姓名：陈彪 性别：男 职称：教授 招生院所：附属宣武医院 招生类型：科学与专业学位(博) 科学与专业学位(硕) 招生专业：神经病学(博) 神经病学(硕) 研究方向名称：神经变性病的基础和临床研究 电子信箱：pbchan90@gmail.com


社会任职
1. 首都医科大学教授，博士生导师
2. 国家人类基因组北方研究中心副主任
3. 北京市老年保健及疾病防治中心副主任
4. 中国医师协会老年医学分会总干事
5. 亚大老年学和老年医学学会 秘书长
6. 教育部“神经变性病重点实验室”副主任
7. 北京脑重大研究院帕金森病研究所所长
8. 帕金森病研究北京市重点实验室主任
9. 国家老年疾病临床医学研究中心主任
个人简历
1. 197809-198308:湖南医学院医疗系 本科学习
2. 198509-199006:中山医科大学 神经病学博士研究生
3. 199008-199209:美国帕金森病研究所 博士后
4. 199206-199406:美国帕金森病研究所 研究员
5. 199407-200011:美国帕金森病研究所 高级研究员，课题主持人
6. 199502-200011:美国帕金森病研究所 分子遗传实验室主任
7. 199607-:中山医科大学 客座教授
8. 199810-:首都医科大学宣武医院 主任医师，教授
重要学术论文
1. Ji S, Wang C, Qiao H, Gu Z, Gan-Or Z, Fon EA, Chan P*.Decreased Penetrance of Parkinson's Disease in Elderly Carriers of Glucocerebrosidase Gene L444P/R Mutations: A Community-Based 10-Year Longitudinal Study. Mov Disord. 2020,【未填写卷（期）】:【未填写起止页码】.SCI
2. Chhetri JK, Han C, Dan X, Ma L, Chan P*.Motoric Cognitive Risk Syndrome in a Chinese Older Adult Population: Prevalence and Associated Factors. J Am Med Dir Assoc. 2020,21(1):136-137.SCI
3. Mi TM, Garg S, Ba F, Liu AP, Wu T, Gao LL, Dan XJ, Chan P*, McKeown MJ.High-frequency rTMS over the supplementary motor area improves freezing of gait in Parkinson's disease: a randomized controlled trial.. Parkinsonism Relat Disord. 2019,68:85-90.SCI
4. Xu X, Chen J, Chen M, Gu Z, Ji S, Liu S, Chan P*.Postural Tremor Is Associated with Gait and Balance Impairments in Community-Dwelling Older People. J Am Geriatr Soc. 2019,67(4):799-803.SCI
5. Gao LL, Zhang JR, Chan P, Wu T*.Levodopa Effect on Basal Ganglia Motor Circuit in Parkinson's Disease. CNS Neurosci Ther. 2017,23(1):76-86.SCI
6. Liu SY, Chan P, Stoessl AJ.The underlying mechanism of prodromal PD: insights from the parasympathetic nervous system and the olfactory system. Transl Neurodegener. 2017,【未填写卷（期）】:【未填写起止页码】.
