姓名：周雪林 性别：男 职称：副教授 招生院所：基础医学院 招生类型：科学学位(硕) 招生专业：药理学(硕) 研究方向名称：天然药物药理学与药代动力学 电子信箱：zhouxuelin@ccmu.edu.cn


社会任职
1. 中国药理学会分析药理专业委员会青年委员会委员
2. 北京药理学会药物代谢专业委员会委员
个人简历
1. 200109-200507:中国药科大学生命科学与技术学院 本科生
2. 200509-200807:中国药科大学生命科学与技术学院 硕士研究生
3. 200908-201209:香港中文大学生物医学学院 博士研究生
4. 201209-201609:香港中文大学中医中药研究所 科研助理
5. 201610-201803:中国人民解放军第三〇二医院药学部 助理研究员
6. 201804-:首都医科大学基础医学院 副教授
重要学术论文
1. Ma Y, Wu Y, Xia Z, Li J, Li X, Xu P, Zhou X*, Xue M*.Anti-Hypoxic Molecular Mechanisms of Rhodiola crenulata Extract in Zebrafish as Revealed by Metabonomics. Frontiers in Pharmacology. 2019,10:1356.SCI
2. Yang Q#, Zhou X#, Li J, Ma Y, Lu L, Xiong J, Xu P, Li Y, Chen Y, Gu W, Xue M, Jin Z*, Li X*.Sub-Acute Oral Toxicity of a Novel Derivative of Agomelatine in Rats in a Sex-Dependent Manner. Frontiers in Pharmacology. 2019,10:242.SCI
3. Zhou X, Li H, Shi Z, Gao S, Wei S, Li K, Wang J, Li J, Wang R, Gong M, Zhao Y*, Xiao X.Inhibition activity of a traditional Chinese herbal formula HuangLian-Jie-Du-Tang and its major components found in its plasma profle on neuraminidase-1. Scientific Reports. 2017,7:15549.SCI
4. Ma JY#, Zhou X#, Fu J, He CY, Feng R, Huang M, Shou JW, Zhao ZX, Li XY, Zhang L, Chen YC, Wang Y.In vivo metabolite profiling of a purified ellagitannin isolated from Polygonum capitatum in rats. Molecules. 2016,21(9):1110.SCI
5. Zhou X, Lam WP, Tang HC, Koon CM, Cheng L, Lau CB, Liang W*, Leung PC*.Effects of Gegen (Puerariae lobatae Radix) water extract on improving detrusor overactivity in spontaneously hypertensive rats. Phytomedicine. 2016,23(6):672-678.SCI
6. Zhou X, Cheung CM, Yang JM, Or PM, Lee WY*, Yeung JH.Danshen (Salvia miltiorrhiza) water extract inhibits paracetamol-induced toxicity in primary rat hepatocytes via inhibiting CYP2E1 activity and oxidative stress. Journal of Pharmacy and Pharmacology. 2015,67(7):980-989.SCI
7. Zhou X*, Wang Y, Lee WY, Or PM, Wan DC, Kwan YW*, Yeung JH.Miltirone is a dual inhibitor of p-glycoprotein and cell proliferation in doxorubicin-resistant HepG2 cells. Journal of Natural Products. 2015,78(9):2266-2275.SCI
8. Ma JY#, Zhou X#, Fu J#, Hu T, Or PM, Feng R, He CY, Chen WJ, Zhang X, Chen Y*, Wang Y*, Yeung JH.Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in vitro. Chemico-Biological Interactions. 2014,220:33-40.SCI
9. Feng R#, Zhou X#, Tan XS#, Or PM, Hu T, Fu J, Ma JY, Huang M, He CY, Shi JG, Che CT, Yeung JH*, Wang Y*.In vitro identification of cytochrome P450 isoforms responsible for the metabolism of 1-hydroxyl-2, 3, 5-trimethoxy-xanthone purified from Halenia elliptica D. Don. Chemico-Biological Interactions. 2014,210:12-19.SCI
10. Zhou X, Siu WS, Fung CH, Cheng L, Wong CW, Zhang C, Liu CL, Kwok HF, Lau CP, Wat E, Lau CB, Leung PC, Ko CH*, Hung LK*.Pro-angiogenic effects of Carthami Flos whole extract in human microvascular endothelial cells in vitro and in zebrafish in vivo. Phytomedicine. 2014,21(11):1256-1263.SCI
11. Zhou X*, Wang Y, Hu T, Or PM, Wong J, Kwan YW*, Wan DC, Hoi PM, Lai PB, Yeung JH.Enzyme kinetic and molecular docking studies for the inhibitions of miltirone on major human cytochrome P450 isozymes. Phytomedicine. 2013,20(3-4):367-374.SCI
12. Zhou X, Wang Y, Or PM, Wan DC, Kwan YW, Yeung JH*.Molecular docking and enzyme kinetic studies of dihydrotanshinone on metabolism of a model CYP2D6 probe substrate in human liver microsomes. Phytomedicine. 2012,19(7):648-657.SCI
13. Feng R#, Zhou X#, Or PM, Ma JY, Tan XS, Fu J, Ma C, Shi JG, Che CT, Wang Y*, Yeung JH*.Enzyme kinetic and molecular docking studies on the metabolic interactions of 1-hydroxy-2, 3, 5-trimethoxy-xanthone, isolated from Halenia elliptica D. Don, with model probe substrates of human cytochrome P450 enzymes. Phytomedicine. 2012,19(12):1125-1133.SCI
14. Zhou X#, Chan SW#, Tseng HL#, Deng Y, Hoi PM, Choi PS, Or PM, Yang JM, Lam FF, Lee SM, Leung GP, Kong SK, Ho HP, Kwan YW*, Yeung JH*.Danshensu is the major coefficient for antioxidant and vasorelaxation effects in Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions. Phytomedicine. 2012,19(14):1263-1269.SCI
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重要奖项