姓名：李志刚 性别：男 职称：研究员、教授 招生院所：附属儿童医院 招生类型：科学学位(博) 科学学位(硕) 招生专业：儿内科学(博) 儿内科学(硕) 研究方向名称：血液系统肿瘤复发与耐药机制研究 电子信箱：ericlzg70@hotmail.com


社会任职
1. 《中华儿科杂志》通讯编委
2. 中国医疗保健国际交流促进会理事、儿科学分会委员兼秘书长
3. 中华医学会儿科学分会精准医学委员会副主任委员
4. 中国研究型医院学会儿童肿瘤专业委员会副主任委员
5. 中国妇幼保健协会妇儿健康临床标准与规范分会儿童临床实验医学标准与规范专业学组委员
个人简历
1. 199008-199506:北京医科大学基础医学系 学习
2. 199508-199707:首都医科大学附属北京儿童医院 任职
3. 199708-200006:首都医科大学 学习
4. 200006-202004:首都医科大学附属北京儿童医院 任职
5. 201008-201311:首都医科大学 学习
重要学术论文
1. Xiao-Xi Zhao, Hong-Yun Lian, Li Zhang, Hong-Hao Ma, Dong Wang, Yun-Ze Zhao, Zeng-Wu Liu, Tian-You Wang, Rui Zhang*, Zhi-Gang Li*.Significance of serum ferritin level in hemophagocytic lymphohistiocytosis diagnosis. International Journal of Laboratory Hematology. 2019,41(4):503-508.SCI
2. 王婵娟,崔蕾*,李伟京,赵晓曦,高超,吴敏媛,王天有,李志刚*.Ig/TCR基因重排在儿童急性T淋巴细胞白血病中的表达模式特点. 中国循证儿科杂志. 2019,14(2):106-111.核心期刊
3. Lei Cui#,ZhiGang Li#,YiHuan Chai#,Jie Yu#,Ju Gao#,XiaoFan Zhu#,RunMing Jin#,XiaoDong Shi#,LePing Zhang#,YiJin Gao#,RuiDong Zhang,HuYong Zheng,ShaoYan Hu,YingHui Cui,YiPing Zhu,Yao Zou,Margaret H.L.Ng,Yan Xiao,JunHui Li,YongHong Zhang,HaiLong He,Ying Xian,TianYou Wang*,ChiKong Li*,MinYuan Wu*.Outcome of children with newly diagnosed acute lymphoblastic leukemia treated with CCLG-ALL 2008: The first nation-wide prospective multicenter study in China. American Journal of Hematology. 2018,93(7):913-920.SCI
4. 金芬芬,梅妍妍,王凯玲,王婵娟,吴敏媛,崔蕾,李志刚*.联合检测E2F3a和CASP8AP2表达水平在儿童急性淋巴细胞白血病预后中的意义. 中华实用儿科临床杂志. 2018,33(9):697-701.核心期刊
5. Fei Fei Liu#,Kai Ling Wang#,Li Ping Deng,Xiao Liu,Min Yuan Wu,Tian You Wang,Lei Cui*,Zhi Gang Li*.Transcription factor E2F3a regulates CASP8AP2 transcription and enhances sensitivity to chemotherapeutic drugs in acute lymphoblastic leukemia. Cancer Cell International. 2018,18:40.SCI
6. Weijing Li,Lei Cui,Chao Gao,Shuguang Liu,Xiaoxi Zhao,Ruidong Zhang,Huyong Zheng,Minyuan Wu,Zhigang Li*.DNMT3A mutations in Chinese childhood acute myeloid leukemia. Medicine (Baltimore). 2017,96(31):e7620.SCI
7. 崔蕾，高超，张瑞东，焦莹，李伟京，赵晓曦，刘曙光，岳志霞，郑胡镛，邓国仁，吴敏媛，李志刚*，贾弘禔*.Low expressions of ARS2 and CASP8AP2 predict relapse and poor prognosis in pediatric acute lymphoblastic leukemia patients treated on China CCLG-ALL 2008 protocol. Leukemia Research. 2015,39(2):115-123.SCI
8. Weijing Li, Chao Gao, Lei Cui, Shuguang Liu, Xiaoxi Zhao, Ruidong Zhang, Minyuan Wu, Huyong Zheng, Guoren Deng, Zhigang Li*, Quangeng Zhang*.DNMT3A mutations and prognostic significance in childhood acute lymphoblastic leukemia. Leukemia & Lymphoma. 2015,56(4):1066-1071.SCI
9. 高超，刘曙光，张瑞东，李伟京，赵晓曦，崔蕾，吴敏媛，郑胡镛，李志刚*.NOTCH1 mutations are associated with favourable long-term prognosis in paediatric T-cell acute lymphoblastic leukaemia: a retrospective study of patients treated on BCH-2003 and CCLG-2008 protocol in China. British Journal of Haematology. 2014,166(2):221-228.SCI
