基本信息
滕兆乾男博导中国科学院动物研究所
电子邮件： tengzq@ioz.ac.cn
通信地址： 北京市海淀区北四环西路25-1号303室
邮政编码： 100190

研究领域

招生信息
招生专业071008-发育生物学
071006-神经生物学

招生方向再生医学
干细胞与脑损伤修复
神经再生


教育背景2002-09--2005-07中国科学院动物研究所博士
1999-09--2002-07山东师范大学生命科学学院硕士

学历
学位

工作经历
工作简历2014-09~现在,中国科学院动物研究所,研究员
2014-01~2014-08,Johns Hopkins University School of Medicine,Research Associate
2011-03~2013-12,Louisiana State University School of Medicine,博士后
2008-08~2011-02,University of New Mexico School of Medicine,博士后
2005-09~2008-03,中国农业大学农学与生物技术学院,博士后
2002-09~2005-07,中国科学院动物研究所,博士
1999-09~2002-07,山东师范大学生命科学学院,硕士

社会兼职2018-03-12-今,Guest Associate Editor for Frontiers in Genetics,
2015-12-31-今,Member of International Society for Stem Cell Research, Member
2009-10-01-今,美国神经学会会员,


教授课程再生医学导论


专利与奖励
奖励信息
专利成果（ 1 ） 一种多能干细胞诱导产生小胶质细胞的方法及试剂盒, 2019, 第 1 作者, 专利号: CNA


出版信息
发表论文（1）Regulatory Networks between Polycomb Complexes and Non-coding RNAs in Central Nervous System,Journal of Molecular Cell Biology,2019-10,第4作者
（2）MiR-137 Deficiency Causes Anxiety-Like Behaviors in Mice,Frontiers in Molecular Neuroscience,2019-10,第11作者
（3）Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus,Stem Cell Reports,2019-09,第7作者
（4）GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells,Stem Cell Research,2019-07,第11作者
（5）Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a,Nature Neuroscience,2018-11,第11作者
（6）Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System,The Neuroscientist,2018,第3作者
（7）Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration,Cell Death and Differentiation,2018,第10作者
（8）Commentary: Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus,Frontiers in Molecular Neuroscience,2018,第11作者
（9）A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs,Stem Cell Reports,2018,第7作者
（10）miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirds,eLIFE,2018,第7作者
（11）The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice,Front. Mol. Neurosci.,2017,第11作者
（12）MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells,Stem Cell Reports,2017,第11作者
（13）Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury,Neural Plasticity,2016,第2作者
（14）Inhibition of monoacylglycerol lipase prevents chronic traumatic encephalopathy-like neuropathology in a mouse model of repetitive mild closed head injury,J Cereb Blood Flow Metab,2014,第2作者
（15）Synaptic and Cognitive Improvements by Inhibition of 2-AG Metabolism Are through Upregulation of MicroRNA-188-3p in a Mouse Model of Alzheimers Disease,J Neurosci,2014,第3作者
（16）Δ9-THC-Caused Synaptic and Memory Impairments Are Mediated through COX-2 Signaling,Cell,2013,第1作者
（17）An Epigenetic Feedback Regulatory Loop Involving MicroRNA-195 and MBD1 Governs Neural Stem Cell Differentiation,PLoS ONE,2013,第2作者
（18）RNA binding protein FXR2 regulates proliferation and differentiation of adult hippocampal neural stem cells by repressing Noggin expression,Neuron,2011,第4作者
（19）Epigenetic Regulation of miR-184 by MBD1 Governs Neural Stem Cell Proliferation and Differentiation,Cell Stem Cell,2010,第1作者

发表著作

科研活动
科研项目（ 1 ） 引进人才科研启动费, 主持,市地级,2014-09--2018-12
（ 2 ） 多重性脑创伤后miRNAs对海马神经发生与胶质细胞发生的调控机制, 主持,国家级,2016-01--2019-12
（ 3 ） 中国科学院“****”, 主持,研究所（学校）,2015-01--2018-12
（ 4 ） '干细胞与脑损伤修复, 主持,市地级,2015-01--2017-12
（ 5 ） 免疫球蛋白E受体在脑损伤修复中的功能与分子调控机制研究, 主持,省级,2018-01--2020-12
（ 6 ） 脑创伤大脑皮层的神经再生机制与修复, 主持,部委级,2018-08--2019-12
（ 7 ） 疾病相关神经前体细胞的分子标记物鉴定与质控标准, 主持,国家级,2018-07--2022-12

参与会议（1）“脑创伤大脑皮层的神经再生机制与修复”2019年度报告中国科学院战略性先导科技专项“器官重建与制造”“神经再生”重点公关方向研讨会2019-11-27
（2）GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells中国干细胞第九届年会刘聪，代尚昆，杜洪震2019-09-19
（3）脑创伤大脑皮层的神经再生机制与修复中国科学院战略性先导科技专项“器官重建与制造”研讨会2019-07-31
（4）MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells2017-08-18
（5）Histone H3 Lysine 27 demethylase UTX regulates postnatal hippocampal neurogenesis2016-06-22
（6）Synaptic and cognitive improvements by inhibition of monoacylglycerol lipase are through upregulation of the miRNA targeting BACE1 in Alzheimer’s diseaseChen C., Zhang J., Teng Z.-Q.2013-11-09
（7）Mecp2-regulated miR-137 governs neuronal maturationTENG Z-Q., SMRT R. D., SZULWACH K. E., PFEIFFER R. L., LI X., GUO W., PATHANIA M., LUO Y., WILSON M. C., BORDEY A., JIN P., ZHAO X.2010-11-13
（8）Mbd1 and mir-184 molecular network governs neural stem cell proliferation and differentiationLIU C., TENG Z.-Q., FLITCROFT C., SZULWACH K., JIN P., ZHAO X.2010-11-13
（9）MicroRNA miR-137 regulates neuronal maturation by targeting ubiquitin ligase Mind Bomb-1TENG Z-Q., SMRT R. D., SZULWACH K., LUO Y., WILSON M. C., BORDEY A., JIN P., ZHAO X.2010-06-27


合作情况
项目协作单位

指导学生