7. Mi TM, Mei SS, Liang PP, Gao LL, Li KC, Wu T, Chan P*.Altered resting-state brain activity in Parkinson's disease patients with freezing of gait.. Sci Rep.. 2017,7(1):16711.SCI
8. Chhetri JK, Zheng Z, Xu X, Ma C, Chan P*.The prevalence and incidence of frailty in Pre-diabetic and diabetic community-dwelling older population: results from Beijing longitudinal study of aging II (BLSA-II). BMC Geriatr. 2017,17(1):47.SCI
9. Yue F, Zeng S, Tang R, Tao G, Chan P*.MPTP Induces Systemic Parkinsonism in Middle-Aged Cynomolgus Monkeys: Clinical Evolution and Outcomes. Neurosci Bull. 2017,33(1):17-27.SCI
10. 曹明，陈彪*.吸烟与帕金森病嗅觉障碍. 中国现代神经疾病杂志. 2017,02:101-104.核心期刊
11. Xiu S, Zheng Z, Guan S, Zhang J, Ma J, Chan P.Serum uric acid and impaired cognitive function in community-dwelling elderly in Beijing. Neurosci Lett. 2017,637:182-187.SCI
12. 毛薇,许二赫,张慧,陈彪*.早发帕金森病临床特征、多巴转运体PET显像及基因突变分析. 中国神经免疫学和神经病学杂志. 2017,01:2-6.核心期刊
13. Zheng Z, Guan S, Ding H, Wang Z, Zhang J, Zhao J, Ma J, Chan P*.Prevalence and Incidence of Frailty in Community-Dwelling Older People: Beijing Longitudinal Study of Aging II. J Am Geriatr Soc. 2016,64(6):1281-1286.SCI
14. Zhang H, Gu Z, Sun L, Cao M, Li D, Ma J, Chan P*.Clinical Manifestation of Parkinson's Disease in Association with Rapid Eye Movement Sleep Behavior Disorder Onset. Eur Neurol. 2016,76(3-4):154-160.SCI
15. 刘疏影,陈彪*.帕金森病流行现状. 中国现代神经疾病杂志. 2016,02:98-101.核心期刊
16. 畅怡,聂秀红,魏兵,肖汉,张连国,李艳,詹淑琴,陈彪.具有梦境展现行为的阻塞性睡眠呼吸暂停综合征的多导睡眠监测特点. 首都医科大学学报. 2016,03:376-381.核心期刊
17. Dan X, Wang C, Zhang J, Gu Z, Zhou Y, Ma J, Chan P*.Association between common genetic risk variants and depression in Parkinson's disease: A dPD study in Chinese. Parkinsonism Relat Disord. 2016,33:122-126.SCI
18. Wu T*, Zhang J, Hallett M, Feng T, Hou Y, Chan P.Neural correlates underlying micrographia in Parkinson's disease. Brain. 2016,139(Pt 1):144-160.SCI
19. Dan X, King BR, Doyon J, Chan P. .Motor Sequence Learning and Consolidation in Unilateral De Novo Patients with Parkinson's Disease.. PLoS One.. 2015,Jul29;10(7):e**:【未填写起止页码】.SCI
20. Wang C, Xu Y, Feng X, Ma J, Xie S, Zhang Y, Tang BS, Chan P.Linkage analysis and whole-exome sequencing exclude extra mutations responsible for theparkinsonian phenotype of spinocerebellar ataxia-2. Neurobiol Aging. 2015,Jan;36(1):545:e1-7..SCI
21. Xu S, Chan P.. Interaction between Neuromelanin and Alpha-Synuclein in Parkinson's Disease. Biomolecules.. 2015,Jun 5;5(2)::1122-42.SCI
22. Jean Woo*, Zheng Zheng#, Jason Leung, Piu Chan*.Prevalence of frailty and contributory factors in three Chinese populations with different socioeconomic and healthcare characteristics. BMC Geriatrics. 2015,15:163:【未填写起止页码】.SCI
23. Yu S, Chan P.Role of α-synuclein in neurodegeneration: implications for the pathogenesis of Parkinson’s disease.. Essays Biochem. 2014,56:125-135.SCI
24. Dan X, Wang C, Ma J, Feng X, Wang T, Zheng Z, Chan P..MAPT IVS1+124 C>G modifies risk of LRRK2 G2385R for Parkinson's disease in Chinese individuals.. Neurobiol Aging. 2014,35(7):1780.e7-1780.e10..SCI
