preferential localization in transcriptionally silent transposable element genes,Journal of Experimental Botany,2015,第11作者
（33）An integrated RNA-Seq and network study reveals a complex regulation process of rice embryo during seed germination,Biochemical and Biophysical Research Communications,2015,第11作者
（34）Profiling microRNA expression during multi-staged date palm (Phoenix dactylifera L.) fruit development,Genomics,2015,第11作者
（35）Evaluation of the optimal dosage of S-1 in adjuvant SOX chemotherapy for gastric cancer,Oncology Letters,2015,第11作者
（36）Transcriptomic study of the red palm weevil Rhynchophorus ferrugineus embryogenesis,Insect Science,2015,第11作者
（37）Whole transcriptome RNA-seq analysis: tumorigenesis and metastasis of melanoma,Gene,2014,第11作者
（38）De novo characterization of the spleen transcriptome of the large yellow croaker (Pseudosciaena crocea) and analysis of the immune relevant genes and pathways involved in the antiviral response,PLoS One,2014,第11作者
（39）XELIRI compared with FOLFIRI as a second-line treatment in patients with metastatic colorectal cancer,Oncology Letters,2014,第11作者
（40）Transcriptional profiling of biomass degradation-related genes during Trichoderma reesei growth on different carbon sources,Journal of Biotechnology,2014,第11作者
（41）Transgenic rice plants overexpressing BBTI4 confer partial but broad-spectrum bacterial blight resistance,Journal of Plant Biology,2013,第11作者
（42）Dynamic transcriptomes of human myeloid leukemia cells,Genomics,2013,第11作者
（43）Genome sequence of the date palm Phoenix dactylifera L,Nat Commun.,2013,第1作者
（44）The Complete Mitochondrial Genome of Gossypium hirsutum and Evolutionary Analysis of Higher Plant Mitochondrial Genomes,PLos One,2013,第11作者
（45）Insight into the specific virulence related genes and toxin-antitoxin virulent pathogenicity islands in swine streptococcosis pathogen Streptococcus equi ssp zooepidemicus strain ATCC35246,BMC Genomics,2013,第11作者
（46）Digital Gene Expression Tag Profiling Analysis of the Gene Expression Patterns Regulating the Early Stage of Mouse Spermatogenesis,PLoS One,2013,第11作者
（47）Large-scale collection and annotation of gene models for date palm (Phoenix dactylifera, L.),Plant Molecular Biology,2012,第11作者
（48）Comparative transcriptome analysis of transporters, phytohormone and lipid metabolism pathways in response to arsenic stress in rice (Oryza sativa L.) ,New Phytologist ,2012,第11作者
（49）High-throughput sequencing-based gene profiling on multi-staged fruit development of date palm (Phoenix dactylifera, L.),Plant Molecular Biology,2012,第11作者
（50）Evolutional and functional analysis of a serine protease in Spodoptera litura,Archives of Insect Biochemistry and Physiology,2012,第11作者
（51）Comparative analysis of the genomes of two field isolates of the rice blast fungus Magnaporthe oryzae,PLoS Genetics,2012,第4作者
（52）Pyrosequencing the Bemisia tabaci transcriptome reveals a highly diverse bacterial community and a robust system for insecticide resistance,PLoS One,2012,第11作者
（53）A large-scale gene discovery for the red palm weevil Rhynchophorus ferrugineus (Coleoptera: Curculionidae),Insect Science,2012,第11作者
（54）Thousands of novel transcripts identified in mouse cerebrum, testis, and ES cells based on ribo-minus RNA sequencing,Frontiers in Genetics,2012,第11作者
（55）Replication-associated mutational pressure (RMP) governs strand-biased compositional asymmetry (SCA) and gene organization in animal mitochondrial genomes,Current Genomics,2012,第11作者
（56）Complete genome sequence of the metabolically versatile halophilic archaeon Haloferax mediterranei, a Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) producer,Journal of Bacteriology,2012,第11作者
（57）Molecular identification of Diphyllobothrium latum and a brief review of diphyllobothriosis in China,Acta Parasitologica,2012,第11作者
（58）A complete sequence and transcriptomic analysis of date palm (Phoenix dactylifera L.) mitochondrial genome,PLoS One,2012,第11作者
（59）Transcriptome comparison between honey bee queen- and worker-destined larvae,Insect Biochemistry and Molecular Biology,2012,第11作者
（60）EvolView, an online tool for visualizing, annotating and managing phylogenetic trees,Nucleic Acids Research,2012,第11作者
（61）Genomic analysis of the multi-drug resistant Acinetobacter baumannii strain MDR-ZJ06 widely spread in China,Antimicrobial Agents and Chemotherapy. ,2011,第11作者
（62）wapRNA: a web-based application for the processing of RNA sequences,Bioinformatics. ,2011,第11作者
（63）Hydroxyurea-induced global transcriptional suppression in mouse ES cells,Carcinogenesis,2010,第11作者
（64）A comparison between ribo-minus RNA-sequencing and polyA-selected RNA-sequencing,Genomics,2010,第11作者
（65）Transcriptome and expression profiling analysis revealed changes of multiple signaling pathways involved in immunity in the large yellow croaker during Aeromonas hydrophila infection.,BMC genomics,2010,第11作者
（66）
发表著作（ 1 ） 基因组数据分析手册,handbook of genomic data analysis,浙江大学出版社,2003-05,第1作者
（ 2 ） 基因表达序列标签（EST）数据,handbook of expressed sequence tag (est) data analysis,浙江大学出版社,2005-05,第1作者
（ 3 ） 基因组学概论（第二版）,Introduction to Genomics (Second edition),科学出版社,2016-01,第2作者
（ 4 ） 转录组学与精准医学,Transcriptomics and Precision Medicine,上海交通大学,2017-12,第2作者


科研活动
科研项目（ 1 ） 广东潮汕食管癌发病风险预测的分子基础研究, 参与,省级,2012-05--2015-12
（ 2 ） 应用组学策略选育茶薪菇新品种与人工栽培技术研究, 主持,部委级,2012-01--2015-12
（ 3 ） 基于第二代测序技术及比较转录组学的人参皂苷合成途径及调控网络研究, 主持,国家级,2012-01--2016-08
（ 4 ） 水稻粒型分子模块系统解析, 主持,部委级,2013-08--2017-12
（ 5 ） 2016YFC**, 主持,国家级,2016-07--2018-12
（ 6 ） 精准医学大数据处理和利用的标准化技术体系建设, 参与,国家级,2016-07--2019-12
（ 7 ） 转录组纵深信息挖掘, 主持,国家级,2006-12--2011-08
（ 8 ） 基于小鼠多组织和细胞链特异性RNA-seq数据的Antisense RNA 分析及数据库构建, 主持,国家级,2013-01--2016-12

参与会议

合作情况
项目协作单位

指导学生