姓名：孔雅娴 性别：女 职称：研究员、副教授 招生院所：地坛医院 招生类型：科学学位(硕) 招生专业：免疫学(硕) 研究方向名称：感染免疫 电子信箱：kongyaxian@ccmu.edu.cn


社会任职
1. 中国性病艾滋病防治协会学术委员会青年委员
2. 中国研究型医院学会肝病专业委员会青年委员
个人简历
1. 199909-200407:北京大学医学部 本科生
2. 200409-200907:北京大学 博士研究生（直博）
3. 200908-201010:首都医科大学附属北京地坛医院 研究实习员
4. 201010-201410:首都医科大学附属北京地坛医院 助理研究员
5. 201411-201911:首都医科大学附属北京地坛医院 副研究员，副教授
6. 201411-201508:美国宾夕法尼亚州立大学医学院 访问
7. 201712-201812:美国宾夕法尼亚州立大学医学院 访问
8. 201911-202004:首都医科大学附属北京地坛医院 研究员
重要学术论文
1. Liu X, Li M, Wang X, Dang Z, Jiang Y, Wang X, Kong Y*, Yang Z*.PD-1+ TIGIT+ CD8+ T cells are associated with pathogenesis and progression of patients with hepatitis B virus-related hepatocellular carcinoma. Cancer Immunol Immunother. 2019,68(12):2041-2054.SCI
2. Kong Y, Jia B, Zhao C, Claxton DF, Sharma A, Annageldiyev C, Fotos JS, Zeng H, Paulson RF, Prabhu KS, Zheng H*.Downregulation of CD73 associates with T cell exhaustion in AML patients. Journal of Hematology & Oncology. 2019,12(1):40.SCI
3. Kong Y#, Tian Y#, Hao Y#, Chong X, Xiao J, Yang D, Song C, Han J, Dai G, Zhang F, Zheng H, Zhao H*, Zeng H*.Two types of poor immunological responder showing distinct responses to long-term HAART. International journal of infectious diseases. 2019,86:178-187.SCI
4. Song Y#, Wang B#, Song R, Hao Y, Wang D, Li Y, Jiang Y, Xu L, Ma Y, Zheng H, Kong Y*, Zeng H*.T-cell Immunoglobulin and ITIM Domain Contributes to CD8+ T-cell Immunosenescence. Aging Cell. 2018,17(2):12716.SCI
5. Zhang H#, He G#, Kong Y#, Chen Y, Wang B, Sun X, Jia B, Xie X, Wang X, Chen D, Wei L, Zhang M, Zeng H*, Chen H* .Tumour-activated liver stromal cells regulate myeloid-derived suppressor cells accumulation in the liver. Clin Exp Immunol. 2017,188(1):96-108.SCI
6. Zhu L#, Kong Y#, Zhang J, Claxton DF, Ehmann WC, Rybka WB, Palmisiano ND, Wang M, Jia B, Bayerl M, Schell TD, Hohl RJ, Zeng H*, Zheng H*.Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia. Journal of Hematology & Oncology. 2017,10(1):124.SCI
7. Kong Y#, Li Y, Zhang W, Yuan S, Winkler R, Kröhnert U, Han J, Lin T, Zhou Y, Miao P, Wang B, Zhang J, Yu Z, Zhang Y, Kosan C*, Zeng H*.Sepsis-Induced Thymic Atrophy is Associated with Defects in Early Lymphopoiesis. Stem Cells. 2016,34(12):2902-2915.SCI
8. Kong Y#, Zhu L#, Schell TD, Zhang J, Claxton DF, Ehmann WC, Rybka W, George MR, Zeng H*, Zheng H*.T-cell Immunoglobulin and ITIM Domain (TIGIT) Associates with CD8+ T cell Exhaustion and Poor Clinical Outcome in AML Patients. Clinical Cancer Research. 2016,22(12):3057-66.SCI
9. Kong Y*#, Wang H, Wang S, Tang N.FTY720, a sphingosine-1 phosphate receptor modulator, improves liver fibrosis in a mouse model by impairing the motility of bone marrow-derived mesenchymal stem cells. Inflammation. 2014,37(4):1326-1336.SCI
10. Kong Y#*, Wang H#, Lin T, Wang S.Sphingosine-1-phosphate/S1P receptors signaling modulates cell migration in human bone marrow-derived mesenchymal stem cells. Mediators of Inflammation. 2014,2014:565369.SCI
11. Li C#, Kong Y#, Wang H, Wang S, Yu H, Liu X, Yang L, Jiang X, Li L*, Li L*.Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis. Journal of Hepatology. 2009,50(6):1174-83.SCI
主编或副主编的著作/译著
重要奖项