25. Wang C, Cai Y, Gu Z, Ma J, Zheng Z, Tang BS, Xu Y, Zhou Y, Feng T, Wang T, Chen SD, Chan P..Clinical profiles of Parkinson's disease associated with common leucine-rich repeat kinase 2 and glucocerebrosidase genetic variants in Chinese individuals.. Neurobiol Aging. 2014,35(3):725.e1-6.SCI
26. Wu T, Liu J, Hallett M, Zheng Z, Chan P..Cerebellum and Integration of Neural Networks in Dual-Task Processing. NeuroImage. 2013,15(65):466-75.SCI
27. Liu J, Zhou Y, Wang C, Wang T, Zheng Z, Chan P.Brain-derived neurotrophic factor (BDNF) genetic polymorphism greatly increases risk of leucine-rich repeat kinase 2 (LRRK2) for Parkinson's disease. Parkinsonism Relat Disord. 2012,18(2):140-3.SCI
28. Wang C, Cai Y, Zheng Z, Tang B, Xu Y, Wang T, Ma J, Chen S, Langston JW, Tanner C, Chan P;.Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants.. Parkinsonism Relat Disord. 2012,18::958-963.SCI
29. Xuan Q, Xu SL, Lu DH, Yu S, Zhou M, Uéda K, Cui YQ, Zhang BY, Chan P*.Increase expression of α-synuclein in aged human brain associated with neuromelanin accumulation.. J Neural Transm. 2011,Nov;118(11):1575-83.SCI
30. Liu N, Yue F, Tang WP, Chan P.An Objective Measurement of Locomotion Behavior for Hemiparkinsonian Cynomolgus Monkeys. J Neurosci Methods. 2009,183(2):188-194.SCI
31. Zhang JL, Yang JF, Chan P.No Association between Polymorphism of Serotonin Transporter Gene and Depression in Parkinson’s disease in Chinese.. Neurosci Lett. 2009,455(3):155-158.SCI
32. Cai Y, Liu S, Sothern RB, Li N, Guan Y, Chan P.Epigenetic analysis of mPer1 promoter in peripheral tissues. Biological Rhythm Research. 2009,40(6):445-453.SCI
33. Wu T, Long X, Zang Y, Wang L, Hallett M, Li K, Chan P.Regional homogeneity changes in patients with Parkinson’s disease. Hum Brain Mapp. 2009,30(5):1502-1510.SCI
34. Wu T, Wang L, Chen Y, Zhao C, Li K, Chan P.Changes of functional connectivity of the motor network in the resting state in Parkinson's disease. Neurosci Lett. 2009,460:6-10.SCI
35. Qin Z, Zhang L, Sun F, Liu H, Fang X, Chan P.Chinese Parkinson Study Group. Depressive symptoms impacting on health-related quality of life in early Parkinson's disease: results from Chinese L-dopa exposed cohort. Clin Neurol Neurosurg. 2009,111(9):733-737.SCI
36. 王坚，李尧华，郑晓立，张燕莉，李昕，于顺，何欣，陈彪.弱阳离子交换纳米磁珠介导的帕金森病血清蛋白质组学的初步研究. 中华神经科杂志. 2009,42（2）:98-101.
37. Fan W, Ding H, Ma J, Chan P.Impulse Control Disorders in Parkinson’s Disease in a Chinese Population. Neurosci Lett. 2009,465(1):6-9.SCI
38. Yang JF, Wu T, Li JY, Li YJ, Zhang YL, Chan P.DYT1 mutations in early onset primary torsion dystonia and Parkinson disease patients in Chinese populations. Neurosci Lett. 2009,450(2): 117-121.SCI
39. 马敬红，邹海强，胡国华，王枫，孙菲，陈彪.起病年龄对帕金森病运动并发症的影响. 中华神经科杂志. 2009,42（1）:50-52.
40. 秦朝晖，陈彪，张丽燕，樊文辉，孙菲，方向华，孟琛，Caroline Tanner.早期帕金森病患者健康相关生活质量. 中华神经科杂志. 2009,42（8）:514-519.
41. 左晓虹，蔡彦宁，李宁，刘姝，张燕莉，陈彪.小鼠纹状体时钟基因表达的生后发育. 中华行为医学与脑科学杂志. 2009,18（5）:385-387.
42. Cai Y, Liu S, Li N, Xu S, Zhang Y, Chan P.Postnatal ontogenesis of molecular clock in mouse striatum. Brain Res. 2009,1264:33-38.SCI
43. Wu T, Chan P, Hallett M. Modifications of the interactions in the motor network when a movement becomes automatic. J Physiology. 2008,586（17）:4295-4304.SCI
44. 吴晓莉，陈彪*.磁共振波谱在帕金森病中的应用. 脑与神经疾病杂志. 2008,16（4）:531-533.
