姓名：张蕊 性别：女 职称：主任医师、副教授 招生院所：附属儿童医院 招生类型：专业学位(硕) 招生专业：儿内科学(硕) 研究方向名称：儿童组织细胞疾病（噬血细胞综合征和朗格罕细胞组织细胞增生症）及慢性活动性EBV感染的发病机制与难治复发病人的治疗研究 电子信箱：ruizh1973@163.com


社会任职
个人简历
1. 199009-199507:郑州大学医学部 学习
2. 199509-199807:郑州大学医学部 学习
3. 199809-200107:首都医科大学 学习
4. 200108-200508:首都医科大学附属北京儿童医院 任职
5. 200509-200602:澳大利亚昆士兰大学 访问
6. 200603-202004:首都医科大学附属北京儿童医院 任职
7. 201011-201012:美国St. Jude儿童医院 学习
8. 201309-201311:纽约儿童医院 学习
重要学术论文
1. Lei Cui, Li Zhang, Hong-Hao Ma, Chan-Juan Wang, Dong Wang, Hong-Yun Lian, Wei-Jing Li, Qing Zhang, Na Li, Tian-You Wang*, Zhi-Gang Li*, Rui Zhang*.Circulating cell-free BRAFV600E during chemotherapy is associated with prognosis of children with Langerhans cell histiocytosis. Haematologica. 2020,epub:Epub ahead of print.SCI
2. Chellapandian D, Hines MR, Zhang R, Jeng M, van den Bos C, Santa-María López V, Lehmberg K, Sieni E, Wang Y, Nakano T, Williams JA, Fustino NJ, Astigarraga I, Dunkel IJ, Abla O, van Halteren AGS, Pei D, Cheng C, Weitzman S, Sung L, Nichols KE.A multicenter study of patients with multisystem Langerhans cell histiocytosis who develop secondary hemophagocytic lymphohistiocytosis. Cancer. 2019,125(6):963-971.SCI
3. Wei A, Ma H, Li Z, Zhang L, Zhang R*, Wang T*.Successful treatment of a child with idiopathic multicentric Castleman disease associated with hemophagocytic lymphohistiocytosis using tocilizumab. Pediatr Blood Cancer. 2019,66(7):e27759.SCI
4. 廉红云，张莉，李志刚，马宏浩，王冬，赵云泽，赵晓曦，王天有，张蕊*.儿童颅面骨受累的朗格罕细胞组织细胞增生症临床分析. 中华实用儿科临床杂志. 2019,34(15):1151-1155.核心期刊
5. Zhao XX, Lian HY, Zhang L, Ma HH, Wang D, Zhao YZ, Liu ZW, Wang TY, Zhang R*, Li ZG*.Significance of serum ferritin level in hemophagocytic lymphohistiocytosi. Int J Lab Hematol. 2019,41(4):503-508.SCI
6. Zhang L, Li Z, Liu W, Ma H, Wang T*, Zhang R*.Genetic characterization of pediatric primary hemophagocytic lymphohistiocytosis in China: a single-center study. Ann Hematol. 2019,98(10):2303-231.SCI
7. Wei A, Ma H, Li Z, Zhang L, Zhang R*, Wang T*.Type-IV Glycogen Storage Disease Associated with Hemophagocytic lymphositiocytosis: a case report. Journal of Pediatric Hematology and Oncology. 2019,epub:epub.SCI
8. Yun‐Ze Zhao, Hua Cheng, Chang‐Hong Ding, Hong‐Hao Ma, Tong‐Li Han, Jiu‐Wei Li, Dong Wang, Zhi‐Gang Li, Tian‐You Wang, Rui Zhang*.Neurological Abnormality Could be the First and Only Symptom of Familial Hemophagocytic Lymphohistiocytosis, Report of Two Families.. Chinese Medical Journal. 2018,131(24):3004-3006.SCI
9. Dong Wang, Lei Cui, Zhi-Gang Li, Li Zhang, Hong-Yun Lian, Hong-Hao Ma, Yun-Ze Zhao, Xiao-Xi Zhao, Tian-You Wang, Rui Zhang*.Clinical Research of Pulmonary Langerhans Cell Histiocytosis in Children. . Chinese Medical Journal. 2018,131(15):1794-1798.SCI
10. Yun-Ze Zhao, Lei Cui, Zhi-Gang Li, Li Zhang, Hong-Yun Lian, Hong-Hao Ma, Dong Wang, Xiao-Xi Zhao, Tian-You Wang, Rui Zhang*.Central Nervous System Involvement in 179 Chinese Children with Hemophagocytic Lymphohistiocytosis. Chinese Medical Journal. 2018,131(15):1786-1792.SCI
11. 马宏浩, 王天有, 张莉, 廉红云, 王冬, 赵云泽, 赵晓曦, 张蕊*.儿童EB病毒相关噬血细胞性淋巴组织细胞增生症的预后相关危险因素分析. 北京医学. 2018,40(7):622-628.核心期刊
12. 张莉,廉红云,马宏浩,高超,王冬,王天有,张蕊*.儿童朗格罕细胞组织细胞增生症217例临床分析. 中华实用儿科临床杂志. 2017,32(15):1141-1144.核心期刊
13. 张莉,廉红云,马宏浩,高超,王冬,王天有,张蕊*.BRAF基因V600E突变在儿童朗格罕细胞组织细胞增生症中的临床意义. 中国小儿血液与肿瘤杂志. 2017,22(4):190-193.核心期刊
14. 马宏浩, 王天有, 张莉, 廉红云, 王冬, 赵云泽, 赵晓曦, 张蕊*.儿童甲状腺受累的朗格罕细胞组织细胞增生症 8例临床分析. 中华实用儿科临床杂志. 2017,32(20):1552-1555.核心期刊
15. Rui Zhang, Ling Jin, Hua Cheng, Jing Yang, Yan-Long Duan, Shuang Huang, Yong-Hong Zhang*.Reversible Posterior Leukoencephalopathy Syndrome Sometimes Could be Irreversible: A Case Following Tumor Lysis Syndrome in Childhood Burkitt’s Lymphoma. Chinese Medical Journal. 2016,31(22):480-483.SCI
16. 赵云泽，王天有，张莉，廉红云，马宏浩，王冬，赵晓曦，张蕊*.中枢神经系统受累对噬血细胞性淋巴组织细胞增生症（HLH）患儿预后的影响. 中华实用儿科临床杂志. 2016,31（22）:1737-1740.核心期刊
17. 马宏浩，王天有，张莉，廉红云，王冬，赵云泽，赵晓曦，张蕊*.儿童难治性EB病毒相关噬血细胞性淋巴组织细胞增生症-治疗中病情暴发发3例并文献综述. 中华实用儿科临床杂志. 2016,31(22):1745-1748.核心期刊
主编或副主编的著作/译著
重要奖项