基本信息
向俊锋男硕导中国科学院化学研究所
电子邮件： jfxiang@iccas.ac.cn
通信地址： 北京市海淀区中关村北一街2号
邮政编码：

研究领域

招生信息
招生专业070304-物理化学

招生方向波谱学


教育背景1997-09--2002-07中国科学院理化技术研究所博士
1992-09--1997-07北京大学化学学院学士

学历
学位

工作经历
工作简历2016-01~现在,中国科学院化学研究所,分析测试中心副主任
2005-04~现在,中国科学院化学研究所,核磁组长
2005-04~现在,中国科学院化学研究所,副研究员
2002-07~2005-03,日本关西学院大学,博士后
1997-09~2002-07,中国科学院理化技术研究所,博士
1992-09~1997-07,北京大学化学学院,学士

社会兼职2012-01-01-今,北京理化分析测试技术学会波谱专业委员会, 副理事长
2012-01-01-今,北京理化分析测试技术学会, 常务理事
2012-01-01-今,中国分析测试协会, 专家组成员


教授课程有机结构分析
核磁共振原理及应用


专利与奖励
奖励信息（1） 院所两级公共技术服务中心优秀集体, 院级, 2018
（2） 北京市科学技术奖二等奖：“基于谱学技术和组学原理的中药物质基础研究的技术体系构建及应用”, 二等奖, 省级, 2015
（3） 中国分析测试协会科学技术奖二等奖：“基于纳米超分子可控组装的检测探针设计及临床应用”, 二等奖, 其他, 2014
（4） 中国药学会科学技术奖三等奖：“靶向G-四链体的药物先导物发现、研究及应用”, 三等奖, 其他, 2012
（5） “中关村物质科学大型仪器区域中心”2011年度仪器使用共享之星, 院级, 2011
（6） 中国分析测试协会科学技术奖一等奖：“基于生物靶分子识别的天然抗肿瘤分子筛选鉴定一体化技术”, 一等奖, 其他, 2009
（7） 中国分析测试协会科学技术奖三等奖：“抗肿瘤药物分子与生物大分子相互作用的谱学研究”, 三等奖, 其他, 2007