45. Yu S, Zhao T, Guo M, Fang HX, Ma JX, Ding AS, Wang FZ, Chan P, Fan M.Hypoxic preconditioning up-regulates glucose transport activity and glucose transporter (GLUT1 and GLUT3) gene expression after acute anoxic exposure in the cultured rat hippocampal neurons and astrocytes. Brain Research. 2008,1211:22-29.SCI
46. Ning Li,Yanning Cai,Xiaohong Zuo,Shengli Xu,Yanli Zhang,Piu Chan,Yu Alex Zhang.Suprachiasmatic nucleus slices induce molecular oscillations in fibroblasts. Biochem Biophys Res Commun. 2008,377(4):1179-1184.SCI
47. Liu D, Jin L, Wang H, Zhao H, Zhao C, Duan C, Lu L, Wu B, Yu S, Chan P, Li Y,Yang H.Silencing alpha-Synuclein Gene Expression Enhances Tyrosine Hydroxylase Activity in MN9D Cells. Neurochem Research. 2008,33(7):1401-1409.SCI
48. Jing-fang Yang,Jian-yu Li,Yong-jie LI,Tao Wu,Yan-li Zhang,Biao Chen*.DYT1 mutations amongst early onset primary dystonia patients in China. Chin Med Sci J. 2008,23(1):38-43.
49. 宣琪，徐胜利，周明，催叶青，陈彪.人类黑质神经元衰老性变化的体视学研究. 首都医科大学学报. 2008,29（3）:270-273.
50. 吴晓莉，陈彪*.自发性低颅压症的影像学特征及硬膜外注液治疗的效果. 临床神经病学杂志. 2008,21(5):374-375.
51. 杨静芳，李建宇，李勇杰，张燕莉，陈彪*.原发性肌张力障碍患者DYT1基因突变分析. 中华医学杂志. 2007,87(33):2324-2327.无
52. 王莉莉，徐胜利，陈彪*.表没食子儿茶素没食子酸酯对6-OHDA导致的多巴胺能神经细胞损伤的保护作用. 中国行为医学科学. 2007,16:311-314.无
53. 王莉莉，陈彪*，徐胜利.EGCG对帕金森病神经保护作用的信号转导机制。. 中国现代神经疾病杂志. 2007,7:14-17.无
54. Yu S, Li X, Liu GW, Han JY, Zhang CY, Li YH, Xu SL, Liu C, Gao YP, Yang H, Ueda K, Chan P*.Extensive nuclear localization of α-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody. Neuroscience. 2007,145:539-555.SCI
55. Wu T, Zang Y, Wang L, Long X, Hallett M, Chen Y, Li K, Chan P*.Aging influence on functional connectivity of the motor network in the resting state. Neurosci Lett. 2007,422:164-8.SCI
56. 何延波，陈彪*.α-synuclein基因多态性与帕金森病. 中华神经科杂志. 2007,40:133-135.SCI
57. 郑晓立、陈彪*.美国神经病学学会公布的最新帕金森病循证医学指南. 中国现代神经疾病杂志. 2007,7(1):36－38.无
58. Wu T, Zang Y, Wang L, Long X, Li K, Chan P*.Normal aging decreases regional homogeneity of the motor areas in the resting state. Neurosci Lett. 2007,423:189-193.SCI
59. 孙高慧 陈彪*.POLG基因与帕金森病关系的研究进展. 中华神经科杂志. 2007,40(7):490-492.无
60. 陈新平，陈彪，马秋兰，汤哲，张丽梅，冯秀丽，董秀敏，杨静芳.中国北方老年人多巴胺受体D2基因多态性与吸烟的相关性研究. 现代预防医学. 2006,33(7):1057-1060.无
61. 孙虹，陈彪，孙菲，张新卿，汤哲，刘宏军，方向华.合并静止性震颤的原发性震颤患者临床特点分析. 中国神经精神疾病杂志. 2006,32(4):314-317.无
62. 蔡彦宁，左晓虹，刘姝，谢淑，温玫，陈彪.利用荧光定量聚合酶链反应检测小鼠纹状体中Per1基因的表达规律. 首都医科大学学报. 2006,27(1):63-66.无
63. 曹三勇，徐胜利，陈彪.蛋白酶体抑制剂对神经细胞的双重作用. 脑与神经疾病杂志. 2006,14(4):274-298.无
64. 张晨，李昕，李尧华，韩俊燕，陈彪，于顺.细胞外α-突触核蛋白对MES23.5多巴胺能神经细胞的促增殖作用. 首都医科大学学报. 2006,27(5):616-619.无
