基本信息
肖吉昌男博导中国科学院上海有机化学研究所
电子邮件： jchxiao@mail.sioc.ac.cn
通信地址： 上海市零陵路345号
邮政编码： 200032

研究领域

招生信息
招生专业070303-有机化学

招生方向氟化学
稀土萃取与稀土化学
氟盐化学


教育背景2000-08--中科院上海有机所博士

学历 -- 研究生

学位 -- 博士


工作经历
工作简历2005-08~现在,中科院上海有机所,研究员

社会兼职

教授课程有机氟化学


专利与奖励
奖励信息
专利成果（ 1 ） 一种具有推拉电子结构的咪唑离子盐、制备方法及其用途, 发明, 2010, 第 1 作者, 专利号: CN
（ 2 ） 一种高密度离子液体及其制备方法, 发明, 2011, 第 1 作者, 专利号: ZL9.6
（ 3 ） 一类含氟苯并噻唑磺酰类化合物、制备及应用, 发明, 2011, 第 1 作者, 专利号: ZL6.8
（ 4 ） 三氟甲基芳基锍盐在金属引发下对杂环化合物的三氟甲基化, 发明, 2013, 第 1 作者, 专利号: ZL4.4
（ 5 ） 一种用于制备熔盐的熔炼炉, 实用新型, 2014, 第 1 作者, 专利号: ZL9.6
（ 6 ） 一种用于制备氟化物熔盐的反应罐, 实用新型, 2015, 第 1 作者, 专利号: ZL2.X
（ 7 ） 一种气体分布器及包括其的鼓泡反应器, 实用新型, 2016, 第 1 作者, 专利号: ZL5.9
（ 8 ） 一种高纯度的氟化物熔盐及其制备方法, 发明, 2016, 第 1 作者, 专利号: ZL9.4
（ 9 ） 一种萃取体系、萃取方法及反萃取方法, 发明, 2016, 第 1 作者, 专利号: ZL8.7