专利成果

出版信息
发表论文（1）Superstretchable Dynamic Polymer Networks,Adv. Mater,2019-11,第10作者
（2）Low‐Temperature Reverse Water–Gas Shift Process and Transformation of Renewable Carbon Resources to Value‐Added Chemicals,ChemSusChem,2019-10,第4作者
（3）An Injectable Strong Hydrogel for Bone Reconstruction,Adv. Healthcare Mater,2019-09,第4作者
（4）Ultra-tough injectable cytocompatible hydrogel for 3D cell culture and cartilage repair,Journal of Materials Chemistry B,2018,第4作者
（5）From CO2 to 4H?Quinolizin-4-ones: A One-Pot Multicomponent Approach via Ag2O/Cs2CO3 Orthogonal Tandem Catalysis,The Journal of Organic Chemistry,2018,第2作者
（6）Ethyl-substitutive Thioflavin T as a highly-specific fluorescence probe for detecting G-quadruplex structure,Scientific Reports,2018,第5作者
（7）Ultrasensitive and high specific detection of non-small-cell lung cancer cells in human serum and clinical pleural effusion by aptamer-based fluorescence spectroscopy,Talanla,2018,第3作者
（8）MCl4n- (AuCl4-, PtCl42-, or PdCl42-) anion extraction from NanMCl4 in water using a tetraimidazolium macrocyclic receptor,Tetrahedron Letters,2018,第2作者
（9）Novel fluorescent cationic benzothiazole dye tha tresponds to G-quadruplex aptamer as a novel K+ sensor,Analyst,2017,第3作者
（10）Discrete 1 : 1 complexes and higher order assemblies formed from aminobenzene sulphonate anions and a tetraimidazolium ‘‘molecular box’’,Chem Comm,2017,第4作者
（11）Ionic liquid accelerates the crystallization of Zr-based metal–organic frameworks,Nature Comm,2017,第3作者
（12）Selective Utilization of the Methoxy Group in Lignin to Produce Acetic Acid,Angew. Chem. Int. Ed,2017,第6作者
（13）Dual effects of dimethylsulfoxide on cellulose solvating ability of 1-allyl-3-methylimidazolium chloride,Cellulose,2016,第11作者
（14）Characterizing the adsorption of poly(vinyl alcohol) on colloidal silica with aggregation-induced emission fluorophore,Langmuir,2016,第4作者
（15）Pure shift proton NMR spectroscopy and its applications,Chin. J. Magn. Reson.,2016,第11作者
（16）Stabilizing G-quadruplex DNA by methylazacalix n pyridine through shape-complementary interaction,Bioorg. Med. Chem. Lett.,2016,第11作者
（17）Selective recognition of specific G-quadruplex vs. duplex DNA by a phenanthroline derivative,Int. J. Biol. Macromol.,2015,第2作者
（18）A comparative study for recognizing G-quadruplexes using dimeric cyanine dyes with different sizes of aromatic substituents,Anal. Methods,2015,第3作者
（19）Targeting of parallel c-myc G-quadruplex by dimeric cyanine dye supramolecular assembly: dependence on the linker length,Analyst,2015,第11作者
（20）Multicomponent self-assembled metal-organic 3 rotaxanes,J. Am. Chem. Soc.,2015,第11作者
（21）Directly lighting up RNA G-quadruplexes from test tubes to living human cells,Nucleic Acids Res.,2015,第3作者
（22）Controllable cy3-MTC-dye aggregates and its applications served as a chemosensor,Dyes Pigment.,2015,第2作者
（23）Novel DNA catalysts based on G-quadruplex for organic synthesis,Adv. Synth. Catal.,2015,第2作者
（24）Pyridostatins selectively recognize two different forms of the human telomeric G-quadruplex structures and their anti-tumor activities in vitro,Tetrahedron,2015,第4作者
（25）2,6-Pyridodicarboxamide-bridged triptycene molecular transmission devices: converting rotation to rocking vibration,J. Org. Chem.,2015,第3作者
（26）A colorimetric lead (II) ions sensor based on selective recognition of G-quadruplexes by a clip-like cyanine dye.,Talanta,2015,第4作者
（27）i-Motif-modulated fluorescence detection of silver(I) with an ultrahigh specificity,Anal. Chim. Acta,2015,第3作者
（28）Cation-triggered switchable asymmetric catalysis with chiral aza-crownphos,Angew. Chem.-Int. Edit.,2015,第4作者
（29）Stepwise motion in a multivalent [2](3)catenane,J. Am. Chem. Soc.,2015,第11作者
（30）Non-flat bisbenzylisoquinoline alkaloid fangchinoline as a class of potent G-quadruplex stabilizer with anti-cancer activity,Chin. J. Chem.,2015,第2作者
（31）Copper-catalyzed intramolecular C-C bond cleavage to construct 2-substituted quinazolinones,Eur. J. Org. Chem.,2015,第4作者
（32）Cu(II)-catalyzed domino reaction of 2-halobenzamide and arylmethanamine to construct 2-aryl quinazolinone,Chin. Chem. Lett.,2015,第4作者
（33）G-quadruplex induced chirality of methylazacalix 6 pyridine via unprecedented binding stoichiometry: en route to multiplex controlled molecular switch,Sci Rep,2015,第3作者
（34）Aromatic sulfonate anion-induced pseudorotaxanes: environmentally benign synthesis, selectivity, and structural characterization,Chem. Commun.,2015,第11作者
（35）Tuneable dynamics of a scandium nitride cluster inside an Ih-C80 cage,Dalton Trans.,2015,第3作者
（36）Dissolution mechanism of cellulose in N,N-dimethylacetamide/lithium chloride: revisiting through molecular interactions,J. Phys. Chem. B,2015,第3作者
（37）Naryl-substituted anthranilamides with intramolecular hydrogen bonds,Tetrahedron,2014,第11作者
（38）Facile synthesis of N-iodoacetyl-N'-biotinyl-3,6-dioxaoctane-1,8-diamine,Chin. J. Syn. Chem.,2014,第2作者
（39）A colorimetric and fluorometric dual-modal supramolecular chemosensor and its application for HSA detection,Analyst,2014,第2作者
（40）A colorimetric temperature sensor of a cyanine dye supramolecule and its application in reversible switch,Appl. Phys. Lett.,2014,第2作者