65. Feng Wang, Xiuli Feng, Jinhong Ma, Haiqiang Zou, Piu Chan. A common A340T variant in PINK1 gene associated with late-onset Parkinson’s disease in Chinese. Neurosci Lett. 2006,410(2):121－5.SCI
66. 王雪梅，陈彪.组蛋白脱乙酰化酶在α-突触核蛋白抑制酪氨酸氧化酶表达中的作用. 首都医科大学学报. 2006,27(4):476-479.无
67. 杨静芳，梁秀玲，马守忠，王丽娟，陈嵘，陈彪.74例肝豆状核变性患者中ATP7B基因七种新突变的发现. 中华神经科杂志. 2006,39(10):673-677.无
68. 孙虹，陈彪，孙菲，张新卿，汤哲，刘宏军，吴晓光，方向华.北京地区中老年人群原发性震颤的流行病学研究. 中华神经科杂志. 2006,39 (3):189-192.无
69. 刘姝, 陈彪, 蔡彦宁, 温玫, 左晓虹.人外周血hPer1基因的节律表达的研究. 中国现代医学. 2006,16(3):381-383.无
70. 左晓虹，陈彪，蔡彦宁，吴燕川，刘姝，谢淑，温玫.MPTP对C57小鼠纹状体DA释放节律的影响. 首都医科大学学报. 2006,27(1):66-69.无
71. Xin Li, Yao-Hua Li, Jun-Yan Han, Shun Yu, Biao Chen.cDNA cloning, prokaryotic expression and purification of rat α-synuclein. Neuroscience Bulletin. 2006,22(1):29－33.无
72. Chunlin Zou, Po Man Suen, Ying Zhang, Zeyu Wang, Piu Chan, Po Sing Leung, Y. Alex Zhang.Isolation and in vitro characterization of pancreatic progenitor cells from the islets of diabetic monkey models. Int J Biochem Cell Biol. 2006,38(5-6):973-84.SCI
73. Fuchun Lin, Chunshui Yu, Tianzi Jiang, Kuncheng Li, Chaozhe Zhu, Wanlin Zhu, Wen Qin, Yunyun Duan, Yun Xuan, Hong Sun, and Piu Chan.Discriminative analysis of relapsing neuromyelitis optica and relapsing-remitting multiple sclerosis based on two-dimensional histogram from diffusion tensor imaging. Neuroimage. 2006,31(2):543-9.SCI
74. Shengli Xu, Ming Zhou, Shun Yu, Yanning Cai , Alex Zhang, Kenji Ueda, Piu Chan.Oxidative stress induces nuclear translocation of c-terminus of α-synuclein in dopaminergic cells. Biochem Biophys Res Commun. 2006, 342(1):330-5.SCI
75. Yue Feng, Chen Biao, Wu Di, Dong Kai, Zeng Si-en, Zhang Yu.Biological Properties of neural progenitor cells isolated from the hippocampus of adult cynomolgus monkeys. Chin Med J. 2006,119(2):110-116.SCI
76. Fa-GuoZhao,Yin-HuaWang,Jing-FangYang,Qiu-LanMa,ZheTang,Xiu-MinDong,Piu Chan.Association between acyl-coenzyme A: cholesterol acyltransterase gene and risk for Alzheimer’s disease in Chinese. Neuroscience Letters. 2005,(17-20):1-4.SCI
77. Tao Wu, Piu Chan, Mark Hallett.Ageing influence on automatic movement. Physiology News. 2005,(59):30-31.无
78. 李尧华，于顺，高亚萍，柳川，左晓虹，陈彪.揭示α-突触核蛋白与帕金森病的关系：α-突触核蛋白单克隆抗体的研究. 中国临床康复. 2005,1(9-7):44-46.无
79. 徐胜利，周明，刘平，张丽艳，徐艳玲，张愚，陈彪.6-羟多巴诱导大鼠黑质的持续胶质细胞反应. 神经解剖学杂志. 2005,3（21-2）:133-138.无
80. 徐胜利，周明，张丽燕，徐艳玲，陈彪. 氧化应激诱导多巴胺能MES23.5细胞α-突触核蛋白C-末端片段核转位. 解剖学报. 2005,8（36-4）:337-341.无
81. 温玫，蔡彦宁，田娜，刘桓，陈彪.成纤维细胞生长因子受体3 基因荧光定量聚合酶链反应检测方法的建立. 中华检验医学杂志. 2005,5（28-5）:499-500.无