出版信息
发表论文（1）One-Step Synthesis of High-purity Li2BeF4 Molten Salt,J. Fluorine Chem. 2016, 181, 30-35,2016,通讯作者
（2）O-difluoromethylation of 1,3-diones with S-difluoromethyl sulfonium salt,RSC Adv. 2016, 6, 35705-35708,2016,通讯作者
（3）Nucleophilic arylation with tetraarylphosphonium salts,Nat. Commun. 2016, 7: 10337 doi: 10.1038/ncomms10337,2016,通讯作者
（4）Cu-catalyzed C-H trifluoromethylation of 3-arylprop-1-ynes for the selective construction of allenic Csp2-CF3 and propargyl Csp3-CF3 bonds,Org. Lett. 2016, 18, 1000-1003,2016,通讯作者
（5）DBU-Promoted Trifluoromethylation of Aryl Iodides with Difluoromethyltriphenylphosphonium Bromide,Chin. J. Chem. 2016, 34, 481-484,2016,通讯作者
（6）Prediction of solubility properties from transfer energies for acidic phosphorus-containing Rare-Earth extractants using Implicit Solvation Model,Solvent Extr. Ion Exch. 2016, 34, 347-354,2016,通讯作者
（7）pKa Prediction for Acidic Phosphorus-Containing Compounds Using Multiple Linear Regression with Computational Descriptors,J. Comput. Chem. 2016, 37, 1668-1671,2016,通讯作者
（8）A Trifluoromethylcarbene Source,Org. Lett. 2016, 18, 2471-2474,2016,通讯作者
（9）α,β-Substituent effect of dialkylphosphinic acids on lanthanide extraction,RSC Adv. 2016, 6, 56004-56008,2016,通讯作者
（10）Hydroperfluoroalkylation of electron-deficient olefins with perfluoroalkyl iodides promoted by Zinc / viologen,RSC Adv. 2016, 6, 60080-60083,2016,通讯作者
（11）Direct Nucleophilic Difluoromethylation of Carbonyl Compounds,Org. Lett. 2016, 18, 3206-3209,2016,通讯作者
（12）FLiNaK熔盐中微量氧的测定,Determination of trace oxygen in FLiNaK molten salt,中国无机分析化学，2015, 5(1), 45-48,2015,通讯作者
（13）1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)-Promoted Decomposition of Difluorocarbene and the Subsequent Trifluoromethylation,Org. Lett. 2015, 17, 532-535,2015,通讯作者
（14）Difluoromethylation and gem-difluorocyclopropenation with difluorocarbene generated by decarboxylation,Chem. Commun. 2015, 51, 8805-8808,2015,通讯作者
（15）An overview of reductive trifluoromethylation reactions using electrophilic '+CF3' reagents,Tetrahedron 2015, 71, 7949-7976,2015,通讯作者
（16）Diastereoselective Johnson-Corey-Chaykovsky trifluoroethylidenation,Chem. Commun. 2015, 51, 13127-13130,2015,通讯作者
（17）Recent Advances in C-H Trifluoromethylthiolation and Trifluoromethoxylation Reactions,Curr. Org. Chem. 2015, 19, 1541-1553,2015,通讯作者
（18）One-pot synthesis of gem-difluorostyrenes from benzyl bromide via olefination of phosphonium ylide with difluorocarbene,J. Fluorine Chem. 2015, 179, 116-120,2015,通讯作者
（19）Difluorocarbene-Derived Trifluoromethylthiolation and [18F]Trifluoromethylthiolation of Aliphatic Electrophiles,Angew. Chem. Int. Ed. 2015, 54, 13236-13240,2015,通讯作者
（20）Cross-Coupling between difluorocarbene and carbene-derived in-termediates generated from diazocompounds for the synthesis of gem-difluoroolefins,Org. Lett. 2015, 17, 6150-6153,2015,通讯作者
（21）Microwave-assisted synthesis of dialkylphosphinic acids and a structure–reactivity study in Rare Earth metal extraction,RSC Adv. 2015, 5, 104258-104262,2015,通讯作者
（22）Difluoromethylation and Trifluoromethylation Reagents Derived from Tetrafluoroethane β-Sultone: Synthesis, Reactivity and Applications,Coord. Chem. Rev. 2014, 261, 28-72,2014,通讯作者
（23）Rh-Catalyzed Allylic C-F Bond Activation: The Stereosynthesis of Trisubstituted Monofluoroalkenes and A Mechanism Study,Org. Biomol. Chem. 2014, 12, 581-588,2014,通讯作者
（24）Boron-trihalide-promoted Regioselective Ring-opening Reactions of gem-Difluorocyclopropyl Ketones,Chem. Commun. 2014, 50, 1077-1079,2014,通讯作者
