基本信息
郭明全男博导中国科学院武汉植物园
电子邮件： guomq@wbgcas.cn
通信地址： 湖北武汉武昌磨山中国科学院武汉植物园66号信箱
邮政编码： 430074
部门/实验室：博导
研究领域

招生信息
招生专业071001-植物学

招生方向药用植物化学
植物功能代谢组学
生物活性筛选


教育背景1998-09--2004-06中国科学院长春应用化学研究所研究生、博士

学历
学位

工作经历
工作简历2007-10~2012-07,美国南加州大学,研究助理
2006-03~2007-09,美国加州大学柏克莱国家实验室,博士后
2004-07~2006-02,美国国家卫生研究院(NIH),博士后
1998-09~2004-06,中国科学院长春应用化学研究所,研究生、博士

社会兼职2017-01-01-今,专业杂志编委Phytochemical Analysis, 杂志编委
2015-01-01-今,植物科学学报, 杂志编委
2011-10-01-2012-04-30,专业杂志客座编辑 Current Analytical Chemistry, 客座编辑
2010-09-01-今,专业杂志编委 The Scientific World Journal, 编委
2008-03-01-今,专业杂志编委 Asian Journal of Chemistry, 编委


教授课程

专利与奖励
奖励信息（1） 吉林省科学技术进步一等奖, 一等奖, 省级, 2006
（2） 中国科学院宝洁优秀博士奖, 一等奖, 院级, 2004

专利成果（ 1 ） 刺五加叶的质量检测方法, 2002, 第 4 作者, 专利号: **.X
（ 2 ） 一种十数樟提取物的制备方法和应用, 2016, 第 1 作者, 专利号: ZL 1.0
（ 3 ） 一种载药纳米银粒子的制备方法及其应用, 2016, 第 1 作者, 专利号: 7.3
（ 4 ） 一种快速筛选天然产物中拓扑异构酶I抑制剂的方法, 2017, 第 1 作者, 专利号: ZL0.5