82. 左晓虹，陈彪，蔡彦宁，刘姝.小鼠纹状体多巴胺水平的节律性变化. 中国临床康复. 2005,4（9-13）:28-36.无
83. 万华瑛，陈彪，杨静芳，董秀敏.烟酰胺嘌呤二核苷酸磷酸：醌氧化还原酶1基因多态性与认知功能减退和老年性痴呆的关系. 中国医学科学院学报. 2005,1（27-3）:285-288.无
84. Shun Yu, Kenji Ueda, Piu Chan.α-Synuclein and Dopamine Metabolism. Molecular Neurobiology. 2005,31(1-3):243-254.SCI
85. 张新卿，陈彪，汤哲，刘宏军，李坤成，刘树良.轻度认知功能损害诊断：脑血管病因素对神经心理学指标的影响. 中国神经精神疾病杂志. 2005,（31-5）:362-364.无
86. 刘姝，蔡彦宁，冯秀丽，温玫，左晓虹，陈彪.改进竞争性RT-PCR法在定量PER1基因表达中的应用. 基础医学与临床. 2005,5（25-5）:309-413.无
87. 江小华，徐群渊，杨晖，陈彪.中国人群单胺氧化酶-B基因多态性与帕金森病相关性研究. 中华神经科杂志. 2005,37（3）:239-242.无
88. 邹海强，陈彪，冯秀丽，李昕，董秀敏.parkin 基因启动子区- 258T/ G多态性增加晚发帕金森病的发病风险. 中华神经科杂志. 2004,37(2):122-125.无
89. 杜万良，王荫华，陈彪.PRKCG基因多态性扫描及其与帕金森病的相关性研究. 中国康复理论与实践. 2004,10(3):152-157.无
90. 关云谦，陈彪，邹春林，张愚.胚胎干细胞“五步法”体外诱导成为神经细胞的实验观察. 中国临床康复. 2004,8（10）:1851-1853.无
91. 周景升，张新卿，王丽冬，孟潮，楚长彪，陈彪.电话版常识-记忆-注意测验用于痴呆的信效度研究. 中国心理卫生杂志. 2004,18（9）:624-627.无
92. 蔡彦宁，温玫，左晓红，田娜，陈彪.阿尔茨海默病患者皮质额叶基因表达谱研究. 中国临床康复. 2004,8（28）:6068-6070.无
93. 杨静芳，江晓华，梁秀龄，王丽娟，陈嵘，李昕，陈彪.变性高效液相色谱在检测肝豆状核变性基因突变中的作用. 中国神经精神疾病杂志. 2004, 30（2）:124-126.无
94. 刘平，刘焯霖，杨静芳，陈彪.早发性帕金森病与细胞色素P4501A1和N-乙酰基转移酶2基因多态性及个体易感危险性. 中国临床康复. 2004,8（4）:621-623.无
95. 江小华，杨慧，杨静芳，王海涛，徐群渊，陈彪.中国人NAD（P）H：醌氧化还原酶基因多态性与帕金森病遗传易感性的关系. 中华医学遗传学杂志. 2004,21（2）:120-123.无
96. 于顺，刘雪梅，李尧华，吕国蔚，陈彪.重复急性低氧对小鼠大脑皮质中α-突触核蛋白表达的影响. 生理学报. 2004,56（2）:263-268.无
97. 傅求真，徐胜利，左晓红，徐燕玲，陈彪.1-甲基-4-苯基-吡啶盐致多巴胺能细胞系MES23.5死亡机制. 细胞生物学杂志. 2004,26（5）:539-543.无
98. 杨文明，陈彪，韩明向，鲍远程，张波，胡兵，刘爱萍.实验性阿尔茨海默病大鼠模型行为学、神经生化学病理学特征. 中国临床康复. 2004,8（19）:3737-3738.无
99. 孟琛，汤哲，方向华，刘向红，吴晓光，刘宏军，刁丽君，陈彪.北京老年人认知功能对生存率影响的八年随访观察. 中华老年医学杂志. 2004,23（7）:507-509.无
100. 邹海强，陈彪，马秋兰，李昕，杨静芳，冯秀丽，董秀敏，李勇杰.Parkin基因新的多态位点IVS3-21T-C增加早发性帕金森病的发病风险. 中华医学遗传学杂志. 2004,21（3）:106-110.无
101. 蔡彦宁，温玫，张愚，陈彪.帕金森病患者尾状核中基因表达谱的研究. 中华医学杂志. 2004,84（14）:1191-1193.无
102. 于泓，李尧华，冯秀丽，吴燕川，周虹，陈彪.MES23.5 细胞酪氨酸羟化酶的种属来源及其重组酶的活性测定. 中国生物化学与分子生物学报. 2004,20 (1):95～100.无
103. 黄越，杨静芳，齐晓涟，王育琴，王维治，陈彪.CYP2C19 和CYP2C9 基因型与苯妥英血药浓度关系的研究. 中华医学杂志. 2004,84(20):1686-1688.无
104. 邹海强，陈彪，彭晓霞，冯秀丽，董秀敏.Parkin 基因S/ N167 多态性与帕金森病发病风险的Meta分析. 中国循证医学杂志. 2004,4(3):157-163.无
105. Shun Yu, Xiaohong Zuo, Yaohua Li, Chen Zhang, Ming Zhou, Yu Alex Zhang, Kenji Ueda, Piu Chan.Inhibition of tyrosine hydroxylase expression in α-synuclein-transfected dopaminergic neuronal cells. Neuroscience Letters. 2004,367(1): 34-39.SCI
106. 江小华，杨慧，杨静芳，董秀敏，徐群渊，陈彪.单胺氧化酶A基因Fnu4H酶切位点多态性与帕金森病相关性研究. 中华医学遗传学杂志. 2003,20(3):211-214.无
107. 王育琴，齐晓涟，黄越，陈彪.丙戊酸药物浓度与CYP2C19基因多态性关系的研究. 中国医院药学杂志. 2003,23(11):670-673.无
108. 江小华，徐群渊，杨静芳，董秀敏，杨慧，陈彪.中国人单胺氧化酶A基因的EcoRV酶切位点多态性与帕金森病的相关性. 中国神经科学杂志. 2003,19(4):255-258.无