（25）Decarboxylative Julia–Kocienski gem-difluoroolefination of 2-Pyridinyl sulfonyl-difluoroacetate,Eur. J. Org. Chem. 2014, 928-932,2014,通讯作者
（26）Copper-mediated Trifluoromethylation of Propargyl Acetates Leading to Trifluoromethyl-allenes,Org. Biomol. Chem. 2014, 12, 2903–2906,2014,通讯作者
（27）FLiNaK熔盐的制备,Preparation of FLiNaK molten salt,核技术，2014, 37, 050604-1-5,2014,通讯作者
（28）Wittig gem-Difluoroolefination of Aldehydes with Difluoromethyltriphenylphosphonium Bromide,J. Fluorine Chem. 2014, 163, 38-41,2014,通讯作者
（29）盐析剂存在下稀土含量的准确测定,Accurate Measurement of Rare Earth in the Presence of Salting-Out Agent—NaCl,中国稀土学报 2014, 32, 370-376,2014,通讯作者
（30）Cu-promoted Oxidative Trifluoromethylation of Terminal Alkynes with Difluoromethylene Phosphobetaine,Chin. J. Chem. 2014, 32, 689-693,2014,通讯作者
（31）Recent advances in asymmetric fluorination and fluoroalkylation reactions via organocatalysis,Tetrahedron Lett. 2014, 55, 6147-6155,2014,通讯作者
（32）Copper-catalyzed Tandem Trifluoromethylation/ Cyclization of Internal Alkynes,Org. Chem. Front. 2014, 1, 1280-1284,2014,通讯作者
（33）Stereoselective Synthesis of α-Trifluoromethyl Enones by Au(I)/Cu(I)-Cocatalyzed Tandem 1,3-Acyloxy Migration/Trifluoromethylation of Propargyl Acetates,Eur. J. Org. Chem. 2014, 7948-7954,2014,通讯作者
（34）Direct N-gem-difluorocyclopropylation of nitro-heterocycles by utilizing gem-difluorocyclopropyl Tosylate,Chin. Chem. Lett. 2014, 25, 24-28,2014,通讯作者
（35）Copper-mediated trifluoromethylation of terminal alkynes by S-(trifluoromethyl)diarylsulfonium salt,Chin. J. Chem. 2013, 31, 915-920,2013,通讯作者
（36）Synthesis and decarboxylative Wittig reaction of difluoromethylene phosphobetaine,Chem. Commun. 2013, 49, 7513-7515,2013,通讯作者
（37）A novel reaction of gem-difluorocyclopropyl ketones with nitriles leading to 2-fluoropyrroles,Chem. Commun. 2013, 49, 9833-9835,2013,通讯作者
（38）Conversion between Difluorocarbene and Difluoromethylene Ylide,Chem. Eur. J. 2013, 19, 15261-15266,2013,通讯作者
（39）氯乙酸缓冲体系在稀土测定中的应用研究,Research on buffer solution of chloroacetic acid in rare earth detection,中国稀土学报 2013, 31, 636-640,2013,通讯作者
（40）Copper-catalyzed Trifluoromethylation of Alkenes with Electrophilic Trifluoromethylating Reagent,Beilstein J. Org. Chem. 2013, 9, 2635-2640,2013,通讯作者
（41）Bi-Functional Fluoroalkylation Reagents: An introduction to Halo-substituted 3-Oxa-Perfluoroalkanesulfonyl Fluorides,Tetrahedron 2013, 69, 10955-10989,2013,通讯作者
（42）Efficient Synthesis of 1-Alkyl-3-methylimidazolium Fluorides and Possibility of the Existence of Hydrogen Bonding Between Fluoride Anion and C(sp3)–H,J. Fluorine Chem. 2012, 133, 160-162.,2012,通讯作者
（43）Electrophilic Fluoroalkylation of Ni(II) N-Confused Porphyrins with Fluoroalkylarylsulfonium Salts,J. Org. Chem. 2012, 77, 3604-3608.,2012,通讯作者
（44）Progress in fluoroalkylation of organic compounds via sulfinatodehalogenation initiation system,Chem. Soc. Rev. 2012, 41, 4536-4559.,2012,通讯作者
（45）The asymmetric synthesis of CF3- or -CF2-substituted tetrahydroquinolines by employing a chiral phosphoric acid as catalyst,Chem. Commun. 2012, 48, 7738-7740.,2012,通讯作者
（46）聚苯乙烯-co-聚(2,3,4,5,6-五氟苯乙烯)共聚物：合成及其多孔薄膜的制备,Polystyrene-co-poly(2,3,4,5,6-pentafluorostyrene) Copolymers: Synthesis and Fabrication of Their Porous Films,化学学报，2012, 70, 1125-1130,2012,通讯作者
（47）Generation of the CF3 radical from trifluoromethylsulfonium triflate and,Chem. Commun., 2011, 47, 6632–6634,2011,通讯作者
（48）Copper-Mediated Trifluoromethylation of Heteroaromatic Compounds by Trifluoromethyl Sulfonium Salts,Angew. Chem. Int. Ed. 2011, 50, 1896-1900,2011,通讯作者