出版信息
发表论文（1）Screening for anti-proliferative and anti-inflammatory components from Rhamnus davurica Pall. using bio-affinity ultrafiltration with multiple drug targets,Analytical and Bioanalytical Chemistry,2018,第11作者
（2）Ce ll Cyc le Arre s t a nd Apoptos is in HT-29 Ce lls Induc e d by Dic hlorome tha ne Fra c tion From Todda lia a s ia tic a (L.) Lam.,Frontiers in Pharmacology,2018,第11作者
（3）Current advances in screening for bioactive components from medicinal plants by affinity ultrafiltration mass spectrometry,Phytochemical Analysis,2018,第11作者
（4）Comparative study on alkaloids and their anti-proliferative activities from three Zanthoxylum species,BMC Complementary and Alternative Medicine,2017,第11作者
（5）Comparative Analysis of Saponins from Different Phytolaccaceae Species and Their Antiproliferative Activities,Molecules,2017,第11作者
（6）Rapid screening α-glucosidase inhibitors from Gymnema sylvestre by affinity ultrafiltration-HPLC- MS,Frontiers in Pharmacology,2017,第11作者
（7）Mass spectrometry (MS)-based translational proteomics for biomarker discovery and application in colorectal cancer,Proteomics Clin Appl.,2016,第11作者
（8）Components and Anti-Hep G2 Activity Comparison of Lycopodium Alkaloids from Four Geographic Origins,Evidence-Based Complementary and Alternative Medicine,2016,第11作者
（9）Analysis of volatile compounds responsible for kiwifruit aroma by desiccated headspace gas chromatography-mass spectrometry,J. Chromatogr. A.,2016,第11作者
（10）Antiproliferative activity against HT-29 and Hep G2 cells of Amaryllidaceae alkaloids from Lycoris radiata targeted on topoisomerase I,Scientific reports,2016,第11作者
（11）Current Advances in the Metabolomics Study on Lotus Seeds,Frontiers in Plant Science,2016,第11作者
（12）CBP-dependent Wnt/β-catenin signaling is crucial in regulation of MDR1 transcription,Current Cancer Drug Targets,2015,第1作者
（13）Comparative Analysis of Amaryllidaceae Alkaloids from Three Lycoris Species,Molecules,2015,第11作者
（14）Phenolic Profiling of Duchesnea indica Combining Macroporous Resin Chromatography (MRC) with HPLC-ESI-MS/MS and ESI-IT-MS,Molecules,2015,第11作者
（15）Chemical proteomic strategies for the discovery and development of anticancer drugs,proteomics,2014,第11作者
（16）Integration of phosphoproteomic, chemical, and biological strategies for the functional analysis of targeted protein phosphorylation,Proteomics,2013,第1作者
（17）Targeted functional analysis of p300 activator in Wnt/beta-catenin signaling pathway using phosphoproteomic and biochemical approaches.,Journal of Proteomics,2012,第11作者
（18）Liquid Chromatography and Mass Spectrometry (LC-MS) Based Strategies for Quantitative Phosphoproteomics,Current Analytical Chemistry,2012,第11作者
（19）Functional phosphosite screening for targeted protein-protein interactions by combining phosphoproteomics strategies and mammalian two-hybrid assays,Molecular Biosystems,2011,第1作者
（20）Functional analysis of novel phosphorylation sites of CREB-binding protein using mass spectrometry and mammalian two-hybrid assay,Proteomics,2011,第11作者
（21）Conformation changes of Akt1 activation probed by amide H/D exchange and nano-electrospray ionization mass spectrometry,Rapid Commun. Mass Spectrom.,2009,第1作者
（22）Analysis of Saponins from Leaves of Aralia Elata by Liquid Chromatography and Tandem Mass Spectrometry,Analytical Sciences,2009,第1作者
（23）Neuronal Specific Increase in Phosphatidylserine by Docosahexaenoic Acid (DHA),Journal Molecular Neuroscience,2007,第1作者
（24）Characterization of Triterpenoid Saponin Mixture in Crude Extracts from Leaves of Acanthopanax Senticosus Harms by Saponin Structural Correlations and Mass Spectrometry,Anal. Chim. Acta,2006,第1作者
（25）Characterization of Non-covalent Inclusion Complexes of Rutin with Cyclodextrins by Electrospray Tandem Mass Spectrometry,J. Mass Spectrom,2004,第1作者
（26）Study on the Non-covalent Complexes between Oleanolic acid and Cyclodextrins Using Electrospray Tandem Mass Spectrometry,J. Mass Spectrom,2003,第1作者

发表著作

科研活动
科研项目（ 1 ） 药物化学与功能代谢组学, 主持,部委级,2012-08--2015-08
（ 2 ） 天然药用植物保健品, 主持,研究所（学校）,2013-05--2017-05
（ 3 ） 非洲天然产物开发利用, 主持,部委级,2016-01--2020-12
（ 4 ） 药用植物化学生物学, 主持,部委级,2015-01--2017-12
（ 5 ） 基于功能蛋白组学和超滤质谱技术研究石蒜抗肝癌的作用机制与化学物质基础, 主持,国家级,2017-01--2020-12
（ 6 ） 非洲特有药用植物开发利用合作研究, 主持,省级,2017-08--2019-12

参与会议（1）Analysis of Endocannabinoids in Plasma Combining Magnetic Dispersive Micro-extraction (MDME) with UPLC-MS第六届亚洲太平洋质谱国际会议丁俊2015-07-18
（2）蛇莓中多酚类化学成分的研究中国植物学会第十三届全国药用植物及植物药学术研讨会朱洺志2015-07-12
（3）Identification of plant flavonoids and their non-covalent complexes by ESI-MSMingquan Guo2012-10-05
（4）Functional Analysis of Site-specific Phosphorylation of p300/CBPMingquan Guo; Zanxian Xia; Hong Ma2012-05-20
（5）Phosphorylation of CBP in the β-catenin interacting N-terminusMingquan Guo, Zanxian Xia, Hong Ma2011-06-05
（6）Phosphorylation of p300 in the β-catenin interacting N-terminusMQ Guo, ZX Xia, H Ma. 2009-05-31


合作情况
项目协作单位

指导学生