109. Qiu-Lan Ma, Piu Chan, Mitsunobu Yoshii and Kenji Ueda. Alpha-Synuclein aggregation and neurodegenerative diseases: Is there a common pathogenesis? . Journal of Alzheimer’s Disease. 2003,5:139-148.无
110. 马秋兰，杨静芳，邵明，董秀敏，陈彪.阿尔茨海默病与NQ01和ApoE基因多态性关联分析. 中华医学杂志. 2003,83（24）:2124-2127 .无
111. 刘雪梅，于顺，李尧华，周茗，左晓虹，吕国蔚，陈彪.抗人α-synuclein多克隆抗体的制备和鉴定. 首都医科大学学报. 2003,24（1）:7-10.无
112. Jian Wang, Zhuo-Lin Liu, Biao Chen.Association study of dopamine D2, D3 receptor gene polymorphisms with motor fluctuations in PD . NEUROLOGY. 2002,58(5): 837-838.SCI
113. Jie Wu, Piu Chan, Katherine M. Schroeder, Kevin Ellsworth and L. Donald L. Partridge.1-Methyl-4-phenylpridinium (MPP+)-induced functional run-down of GABA(A) receptor-mediated currents in acutely dissociated dopaminergic neurons. Journal of Neurochemistry . 2002,83(1):87-99.SCI
114. Matt Farrer, Piu Chan, Rong Chen, Louis Tan , Sarah Lincoln, Dena Hernandez, Lysia Forno, Katrina Gwinn-Hardy, Leonard Petrucelli, Jennifer Hussey, Andrew Singleton, Caroline Tanner, John Hardy, J. William Langston.Lewy bodies and parkinsonism in families with parkin mutations. Annals of Neurology. 2001,50(3):293-300.SCI
115. Jian Wang, Zhuo-Lin Liu, Biao Chen.Dopamine D5 receptor gene polymorphism and the risk of levodopa-induced motor fluctuations in patients with Parkinson's disease. Neurosci Lett . 2001,308(1):21-24.SCI
116. Jian Wang, Zhuolin Liu, Piu Chan. Lack of association between cytochrome P450 2E1 gene polymorphisms and Parkinson's disease in a Chinese population. Mov Disord. 2000,15(6):1267-1269.SCI
117. Piu Chan, Caroline M. Tanner, Xin Jiang, and J. William Langston. Failure to find the alpha-synuclein gene missense mutation (G209A) in 100 patients with younger onset Parkinson’s disease. Neurology. 1998,50:513-514.SCI
118. P. Chan, X. Jiang, L. S. Forno, D. A. Di Monte, C. M. Tanner, and J. W. Langston.Absence of mutations in the coding region of the alpha-synuclein gene in pathologically-proven Parkinson’s disease. Neurology. 1998, 50:1136-1137.SCI
119. Piu Chan, Donato A. Di Monte, J. William Langston and Ann Marie Janson. (+) MK-801 does not prevent MPTP-induced loss of nigral neurons in mice . J Pharmacol Exp Ther. 1997,280:439-446.SCI
120. P. Chan, C. W. Shults, C. M. Tanner, J. S. Fink, M. Kurth, K. L. Marek, L. W.Elmer and Parkinson Study Group: Use of a clinical trials population in genetic research. Am J Hum Genet. 1995, 57(4suppl):A316.SCI