10. 王凯玲，梅妍妍，崔蕾，赵晓曦，李伟京，高超，刘曙光，焦莹，刘飞飞，吴敏媛，丁卫，李志刚*.E2F3a gene expression has prognostic significance in childhood acute lymphoblastic leukemia. European Journal of Haematology. 2014,93(4):281-289.SCI
11. Yanyan Mei，Chao Gao，Kailing Wang，Lei Cui，Weijing Li，Xiaoxi Zhao，Feifei Liu，Minyuan Wu，Guoren Deng，Wei Ding，Hongti Jia，Zhigang Li*.Effect of microRNA-210 on prognosis and response to chemotherapeutic drugs in pediatric acute lymphoblastic leukemia. Cancer Science. 2014,105(4):463-472.SCI
12. Ying Jiao, Lei Cui, Chao Gao, Weijing Li, Xiaoxi Zhao, Shuguang Liu, Minyuan Wu, Guoren Deng, Zhigang Li*.CASP8AP2 is a promising prognostic indicator in pediatric acute lymphoblastic leukemia. Leukemia Research. 2012,36(1):67-71.SCI
13. Chao Gao，Xiao-Xi Zhao，Wei-Jing Li，Lei Cui，Wei Zhao，Shu-Guang Liu，Zhi-Xia Yue，Ying Jiao，Min-Yuan Wu，Zhi-Gang Li*.Clinical features, early treatment responses, and outcomes of pediatric acute lymphoblastic leukemia in China with or without specific fusion transcripts: A single institutional study of 1,004 patients. American Journal of Hematology. 2012,87(11):1022-1027.SCI
14. Wei-Jing Li, Lei Cui, Chao Gao, Xiao-Xi Zhao, Shu-Guang Liu, Yan-Ping Xing, Rui-Dong Zhang, Da-Wei Zhang, Bin Wang, Zhi-Gang Li*, Min-Yuan Wu.MRD analysis and treatment outcome in three children with SET-NUP214-positive hematological malignancies. International Journal of Laboratory Hematology. 2011,33(6):e25-e27.SCI
15. Shu-Guang Liu, Zhi-Gang Li*, Lei Cui, Chao Gao, Wei-Jing Li, Xiao-Xi Zhao.Effects of methylenetetrahydrofolate reductase gene polymorphisms on toxicities during consolidation therapy in pediatric acute lymphoblastic leukemia in a Chinese population. Leukemia & Lymphoma. 2011,52(6):1030–1040.SCI
16. Bo-Wei Han, Dan-Dan Feng, Zhi-Gang Li(并列第一作者), Xue-Qun Luo, Hua Zhang, Xiao-Juan Li, Xing-Ju Zhang, Ling-Ling Zheng, Cheng-Wu Zeng, Kang-Yu Lin, Peng Zhang, Ling Xu, Yue-Qin Chen*.A set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALL. Human Molecular Genetics. 2011,20(24):4903–4915.SCI
17. 崔蕾，李志刚*，吴敏媛，李伟京，高超，邓国仁.Combined analysis of minimal residual disease at two time points and its value for risk stratification in childhood B-lineage acute lymphoblastic leukemia. Leukemia Research. 2010,34(10):1314-1319.SCI
18. Zhigang Li, Wei Zhang, Minyuan Wu, Shanshan Zhu, Chao Gao, Lin Sun, Ruidong Zhang, Nan Qiao, Huiling Xue, Yamei Hu, Shilai Bao*, Huyong Zheng*, Jing-Dong J. Han*.Gene expression-based classification and regulatory networks of pediatric acute lymphoblastic leukemia. Blood. 2009,114(20):4486-4493.SCI
主编或副主编的著作/译著
重要奖项
1. 儿童急性淋巴细胞白血病规范化诊断、治疗及早期评估研究 北京市科学技术奖 三等奖 201401