（41）A newly identified G-quadruplex as a potential target regulating Bcl-2 expression.,Biochim. Biophys. Acta-Gen. Subj.,2014,第2作者
（42）Construction of DNA logic gates utilizing a H+/Ag+ induced i-motif structure,Chem. Commun.,2014,第3作者
（43）Tristable [n]rotaxanes: from molecular shuttle to molecular cable car,Chem. Sci.,2014,第2作者
（44）Intermolecular interactions and 3D structure in cellulose-NaOH-urea aqueous system,J. Phys. Chem. B,2014,第3作者
（45）Highly sensitive chemical-vapor sensor based on thin-film organic field-effect transistors with benzothiadiazole-fused-tetrathiafulvalene,Adv. Funct. Mater.,2013,第4作者
（46）Quantification of the Na+/K+ ratio based on the different response of a newly identified G-quadruplex to Na+ and K+,Chem. Commun.,2013,第2作者
（47）The effect of polyhydroxylated alkaloids on maltase-glucoamylase,PLoS One,2013,第2作者
（48）G4LDB: a database for discovering and studying G-quadruplex ligands,Nucleic Acids Res.,2013,第2作者
（49）Novel dual-functional regulation of a chair-like antiparallel G-quadruplex inducing assembly-disassembly of a cyanine dye,Phys. Chem. Chem. Phys.,2013,第3作者
（50）Roles of flanking sequences in the binding between unimolecular parallel-stranded G-quadruplexes and ligands,Chin. Sci. Bull.,2013,第3作者
（51）A novel signal-amplified strategy based on assembly reactivation for highly specific and sensitive detection of chair-like antiparallel G-quadruplex.,Analyst,2013,第3作者
（52）A dual-site simultaneous binding mode in the interaction between parallel-stranded G-quadruplex d(TGGGGT)4 and cyanine dye 2,2'-diethyl-9-methyl-,Nucleic Acids Res.,2013,第3作者
（53）Recognize three different human telomeric G-quadruplex conformations by quinacrine,Analyst,2012,第2作者
（54）Visual detection of potassium by a cyanine dye supramolecular aggregate responsive to G-quadruplex motif transition,Analyst,2012,第2作者
（55）Screening alpha-glucosidase inhibitors from mulberry extracts via DOSY and relaxation-edited NNR,Talanta,2012,第2作者
（56）Searching drug-like anti-cancer compound(s) based on G-quadruplex ligands,Curr. Pharm. Design,2012,第2作者
（57）NMR identification of anti-influenza lead compound targeting at PAC subunit of H5N1 polymerase,Chin. Chem. Lett.,2012,第3作者
（58）Screen anti-influenza lead compounds that target the PAC subunit of H5N1 viral RNA polymerase,PLoS One,2012,第3作者
（59）Interaction between PEO-PPO-PEO copolymers and a hexapeptide in aqueous solutions,Langmuir,2012,第3作者
（60）The interaction of telomeric DNA and c-myc22 G-quadruplex with 11 natural alkaloids,Nucl. Acid Ther.,2012,第3作者
（61）Complexation between triptycene-based macrotricyclic host and pi-extended viologens: formation of supramolecular poly 3 pseudorotaxanes,Chem. Commun.,2012,第3作者
（62）Regulating the conformation of methylazacalix[6]pyridine by oligonucleotide BCL-2 2345 and its recognition of hydroxymethylpiperazinofullerene.,J. Phys. Chem. B,2012,第11作者
（63）Mingyue Tian, Studies of the interactions between three protoberberine alkaloids and Bcl-2 by fluorescence spectroscopy,Acta Chim. Sin.,2011,第4作者
（64）Constructing transferrin receptor targeted drug delivery system by using doxorubicin hydrochloride and vanadocene dichloride,Bioorg. Med. Chem. Lett.,2011,第2作者
（65）Self-assembly of a new C60 compound with a L-glutamid-derived lipid unit: formation of organogels and hierarchically structured spherical particles,Soft Matter,2011,第4作者
（66）An important functional group, benzo 1,3 dioxole, of alkaloids induces the formation of the human telomeric DNA G-quadruplex,Chin. Sci. Bull.,2011,第11作者
（67）alide-guided oligo(aryl-triazole-amide)s foldamers: receptors for multiple halide ions,Chem.-Eur. j.,2011,第2作者
（68）Controllable assembly and cycling conversion of various supramolecular aggregates of a cyanine dye,Appl. Phys. Lett.,2011,第2作者
（69）A stabilizing and denaturing dual-effect for natural polyamines interacting with G-quadruplexes depending on concentration,Biochimie,2011,第2作者
（70）, A low-bandgap conjugated polymer based on squaraine with strong two-photon absorption,Macromolecules,2011,第3作者
（71）Fishing potential antitumor agents from natural plant extracts pool by dialysis and G-quadruplex recognition,Talanta,2011,第2作者
（72）Screening anti-influenza agents that target avian influenza polymerase protein PAC from plant extracts based on NMR methods,Chem. Lett.,2011,第3作者
（73）Interaction between reduced glutathione and PEO-PPO-PEO copolymers in aqueous solutions: studied by 1H NMR and spin-lattice relaxation,J. Phys. Chem. B,2011,第4作者
（74）A new tetrathiafulvalene-phenoxynaphthacenequinone dyad: switching on the intramolecular electron-transfer with UV light irradiation and metal ion coordination,Chem. Commun.,2011,第4作者
（75）Effects of loops and nucleotides in G-quadruplexes on their interaction with an azacalixarene, methylazacalix[6]pyridine,J. Phys. Chem. B,2011,第3作者
（76）Synthesis and Aggregation Behavior of a Hexameric Quaternary Ammonium Surfactant,Langmuir,2011,第3作者
（77）Direct screening of G-quadruplex ligands from Kalopanax septemlobus (Thunb.) Koidz extract by high performance liquid chromatography,J. Chromatogr. A,2011,第4作者

发表著作

科研活动
科研项目（ 1 ） 金属富勒烯纳米肿瘤无创诊疗系统研制, 参与,国家级,2016-01--2018-12

参与会议

合作情况
项目协作单位

指导学生