121. Piu Chan, Donato A. Di Monte, Jin-Jun Luo, Louis E. DeLanney, Ian Irwin, and J. William Langston.Rapid ATP loss cause by methamphetamine in the mouse striatum: relationship between energy impairment and dopaminergic neurotoxicity. J Neurochem. 1994,62:2484-2487.SCI
122. Piu Chan, Donato A. Di Monte, J. William Langston.Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine *(MPTP) on levels of glutamate and aspartate in the mouse brain. Brain Res. 1994,647:249-254.SCI
123. Piu Chan, Yi Li, Zhong Zheng, Ping Hu, Sabine D. Sarbach and David Guez.Neurologic and histologic evaluation of almitrine +rabasine (Duxil) in middle cerebral artery occlusion in cats. Eur J Pharmacol. 1993, 231:175-182.SCI
124. Chan P, Langston JW, Di Monte DA.MK-801 temporarily prevents MPTP-induced acute dopamine depletion and MPP+elimination in the mouse striatum. J Pharmacol Exp Ther. 1993,267:1515-1520.SCI
125. Piu Chan, J. William Langston, Ian Irwin, Louis E. DeLanney, and Donato A. Di Monte. 2-Deoxyglucose enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced ATP loss in the mouse brian. J Neurochem. 1993, 61:610-616.SCI
126. Piu Chan, Louis E. DeLanney, Ian Irwin, J. William Langston, and Donato Di Monte.MPTP-induced ATP loss in mouse brain. Ann NY Acad Sci. 1992, 648:306-308.SCI
127. Donato A. Di Monte, Piu Chan, and Martha S. Sandy. Glutathione in Parkinson’s disease: a link between oxidative stress and mitochondrial damage? . Ann Neurol. 1992,32:S111-S115.SCI
128. Piu Chan, Louis E. DeLanney, Ian Irwin, J. William Langston, and Donato Di Monte.Rapid ATP depletion caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain. J Neurochem. 1991,57:348-351.SCI
129. Caroline M. Tanner, B. Chen, J. A. Cohen, W. Wang and M. Peng, B. C. Summerville, Z. Liu and X. Liang, L. C. Kao and C. G. Goetz.. Dietary antioxidant vitamines and the risk of developing Paikinson’s disease. Neurology. 1989,39(Suppl 1):229.SCI
130. C. M. Tanner, B. Chen, W. Wang, M. Peng, Z. Liu, X. Liang, L. C. Kao, D. W. Gilley, C. G. Goetz, and B. S. Schoenberg.Environmental factors and Parkinson’s disease: A case control study in China. Neurology. 1989, 39:660-664.SCI
131. Caroline M. Tanner, Biao Chen, Wen-Zhi Wang, David W. Gilley, Man-Ling Peng, Zho-Lin Liu and Xue-Ling Liang, Li Chiung Kao and Christopher G. Goetz, Bruce S.Environmental factors and Parkinson’s disease (PD): A case control study in China. Neurology. 1988, 38(Suppl 1):349.SCI
主编或副主编的著作/译著
1. 《帕金森病》,主编,中国医药科技出版社,200912
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15. 帕金森病的遗传和环境危险因素研究 教育部科技成果 三等奖 1990