（49）Monofluorovinyl Tosylate: A Useful Building Block for the Synthesis of Terminal Vinyl Monofluorides via Suzuki-Miyaura Coupling,Org. Lett., 2011, 13, 560–563,2011,通讯作者
（50）Thermal rearrangement of substituted difluoro(methylene)cyclopropane,J. Fluorine Chem. 2011, 132, 63-67,2011,通讯作者
（51）N-Heterocyclic Carbene Catalyzed Reaction of Alkynyl Aldehydes with 1,3-Ketoesters or 1,3-Diketones,Adv. Synth. Catal. 2010, 352, 2455-2458,2010,通讯作者
（52）Synthesis and Physicochemical Properties of Bis(fluoroalkanesulfonyl)imide-based Ionic Liquids,Eur. J. Inorg. Chem. 2010, 3419-3422,2010,通讯作者
（53）Electrophilic Reaction of Ag(III) N-Confused Porphyrin with Alcohols,J. Org. Chem. 2010, 75, 3511-3514,2010,通讯作者
（54）Determination of pKa Values of Fluoroalkanesulfonamides and Investigation of Their Nucleophilicity,J. Fluorine Chem. 2010, 131, 761-766,2010,通讯作者
（55）New Electrophilic Bromodifluoromethylation and Pentafluoroethylation Reagents,Synlett 2010, 1089-1092,2010,通讯作者
（56）One-pot synthesis of arylfluoroalkylsulfoxides and study of their anomalous 19F NMR behavior,J. Fluorine Chem. 2010, 131, 433-438,2010,通讯作者
（57）Enantioselective aldol reaction of cyclic ketones with aryl aldehydes catalyzed by a cyclohexanediamine derived salt in the presence of water,Green Chem. 2009, 11, 1750-1753,2009,通讯作者
（58）Unexpected Reactions of Push-Pull N-Heterocyclic Carbene Derived from N-(4-methoxyphenyl)-N-(4-nitrophenyl)-imidazolium Chloride,Synlett 2009, 2305-2308,2009,通讯作者
（59）Reaction of difluorocarbene with propargyl esters and efficient synthesis of difluorocyclopropyl ketones,Tetrahedron 2009, 65, 6320-6324,2009,通讯作者
（60）A mild hydrodehalogenation of fluoroalkyl halides,J. Fluorine Chem. 2009, 130, 671-673,2009,通讯作者
（61）The Oxidation of Ni(II) N-Confused Porphyrins (NCPs) with Azo Radical Initiators and an Unexpected Intramolecular Nucleophilic Substitution Reaction via a Proposed Ni(III) NCP Intermediate,Chem. Commun. 2009, 3732-3734,2009,通讯作者
（62）A novel pyrrolidinium ionic liquid with 1,1,2,2-tetrafluoro-2-(1,1,2,2- tetrafluoroethoxy)ethanesulfonate anion as a recyclable reaction medium and efficient catalyst for Friedel-Crafts alkylations of indoles with nitroalkenes,J. Fluorine Chem. 2009, 130, 394-398,2009,通讯作者
（63）Synthesis and Reactions of the First Fluoroalkylated Ni(II) N-Confused Porphyrins,Chem. Commun. 2008, 5435-5437,2008,通讯作者
（64）Ring-Opening Reactions of Difluoro(methylene)cyclopropanes with Halogens and Amines,J. Org. Chem. 2008, 73, 8598-8600,2008,通讯作者
（65）Novel low-melting salts with donor-acceptor substituents as targets for second-order nonlinear optical applications,Chem. Commun. 2008, 5016-5018,2008,通讯作者
（66）1,3-Dipolar Cycloaddition of Difluoro(methylene)cyclopropanes with Nitrones: Efficient synthesis of 3,3-Difluorinated Tetrahydropyridinols,Synlett 2008, 1989-1992,2008,通讯作者
（67）Reactions of HMPA with hexafluorobenzene, pentafluorochlorobenzene and pentafluorophenol,J. Fluorine Chem. 2008, 129, 424-428,2008,通讯作者
（68）Highly regio- and stereoselective Diels-Alder cycloaddition of difluoro(methylene)cyclopropanes,Eur. J. Org. Chem. 2008, 1101-1106,2008,通讯作者

发表著作

科研活动
科研项目（ 1 ） 高张力有机小分子——二氟(亚甲基)环丙烷的合成与反应研究, 主持,国家级,2010-01--2012-12
（ 2 ） 氟烷基锍盐的制备与反应研究, 主持,国家级,2012-01--2015-12
（ 3 ） 单氟烯烃的合成与反应, 主持,国家级,2015-01--2018-12
（ 4 ） 高效稀土萃取剂的分子设计、合成与性能, 主持,国家级,2012-01--2016-08

参与会议（1）Conversion Between Difluorocarbene And Difluoromethylene Ylide第21届国际氟化学会议2015-08-23
（2）Synthesis and Reaction of Some Fluorine-containing Phosphonium Salts 第十七届欧洲氟化学会议2013-07-21


合作情况
项目协作单位

指导学生已指导学生
辜伟鹏**
杭晓春**
蔡吉**
蒋华卫**
郝菲**
林锦鸿**
张成潘**
朱志强**
李强**
张禾**
于静**
季云龙**
姜延华**
郑剑**
邓祖勇**
现指导学生
于蛟**
罗佳佳**
邓晓云**
段亚亚**
张维**
张敏**
陈佳**
张唯**